BRPI1007625A2 - sistema microfluídico, dispositivo e método para misturar fluídos - Google Patents

sistema microfluídico, dispositivo e método para misturar fluídos

Info

Publication number
BRPI1007625A2
BRPI1007625A2 BRPI1007625A BRPI1007625A BRPI1007625A2 BR PI1007625 A2 BRPI1007625 A2 BR PI1007625A2 BR PI1007625 A BRPI1007625 A BR PI1007625A BR PI1007625 A BRPI1007625 A BR PI1007625A BR PI1007625 A2 BRPI1007625 A2 BR PI1007625A2
Authority
BR
Brazil
Prior art keywords
microfluidic system
mixing fluids
fluids
mixing
microfluidic
Prior art date
Application number
BRPI1007625A
Other languages
English (en)
Inventor
H Bouma Peter
Wimberger-Friedl Reinhold
C De Gier Ronald
Original Assignee
Koninl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninl Philips Electronics Nv filed Critical Koninl Philips Electronics Nv
Publication of BRPI1007625A2 publication Critical patent/BRPI1007625A2/pt
Publication of BRPI1007625B1 publication Critical patent/BRPI1007625B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3017—Mixing chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/451—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4521—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through orifices in elements, e.g. flat plates or cylinders, which obstruct the whole diameter of the tube
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/65—Mixers with shaking, oscillating, or vibrating mechanisms the materials to be mixed being directly submitted to a pulsating movement, e.g. by means of an oscillating piston or air column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3045—Micromixers using turbulence on microscale
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Accessories For Mixers (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
BRPI1007625-5A 2009-04-23 2010-04-16 Sistema microfluídico para misturar um fluido, cartucho, e método para misturar fluidos BRPI1007625B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09158646.1 2009-04-23
EP09158646 2009-04-23
PCT/IB2010/051671 WO2010122464A1 (en) 2009-04-23 2010-04-16 Mixer with zero dead volume and method for mixing

Publications (2)

Publication Number Publication Date
BRPI1007625A2 true BRPI1007625A2 (pt) 2017-01-31
BRPI1007625B1 BRPI1007625B1 (pt) 2020-03-10

Family

ID=42317061

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1007625-5A BRPI1007625B1 (pt) 2009-04-23 2010-04-16 Sistema microfluídico para misturar um fluido, cartucho, e método para misturar fluidos

Country Status (8)

Country Link
US (1) US9174182B2 (pt)
EP (1) EP2421636B1 (pt)
JP (1) JP5551763B2 (pt)
KR (1) KR101677751B1 (pt)
CN (2) CN105921066B (pt)
BR (1) BRPI1007625B1 (pt)
RU (1) RU2554573C2 (pt)
WO (1) WO2010122464A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2799137A1 (en) 2013-04-30 2014-11-05 Koninklijke Philips N.V. Fluidic system for processing a sample fluid
DE102014200499B4 (de) 2014-01-14 2017-03-30 Robert Bosch Gmbh Mikrofluidisches System sowie Vorrichtung und Verfahren zum Leiten von Fluid in einem mikrofluidischen System
EP3222351A1 (en) * 2016-03-23 2017-09-27 Ecole Polytechnique Fédérale de Lausanne (EPFL) Microfluidic network device
WO2020027751A2 (en) * 2018-03-09 2020-02-06 Ihsan Dogramaci Bilkent Universitesi Hydraulic interface apparatus and operation method for microfluidic systems
AT523841B1 (de) * 2020-10-19 2021-12-15 Omicron Electronics Gmbh Vorrichtung und Verfahren zum Entgasen einer Einrichtung und entsprechendes Prüfsystem zur Gasanalyse
WO2022159098A1 (en) * 2021-01-22 2022-07-28 Hewlett-Packard Development Company, L.P. In place fluid mixing within microfluidic device chamber
TWI757167B (zh) * 2021-05-04 2022-03-01 國立清華大學 擾流穩定晶片、液滴生成系統及液滴製備方法
US12186748B2 (en) 2022-06-24 2025-01-07 Hewlett-Packard Development Company, L.P. Self-priming microfluidic structures

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932220A (en) 1970-08-11 1976-01-13 Liotta Lance A Method for isolating bacterial colonies
US5356814A (en) 1992-09-29 1994-10-18 Hoffmann-La Roche Inc. Disaggregation device for cytological specimens
US5595712A (en) * 1994-07-25 1997-01-21 E. I. Du Pont De Nemours And Company Chemical mixing and reaction apparatus
US6239906B1 (en) 1997-09-04 2001-05-29 Andrew E. Lorincz Flexible microscope slide
SE9800070D0 (sv) 1998-01-14 1998-01-14 Hemocue Ab Blandningsmetod
US6180314B1 (en) 1998-05-27 2001-01-30 Becton, Dickinson And Company Method for preparing thin liquid samples for microscopic analysis
US6591852B1 (en) 1998-10-13 2003-07-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
FR2803225B1 (fr) 1999-12-29 2002-06-14 Biomerieux Sa Appareil d'analyse a compartiment reactionnel a geometrie variable, procede de mixage et de guidage de liquides
US6890093B2 (en) 2000-08-07 2005-05-10 Nanostream, Inc. Multi-stream microfludic mixers
US7258774B2 (en) 2000-10-03 2007-08-21 California Institute Of Technology Microfluidic devices and methods of use
GB0028647D0 (en) 2000-11-24 2001-01-10 Nextgen Sciences Ltd Apparatus for chemical assays
US7223363B2 (en) 2001-03-09 2007-05-29 Biomicro Systems, Inc. Method and system for microfluidic interfacing to arrays
US20030064507A1 (en) 2001-07-26 2003-04-03 Sean Gallagher System and methods for mixing within a microfluidic device
US6660527B2 (en) 2002-03-28 2003-12-09 David Karl Stroup Fluid-transfer collection assembly and method of using the same
US7033499B2 (en) 2003-02-13 2006-04-25 Ilc Dover Lp Flexible disposable vessel
JP2005127864A (ja) * 2003-10-23 2005-05-19 Japan Science & Technology Agency マイクロミキシングデバイス
JP4375101B2 (ja) * 2004-04-28 2009-12-02 横河電機株式会社 化学反応用カートリッジおよびその作製方法および化学反応用カートリッジ駆動機構
US7832429B2 (en) * 2004-10-13 2010-11-16 Rheonix, Inc. Microfluidic pump and valve structures and fabrication methods
JP2006153785A (ja) 2004-12-01 2006-06-15 Hitachi Ltd 溶液攪拌装置及び分析システム
BRPI0612577A2 (pt) 2005-06-23 2016-11-29 Koninkl Philips Electronics Nv dispositivo, aparelho, sistema e método para misturar um meio líquido
US7938573B2 (en) 2005-09-02 2011-05-10 Genefluidics, Inc. Cartridge having variable volume reservoirs
CN101312786A (zh) * 2005-11-25 2008-11-26 皇家飞利浦电子股份有限公司 具有多孔膜和无分支通道的微流体装置
CN101795770A (zh) * 2007-08-27 2010-08-04 3M创新有限公司 用于处理流体样品的器件与方法

Also Published As

Publication number Publication date
BRPI1007625B1 (pt) 2020-03-10
CN105921066B (zh) 2018-11-06
RU2011147480A (ru) 2013-05-27
KR20120016251A (ko) 2012-02-23
CN102413913A (zh) 2012-04-11
EP2421636A1 (en) 2012-02-29
KR101677751B1 (ko) 2016-11-29
US20120100630A1 (en) 2012-04-26
RU2554573C2 (ru) 2015-06-27
WO2010122464A1 (en) 2010-10-28
JP5551763B2 (ja) 2014-07-16
JP2012524899A (ja) 2012-10-18
US9174182B2 (en) 2015-11-03
EP2421636B1 (en) 2012-10-03
CN105921066A (zh) 2016-09-07

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B25G Requested change of headquarter approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/04/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 12A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2666 DE 08-02-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.