EA201190200A1 - Ингибиторы белкового связывания киназы - Google Patents
Ингибиторы белкового связывания киназыInfo
- Publication number
- EA201190200A1 EA201190200A1 EA201190200A EA201190200A EA201190200A1 EA 201190200 A1 EA201190200 A1 EA 201190200A1 EA 201190200 A EA201190200 A EA 201190200A EA 201190200 A EA201190200 A EA 201190200A EA 201190200 A1 EA201190200 A1 EA 201190200A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- kinase
- inhibitors
- protein linkage
- methods
- relates
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Соединение относится к ингибиторным соединениям белкового связывания и способам идентифицирования и применения их. Изобретение также относится к фармацевтическим композициям и способам лечения ряда заболеваний и нарушений, включая клеточные пролиферативные нарушения, особенно рак.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20943109P | 2009-03-06 | 2009-03-06 | |
| PCT/US2010/026184 WO2010102095A2 (en) | 2009-03-06 | 2010-03-04 | Kinase protein binding inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201190200A1 true EA201190200A1 (ru) | 2012-04-30 |
Family
ID=42710220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201190200A EA201190200A1 (ru) | 2009-03-06 | 2010-03-04 | Ингибиторы белкового связывания киназы |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20120100227A1 (ru) |
| EP (1) | EP2403494A4 (ru) |
| JP (1) | JP2012519697A (ru) |
| KR (1) | KR20110128911A (ru) |
| CN (1) | CN102438616A (ru) |
| AU (1) | AU2010221294A1 (ru) |
| BR (1) | BRPI1009237A2 (ru) |
| CA (1) | CA2754834A1 (ru) |
| EA (1) | EA201190200A1 (ru) |
| WO (1) | WO2010102095A2 (ru) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6492332B1 (en) * | 1995-12-12 | 2002-12-10 | Omeros Corporation | Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation |
| US5851786A (en) * | 1995-09-27 | 1998-12-22 | National Jewish Center For Immunology And Respiratory Medicine | Product and process to regulate actin polymerization |
| CA2681038A1 (en) * | 2007-03-16 | 2008-09-25 | University Of Florida Research Foundation | Kinase protein binding inhibitors |
-
2010
- 2010-03-04 WO PCT/US2010/026184 patent/WO2010102095A2/en not_active Ceased
- 2010-03-04 EA EA201190200A patent/EA201190200A1/ru unknown
- 2010-03-04 CA CA2754834A patent/CA2754834A1/en not_active Abandoned
- 2010-03-04 CN CN2010800185281A patent/CN102438616A/zh active Pending
- 2010-03-04 EP EP10749320A patent/EP2403494A4/en not_active Withdrawn
- 2010-03-04 AU AU2010221294A patent/AU2010221294A1/en not_active Abandoned
- 2010-03-04 BR BRPI1009237-4A patent/BRPI1009237A2/pt not_active IP Right Cessation
- 2010-03-04 JP JP2011553103A patent/JP2012519697A/ja active Pending
- 2010-03-04 KR KR1020117023311A patent/KR20110128911A/ko not_active Withdrawn
- 2010-03-04 US US13/255,053 patent/US20120100227A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2403494A2 (en) | 2012-01-11 |
| EP2403494A4 (en) | 2012-12-26 |
| BRPI1009237A2 (pt) | 2019-04-16 |
| JP2012519697A (ja) | 2012-08-30 |
| CN102438616A (zh) | 2012-05-02 |
| CA2754834A1 (en) | 2010-09-10 |
| AU2010221294A1 (en) | 2011-10-06 |
| US20120100227A1 (en) | 2012-04-26 |
| WO2010102095A3 (en) | 2011-01-13 |
| WO2010102095A2 (en) | 2010-09-10 |
| KR20110128911A (ko) | 2011-11-30 |
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