BRPI0925040A2 - Produção e extração de procianidinas a partir da cultura celular de plantas - Google Patents

Produção e extração de procianidinas a partir da cultura celular de plantas

Info

Publication number
BRPI0925040A2
BRPI0925040A2 BRPI0925040-9A BRPI0925040A BRPI0925040A2 BR PI0925040 A2 BRPI0925040 A2 BR PI0925040A2 BR PI0925040 A BRPI0925040 A BR PI0925040A BR PI0925040 A2 BRPI0925040 A2 BR PI0925040A2
Authority
BR
Brazil
Prior art keywords
procyanidins
extraction
production
cell culture
plant cell
Prior art date
Application number
BRPI0925040-9A
Other languages
English (en)
Inventor
Mylavarapu Venkatramesh
D Ry Wagner
Sonia Lall
Frederic Lejard
Sung-Yong Yoon
Original Assignee
Dianaplantsciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dianaplantsciences Inc filed Critical Dianaplantsciences Inc
Publication of BRPI0925040A2 publication Critical patent/BRPI0925040A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/005Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0025Culture media for plant cell or plant tissue culture
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/10Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits
    • A01H1/101Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/002Culture media for tissue culture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0925040-9A 2009-04-03 2009-05-04 Produção e extração de procianidinas a partir da cultura celular de plantas BRPI0925040A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16659109P 2009-04-03 2009-04-03
PCT/US2009/042722 WO2010114567A1 (en) 2009-04-03 2009-05-04 Production and extraction of procyanidins from plant cell cultures

Publications (1)

Publication Number Publication Date
BRPI0925040A2 true BRPI0925040A2 (pt) 2015-07-21

Family

ID=42828607

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0925040-9A BRPI0925040A2 (pt) 2009-04-03 2009-05-04 Produção e extração de procianidinas a partir da cultura celular de plantas

Country Status (7)

Country Link
US (1) US8568798B2 (pt)
EP (2) EP2414509B1 (pt)
JP (2) JP5789595B2 (pt)
KR (2) KR20160054015A (pt)
CN (1) CN102414312A (pt)
BR (1) BRPI0925040A2 (pt)
WO (1) WO2010114567A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9167840B2 (en) 2009-04-03 2015-10-27 DianaPlantScience, Inc. Production and extraction of procyanidins from plant cell cultures
EP2670247A4 (en) * 2011-02-04 2014-09-24 Dianaplantsciences S A S POLYPHENOL PREPARATION BY VACCINIUM MYRTILLUS CELL CULTURES
WO2013170155A2 (en) 2012-05-11 2013-11-14 The Hershey Company Methods of purifying and identifying the presence of and levels of procyanidin oligomeric compounds
EP2900078A1 (en) * 2012-09-26 2015-08-05 Dianaplantsciences, Inc. Novel food compositions of whole plant cells
CN104020227B (zh) * 2014-05-21 2015-08-19 浙江理工大学 一种用组织培养法生产甾体生物碱的碱含量测定方法
WO2016046375A1 (en) * 2014-09-25 2016-03-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) Theobroma cacao extract for use in the treatment or prevention of receptor tyrosine kinases related disorders
CN106109512A (zh) * 2016-06-27 2016-11-16 郭迎庆 一种可可多酚咀嚼片的制备方法
CN106244515A (zh) * 2016-08-04 2016-12-21 福建省农业科学院农业工程技术研究所 一种提高刺葡萄细胞培养物花青素含量的方法
FR3061176B1 (fr) 2016-12-22 2020-09-11 Antofenol Preparation d'un extrait de biomasse seche riche en polyphenols
EP3980038A4 (en) * 2019-06-07 2023-04-12 Mars, Incorporated COCOA CELL SUSPENSION PROTOCOL
CN112243860B (zh) * 2020-10-27 2021-05-25 中国科学院昆明植物研究所 一种云南梧桐组培快繁方法
EP4176710A1 (en) 2021-11-03 2023-05-10 Zürcher Hochschule Für Angewandte Wissenschaften Cocoa plant cell culture processing methods and products obtained by the same
EP4461129A1 (en) 2023-05-09 2024-11-13 ZHAW - Zürcher Hochschule für Angewandte Wissenschaften Edible plant cell culture biomass based on fruit endocarp and/or seed explants and methods of its preparation

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4306022A (en) * 1980-03-11 1981-12-15 Cornell Research Foundation, Inc. Cocoa bean cell culture
US4545147A (en) 1983-08-08 1985-10-08 Purdue Research Foundation Asexual embryogenesis of callus from theobroma cacao L.
US7264951B1 (en) 1992-02-20 2007-09-04 Phyton, Inc. Enhanced production of taxol and taxanes by cell cultures of Taxus species
US5407816A (en) 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species
US5554645A (en) 1994-10-03 1996-09-10 Mars, Incorporated Antineoplastic cocoa extracts and methods for making and using the same
KR960037826A (ko) 1995-04-27 1996-11-19 김경환 택서스속 식물세포의 반연속식 배양방법
JPH09175982A (ja) 1995-12-28 1997-07-08 Nikka Uisukii Kk 化粧品
US6297273B1 (en) 1996-04-02 2001-10-02 Mars, Inc. Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions
WO1997036497A2 (en) 1996-04-02 1997-10-09 Mars, Incorporated Cocoa extract compounds and methods for making and using the same
US6312753B1 (en) 1996-09-06 2001-11-06 Mars, Incorporated Cocoa components, edible products having enriched polyphenol content, methods of making same and medical uses
KR100266448B1 (ko) 1997-06-26 2000-09-15 박종헌 식물세포 배양 중의 온도변화에 의한 택솔의 대량생산 방법
US6150587A (en) * 1997-06-27 2000-11-21 The Penn State Research Foundation Method and tissue culture media for inducing somatic embryogenesis, Agrobacterium-mediated transformation and efficient regeneration of cacao plants
EP1014969B1 (en) 1997-09-09 2008-11-12 Rutgers, The State University of New Jersey Plant proanthocyanidin extract effective at inhibiting adherence of bacteria with p-type fimbriae to surfaces
US8507018B2 (en) 1998-03-12 2013-08-13 Mars, Incorporated Products containing polyphenol(s) and L-arginine and methods of use thereof
US6627232B1 (en) 2000-06-09 2003-09-30 Mars Incorporated Method for extracting cocoa procyanidins
US7314634B2 (en) 2002-02-22 2008-01-01 Steven Hernandez Use of polyphenols to treat skin conditions
CA2507704A1 (en) * 2002-12-02 2004-06-17 Mars, Incorporated Flavanols and procyanidins promote homeostasis
US7320797B2 (en) 2003-08-29 2008-01-22 Bioderm Research Antiaging cosmetic delivery systems
EP1718754A1 (en) * 2004-02-23 2006-11-08 Chromatin, Inc. Plants modified with mini-chromosomes
US7390641B2 (en) * 2004-05-25 2008-06-24 Council Of Scientific And Industrial Research Production of peroxidase from plant cell and callus cultures
US20060078872A1 (en) 2004-10-12 2006-04-13 Atsushi Taguchi Cell-preservation liquid
FR2885299B1 (fr) 2005-05-03 2009-11-20 Nuxe Lab Utilisation de polyphenols de cacao pour reguler la pigmentation de la peau
US7566401B2 (en) 2005-10-03 2009-07-28 Kelm Mark A Process for separating and isolating xanthines, individual polar protic monomers, and polar protic oligomers
AU2006331531B2 (en) 2005-12-23 2013-01-31 Mars, Incorporated Skin protection and improvement
US20080003314A1 (en) 2006-06-29 2008-01-03 Indivi Wine Usa, Llc Germinated seeds possessing increased water-soluble polyphenols and method of manufacturing
GB0719544D0 (en) 2007-10-08 2007-11-14 Barry Callebaut Ag Cocoa extract and use thereof
US20080274234A1 (en) 2007-05-01 2008-11-06 Carter Robert Miller Processing cocoa beans and other seeds
ATE527873T1 (de) 2007-12-04 2011-10-15 Nestec Sa Somatische kakao-embryogenese

Also Published As

Publication number Publication date
EP2966165A1 (en) 2016-01-13
EP2414509A1 (en) 2012-02-08
JP2015109863A (ja) 2015-06-18
KR20120059451A (ko) 2012-06-08
US20120021080A1 (en) 2012-01-26
KR20160054015A (ko) 2016-05-13
JP5789595B2 (ja) 2015-10-07
WO2010114567A1 (en) 2010-10-07
EP2414509B1 (en) 2015-09-23
EP2414509A4 (en) 2012-10-17
US8568798B2 (en) 2013-10-29
JP2012522504A (ja) 2012-09-27
CN102414312A (zh) 2012-04-11

Similar Documents

Publication Publication Date Title
BRPI0925040A2 (pt) Produção e extração de procianidinas a partir da cultura celular de plantas
SI2507506T1 (sl) Z morjem gnano energetsko postrojenje
EP2451259A4 (en) MODULE AND MANUFACTURING METHOD THEREFOR
DK2414531T3 (da) Forbedret biomasseforbehandlingsproces
BRPI0916499A2 (pt) método de produção de biomassa
BR112012003719A2 (pt) método de pré-tratamento de biomassa de plantas
BRPI0916498A2 (pt) Método de produção de biomassa enriquecida com carboidratos e método de fragmentação simultânea e extração seletiva de lignina
IL215935A (en) Method and production plant for producing ammonia
BRPI0914824A2 (pt) produção de proteína melhorada e armazenagem em plantas
BRPI1011588A2 (pt) hidrólise de biomassa
LT2411028T (lt) Terapija, skirta skatinti ląstelių augimą
BRPI1008370A2 (pt) Biomassa sacarificante
PL2475872T3 (pl) Fundament dla wieży turbiny wiatrowej
BRPI0822933A2 (pt) Regulador do crescimento de plantas
EP2463257A4 (en) TRANSPARENT ZIRCONIUM SINTERED BODY, METHOD FOR ITS MANUFACTURE AND USE
HRP20181637T1 (hr) Postrojenje za proizvodnju čelika
PL2658984T3 (pl) Wydajna hydroliza lignocelulozy ze zintegrowanym wytwarzaniem enzymu
FI20095062A0 (fi) Kasvien viljelymenetelmä
EP2399595A4 (en) IMMUNOSTIMULATING COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF
BR112012001669A2 (pt) produção de elevação
DK2236676T3 (da) Fundamentlegeme til et vindenergianlæg
BR112012008085A2 (pt) usina elétrica de poço
EP2624704A4 (en) Production and Extraction of Procyanidins from Plant Cell Culture
IL219540A (en) Fiber-reinforced structures and processes for their manufacture
IT1392177B1 (it) Impianto e processo per la produzione di biogas

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]