BRPI0923572A2 - enzima tioesterase engenheirada que converte um substrato acil-acp c10, c12 ou c14 em um derivado de ácido graxo, polinucleotídeo codificando a tioesterase engenheirada, vetor de expressão, célula hospedeira, método de fabricação de composição de derivado de ácido graxo c10, c12 ou c14, método de produção de uma composição de derivado de ácido graxo - Google Patents

enzima tioesterase engenheirada que converte um substrato acil-acp c10, c12 ou c14 em um derivado de ácido graxo, polinucleotídeo codificando a tioesterase engenheirada, vetor de expressão, célula hospedeira, método de fabricação de composição de derivado de ácido graxo c10, c12 ou c14, método de produção de uma composição de derivado de ácido graxo

Info

Publication number
BRPI0923572A2
BRPI0923572A2 BRPI0923572A BRPI0923572A BRPI0923572A2 BR PI0923572 A2 BRPI0923572 A2 BR PI0923572A2 BR PI0923572 A BRPI0923572 A BR PI0923572A BR PI0923572 A BRPI0923572 A BR PI0923572A BR PI0923572 A2 BRPI0923572 A2 BR PI0923572A2
Authority
BR
Brazil
Prior art keywords
fatty acid
acid derivative
engineered thioesterase
derivative composition
acyl
Prior art date
Application number
BRPI0923572A
Other languages
English (en)
Inventor
Hom Louis
F Alibhai Murtaza
Trinh Na
Original Assignee
Ls9 Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ls9 Inc filed Critical Ls9 Inc
Priority to BR122019009204-4A priority Critical patent/BR122019009204B1/pt
Publication of BRPI0923572A2 publication Critical patent/BRPI0923572A2/pt
Publication of BRPI0923572B1 publication Critical patent/BRPI0923572B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10L—FUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G OR C10K; LIQUIFIED PETROLEUM GAS; USE OF ADDITIVES TO FUELS OR FIRES; FIRE-LIGHTERS
    • C10L1/00—Liquid carbonaceous fuels
    • C10L1/02—Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0923572-8A 2008-12-23 2009-12-23 Enzima tioesterase modificada que converte um substrato acil-acp c10, c12 ou c14 em um derivado de ácido graxo, polinucleotídeo codificando a tioesterase modificada, vetor de expressão, célula hospedeira de microrganismo e método de fabricação de composição de derivado de ácido graxo c10, c12 ou c14 BRPI0923572B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122019009204-4A BR122019009204B1 (pt) 2008-12-23 2009-12-23 Célula hospedeira de microrganismo compreendendo enzima tioesterase modificada e cultura de célula compreendendo a referida célula

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14060008P 2008-12-23 2008-12-23
US61/140,600 2008-12-23
PCT/US2009/069356 WO2010075483A2 (en) 2008-12-23 2009-12-23 Methods and compositions related to thioesterase enzymes

Publications (2)

Publication Number Publication Date
BRPI0923572A2 true BRPI0923572A2 (pt) 2017-05-30
BRPI0923572B1 BRPI0923572B1 (pt) 2019-07-30

Family

ID=42091570

Family Applications (2)

Application Number Title Priority Date Filing Date
BR122019009204-4A BR122019009204B1 (pt) 2008-12-23 2009-12-23 Célula hospedeira de microrganismo compreendendo enzima tioesterase modificada e cultura de célula compreendendo a referida célula
BRPI0923572-8A BRPI0923572B1 (pt) 2008-12-23 2009-12-23 Enzima tioesterase modificada que converte um substrato acil-acp c10, c12 ou c14 em um derivado de ácido graxo, polinucleotídeo codificando a tioesterase modificada, vetor de expressão, célula hospedeira de microrganismo e método de fabricação de composição de derivado de ácido graxo c10, c12 ou c14

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR122019009204-4A BR122019009204B1 (pt) 2008-12-23 2009-12-23 Célula hospedeira de microrganismo compreendendo enzima tioesterase modificada e cultura de célula compreendendo a referida célula

Country Status (11)

Country Link
US (5) US9175234B2 (pt)
EP (2) EP3564345A1 (pt)
CN (3) CN102325864B (pt)
AP (1) AP2011005777A0 (pt)
AU (2) AU2009329970B2 (pt)
BR (2) BR122019009204B1 (pt)
CA (2) CA2747516C (pt)
ES (1) ES2730713T3 (pt)
MX (3) MX368526B (pt)
WO (1) WO2010075483A2 (pt)
ZA (1) ZA201105380B (pt)

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