BRPI1003988A2 - Método para uso de 4-aminopiridina ao longo de períodos crônicos, e, método para tratamento durável de paciente com esclerose múltipla - Google Patents

Método para uso de 4-aminopiridina ao longo de períodos crônicos, e, método para tratamento durável de paciente com esclerose múltipla

Info

Publication number
BRPI1003988A2
BRPI1003988A2 BRPI1003988-0A BRPI1003988A BRPI1003988A2 BR PI1003988 A2 BRPI1003988 A2 BR PI1003988A2 BR PI1003988 A BRPI1003988 A BR PI1003988A BR PI1003988 A2 BRPI1003988 A2 BR PI1003988A2
Authority
BR
Brazil
Prior art keywords
multiple sclerosis
sclerosis patient
durable treatment
over chronic
aminopyridine
Prior art date
Application number
BRPI1003988-0A
Other languages
English (en)
Inventor
Thomas C Wessel
Andrew Blight
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Publication of BRPI1003988A2 publication Critical patent/BRPI1003988A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
BRPI1003988-0A 2009-09-04 2010-09-06 Método para uso de 4-aminopiridina ao longo de períodos crônicos, e, método para tratamento durável de paciente com esclerose múltipla BRPI1003988A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24010009P 2009-09-04 2009-09-04
PCT/US2010/047932 WO2011029082A1 (en) 2009-09-04 2010-09-06 Durable treatment with 4-aminopyridine in patients with demyelination

Publications (1)

Publication Number Publication Date
BRPI1003988A2 true BRPI1003988A2 (pt) 2015-08-25

Family

ID=43649681

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1003988-0A BRPI1003988A2 (pt) 2009-09-04 2010-09-06 Método para uso de 4-aminopiridina ao longo de períodos crônicos, e, método para tratamento durável de paciente com esclerose múltipla

Country Status (11)

Country Link
US (8) US20130267566A1 (pt)
EP (2) EP3210606A1 (pt)
KR (2) KR20120050512A (pt)
CN (1) CN102143686A (pt)
AR (1) AR078323A1 (pt)
BR (1) BRPI1003988A2 (pt)
IL (1) IL214560A0 (pt)
MY (1) MY174829A (pt)
TW (1) TW201125562A (pt)
UY (1) UY32879A (pt)
WO (1) WO2011029082A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
EP2850044B1 (en) * 2012-05-17 2017-05-17 The University of Chicago Use of fluorinated derivatives of 4-aminopyridine in therapeutics and medical imaging
US9617215B2 (en) 2012-05-17 2017-04-11 The University Of Chicago Use of fluorinated derivatives of 4-aminopyridine in therapeutics and medical imaging
RU2686116C1 (ru) * 2018-06-27 2019-04-24 Общество С Ограниченной Ответственностью "Инновационные Фармакологические Разработки" (Ооо "Ифар") Способ количественного определения 4-амино-1-(3-нитро-2-оксо-1-фенил-1,2-дигидро-1,6-нафтиридин-5-ил)пиридиний хлорида в биологических средах
US11564565B2 (en) 2020-04-02 2023-01-31 Massachusetts Institute Of Technology Chip-scale optical coherence tomography engine
KR20250095010A (ko) 2023-12-19 2025-06-26 김인우 슬라브 배관 내화채움재 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1082804A (en) 1912-11-19 1913-12-30 Gerald G Griffin Confetti-machine.
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
US7884079B2 (en) * 2004-12-27 2011-02-08 Miller Landon C G 4-aminopyridine and a pharmaceutical composition for treatment of neuronal disorders
WO2010093839A1 (en) * 2009-02-11 2010-08-19 Acorda Therapeutics, Inc. Compositions and methods for extended therapy with aminopyridines

Also Published As

Publication number Publication date
US20170266171A1 (en) 2017-09-21
EP2473039A4 (en) 2013-01-09
US20160184286A1 (en) 2016-06-30
WO2011029082A1 (en) 2011-03-10
CN102143686A (zh) 2011-08-03
EP2473039A1 (en) 2012-07-11
US20190000820A1 (en) 2019-01-03
TW201125562A (en) 2011-08-01
US20170035742A1 (en) 2017-02-09
AR078323A1 (es) 2011-11-02
KR20120050512A (ko) 2012-05-18
US20200113883A1 (en) 2020-04-16
MY174829A (en) 2020-05-18
US20190247378A1 (en) 2019-08-15
KR20170120708A (ko) 2017-10-31
WO2011029082A8 (en) 2011-05-12
US20130267566A1 (en) 2013-10-10
EP3210606A1 (en) 2017-08-30
UY32879A (es) 2011-03-31
IL214560A0 (en) 2011-09-27
US20140206728A1 (en) 2014-07-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 3A, 4A E 5A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.