BRPI1006733A2 - kit para formação de imagem médica marcada e/ou produtos terapêuticos, agente de pré-marcação, sonda de formação de imagem, sonda terapêutica e método - Google Patents
kit para formação de imagem médica marcada e/ou produtos terapêuticos, agente de pré-marcação, sonda de formação de imagem, sonda terapêutica e métodoInfo
- Publication number
- BRPI1006733A2 BRPI1006733A2 BRPI1006733A BRPI1006733A BRPI1006733A2 BR PI1006733 A2 BRPI1006733 A2 BR PI1006733A2 BR PI1006733 A BRPI1006733 A BR PI1006733A BR PI1006733 A BRPI1006733 A BR PI1006733A BR PI1006733 A2 BRPI1006733 A2 BR PI1006733A2
- Authority
- BR
- Brazil
- Prior art keywords
- probe
- therapeutic
- imaging
- marking agent
- kit
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
- A61K47/6897—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0495—Pretargeting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09158059 | 2009-04-16 | ||
| EP09174495 | 2009-10-29 | ||
| PCT/IB2010/051547 WO2010119382A1 (en) | 2009-04-16 | 2010-04-12 | Pretargeting kit, method and agents used therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1006733A2 true BRPI1006733A2 (pt) | 2017-06-13 |
Family
ID=42982159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1006733A BRPI1006733A2 (pt) | 2009-04-16 | 2010-04-12 | kit para formação de imagem médica marcada e/ou produtos terapêuticos, agente de pré-marcação, sonda de formação de imagem, sonda terapêutica e método |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20120039803A1 (pt) |
| EP (1) | EP2419141A1 (pt) |
| CN (1) | CN102438656B (pt) |
| BR (1) | BRPI1006733A2 (pt) |
| RU (1) | RU2011146362A (pt) |
| WO (1) | WO2010119382A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9427482B2 (en) | 2010-12-21 | 2016-08-30 | Koninklijke Philips N.V. | Agents for clearing biomolecules from circulation |
| EP2522369A1 (en) | 2011-05-09 | 2012-11-14 | Koninklijke Philips Electronics N.V. | Pretargeting kit, method and agents used therein |
| JP6215194B2 (ja) | 2011-05-16 | 2017-10-18 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 生体直交型薬物活性化 |
| WO2014081303A1 (en) | 2012-11-22 | 2014-05-30 | Tagworks Pharmaceuticals B.V. | Chemically cleavable group |
| WO2016025480A1 (en) | 2014-08-11 | 2016-02-18 | The General Hospital Corporation | Cyclooctenes for bioorthogonol reactions |
| US20160331852A1 (en) * | 2015-05-11 | 2016-11-17 | Memorial Sloan Kettering Cancer Center | Radioligands for pretargeted pet imaging and methods of their therapeutic use |
| US11617799B2 (en) | 2016-06-27 | 2023-04-04 | Tagworks Pharmaceuticals B.V. | Cleavable tetrazine used in bio-orthogonal drug activation |
| US11560384B2 (en) | 2017-05-04 | 2023-01-24 | University Of Utah Research Foundation | Benzonorbornadiene derivatives and reactions thereof |
| WO2019014549A1 (en) | 2017-07-14 | 2019-01-17 | The Penn State Research Foundation | Compositions and methods for targeted delivery of therapeutic and/or diagnostic species |
| ES2975330T3 (es) | 2018-05-04 | 2024-07-04 | Tagworks Pharmaceuticals B V | Compuestos que comprenden un enlazador para aumentar la estabilidad del trans-cicloocteno |
| US20210299286A1 (en) | 2018-05-04 | 2021-09-30 | Tagworks Pharmaceuticals B.V. | Tetrazines for high click conjugation yield in vivo and high click release yield |
| IL289093B2 (en) | 2019-06-17 | 2025-02-01 | Tagworks Pharmaceuticals B V | Compounds for a fast and efficient "click release" reaction |
| IL289094A (en) | 2019-06-17 | 2022-02-01 | Tagworks Pharmaceuticals B V | Tetrazines for increasing the speed and yield of the "click release" reaction |
| JP2024515104A (ja) | 2021-04-20 | 2024-04-04 | テラパワー, エルエルシー | Ac-225生成のためのチタニアに基づくジェネレータ |
| CN114652857B (zh) * | 2022-03-31 | 2023-10-20 | 成都大学 | 一种用于修复内皮糖萼受损的靶向药物递送系统及其制备方法 |
| CN117700394B (zh) * | 2024-02-06 | 2024-05-28 | 南京大学 | 一类可与非张力烯基硼酸快速环加成反应的四嗪类化合物及其生物医药应用 |
| CN117752824A (zh) * | 2024-02-21 | 2024-03-26 | 中国医学科学院医学实验动物研究所 | 预靶向肿瘤免疫探针、生物正交制剂、试剂盒及应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007039858A2 (en) * | 2005-10-04 | 2007-04-12 | Koninklijke Philips Electronics N.V. | Targeted imaging and/or therapy using the [3+2] azide-alkyne cycloaddition |
| CN102271712B (zh) * | 2008-10-31 | 2015-11-25 | 通用医疗公司 | 用于将物质递送至生物靶标的组合物和方法 |
-
2010
- 2010-04-12 EP EP10717255A patent/EP2419141A1/en not_active Withdrawn
- 2010-04-12 CN CN201080016903.9A patent/CN102438656B/zh not_active Expired - Fee Related
- 2010-04-12 US US13/264,526 patent/US20120039803A1/en not_active Abandoned
- 2010-04-12 BR BRPI1006733A patent/BRPI1006733A2/pt not_active IP Right Cessation
- 2010-04-12 RU RU2011146362/15A patent/RU2011146362A/ru not_active Application Discontinuation
- 2010-04-12 WO PCT/IB2010/051547 patent/WO2010119382A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN102438656A (zh) | 2012-05-02 |
| WO2010119382A1 (en) | 2010-10-21 |
| EP2419141A1 (en) | 2012-02-22 |
| US20120039803A1 (en) | 2012-02-16 |
| RU2011146362A (ru) | 2013-05-27 |
| CN102438656B (zh) | 2014-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 47/00 (2006.01), A61K 51/04 (2006.01), A61K 5 |