BRPI1006602A2 - composto, método para modular um receptor de histamina em um indivíduo, composição farmacêutica, kit e método para tratar um distúrbio cognitivo ou um distúrbio induzido por pelo menos um sintoma associado com a alteração da cognição - Google Patents

composto, método para modular um receptor de histamina em um indivíduo, composição farmacêutica, kit e método para tratar um distúrbio cognitivo ou um distúrbio induzido por pelo menos um sintoma associado com a alteração da cognição

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Publication number
BRPI1006602A2
BRPI1006602A2 BRPI1006602A BRPI1006602A BRPI1006602A2 BR PI1006602 A2 BRPI1006602 A2 BR PI1006602A2 BR PI1006602 A BRPI1006602 A BR PI1006602A BR PI1006602 A BRPI1006602 A BR PI1006602A BR PI1006602 A2 BRPI1006602 A2 BR PI1006602A2
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BR
Brazil
Prior art keywords
disorder
cognitive
compound
kit
individual
Prior art date
Application number
BRPI1006602A
Other languages
English (en)
Inventor
Parasmal Jain Rajendra
Chakravarty Sarvajit
Original Assignee
Medivation Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivation Technologies Inc filed Critical Medivation Technologies Inc
Publication of BRPI1006602A2 publication Critical patent/BRPI1006602A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

composto, uso de um composto, composição farmacêutica e kit são descri.tos os novos compostos heterocíclicos que podem ser usados para modular um receptor de histamina em um indivíduo. são descritos pirido[4,3-b]indóis, já que são composições farmacêuticas que abrangem os compostos e os métodos de uso dos compostos em uma variedade de aplicações terapêuticas, incluindo o tratamento de um distúrbio cognitivo, distúrbio psicótico, distúrbio mediado por neurotransmissor e/ou um distúrbio neuronal.
BRPI1006602A 2009-04-29 2010-04-29 composto, método para modular um receptor de histamina em um indivíduo, composição farmacêutica, kit e método para tratar um distúrbio cognitivo ou um distúrbio induzido por pelo menos um sintoma associado com a alteração da cognição BRPI1006602A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1136MU2009 2009-04-29
US18126209P 2009-05-26 2009-05-26
PCT/US2010/033053 WO2010127177A1 (en) 2009-04-29 2010-04-29 Pyrido [4,3-b] indoles and methods of use

Publications (1)

Publication Number Publication Date
BRPI1006602A2 true BRPI1006602A2 (pt) 2019-01-15

Family

ID=43032567

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1006602A BRPI1006602A2 (pt) 2009-04-29 2010-04-29 composto, método para modular um receptor de histamina em um indivíduo, composição farmacêutica, kit e método para tratar um distúrbio cognitivo ou um distúrbio induzido por pelo menos um sintoma associado com a alteração da cognição

Country Status (8)

Country Link
US (2) US9255094B2 (pt)
EP (1) EP2424364A4 (pt)
JP (1) JP5711725B2 (pt)
CN (1) CN102480955B (pt)
AU (1) AU2010242910B2 (pt)
BR (1) BRPI1006602A2 (pt)
CA (1) CA2760541A1 (pt)
WO (1) WO2010127177A1 (pt)

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JP5711725B2 (ja) 2015-05-07
US9255094B2 (en) 2016-02-09
JP2012525430A (ja) 2012-10-22
AU2010242910A1 (en) 2011-11-17
CN102480955A (zh) 2012-05-30
US20130190328A1 (en) 2013-07-25
EP2424364A1 (en) 2012-03-07
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CA2760541A1 (en) 2010-11-04
CN102480955B (zh) 2015-08-05

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