BRPI0923199A2 - métodos e composições para detecção de anticorpos com fixação de complemento. - Google Patents
métodos e composições para detecção de anticorpos com fixação de complemento.Info
- Publication number
- BRPI0923199A2 BRPI0923199A2 BRPI0923199A BRPI0923199A BRPI0923199A2 BR PI0923199 A2 BRPI0923199 A2 BR PI0923199A2 BR PI0923199 A BRPI0923199 A BR PI0923199A BR PI0923199 A BRPI0923199 A BR PI0923199A BR PI0923199 A2 BRPI0923199 A2 BR PI0923199A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- methods
- fixing antibodies
- detecting complement
- complement
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11894908P | 2008-12-01 | 2008-12-01 | |
| US61/118,949 | 2008-12-01 | ||
| PCT/US2009/065984 WO2010065425A1 (en) | 2008-12-01 | 2009-11-25 | Methods and compositions for detection of complement fixing antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0923199A2 true BRPI0923199A2 (pt) | 2016-02-16 |
| BRPI0923199B1 BRPI0923199B1 (pt) | 2020-10-20 |
| BRPI0923199B8 BRPI0923199B8 (pt) | 2021-07-27 |
Family
ID=42233567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0923199A BRPI0923199B8 (pt) | 2008-12-01 | 2009-11-25 | método para determinar a presença de anticorpos de fixação de complemento |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10338080B2 (pt) |
| EP (2) | EP2353005B1 (pt) |
| JP (2) | JP5792626B2 (pt) |
| CN (2) | CN105866426B (pt) |
| AU (1) | AU2009322607B2 (pt) |
| BR (1) | BRPI0923199B8 (pt) |
| CA (1) | CA2740192C (pt) |
| WO (1) | WO2010065425A1 (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3722320A3 (en) | 2012-10-25 | 2020-12-30 | Bioverativ USA Inc. | Anti-complement c1s antibodies and uses thereof |
| DK2914291T3 (da) | 2012-11-02 | 2022-05-16 | Bioverativ Usa Inc | Anti-komplement-c1s-antistoffer og anvendelser deraf |
| WO2014151763A1 (en) * | 2013-03-14 | 2014-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting donor-specific antibodies and systems for practicing the same |
| WO2014160376A1 (en) * | 2013-03-14 | 2014-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting complement fixing and non-complement fixing antibodies and systems for practicing the same |
| DK3019240T3 (da) | 2013-07-09 | 2024-06-03 | Annexon Inc | Anti-komplementfaktor C1Q antistoffer og anvendelser deraf |
| SI3215527T1 (sl) * | 2014-11-05 | 2025-04-30 | Annexon, Inc. | Humanizirana protitelesa proti komplementnemu faktorju C1q in njihova uporaba |
| CA2981321A1 (en) | 2015-04-06 | 2016-10-13 | True North Therapeutics, Inc. | Humanized anti-c1s antibodies and methods of use thereof |
| US10527613B2 (en) | 2015-11-10 | 2020-01-07 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarker detection methods and systems and kits for practicing same |
| EP3380518B1 (en) | 2015-11-24 | 2026-03-25 | Annexon, Inc. | Anti-complement factor c1q fab fragments and uses thereof |
| CA3010587C (en) | 2015-12-03 | 2021-08-17 | NJ Sharing Network | Igg subtyping assay for identifying transplantable tissue samples |
| EP3239711B1 (en) | 2016-04-27 | 2019-12-25 | JIMRO Co., Ltd. | Method for measuring anti-drug antibody |
| WO2017187656A1 (ja) * | 2016-04-27 | 2017-11-02 | 株式会社Jimro | 抗医薬品抗体の測定方法 |
| CN110300520B (zh) | 2016-10-12 | 2022-10-04 | 美国比奥维拉迪维股份有限公司 | 抗C1s抗体及其使用方法 |
| US20190383805A1 (en) * | 2017-01-25 | 2019-12-19 | Northeastern University | Electrochemical Antibody-Based Biosensor |
| CN114910635B (zh) * | 2017-10-26 | 2025-05-02 | 科美诊断技术股份有限公司 | 一种无基质效应的均相免疫检测试剂盒及其应用 |
| CN107976535B (zh) * | 2017-11-03 | 2020-03-20 | 科美诊断技术股份有限公司 | 一种检测样本中目标IgM抗体的均相免疫检测试剂盒及其使用方法和应用 |
| CN109991405B (zh) * | 2017-12-29 | 2023-01-24 | 上海索昕生物科技有限公司 | 一种免疫检测试剂盒及其应用 |
| JP7153494B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
| JP7153493B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
| DE202020006093U1 (de) * | 2019-05-06 | 2025-04-09 | The Regents Of The University Of California | Nicht-HLA-Marker der Transplantatabstoßung |
| CN111812336A (zh) * | 2020-08-10 | 2020-10-23 | 苏州康和顺医疗技术有限公司 | 用于检测冠状病毒抗体的检测试剂盒及其制备方法 |
| EP4226155A1 (en) * | 2020-10-09 | 2023-08-16 | Takeda Vaccines, Inc. | Methods for determining complement-fixing antibodies |
| US20240142451A1 (en) * | 2021-03-31 | 2024-05-02 | Takeda Vaccines, Inc. | Methods for characterizing the immune response of a subject to a dengue virus composition |
| EP4089413A1 (en) * | 2021-05-12 | 2022-11-16 | Cisbio Bioassays | Method for determining the binding of an antibody to the complement component 1q (c1q) |
| US12486322B2 (en) | 2021-12-13 | 2025-12-02 | Annexon, Inc. | Anti-complement factor C1q antibodies with single binding arms and uses thereof |
| CN118604345A (zh) * | 2024-05-31 | 2024-09-06 | 上海览屹医药科技有限公司 | 酶联免疫方法测定单克隆抗体浓度 |
| CN120142127A (zh) * | 2025-05-16 | 2025-06-13 | 上海荻硕贝肯基因科技有限公司 | 一种供者特异性抗体的检测方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US5035995A (en) * | 1984-10-02 | 1991-07-30 | Calpis Food Industry Co., Ltd. | Test method involving substance-conjugated complement component C1q |
| JPS6184560A (ja) * | 1984-10-02 | 1986-04-30 | Karupisu Shokuhin Kogyo Kk | 補体結合性抗体の測定法 |
| JPS61245060A (ja) | 1985-04-23 | 1986-10-31 | Takara Shuzo Co Ltd | ヒト補体１ｑ定量用キツト及び定量法 |
| JPS6225994A (ja) * | 1985-05-30 | 1987-02-03 | ジエネテイツク システムズ コ−ポレイシヨン | Ｈｌａタイプ分け用モノクロ−ナル抗体 |
| IL84160A0 (en) * | 1986-10-16 | 1988-03-31 | Vasocor | Method and kit for immune complex assay |
| US5176998A (en) | 1986-12-01 | 1993-01-05 | The Scripps Research Institute | Cell surface antigen detection method |
| US5223397A (en) | 1991-06-05 | 1993-06-29 | Sangstat Medical Corporation | Soluble hla cross-match |
| US5270169A (en) * | 1992-06-23 | 1993-12-14 | Sangstat Medical Corporation | Detection of HLA antigen-containing immune complexes |
| AU687010B2 (en) | 1992-07-17 | 1998-02-19 | Dana-Farber Cancer Institute | Method of intracellular binding of target molecules |
| US5851829A (en) | 1993-07-16 | 1998-12-22 | Dana-Farber Cancer Institute | Method of intracellular binding of target molecules |
| GB9502112D0 (en) | 1995-02-03 | 1995-03-22 | British Biocell Int | Assay device and method |
| US6159748A (en) * | 1995-03-13 | 2000-12-12 | Affinitech, Ltd | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry |
| US5948627A (en) | 1997-05-30 | 1999-09-07 | One Lambda | Immunobead flow cytometric detection of anti-HLA panel-reactive antibody |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| AU759779B2 (en) | 1997-10-31 | 2003-05-01 | Genentech Inc. | Methods and compositions comprising glycoprotein glycoforms |
| CN1423130A (zh) | 2002-04-26 | 2003-06-11 | 帕弗瑞生物技术(北京)有限公司 | 流式测定固定补体抗体的hla交叉配型方法和试剂盒 |
| CN1444044A (zh) | 2002-06-18 | 2003-09-24 | 帕弗瑞生物技术(北京)有限公司 | 以酶联免疫测定为基础的hla补体依赖性细胞毒性抗体检测方法和试剂盒 |
| TW200508609A (en) | 2003-07-15 | 2005-03-01 | Bioarray Solutions Ltd | Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays |
| US20050277158A1 (en) * | 2004-06-10 | 2005-12-15 | Ge Chen | Method and kit for donor specific complement-fixing antibodies crossmatch |
| US7799556B2 (en) * | 2004-06-17 | 2010-09-21 | George Dacai Liu | System and method for antigen structure-independent detection of antigens captured on antibody arrays |
| AU2006244486A1 (en) | 2005-05-06 | 2006-11-16 | Platypus Technologies, Llc | Liquid crystal based analyte detection |
| CN100354629C (zh) * | 2005-10-17 | 2007-12-12 | 中国人民解放军第三军医大学第一附属医院 | 用胶体金标记补体第一成分q亚单位做指示剂的蛋白芯片/微阵列检测系统及检测方法 |
| GB0618496D0 (en) * | 2006-09-20 | 2006-11-01 | Common Services Agency | Blood typing |
| JP2008100986A (ja) * | 2006-09-21 | 2008-05-01 | Takahiro Ochi | Ｃ１ｑ結合物質、ならびにその使用 |
| US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
| JP2009080019A (ja) | 2007-09-26 | 2009-04-16 | Nippon Sekijiyuujishiya | 蛍光ビーズを用いた免疫複合体検出による抗体解析法 |
| DE102008045696A1 (de) | 2008-09-04 | 2010-03-11 | Drk Blutspendedienst West Ggmbh | Granulozyten HNA-3a/b-Antigen |
| CA2763199A1 (en) | 2009-05-29 | 2010-12-02 | The Regents Of The Univeristy Of California | B cell signature associated with tolerance in transplant recipients |
| US20120065092A1 (en) | 2010-09-14 | 2012-03-15 | Wai Hobert | Fusion analyte cytometric bead assay, and systems and kits for performing the same |
| US20140249051A1 (en) | 2011-08-30 | 2014-09-04 | The Governors Of The University Of Alberta | Method and system for abo antibody detection and characterization |
| WO2014151763A1 (en) | 2013-03-14 | 2014-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting donor-specific antibodies and systems for practicing the same |
| WO2014160376A1 (en) | 2013-03-14 | 2014-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting complement fixing and non-complement fixing antibodies and systems for practicing the same |
-
2009
- 2009-11-25 CA CA2740192A patent/CA2740192C/en active Active
- 2009-11-25 WO PCT/US2009/065984 patent/WO2010065425A1/en not_active Ceased
- 2009-11-25 CN CN201610218019.2A patent/CN105866426B/zh active Active
- 2009-11-25 EP EP09830911.5A patent/EP2353005B1/en active Active
- 2009-11-25 EP EP18190547.2A patent/EP3460480B1/en active Active
- 2009-11-25 US US13/129,554 patent/US10338080B2/en active Active
- 2009-11-25 AU AU2009322607A patent/AU2009322607B2/en active Active
- 2009-11-25 BR BRPI0923199A patent/BRPI0923199B8/pt not_active IP Right Cessation
- 2009-11-25 JP JP2011538701A patent/JP5792626B2/ja active Active
- 2009-11-25 CN CN2009801446394A patent/CN102203610A/zh active Pending
-
2014
- 2014-09-09 JP JP2014183579A patent/JP2015007651A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009322607B2 (en) | 2015-05-14 |
| US10338080B2 (en) | 2019-07-02 |
| EP3460480B1 (en) | 2022-11-02 |
| EP3460480A1 (en) | 2019-03-27 |
| CA2740192A1 (en) | 2010-06-10 |
| CN105866426B (zh) | 2018-11-23 |
| US20110281757A1 (en) | 2011-11-17 |
| WO2010065425A1 (en) | 2010-06-10 |
| JP2012510618A (ja) | 2012-05-10 |
| CN105866426A (zh) | 2016-08-17 |
| EP2353005B1 (en) | 2018-10-03 |
| EP2353005A1 (en) | 2011-08-10 |
| JP2015007651A (ja) | 2015-01-15 |
| CN102203610A (zh) | 2011-09-28 |
| BRPI0923199B8 (pt) | 2021-07-27 |
| BRPI0923199B1 (pt) | 2020-10-20 |
| JP5792626B2 (ja) | 2015-10-14 |
| EP2353005A4 (en) | 2012-10-17 |
| CA2740192C (en) | 2019-12-31 |
| AU2009322607A1 (en) | 2010-06-10 |
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 20/10/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/11/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 16A ANUIDADE. |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2856 DE 30-09-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |