BRPI1005327A2 - derivados de triazolopiridina como inibidores de p38 map quinase - Google Patents

derivados de triazolopiridina como inibidores de p38 map quinase

Info

Publication number
BRPI1005327A2
BRPI1005327A2 BRPI1005327A BRPI1005327A BRPI1005327A2 BR PI1005327 A2 BRPI1005327 A2 BR PI1005327A2 BR PI1005327 A BRPI1005327 A BR PI1005327A BR PI1005327 A BRPI1005327 A BR PI1005327A BR PI1005327 A2 BRPI1005327 A2 BR PI1005327A2
Authority
BR
Brazil
Prior art keywords
kinase inhibitors
map kinase
triazolopyridine derivatives
triazolopyridine
derivatives
Prior art date
Application number
BRPI1005327A
Other languages
English (en)
Inventor
Waszkowycz Bohdan
Woo Chi-Kit
Finch Harry
Knight Jamie
Montana John
Bodil Van Niel Monique
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42232647&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1005327(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0902651A external-priority patent/GB0902651D0/en
Priority claimed from GB0908069A external-priority patent/GB0908069D0/en
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of BRPI1005327A2 publication Critical patent/BRPI1005327A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI1005327A 2009-02-17 2010-02-16 derivados de triazolopiridina como inibidores de p38 map quinase BRPI1005327A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0902651A GB0902651D0 (en) 2009-02-17 2009-02-17 Pharmaceutical compounds and compositions
GB0908069A GB0908069D0 (en) 2009-05-11 2009-05-11 Pharmaceutical compounds and compositions
PCT/GB2010/050257 WO2010094956A1 (en) 2009-02-17 2010-02-16 Triazolopyridine derivatives as p38 map kinase inhibitors

Publications (1)

Publication Number Publication Date
BRPI1005327A2 true BRPI1005327A2 (pt) 2019-09-24

Family

ID=42232647

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1005327A BRPI1005327A2 (pt) 2009-02-17 2010-02-16 derivados de triazolopiridina como inibidores de p38 map quinase

Country Status (19)

Country Link
US (1) US8557797B2 (pt)
EP (1) EP2398798A1 (pt)
JP (1) JP2012517992A (pt)
KR (1) KR20110116030A (pt)
CN (2) CN102395586A (pt)
AU (1) AU2010215261A1 (pt)
BR (1) BRPI1005327A2 (pt)
CA (1) CA2752693A1 (pt)
CL (1) CL2011001977A1 (pt)
CO (1) CO6420344A2 (pt)
EA (1) EA201190119A1 (pt)
IL (1) IL214658A0 (pt)
MA (1) MA33128B1 (pt)
MX (1) MX2011008496A (pt)
PE (1) PE20120655A1 (pt)
SG (1) SG174134A1 (pt)
TN (1) TN2011000380A1 (pt)
WO (1) WO2010094956A1 (pt)
ZA (1) ZA201105993B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2701594C (en) * 2007-10-24 2014-02-18 Merck Sharp & Dohme Corp. Heterocycle phenyl amide t-type calcium channel antagonists
GB201009731D0 (en) 2010-06-10 2010-07-21 Pulmagen Therapeutics Inflamma Kinase inhibitors
MX2014000963A (es) 2011-07-26 2014-03-27 Gruenenthal Gmbh Derivados de carboxamida y urea aromaticos biciclicos sustituidos como ligandos del receptor de vanilloide.
KR20140105459A (ko) * 2011-12-09 2014-09-01 키에시 파르마슈티시 엣스. 피. 에이. 키나아제 억제제
ES2612259T3 (es) 2011-12-09 2017-05-16 Chiesi Farmaceutici S.P.A. Inhibidores de cinasa
KR20140103925A (ko) 2011-12-09 2014-08-27 키에시 파르마슈티시 엣스. 피. 에이. 4-히드록시-1,2,3,4-테트라히드로나프탈렌-1-일 우레아 및 호흡기 질환의 치료에서의 이들의 용도
CA2879431A1 (en) 2012-07-17 2014-01-23 Washington University Anti-mucus drugs and uses therefor
HK1219101A1 (zh) * 2013-06-06 2017-03-24 奇斯药制品公司 作为p38map激酶抑制剂的[1，2，4]三唑并[4，3-a]吡啶的衍生物
US9359354B2 (en) 2013-06-06 2016-06-07 Chiesi Farmaceutici S.P.A. Kinase inhibitors
HK1220459A1 (zh) 2013-06-06 2017-05-05 奇斯药制品公司 激酶抑制剂
GB201321742D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
UY36390A (es) * 2014-11-05 2016-06-01 Flexus Biosciences Inc Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
MX2017005462A (es) 2014-11-05 2017-07-28 Flexus Biosciences Inc Agentes inmunorreguladores.
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2019071144A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. USE OF P38 INHIBITORS TO REDUCE DUX4 EXPRESSION

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
EP0842195A1 (en) 1995-07-06 1998-05-20 Zeneca Limited Peptide inhibitors of fibronectine
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
YU25500A (sh) 1999-05-11 2003-08-29 Pfizer Products Inc. Postupak za sintezu analoga nukleozida
GB0028383D0 (en) 2000-11-21 2001-01-03 Novartis Ag Organic compounds
EP1241176A1 (en) 2001-03-16 2002-09-18 Pfizer Products Inc. Purine derivatives for the treatment of ischemia
CA2470813A1 (en) 2001-12-20 2003-07-03 Bayer Healthcare Ag 1,4-dihydro-1,4-diphenylpyridine derivatives
JP2006517580A (ja) * 2003-02-14 2006-07-27 ファイザー・プロダクツ・インク 抗炎症化合物としてのトリアゾロピリジン
SE0302487D0 (sv) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
JP2007535565A (ja) 2004-04-30 2007-12-06 バイエル ファーマシューティカルス コーポレーション 癌の治療に有用な置換ピラゾリル尿素誘導体
ES2308523T3 (es) 2004-06-23 2008-12-01 Eli Lilly And Company Inhibidores de quinasa.
EP1609789A1 (en) 2004-06-23 2005-12-28 Eli Lilly And Company Ureido-pyrazole derivatives and their use as kinase inhibitors
DE602005010714D1 (de) 2004-08-12 2008-12-11 Pfizer Der p38-map-kinase
GB0418015D0 (en) * 2004-08-12 2004-09-15 Pfizer Ltd New compounds
US20090215817A1 (en) 2004-08-18 2009-08-27 Pfizer Inc Novel Triazolopyridine Compounds for the Treatment of Inflammation
GB0502258D0 (en) 2005-02-03 2005-03-09 Argenta Discovery Ltd Compounds and their use
EP1984363A1 (en) 2006-02-09 2008-10-29 Pfizer Limited Triazolopyridine compounds
SG174069A1 (en) 2006-08-21 2011-09-29 Array Biopharma Inc 4-substituted phenoxyphenylacetic acid derivatives
GB0902648D0 (en) 2009-02-17 2009-04-01 Argenta Discovery Ltd Pharmaceutical compounds and compositions

Also Published As

Publication number Publication date
ZA201105993B (en) 2012-10-31
CN103483338A (zh) 2014-01-01
IL214658A0 (en) 2011-09-27
TN2011000380A1 (en) 2013-03-27
SG174134A1 (en) 2011-10-28
JP2012517992A (ja) 2012-08-09
US20120088763A1 (en) 2012-04-12
PE20120655A1 (es) 2012-06-07
MX2011008496A (es) 2011-11-18
EP2398798A1 (en) 2011-12-28
CA2752693A1 (en) 2010-08-26
CN102395586A (zh) 2012-03-28
KR20110116030A (ko) 2011-10-24
AU2010215261A1 (en) 2011-09-08
CL2011001977A1 (es) 2011-11-18
WO2010094956A1 (en) 2010-08-26
EA201190119A1 (ru) 2012-05-30
US8557797B2 (en) 2013-10-15
MA33128B1 (fr) 2012-03-01
CO6420344A2 (es) 2012-04-16

Similar Documents

Publication Publication Date Title
FR25C1006I2 (fr) Inhibiteurs de pyrazolyl-quinoxaline kinase
CY2019027I2 (el) Παραγωγα φωσφορου ως αναστολεις κινασης
BRPI0913580A2 (pt) pirrolopiridinas como inibidores de quinase
ES2598358T8 (es) Derivados de quinolina como inhibidores de PI3K quinasa
BRPI0913879A2 (pt) fenilpirazinonas como inibidores de quinase
BRPI0920135A2 (pt) imidazopiridazinacarbonitrilos úteis como inibidores de quinase
BRPI0922962A2 (pt) inibidores de p38 map quinase
BRPI1014572A2 (pt) imidazoprazinas para uso como inibidores de cinase
EP2498607A4 (en) Kinase Inhibitors
EP2493313A4 (en) Kinase Inhibitors
DK2350047T3 (da) p38-MAP-KINASEINHIBITORER
BR112012029405A2 (pt) compostos macrocíclicos como inibidores de trk quinase
ZA201105993B (en) Triazolopyridine derivatives as p38 map kinase inhibitors
EP2558099A4 (en) Kinase inhibitors
CO6831983A2 (es) Compuestos heterocíclicos como inhibidores de cinasas
BRPI0908849A2 (pt) Composto e composições como c-kit e inibidores de pdgfr quinase
EP2632898A4 (en) HETEROCYCLIC TYROSINE KINASE HEMMER
BR112013008527A2 (pt) derivados de pirazolo-quinazolina substituídos como inibidores de cinase
CO6900140A2 (es) Compuestos y composiciones como inhibidores de la quinasa c-kit
CO6900141A2 (es) Compuestos y composiciones como inhibidores de la quinasa c-kit
BRPI0811434A2 (pt) imidazopiridazinas como inibidores de pi3k lipídeo cinase.
EP2519517A4 (en) TYPE II RAF KINASE INHIBITORS
BRPI0811516A2 (pt) Compostos e composições como inibidores de c-kit e pdgfr cinase
BRPI0811065A2 (pt) Indazóis 5-heteroaril substituídos como inibidores de quinase
CO6880068A2 (es) Aminoquinazolinas como inhibidores de quinasa

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.