BRPI0815036A2 - Método de produção de proteína heterogêneas - Google Patents

Método de produção de proteína heterogêneas

Info

Publication number
BRPI0815036A2
BRPI0815036A2 BRPI0815036-2A2A BRPI0815036A BRPI0815036A2 BR PI0815036 A2 BRPI0815036 A2 BR PI0815036A2 BR PI0815036 A BRPI0815036 A BR PI0815036A BR PI0815036 A2 BRPI0815036 A2 BR PI0815036A2
Authority
BR
Brazil
Prior art keywords
production method
protein production
heterogeneous protein
heterogeneous
protein
Prior art date
Application number
BRPI0815036-2A2A
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Tomoya Sugiyama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0815036A2 publication Critical patent/BRPI0815036A2/pt
Publication of BRPI0815036B1 publication Critical patent/BRPI0815036B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01002—Alanine transaminase (2.6.1.2), i.e. alanine-aminotransferase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
BRPI0815036-2A 2007-08-07 2008-08-06 Métodos para produção de um polipeptídeo e para preparação de um produto farmacêutico BRPI0815036B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007-205158 2007-08-07
JP2007205158 2007-08-07
PCT/JP2008/064095 WO2009020144A1 (ja) 2007-08-07 2008-08-06 異種タンパク質の製造方法

Publications (2)

Publication Number Publication Date
BRPI0815036A2 true BRPI0815036A2 (pt) 2014-10-14
BRPI0815036B1 BRPI0815036B1 (pt) 2022-09-20

Family

ID=40341376

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815036-2A BRPI0815036B1 (pt) 2007-08-07 2008-08-06 Métodos para produção de um polipeptídeo e para preparação de um produto farmacêutico

Country Status (14)

Country Link
US (3) US8697397B2 (pt)
EP (1) EP2186905B1 (pt)
JP (1) JP5337033B2 (pt)
KR (1) KR101577839B1 (pt)
CN (1) CN101809161B (pt)
AU (1) AU2008284753B2 (pt)
BR (1) BRPI0815036B1 (pt)
CA (1) CA2695849C (pt)
DK (1) DK2186905T3 (pt)
ES (1) ES2591284T3 (pt)
MX (1) MX2010001319A (pt)
RU (1) RU2487168C2 (pt)
TW (1) TWI463013B (pt)
WO (1) WO2009020144A1 (pt)

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EP2135946B1 (en) 2007-03-15 2015-12-09 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
US8697397B2 (en) 2007-08-07 2014-04-15 Chugai Seiyaku Kabushiki Kaisha Method of producing heterogeneous protein
RU2486245C2 (ru) 2007-10-15 2013-06-27 Чугаи Сейяку Кабусики Кайся Способ получения клетки, способной продуцировать гетеропротеины с высоким выходом
CA2703493C (en) 2007-10-24 2016-11-08 Chugai Seiyaku Kabushiki Kaisha A cell for use in production of heteroproteins and production method using the same
US8741601B2 (en) 2009-04-22 2014-06-03 Chugai Seiyaku Kabushiki Kaisha Method for producing a cell capable of high-yield production of heteroproteins
PL2576580T3 (pl) 2010-05-28 2017-03-31 F.Hoffmann-La Roche Ag Zmniejszenie poziomu mleczanu i zwiększenie wytwarzania polipeptydu przez obniżenie poziomu ekspresji dehydrogenazy mleczanowej i kinazy dehydrogenazy pirogronianowej
BR112013024781B1 (pt) 2011-04-01 2021-09-08 Chugai Seiyaku Kabushiki Kaisha Métodos de produção de um anticorpo e de uma composição farmacêutica
SG11201502801RA (en) 2012-10-10 2015-06-29 Chugai Pharmaceutical Co Ltd Method for establishing modified host cell
BR112015021993A8 (pt) * 2013-03-15 2019-12-03 Genentech Inc polipeptídeo, métodos para sua produção, métodos para cultivo de uma célula, composição farmacêutica, kit, e meio de cultura celular
AU2014369177B2 (en) 2013-12-20 2017-04-20 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
EP3604331A1 (en) * 2013-12-20 2020-02-05 Novartis AG Novel eukaryotic cells and methods for recombinantly expressing a product of interest
CN103923872B (zh) * 2014-04-17 2015-11-18 湖北工业大学 一种米曲霉活力强化剂及其培养方法
JP6657500B2 (ja) * 2015-03-31 2020-03-04 エスゼット ディージェイアイ テクノロジー カンパニー リミテッドＳｚ Ｄｊｉ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏ．，Ｌｔｄ モバイルプラットフォームの制御方法およびシステム
TWI899515B (zh) 2015-08-04 2025-10-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
WO2020122049A1 (ja) 2018-12-11 2020-06-18 富士フイルム株式会社 動物細胞、動物細胞の製造方法および目的タンパク質の製造方法
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
KR102479900B1 (ko) * 2020-12-11 2022-12-26 대한민국 내염성 증진 신품종 식물
CN118755734A (zh) * 2024-06-28 2024-10-11 中国水稻研究所 一种改良水稻产量和品质的方法

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US6225115B1 (en) * 1992-03-04 2001-05-01 Synaptic Pharmaceutical Corporation DNA encoding taurine and GABA transporters and uses thereof
JPH07507446A (ja) * 1992-03-04 1995-08-24 シナプティック・ファーマスーティカル・コーポレーション タウリン及びｇａｂａの輸送体をコードするｄｎａ並びにその使用
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JP3630453B2 (ja) 1994-09-30 2005-03-16 中外製薬株式会社 Ｉｌ−６レセプター抗体を有効成分とする未熟型骨髄腫細胞治療剤
AU695117B2 (en) 1994-10-06 1998-08-06 Hoechst Aktiengesellschaft Regulated genes by stimulation of chondrocytes with IL-1beta
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AU2002308701A1 (en) * 2001-05-14 2002-11-25 University Of Maryland, Baltimore Novel alanine transaminase enzyme and methods of use
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CA2535156A1 (en) * 2003-08-08 2005-02-24 Abgenix, Inc. Antibodies directed to parathyroid hormone (pth) and uses thereof
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KR100789645B1 (ko) * 2004-04-14 2007-12-27 주식회사유한양행 Ｂ형 간염바이러스의 ｓ-표면항원을 인식하는 인간화 항체및 이의 제조방법
PL1674111T3 (pl) * 2004-07-09 2011-04-29 Chugai Pharmaceutical Co Ltd Przeciwciała anty-glipikan 3
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EP2011880B1 (en) * 2006-04-13 2012-10-24 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
EP2135946B1 (en) 2007-03-15 2015-12-09 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
US8697397B2 (en) 2007-08-07 2014-04-15 Chugai Seiyaku Kabushiki Kaisha Method of producing heterogeneous protein
RU2486245C2 (ru) 2007-10-15 2013-06-27 Чугаи Сейяку Кабусики Кайся Способ получения клетки, способной продуцировать гетеропротеины с высоким выходом
CA2703493C (en) * 2007-10-24 2016-11-08 Chugai Seiyaku Kabushiki Kaisha A cell for use in production of heteroproteins and production method using the same
US8741601B2 (en) * 2009-04-22 2014-06-03 Chugai Seiyaku Kabushiki Kaisha Method for producing a cell capable of high-yield production of heteroproteins

Also Published As

Publication number Publication date
US9499618B2 (en) 2016-11-22
CN101809161A (zh) 2010-08-18
RU2010108308A (ru) 2011-09-20
MX2010001319A (es) 2010-06-01
DK2186905T3 (en) 2016-09-19
EP2186905A4 (en) 2010-09-01
US20100167346A1 (en) 2010-07-01
TW200920845A (en) 2009-05-16
HK1143608A1 (zh) 2011-01-07
CN101809161B (zh) 2014-03-12
CA2695849A1 (en) 2009-02-12
WO2009020144A1 (ja) 2009-02-12
KR101577839B1 (ko) 2015-12-15
US8697397B2 (en) 2014-04-15
CA2695849C (en) 2018-10-16
RU2487168C2 (ru) 2013-07-10
EP2186905A1 (en) 2010-05-19
US20150315624A1 (en) 2015-11-05
JPWO2009020144A1 (ja) 2010-11-04
AU2008284753A1 (en) 2009-02-12
US9284374B2 (en) 2016-03-15
KR20100057598A (ko) 2010-05-31
EP2186905B1 (en) 2016-07-13
US20140309405A1 (en) 2014-10-16
JP5337033B2 (ja) 2013-11-06
BRPI0815036B1 (pt) 2022-09-20
AU2008284753B2 (en) 2014-01-16
ES2591284T3 (es) 2016-11-25
TWI463013B (zh) 2014-12-01

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/08/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.