BRPI1009237A2 - inibidores de ligação de proteína quinase. - Google Patents

inibidores de ligação de proteína quinase.

Info

Publication number
BRPI1009237A2
BRPI1009237A2 BRPI1009237-4A BRPI1009237A BRPI1009237A2 BR PI1009237 A2 BRPI1009237 A2 BR PI1009237A2 BR PI1009237 A BRPI1009237 A BR PI1009237A BR PI1009237 A2 BRPI1009237 A2 BR PI1009237A2
Authority
BR
Brazil
Prior art keywords
protein kinase
binding inhibitors
kinase binding
methods
relates
Prior art date
Application number
BRPI1009237-4A
Other languages
English (en)
Inventor
Golubovskaya Vita
A. Ostrov David
G. Cance William
Original Assignee
University Of Florida Research Foundation, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Florida Research Foundation, Inc. filed Critical University Of Florida Research Foundation, Inc.
Publication of BRPI1009237A2 publication Critical patent/BRPI1009237A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"inibidores de ligação de proteína quinase" a invenção relaciona-se a compostos inibidores de ligação de proteína e métodos de identificação e uso dos mesmos. a invenção também se relaciona a composições farmacêuticas e métodos para tratar uma variedade de doenças e distúrbios, incluindo distúrbios de proliferação celular, especialmente câncer.
BRPI1009237-4A 2009-03-06 2010-03-04 inibidores de ligação de proteína quinase. BRPI1009237A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20943109P 2009-03-06 2009-03-06
US61/209.431 2009-03-06
PCT/US2010/026184 WO2010102095A2 (en) 2009-03-06 2010-03-04 Kinase protein binding inhibitors

Publications (1)

Publication Number Publication Date
BRPI1009237A2 true BRPI1009237A2 (pt) 2019-04-16

Family

ID=42710220

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009237-4A BRPI1009237A2 (pt) 2009-03-06 2010-03-04 inibidores de ligação de proteína quinase.

Country Status (10)

Country Link
US (1) US20120100227A1 (pt)
EP (1) EP2403494A4 (pt)
JP (1) JP2012519697A (pt)
KR (1) KR20110128911A (pt)
CN (1) CN102438616A (pt)
AU (1) AU2010221294A1 (pt)
BR (1) BRPI1009237A2 (pt)
CA (1) CA2754834A1 (pt)
EA (1) EA201190200A1 (pt)
WO (1) WO2010102095A2 (pt)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492332B1 (en) * 1995-12-12 2002-12-10 Omeros Corporation Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
US5851786A (en) * 1995-09-27 1998-12-22 National Jewish Center For Immunology And Respiratory Medicine Product and process to regulate actin polymerization
CA2681038A1 (en) * 2007-03-16 2008-09-25 University Of Florida Research Foundation Kinase protein binding inhibitors

Also Published As

Publication number Publication date
EP2403494A2 (en) 2012-01-11
EP2403494A4 (en) 2012-12-26
EA201190200A1 (ru) 2012-04-30
JP2012519697A (ja) 2012-08-30
CN102438616A (zh) 2012-05-02
CA2754834A1 (en) 2010-09-10
AU2010221294A1 (en) 2011-10-06
US20120100227A1 (en) 2012-04-26
WO2010102095A3 (en) 2011-01-13
WO2010102095A2 (en) 2010-09-10
KR20110128911A (ko) 2011-11-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2520 DE 25-04-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]