BRPI1007476A2 - análogos de ciclosporina para prevenir ou tratar infecção por hepatite c - Google Patents

análogos de ciclosporina para prevenir ou tratar infecção por hepatite c

Info

Publication number: BRPI1007476A2
Authority: BR; Brazil
Prior art keywords: infection; prevent; treat hepatitis; cyclosporine analogues; cyclosporine
Prior art date: 2009-01-30

Application number

BRPI1007476A

Other languages

English (en)

Inventor

Jiang Long

Quoqiang Wang

Xuri Gao

Yat Sun Or

Original Assignee

Enanta Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-01-30

Filing date

2010-01-30

Publication date

2016-02-16

2010-01-30 Application filed by Enanta Pharm Inc filed Critical Enanta Pharm Inc

2016-02-16 Publication of BRPI1007476A2 publication Critical patent/BRPI1007476A2/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
208000005176 Hepatitis C Diseases 0.000 title 1
208000010710 hepatitis C virus infection Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Zoology (AREA)
AIDS & HIV (AREA)
Biotechnology (AREA)
Tropical Medicine & Parasitology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

BRPI1007476A 2009-01-30 2010-01-30 análogos de ciclosporina para prevenir ou tratar infecção por hepatite c BRPI1007476A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14858309P	2009-01-30	2009-01-30
PCT/US2010/022675 WO2010088573A1 (en)	2009-01-30	2010-01-30	Cyclosporin analogues for preventing or treating hepatitis c infection

Publications (1)

Publication Number	Publication Date
BRPI1007476A2 true BRPI1007476A2 (pt)	2016-02-16

Family

ID=42396050

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1007476A BRPI1007476A2 (pt)	2009-01-30	2010-01-30	análogos de ciclosporina para prevenir ou tratar infecção por hepatite c

Country Status (14)

Country	Link
US (3)	US8367618B2 (pt)
EP (1)	EP2391376A4 (pt)
JP (1)	JP5406943B2 (pt)
KR (2)	KR20110111321A (pt)
CN (1)	CN102365094A (pt)
AU (1)	AU2010208071C1 (pt)
BR (1)	BRPI1007476A2 (pt)
CA (1)	CA2751210C (pt)
IL (1)	IL214278A0 (pt)
MX (1)	MX2011008000A (pt)
NZ (1)	NZ594755A (pt)
RU (1)	RU2492181C2 (pt)
SG (1)	SG173180A1 (pt)
WO (1)	WO2010088573A1 (pt)

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US9890198B2 (en) *	2010-12-03	2018-02-13	S&T Global Inc.	Cyclosporin derivatives and uses thereof
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CN105693820A (zh) *	2014-11-27	2016-06-22	武汉药明康德新药开发有限公司	一种降解环孢菌素a的方法
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TW201629069A (zh)	2015-01-09	2016-08-16	霍普驅動生物科技股份有限公司	參與協同結合之化合物及其用途
EP3247378B8 (en)	2015-01-09	2023-08-23	Revolution Medicines, Inc.	Macrocyclic compounds that participate in cooperative binding and medical uses thereof
EP4242304A3 (en)	2015-10-01	2024-02-07	Revolution Medicines, Inc.	Methods and reagents for analyzing protein-protein interfaces
CN109641062A (zh)	2016-04-12	2019-04-16	华普卓威生物公司	用于产生化合物的组合物和方法
US11479797B2 (en)	2016-10-28	2022-10-25	Ginkgo Bioworks, Inc.	Compositions and methods for the production of compounds
AU2020377925A1 (en)	2019-11-04	2022-05-05	Revolution Medicines, Inc.	Ras inhibitors
IL322454A (en)	2019-11-04	2025-09-01	Revolution Medicines Inc	ras inhibitors
TW202132316A (zh)	2019-11-04	2021-09-01	美商銳新醫藥公司	Ｒａｓ抑制劑
IL296586B1 (en) *	2020-03-26	2026-04-01	Farsight Medical Tech Shanghai Co Ltd	Cyclophilin inhibitors and their uses
CA3194067A1 (en)	2020-09-15	2022-03-24	Revolution Medicines, Inc.	Ras inhibitors
KR20240017811A (ko)	2021-05-05	2024-02-08	레볼루션 메디슨즈, 인크.	암의 치료를 위한 ras 억제제
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2010
- 2010-01-30 KR KR1020117020221A patent/KR20110111321A/ko not_active Ceased
- 2010-01-30 MX MX2011008000A patent/MX2011008000A/es active IP Right Grant
- 2010-01-30 RU RU2011133900/04A patent/RU2492181C2/ru not_active IP Right Cessation
- 2010-01-30 CA CA2751210A patent/CA2751210C/en not_active Expired - Fee Related
- 2010-01-30 NZ NZ594755A patent/NZ594755A/en not_active IP Right Cessation
- 2010-01-30 EP EP10736507A patent/EP2391376A4/en not_active Withdrawn
- 2010-01-30 CN CN2010800142248A patent/CN102365094A/zh active Pending
- 2010-01-30 JP JP2011548361A patent/JP5406943B2/ja not_active Expired - Fee Related
- 2010-01-30 US US12/697,215 patent/US8367618B2/en not_active Expired - Fee Related
- 2010-01-30 WO PCT/US2010/022675 patent/WO2010088573A1/en not_active Ceased
- 2010-01-30 BR BRPI1007476A patent/BRPI1007476A2/pt not_active Application Discontinuation
- 2010-01-30 AU AU2010208071A patent/AU2010208071C1/en not_active Ceased
- 2010-01-30 SG SG2011054715A patent/SG173180A1/en unknown
- 2010-01-30 KR KR1020147001832A patent/KR101476626B1/ko not_active Expired - Fee Related
2011
- 2011-07-25 IL IL214278A patent/IL214278A0/en unknown
2013
- 2013-01-04 US US13/734,074 patent/US9156886B2/en active Active
2015
- 2015-09-02 US US14/843,119 patent/US9603895B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU2010208071C1 (en)	2013-06-20
US20100196316A1 (en)	2010-08-05
US20130183267A1 (en)	2013-07-18
RU2011133900A (ru)	2013-03-10
IL214278A0 (en)	2011-09-27
EP2391376A1 (en)	2011-12-07
US9603895B2 (en)	2017-03-28
NZ594755A (en)	2013-12-20
CA2751210A1 (en)	2010-08-05
EP2391376A4 (en)	2012-08-01
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