BRPI1007476A2 - análogos de ciclosporina para prevenir ou tratar infecção por hepatite c - Google Patents

análogos de ciclosporina para prevenir ou tratar infecção por hepatite c

Info

Publication number: BRPI1007476A2
Authority: BR; Brazil
Prior art keywords: infection; prevent; treat hepatitis; cyclosporine analogues; cyclosporine
Prior art date: 2009-01-30

Application number

BRPI1007476A

Other languages

English (en)

Inventor

Jiang Long

Quoqiang Wang

Xuri Gao

Yat Sun Or

Original Assignee

Enanta Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-01-30

Filing date

2010-01-30

Publication date

2016-02-16

2010-01-30 Application filed by Enanta Pharm Inc filed Critical Enanta Pharm Inc

2016-02-16 Publication of BRPI1007476A2 publication Critical patent/BRPI1007476A2/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
208000005176 Hepatitis C Diseases 0.000 title 1
208000010710 hepatitis C virus infection Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biotechnology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

BRPI1007476A 2009-01-30 2010-01-30 análogos de ciclosporina para prevenir ou tratar infecção por hepatite c BRPI1007476A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14858309P	2009-01-30	2009-01-30
PCT/US2010/022675 WO2010088573A1 (en)	2009-01-30	2010-01-30	Cyclosporin analogues for preventing or treating hepatitis c infection

Publications (1)

Publication Number	Publication Date
BRPI1007476A2 true BRPI1007476A2 (pt)	2016-02-16

Family

ID=42396050

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1007476A BRPI1007476A2 (pt)	2009-01-30	2010-01-30	análogos de ciclosporina para prevenir ou tratar infecção por hepatite c

Country Status (14)

Country	Link
US (3)	US8367618B2 (pt)
EP (1)	EP2391376A4 (pt)
JP (1)	JP5406943B2 (pt)
KR (2)	KR20110111321A (pt)
CN (1)	CN102365094A (pt)
AU (1)	AU2010208071C1 (pt)
BR (1)	BRPI1007476A2 (pt)
CA (1)	CA2751210C (pt)
IL (1)	IL214278A0 (pt)
MX (1)	MX2011008000A (pt)
NZ (1)	NZ594755A (pt)
RU (1)	RU2492181C2 (pt)
SG (1)	SG173180A1 (pt)
WO (1)	WO2010088573A1 (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG173180A1 (en) *	2009-01-30	2011-09-29	Enanta Pharm Inc	Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en) *	2009-02-19	2013-07-09	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US8349312B2 (en) *	2009-07-09	2013-01-08	Enanta Pharmaceuticals, Inc.	Proline substituted cyclosporin analogues
US8367053B2 (en) *	2009-07-09	2013-02-05	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US8685917B2 (en) *	2009-07-09	2014-04-01	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
AU2010339460A1 (en) *	2009-12-30	2012-07-19	Scynexis Inc.	Cyclosporine analogues
US8623814B2 (en) *	2010-02-23	2014-01-07	Enanta Pharmaceuticals, Inc.	Antiviral agents
WO2012009715A2 (en)	2010-07-16	2012-01-19	S&T Global Inc.	Novel cyclosporin derivatives for the treatment and prevention of a viral infection
WO2012021796A2 (en) *	2010-08-12	2012-02-16	S&T Global, Inc.	Novel cyclosporin derivatives for the treatment and prevention of a viral infection
US9890198B2 (en)	2010-12-03	2018-02-13	S&T Global Inc.	Cyclosporin derivatives and uses thereof
JP6093307B2 (ja) *	2010-12-03	2017-03-08	エスアンドティーグローバルインク．	ウイルス感染の治療および予防のための新規シクロスポリン誘導体
JP6144627B2 (ja)	2010-12-15	2017-06-07	コントラヴィアファーマシューティカルズ、インク．	アミノ酸１および３で修飾されたシクロスポリン類似体分子
US9428845B1 (en)	2010-12-28	2016-08-30	Warp Drive Bio, Inc.	Identifying new therapeutic agents
AR090964A1 (es) *	2012-05-09	2014-12-17	Novartis Ag	Proceso para la elaboracion de undecapeptidos ciclicos
EP2855508B1 (en)	2012-06-01	2018-02-14	Allergan, Inc.	Cyclosporin a analogs
WO2014049540A2 (en) *	2012-09-29	2014-04-03	Novartis Ag	Cyclic peptides and use as medicines
US8906853B2 (en)	2012-11-28	2014-12-09	Enanta Pharmaceuticals, Inc.	[N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
SG11201601274QA (en) *	2013-08-26	2016-03-30	Enanta Pharm Inc	Cyclosporin analogues for preventing or treating hepatitis c
JP6413455B2 (ja) *	2014-08-07	2018-10-31	日本電気株式会社	給湯機制御装置、給湯機制御システム、給湯機制御方法およびプログラム
GB201414806D0 (en)	2014-08-20	2014-10-01	Ucl Business Plc	Cyclosporin conjugates
WO2016073480A1 (en) *	2014-11-03	2016-05-12	Enanta Pharmaceuticals, Inc.	Novel cyclosporin analogues for preventing or treating hepatitis c infection
CN105693820A (zh) *	2014-11-27	2016-06-22	武汉药明康德新药开发有限公司	一种降解环孢菌素a的方法
WO2016112321A1 (en)	2015-01-08	2016-07-14	Allergan, Inc.	Cyclosporin derivatives wherein the mebmt sidechain has been cyclized
EP4289950A3 (en)	2015-01-09	2024-01-24	Revolution Medicines, Inc.	Macrocyclic compounds that participate in cooperative binding and medical uses thereof
TW201629069A (zh)	2015-01-09	2016-08-16	霍普驅動生物科技股份有限公司	參與協同結合之化合物及其用途
EP3355930A4 (en)	2015-10-01	2019-03-06	Warp Drive Bio, Inc.	METHOD AND REAGENTS FOR THE ANALYSIS OF PROTEIN-PROTEIN INTERFACES
KR102359972B1 (ko)	2016-04-12	2022-02-10	징코 바이오웍스, 인크.	화합물의 제조를 위한 조성물 및 방법
WO2018081592A2 (en)	2016-10-28	2018-05-03	Warp Drive Bio, Inc.	Compositions and methods for the production of compounds
PE20221277A1 (es)	2019-11-04	2022-09-05	Revolution Medicines Inc	Inhibidores de ras
CN114867735A (zh)	2019-11-04	2022-08-05	锐新医药公司	Ras抑制剂
CN114786777A (zh)	2019-11-04	2022-07-22	锐新医药公司	Ras抑制剂
IL296586B1 (en) *	2020-03-26	2026-04-01	Farsight Medical Tech Shanghai Co Ltd	Cyclophilin inhibitors and their uses
AU2021345111B2 (en)	2020-09-15	2025-11-27	Revolution Medicines, Inc.	Indole derivatives as Ras inhibitors in the treatment of cancer
CR20230558A (es)	2021-05-05	2024-01-24	Revolution Medicines Inc	Inhibidores de ras para el tratamiento del cáncer
AR127308A1 (es)	2021-10-08	2024-01-10	Revolution Medicines Inc	Inhibidores ras

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH614931A5 (pt) *	1975-11-04	1979-12-28	Sandoz Ag
DE2819094A1 (de) *	1977-05-10	1978-11-23	Sandoz Ag	Cyclosporin-derivate, ihre verwendung und herstellung
SE448386B (sv) *	1978-10-18	1987-02-16	Sandoz Ag	Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem
EP0034567B1 (en)	1980-02-14	1984-11-07	Sandoz Ag	A method for the total synthesis of cyclosporins and novel cyclosporins
US4396542A (en) *	1980-02-14	1983-08-02	Sandoz Ltd.	Method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production
DE3260468D1 (en)	1981-01-09	1984-09-06	Sandoz Ag	Novel cyclosporins
CY1915A (en)	1984-10-04	1985-09-27	Sandoz Ag	Cyclosporins
EP0194972B1 (en) *	1985-03-11	1992-07-29	Sandoz Ag	Novel cyclosporins
US5239057A (en) *	1987-03-27	1993-08-24	Abbott Laboratories	Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US4798823A (en) *	1987-06-03	1989-01-17	Merck & Co., Inc.	New cyclosporin analogs with modified "C-9 amino acids"
ES2059558T3 (es) *	1987-06-17	1994-11-16	Sandoz Ag	Ciclosporins y su uso como productos farmaceuticos.
GB2206119B (en)	1987-06-22	1990-10-31	Merck & Co Inc	A new cyclosporin derivative with modified "8-amino acid"
GB8717299D0 (en)	1987-07-22	1987-08-26	Nat Res Dev	Peptides
GB8717300D0 (en)	1987-07-22	1987-08-26	Nat Res Dev	Cyclosporins
GB2207678A (en)	1987-08-03	1989-02-08	Merck & Co Inc	Novel immunosuppressive fluorinated cyclosporin analogs
US5604092A (en) *	1988-12-05	1997-02-18	The Trustees Of Columbia University In The City Of New York	Method for the detection of HIV-1 using a cyclosporine-specific monoclonal antibody that reacts with the P24 Gag protein
US5284826A (en) *	1989-07-24	1994-02-08	Sandoz Ltd.	0-hydroxyethyl and acyloxyethyl derivatives of [ser]8 cyclosporins
FR2762843B1 (fr)	1997-04-30	1999-12-10	Rhone Poulenc Rorer Sa	Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
AU750245B2 (en)	1997-10-08	2002-07-11	Aurinia Phamaceuticals Inc.	Deuterated cyclosporine analogs and their use as immunomodulating agents
PT1091975E (pt) *	1998-07-01	2006-05-31	Debiopharm Sa	Nova ciclosporina com um perfil de actividade melhorado
US6784156B2 (en) *	2001-03-05	2004-08-31	Enanta Pharmaceuticals, Inc.	Cyclosporins for the treatment of respiratory diseases
US20030087813A1 (en) *	2001-10-12	2003-05-08	Or Yat Sun	Cyclosporin analogs for the treatment of lung diseases
US6809077B2 (en) *	2001-10-12	2004-10-26	Enanta Pharmaceuticals, Inc.	Cyclosporin analogs for the treatment of autoimmune diseases
WO2003033526A2 (en)	2001-10-19	2003-04-24	Isotechnika Inc.	Synthesis of cyclosporin analogs
US7012065B2 (en) *	2003-02-07	2006-03-14	Enanta Pharmaceuticals, Inc.	Cyclosporins for the treatment of immune disorders
US20040266669A1 (en) *	2003-06-20	2004-12-30	Wu Frank X. H.	Cyclosporin derivatives for the treatment of immune disorders
GB0320638D0 (en)	2003-09-03	2003-10-01	Novartis Ag	Organic compounds
BRPI0513370A (pt)	2004-07-14	2008-05-06	Novartis Ag	uso de uma combinação de ciclosporina e interferonas peguilados para tratamento de hepatite c (hcv)
EP1804823A4 (en)	2004-09-29	2010-06-09	Amr Technology Inc	NEW CYCLOSPORIN ANALOGUE AND ITS PHARMACEUTICAL APPLICATIONS
JP5139065B2 (ja)	2004-10-01	2013-02-06	スシネキスインク	Ｃ型肝炎感染の治療及び予防のための３−エーテル及び３−チオエーテル置換シクロスポリン誘導体
UA88484C2 (ru)	2004-10-01	2009-10-26	Дебиофарм Са	ПРИМЕНЕНИЕ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИНА ДЛЯ ЛЕЧЕНИЯ ИНФЕКЦИИ ГЕПАТИТА С И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ВКЛЮЧАЕТ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИН
US8329658B2 (en)	2005-09-30	2012-12-11	Scynexis, Inc.	Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
CA2623898C (en) *	2005-10-26	2013-12-24	Astellas Pharma Inc.	New cyclic peptide compounds
JP2009529059A (ja) *	2006-03-08	2009-08-13	アキリオンファーマシューティカルズ，インコーポレーテッド	抗ｃ型肝炎ウイルス活性を有する置換アミノチアゾール誘導体
US7696166B2 (en)	2006-03-28	2010-04-13	Albany Molecular Research, Inc.	Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US20070232532A1 (en)	2006-03-28	2007-10-04	Amr Technology, Inc.	Use of cyclosporin alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en)	2006-03-28	2010-04-13	Albany Molecular Research, Inc.	Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7776832B2 (en) *	2006-04-21	2010-08-17	Gem Pharmaceuticals, Llc	Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines
ES2396170T3 (es) *	2007-05-02	2013-02-19	Astellas Pharma Inc.	Nuevos compuestos péptídicos ciclicos
WO2008143996A1 (en) *	2007-05-18	2008-11-27	Scynexis, Inc.	New chemical processes
SG173180A1 (en) *	2009-01-30	2011-09-29	Enanta Pharm Inc	Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en)	2009-02-19	2013-07-09	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US8685917B2 (en) *	2009-07-09	2014-04-01	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US8367053B2 (en)	2009-07-09	2013-02-05	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US8349312B2 (en) *	2009-07-09	2013-01-08	Enanta Pharmaceuticals, Inc.	Proline substituted cyclosporin analogues
US8429835B2 (en) *	2009-10-21	2013-04-30	Nike, Inc.	Composite shoe upper and method of making same
US8623814B2 (en) *	2010-02-23	2014-01-07	Enanta Pharmaceuticals, Inc.	Antiviral agents
US8178531B2 (en) *	2010-02-23	2012-05-15	Enanta Pharmaceuticals, Inc.	Antiviral agents
WO2012009715A2 (en)	2010-07-16	2012-01-19	S&T Global Inc.	Novel cyclosporin derivatives for the treatment and prevention of a viral infection
WO2012021796A2 (en)	2010-08-12	2012-02-16	S&T Global, Inc.	Novel cyclosporin derivatives for the treatment and prevention of a viral infection
SG11201601274QA (en) *	2013-08-26	2016-03-30	Enanta Pharm Inc	Cyclosporin analogues for preventing or treating hepatitis c

2010
- 2010-01-30 SG SG2011054715A patent/SG173180A1/en unknown
- 2010-01-30 KR KR1020117020221A patent/KR20110111321A/ko not_active Ceased
- 2010-01-30 BR BRPI1007476A patent/BRPI1007476A2/pt not_active Application Discontinuation
- 2010-01-30 US US12/697,215 patent/US8367618B2/en not_active Expired - Fee Related
- 2010-01-30 KR KR1020147001832A patent/KR101476626B1/ko not_active Expired - Fee Related
- 2010-01-30 EP EP10736507A patent/EP2391376A4/en not_active Withdrawn
- 2010-01-30 WO PCT/US2010/022675 patent/WO2010088573A1/en not_active Ceased
- 2010-01-30 RU RU2011133900/04A patent/RU2492181C2/ru not_active IP Right Cessation
- 2010-01-30 AU AU2010208071A patent/AU2010208071C1/en not_active Ceased
- 2010-01-30 MX MX2011008000A patent/MX2011008000A/es active IP Right Grant
- 2010-01-30 CA CA2751210A patent/CA2751210C/en not_active Expired - Fee Related
- 2010-01-30 JP JP2011548361A patent/JP5406943B2/ja not_active Expired - Fee Related
- 2010-01-30 NZ NZ594755A patent/NZ594755A/en not_active IP Right Cessation
- 2010-01-30 CN CN2010800142248A patent/CN102365094A/zh active Pending
2011
- 2011-07-25 IL IL214278A patent/IL214278A0/en unknown
2013
- 2013-01-04 US US13/734,074 patent/US9156886B2/en active Active
2015
- 2015-09-02 US US14/843,119 patent/US9603895B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2010088573A1 (en)	2010-08-05
AU2010208071B2 (en)	2012-11-08
US20100196316A1 (en)	2010-08-05
US8367618B2 (en)	2013-02-05
KR20110111321A (ko)	2011-10-10
US20130183267A1 (en)	2013-07-18
JP5406943B2 (ja)	2014-02-05
KR20140014323A (ko)	2014-02-05
RU2492181C2 (ru)	2013-09-10
MX2011008000A (es)	2011-09-15
CA2751210C (en)	2015-04-21
US20160051625A1 (en)	2016-02-25
AU2010208071A1 (en)	2011-09-01
KR101476626B1 (ko)	2014-12-26
EP2391376A4 (en)	2012-08-01
EP2391376A1 (en)	2011-12-07
US9156886B2 (en)	2015-10-13
NZ594755A (en)	2013-12-20
RU2011133900A (ru)	2013-03-10
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