BRPI1009418A2 - nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina - Google Patents

nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina

Info

Publication number
BRPI1009418A2
BRPI1009418A2 BRPI1009418A BRPI1009418A BRPI1009418A2 BR PI1009418 A2 BRPI1009418 A2 BR PI1009418A2 BR PI1009418 A BRPI1009418 A BR PI1009418A BR PI1009418 A BRPI1009418 A BR PI1009418A BR PI1009418 A2 BRPI1009418 A2 BR PI1009418A2
Authority
BR
Brazil
Prior art keywords
nanocapsule
protein
delivering
producing
protein nanocapsule
Prior art date
Application number
BRPI1009418A
Other languages
English (en)
Inventor
Juanjuan Du
Ming Yan
Yunfeng Lu
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BRPI1009418A2 publication Critical patent/BRPI1009418A2/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B1/00Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1009418A 2009-03-09 2010-03-09 nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina BRPI1009418A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15858809P 2009-03-09 2009-03-09
US25412109P 2009-10-22 2009-10-22
PCT/US2010/026678 WO2010104865A2 (en) 2009-03-09 2010-03-09 Single protein nanocapsules for protein delivery with long-term effect

Publications (1)

Publication Number Publication Date
BRPI1009418A2 true BRPI1009418A2 (pt) 2016-03-01

Family

ID=42729056

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009418A BRPI1009418A2 (pt) 2009-03-09 2010-03-09 nanocapsula de proteina, metodo de pdroduzir uma nanocapsula, e metodo de distribuir uma proteina

Country Status (11)

Country Link
US (1) US9289504B2 (pt)
EP (1) EP2406173A4 (pt)
JP (1) JP2012519733A (pt)
KR (1) KR20110126166A (pt)
CN (1) CN102438936A (pt)
AU (1) AU2010224253A1 (pt)
BR (1) BRPI1009418A2 (pt)
CA (1) CA2754885A1 (pt)
IL (1) IL215063A0 (pt)
SG (1) SG174287A1 (pt)
WO (1) WO2010104865A2 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012169973A1 (en) * 2011-06-09 2012-12-13 Agency For Science, Technology And Research A core-shell nanoparticle
JP2014522649A (ja) * 2011-07-06 2014-09-08 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 多酵素ナノ複合体
US9993440B2 (en) 2011-09-02 2018-06-12 The Regents Of The University Of California Enzyme responsive nanocapsules for protein delivery
PL3027750T3 (pl) * 2013-07-30 2019-09-30 Inofea Ag Kompozycja biokatalityczna
CA3191031A1 (en) 2013-09-27 2015-04-02 Massachusetts Institute Of Technology Carrier-free biologically-active protein nanostructures
US9534213B2 (en) 2014-03-04 2017-01-03 The Regents Of The University Of Michigan Spontaneously formed terminal supraparticles having nanoparticles for protein stabilization
EP3144384B1 (en) * 2014-05-11 2020-08-19 National University Corporation Kumamoto University Method for inducing cell reprogramming, and method for producing pluripotent cells
WO2017027843A1 (en) 2015-08-12 2017-02-16 Massachusetts Institute Of Technology Cell surface coupling of nanoparticles
WO2017087685A1 (en) 2015-11-20 2017-05-26 The Regents Of The University Of California Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery
US11103462B2 (en) 2015-12-18 2021-08-31 The Regents Of The University Of California Protein nanocapsules with detachable zwitterionic coating for protein delivery
EP3463428A4 (en) * 2016-05-24 2020-01-08 The Regents of the University of California GROWTH FACTOR NANO CAPSULES WITH TUNABLE RELEASE FOR BONE REGENERATION
CN109715196A (zh) 2016-06-13 2019-05-03 转矩医疗股份有限公司 用于促进免疫细胞功能的组合物和方法
CA3058782A1 (en) 2017-04-03 2018-10-11 The Regents Of The University Of California Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery
CA3074826A1 (en) 2017-09-05 2019-03-14 Torque Therapeutics, Inc. Therapeutic protein compositions and methods of making and using the same
CN108424904A (zh) * 2017-12-12 2018-08-21 南京迪格诺斯生物技术有限公司 一种提高文库构建试剂稳定性的方法
CN113544270A (zh) * 2018-12-23 2021-10-22 美国杰特贝林生物制品有限公司 用于递送细胞调节剂的纳米胶囊
EP3927366B1 (en) * 2019-02-19 2024-09-25 The Regents Of The University Of California Delivery of macromolecules into the central nervous system via the bloodstream
US20240139347A1 (en) * 2021-01-22 2024-05-02 Tohoku University Complex, vascular contrast agent, x-ray contrast agent, method for producing complex, and imaging method for capturing structural change in vessel
CN112813104B (zh) * 2021-03-20 2022-09-23 中国人民解放军军事科学院军事医学研究院 一种蛋白-聚合物复合纳米材料基因载体的制备方法和应用
CN113398253B (zh) * 2021-05-14 2023-01-24 北京化工大学 β2微球蛋白聚集抑制剂
CN119837841B (zh) * 2024-03-13 2025-10-31 上海交通大学 一种用于皮肤抗炎的蓝萼甲素纳米透皮递送系统及其制备方法
CN119837822A (zh) * 2024-06-18 2025-04-18 上海交通大学 一种基于蛋白载体的活性成分毛囊透皮递送系统

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2782440B2 (ja) * 1988-10-06 1998-07-30 忠一 平山 重合触媒及びその製造方法
US6716450B1 (en) 2000-05-18 2004-04-06 The United States Of America As Represented By The Secretary Of The Army Enhancing protein activity through nanoencapsulation
CA2479920A1 (en) 2002-03-29 2003-10-09 The Regents Of The University Of California Microgel particles for the delivery of bioactive materials
WO2004096998A2 (en) * 2003-04-29 2004-11-11 Vanderbilt University Nanoparticular tumor targeting and therapy
US7217410B2 (en) * 2003-06-17 2007-05-15 The Board Of Trustees Of The Universtiy Of Illinois Surface modified protein microparticles
US20070009441A1 (en) * 2004-07-08 2007-01-11 Molecular Therapeutics, Inc. Biodegradable nanoparticles
EP2132133A4 (en) * 2007-03-02 2013-04-17 Univ Illinois RELEASE OF PARTICULATE ACTIVE SUBSTANCES

Also Published As

Publication number Publication date
AU2010224253A2 (en) 2012-02-16
EP2406173A4 (en) 2016-04-06
JP2012519733A (ja) 2012-08-30
US9289504B2 (en) 2016-03-22
CA2754885A1 (en) 2010-09-16
WO2010104865A2 (en) 2010-09-16
EP2406173A2 (en) 2012-01-18
KR20110126166A (ko) 2011-11-22
SG174287A1 (en) 2011-10-28
US20110318297A1 (en) 2011-12-29
WO2010104865A3 (en) 2011-01-13
IL215063A0 (en) 2011-11-30
AU2010224253A1 (en) 2011-10-27
CN102438936A (zh) 2012-05-02

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]