BRPI1009418A2 - nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina - Google Patents

nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina

Info

Publication number
BRPI1009418A2
BRPI1009418A2 BRPI1009418A BRPI1009418A BRPI1009418A2 BR PI1009418 A2 BRPI1009418 A2 BR PI1009418A2 BR PI1009418 A BRPI1009418 A BR PI1009418A BR PI1009418 A BRPI1009418 A BR PI1009418A BR PI1009418 A2 BRPI1009418 A2 BR PI1009418A2
Authority
BR
Brazil
Prior art keywords
nanocapsule
protein
delivering
producing
protein nanocapsule
Prior art date
Application number
BRPI1009418A
Other languages
English (en)
Inventor
Juanjuan Du
Ming Yan
Yunfeng Lu
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BRPI1009418A2 publication Critical patent/BRPI1009418A2/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B1/00Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1009418A 2009-03-09 2010-03-09 nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina BRPI1009418A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15858809P 2009-03-09 2009-03-09
US25412109P 2009-10-22 2009-10-22
PCT/US2010/026678 WO2010104865A2 (en) 2009-03-09 2010-03-09 Single protein nanocapsules for protein delivery with long-term effect

Publications (1)

Publication Number Publication Date
BRPI1009418A2 true BRPI1009418A2 (pt) 2016-03-01

Family

ID=42729056

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009418A BRPI1009418A2 (pt) 2009-03-09 2010-03-09 nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina

Country Status (11)

Country Link
US (1) US9289504B2 (pt)
EP (1) EP2406173A4 (pt)
JP (1) JP2012519733A (pt)
KR (1) KR20110126166A (pt)
CN (1) CN102438936A (pt)
AU (1) AU2010224253A1 (pt)
BR (1) BRPI1009418A2 (pt)
CA (1) CA2754885A1 (pt)
IL (1) IL215063A0 (pt)
SG (1) SG174287A1 (pt)
WO (1) WO2010104865A2 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012169973A1 (en) * 2011-06-09 2012-12-13 Agency For Science, Technology And Research A core-shell nanoparticle
AU2012278833A1 (en) 2011-07-06 2014-02-20 The Regents Of The University Of California Oral delivery of enzymes by nanocapsules for targeted metabolism of alcohol or toxic metabolites
US9993440B2 (en) 2011-09-02 2018-06-12 The Regents Of The University Of California Enzyme responsive nanocapsules for protein delivery
DK3027750T3 (da) * 2013-07-30 2019-07-15 Inofea Ag Biokatalytisk sammensætning
ES2904276T3 (es) 2013-09-27 2022-04-04 Massachusetts Inst Technology Nanoestructuras de proteínas biológicamente activas sin vehículo
US9534213B2 (en) 2014-03-04 2017-01-03 The Regents Of The University Of Michigan Spontaneously formed terminal supraparticles having nanoparticles for protein stabilization
JP6592846B2 (ja) * 2014-05-11 2019-10-23 国立大学法人 熊本大学 細胞の再プログラミング誘導方法、および多能性細胞の製造方法
WO2017027843A1 (en) 2015-08-12 2017-02-16 Massachusetts Institute Of Technology Cell surface coupling of nanoparticles
EP3377043A4 (en) 2015-11-20 2019-06-26 The Regents of The University of California DEVICABLE NANOSCAL CARRIER (DNVS) FOR ADMINISTRATION THROUGH THE BLOOD-BRAIN-BARRIER, MICE AND SKIN
EP3389641A4 (en) 2015-12-18 2019-07-31 The Regents of The University of California PROTEIN NANOCAPSULES WITH REMOVABLE ZWITTERIONIC COATING FOR PROTEIN DELIVERY
CN109843318A (zh) * 2016-05-24 2019-06-04 加利福尼亚大学董事会 用于骨再生的具有可调释放能力的生长因子纳米胶囊
EP3468581A1 (en) 2016-06-13 2019-04-17 Torque Therapeutics, Inc. Methods and compositions for promoting immune cell function
US12514929B2 (en) 2017-04-03 2026-01-06 The Regents Of The University Of California Deformable nano-scale vehicles (DNVS) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery
EP3678701A4 (en) 2017-09-05 2021-12-01 Torque Therapeutics, Inc. THERAPEUTIC PROTEIN COMPOSITIONS AND METHODS FOR PREPARING AND USING THE SAME
CN108424904A (zh) * 2017-12-12 2018-08-21 南京迪格诺斯生物技术有限公司 一种提高文库构建试剂稳定性的方法
CN113544270A (zh) * 2018-12-23 2021-10-22 美国杰特贝林生物制品有限公司 用于递送细胞调节剂的纳米胶囊
US20220175957A1 (en) * 2019-02-19 2022-06-09 The Regents Of The University Of California Delivery of macromolecules into the central nervous system via the bloodstream
KR20230134516A (ko) * 2021-01-22 2023-09-21 고쿠리츠다이가쿠호진 도호쿠다이가쿠 복합체, 맥관 조영제, x선 조영제, 복합체의 제조 방법,및 맥관의 구조 변화를 포착하는 촬영 방법
CN112813104B (zh) * 2021-03-20 2022-09-23 中国人民解放军军事科学院军事医学研究院 一种蛋白-聚合物复合纳米材料基因载体的制备方法和应用
CN113398253B (zh) * 2021-05-14 2023-01-24 北京化工大学 β2微球蛋白聚集抑制剂
CN119837841B (zh) * 2024-03-13 2025-10-31 上海交通大学 一种用于皮肤抗炎的蓝萼甲素纳米透皮递送系统及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2782440B2 (ja) 1988-10-06 1998-07-30 忠一 平山 重合触媒及びその製造方法
US6716450B1 (en) * 2000-05-18 2004-04-06 The United States Of America As Represented By The Secretary Of The Army Enhancing protein activity through nanoencapsulation
WO2003082316A1 (en) 2002-03-29 2003-10-09 The Regents Of The University Of California Microgel particles for the delivery of bioactive materials
WO2004096998A2 (en) * 2003-04-29 2004-11-11 Vanderbilt University Nanoparticular tumor targeting and therapy
US7217410B2 (en) 2003-06-17 2007-05-15 The Board Of Trustees Of The Universtiy Of Illinois Surface modified protein microparticles
WO2006010083A2 (en) * 2004-07-08 2006-01-26 Molecular Therapeutics, Inc. Biodegradable nanoparticles
WO2008109483A1 (en) 2007-03-02 2008-09-12 The Board Of Trustees Of The University Of Illinois Particulate drug delivery

Also Published As

Publication number Publication date
WO2010104865A3 (en) 2011-01-13
US20110318297A1 (en) 2011-12-29
EP2406173A4 (en) 2016-04-06
CA2754885A1 (en) 2010-09-16
AU2010224253A2 (en) 2012-02-16
KR20110126166A (ko) 2011-11-22
JP2012519733A (ja) 2012-08-30
CN102438936A (zh) 2012-05-02
US9289504B2 (en) 2016-03-22
SG174287A1 (en) 2011-10-28
EP2406173A2 (en) 2012-01-18
AU2010224253A1 (en) 2011-10-27
WO2010104865A2 (en) 2010-09-16
IL215063A0 (en) 2011-11-30

Similar Documents

Publication Publication Date Title
BRPI1009418A2 (pt) nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina
BRPI0906668A2 (pt) bocal e inalador e método de produção de bocal
BR112012001302A2 (pt) extrudado de proteina, produto alimenticio e metodo de produzir um extruturado de proteina com uma estrutura amorfa
BRPI1008971A2 (pt) métodos para preparar uma proteína biológica condicionalmente ativa, e um modificador de resposta biológica condicionalmente ativo, proteína biológica condicionalmente ativa, e, composição farmacêutica
DK2501822T3 (da) Fremgangsmåder til forbedret proteinproduktion
BRPI0925037A2 (pt) Composição contendo piceatanol e método de produzir a composição contendo piceatanol.
HUE058971T2 (hu) RSV F fehérjekészítmények és eljárások azok elõállítására
HUE057713T2 (hu) A protein A (SPA) variánsaival kapcsolatos készítmények és módszerek
BRPI0914916A2 (pt) anticorpos de interleucina-20 anti-humanos, assim como método de produção dos mesmos
HRP20181320T8 (hr) Ljudska anti-tau protutijela
BR112012002118A2 (pt) bocal e metodos de produção do mesmo
BRPI0822775A2 (pt) Método de obtenção de uma proteína heteróloga, purificada, biologicamente ativa.
BR112013033811A2 (pt) composição, método de preparação da composição, e, composto
PT2371019T (pt) Acumulador de lítio e método de produção do mesmo
BRPI0815036A2 (pt) Método de produção de proteína heterogêneas
FI20115211A0 (fi) Pisteen, missä väri muuttuu harmaaksi määritysmenetelmä titaanivalkoisen valmistusprosessissa
HRP20170959T1 (hr) Farmaceutska suspenzija
BR112012000195A2 (pt) método de produção de componentes compósitos avançados.
KR101081596B9 (ko) 음악분수 시스템 및 연출 방법
BRPI0820644A2 (pt) método de preparação de uma composição, e, composição
BRPI0917684A2 (pt) método terapêutico homeopático
EP2447364A4 (en) MODIFIED PROTEIN CONJUGATED TO BIOTIN
BRPI0718565A2 (pt) Forma de dosagem sólida, e, método de produção de uma forma de dosagem sólida.
EP2393836A4 (en) SAM-6 VARIANTS, TARGET AND METHODS OF USING SAME
SG10201602874VA (en) Protein production method

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]