BRPI1007011A2 - dispositivo microfluídico funcionalizado para imunofluorescência - Google Patents

dispositivo microfluídico funcionalizado para imunofluorescência

Info

Publication number
BRPI1007011A2
BRPI1007011A2 BRPI1007011A BRPI1007011A BRPI1007011A2 BR PI1007011 A2 BRPI1007011 A2 BR PI1007011A2 BR PI1007011 A BRPI1007011 A BR PI1007011A BR PI1007011 A BRPI1007011 A BR PI1007011A BR PI1007011 A2 BRPI1007011 A2 BR PI1007011A2
Authority
BR
Brazil
Prior art keywords
immunofluorescence
microfluidic device
functionalized microfluidic
functionalized
microfluidic
Prior art date
Application number
BRPI1007011A
Other languages
English (en)
Inventor
Dario Bandiera
Emanuele Barborini
Roberta Carbone
Original Assignee
Tethis S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tethis S P A filed Critical Tethis S P A
Publication of BRPI1007011A2 publication Critical patent/BRPI1007011A2/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • G01N33/5304Reaction vessels, e.g. agglutination plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0822Slides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553Metal or metal coated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI1007011A 2009-01-26 2010-01-26 dispositivo microfluídico funcionalizado para imunofluorescência BRPI1007011A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2009/000465 WO2010083852A1 (en) 2009-01-26 2009-01-26 Functionalized microfluidic device for immunofluorescence
PCT/EP2010/050820 WO2010084196A1 (en) 2009-01-26 2010-01-26 Functionalized microfluidic device for immunofluorescence

Publications (1)

Publication Number Publication Date
BRPI1007011A2 true BRPI1007011A2 (pt) 2016-03-29

Family

ID=40566192

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1007011A BRPI1007011A2 (pt) 2009-01-26 2010-01-26 dispositivo microfluídico funcionalizado para imunofluorescência

Country Status (14)

Country Link
US (1) US9364830B2 (pt)
EP (1) EP2291540B1 (pt)
JP (1) JP5719313B2 (pt)
CN (1) CN102308005B (pt)
BR (1) BRPI1007011A2 (pt)
CA (1) CA2750682C (pt)
DK (1) DK2291540T3 (pt)
ES (1) ES2446277T3 (pt)
HR (1) HRP20140042T1 (pt)
IL (1) IL214238A (pt)
MX (1) MX2011007643A (pt)
PL (1) PL2291540T3 (pt)
PT (1) PT2291540E (pt)
WO (2) WO2010083852A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9995688B2 (en) * 2009-09-21 2018-06-12 Arizona Board Of Regents Use of superhydrophobic surfaces for liquid agglutination assays
WO2012061818A1 (en) * 2010-11-05 2012-05-10 Life Technologies Corporation Flowcells and flowcell reaction chambers
JP6084370B2 (ja) * 2011-05-10 2017-02-22 国立大学法人 東京大学 組織化学用自動反応装置
WO2013125718A1 (ja) * 2012-02-23 2013-08-29 国立大学法人島根大学 マイクロ流路チップ
CN104777101A (zh) * 2015-04-24 2015-07-15 王丹凤 一种观察细胞的方法
IT201600099710A1 (it) * 2016-10-05 2018-04-05 Tethis S P A Portacampioni per analisi di spettrometria di massa in modalità maldi, produzione ed uso del portacampioni
IT201700085439A1 (it) 2017-07-26 2019-01-26 Tethis S P A Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico
KR101952443B1 (ko) * 2018-08-23 2019-02-26 주식회사 아스트로젠 신규한 마그네슘­세리네이트 화합물 및 이의 용도
CN109060688A (zh) * 2018-08-27 2018-12-21 南京采薇且歌信息科技有限公司 一种高精度纳米传感器及其应用
JP7347931B2 (ja) * 2018-12-26 2023-09-20 スリーエム イノベイティブ プロパティズ カンパニー マイクロ流体デバイス用フィルム、マイクロ流体デバイス及びその製造方法
JP7356241B2 (ja) * 2019-03-18 2023-10-04 フコク物産株式会社 マイクロ流体デバイス
TWI762811B (zh) * 2019-08-30 2022-05-01 國立臺灣科技大學 負載有多孔隙奈米顆粒結構之多孔隙基材及其負載製程
CN110553888B (zh) * 2019-09-16 2022-07-12 中国农业科学院特产研究所 一种卵母细胞免疫荧光染色后快速压片的方法
CN110951834A (zh) * 2019-12-10 2020-04-03 中国科学院深圳先进技术研究院 一种基于微流控芯片的细胞荧光原位杂交方法及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0752099A1 (en) * 1994-02-09 1997-01-08 Abbott Laboratories Diagnostic flow cell device
US6613560B1 (en) * 1994-10-19 2003-09-02 Agilent Technologies, Inc. PCR microreactor for amplifying DNA using microquantities of sample fluid
WO1998055651A1 (en) * 1997-06-05 1998-12-10 University Of Massachusetts Method for determining rate of movement of a molecule in a living cell
JP2002531470A (ja) * 1998-12-01 2002-09-24 シントリクス バイオチップ, インコーポレイテッド 支持体表面上で化学反応のアレイを行うための方法および組成物
IT1310029B1 (it) 1999-02-26 2002-02-05 Ist Naz Fisica Della Materia Vaporizzatore a microplasma pulsato.
JP3993372B2 (ja) * 2000-09-13 2007-10-17 独立行政法人理化学研究所 リアクタの製造方法
WO2002030562A1 (en) * 2000-10-10 2002-04-18 Aviva Biosciences Corporation An integrated biochip system for sample preparation and analysis
US20040043479A1 (en) * 2000-12-11 2004-03-04 Briscoe Cynthia G. Multilayerd microfluidic devices for analyte reactions
FR2818287B1 (fr) * 2000-12-14 2003-01-17 Commissariat Energie Atomique Support solide pour l'immobilisation d'oligonucleotides
ES2372007T3 (es) * 2001-02-20 2012-01-12 Vysis, Inc. Métodos y sondas para la detección del cáncer.
WO2004008142A1 (ja) * 2002-07-12 2004-01-22 Mitsubishi Chemical Corporation 分析用チップ、分析用チップユニット、分析装置及びそれを用いた分析方法並びに分析用チップの作製方法
WO2004011672A1 (en) * 2002-07-26 2004-02-05 Ntera Limited Porous nanostructured film sensor
JP4519124B2 (ja) * 2003-01-30 2010-08-04 ユィロス・パテント・アクチボラグ 微小流動性デバイスの内部の壁
FR2872912B1 (fr) * 2004-07-09 2007-03-02 Centre Nat Rech Scient Cnrse Nouveau systeme microfluidique et procede de capture de cellules
WO2007009994A1 (en) * 2005-07-21 2007-01-25 Tethis S.R.L. Support having nanostructured titanium dioxide film and uses thereof
WO2007085911A2 (en) * 2005-12-19 2007-08-02 National Center For Scientific Research Demokritos Modified nanostructured titania materials and methods of manufacture
US7695956B2 (en) * 2006-01-12 2010-04-13 Biocept, Inc. Device for cell separation and analysis and method of using
CA2663286A1 (en) * 2006-09-15 2008-03-20 The Governors Of The University Of Alberta Automatedfishanalysis,circulating microfluidic chip, and method for immobilizing cells to a microfluidic chip

Also Published As

Publication number Publication date
WO2010084196A1 (en) 2010-07-29
CN102308005A (zh) 2012-01-04
DK2291540T3 (en) 2014-02-17
HK1154637A1 (en) 2012-04-27
WO2010083852A1 (en) 2010-07-29
JP5719313B2 (ja) 2015-05-13
CA2750682C (en) 2016-10-25
AU2010207677A1 (en) 2011-09-08
PT2291540E (pt) 2014-03-03
IL214238A0 (en) 2011-09-27
EP2291540A1 (en) 2011-03-09
IL214238A (en) 2017-11-30
CA2750682A1 (en) 2010-07-29
ES2446277T3 (es) 2014-03-06
EP2291540B1 (en) 2013-11-20
PL2291540T3 (pl) 2014-05-30
MX2011007643A (es) 2011-10-28
HRP20140042T1 (hr) 2014-02-28
JP2012515908A (ja) 2012-07-12
US9364830B2 (en) 2016-06-14
AU2010207677A2 (en) 2011-09-08
CN102308005B (zh) 2015-07-15
US20110281267A1 (en) 2011-11-17

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2498 DE 21-11-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.