BRPI0815036A2 - Método de produção de proteína heterogêneas - Google Patents

Método de produção de proteína heterogêneas

Info

Publication number
BRPI0815036A2
BRPI0815036A2 BRPI0815036-2A2A BRPI0815036A BRPI0815036A2 BR PI0815036 A2 BRPI0815036 A2 BR PI0815036A2 BR PI0815036 A BRPI0815036 A BR PI0815036A BR PI0815036 A2 BRPI0815036 A2 BR PI0815036A2
Authority
BR
Brazil
Prior art keywords
production method
protein production
heterogeneous protein
heterogeneous
protein
Prior art date
Application number
BRPI0815036-2A2A
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Tomoya Sugiyama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0815036A2 publication Critical patent/BRPI0815036A2/pt
Publication of BRPI0815036B1 publication Critical patent/BRPI0815036B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1096Transferases (2.) transferring nitrogenous groups (2.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y206/00Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01Transaminases (2.6.1)
    • C12Y206/01002Alanine transaminase (2.6.1.2), i.e. alanine-aminotransferase
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
BRPI0815036-2A 2007-08-07 2008-08-06 Métodos para produção de um polipeptídeo e para preparação de um produto farmacêutico BRPI0815036B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007205158 2007-08-07
JP2007-205158 2007-08-07
PCT/JP2008/064095 WO2009020144A1 (ja) 2007-08-07 2008-08-06 異種タンパク質の製造方法

Publications (2)

Publication Number Publication Date
BRPI0815036A2 true BRPI0815036A2 (pt) 2014-10-14
BRPI0815036B1 BRPI0815036B1 (pt) 2022-09-20

Family

ID=40341376

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815036-2A BRPI0815036B1 (pt) 2007-08-07 2008-08-06 Métodos para produção de um polipeptídeo e para preparação de um produto farmacêutico

Country Status (14)

Country Link
US (3) US8697397B2 (pt)
EP (1) EP2186905B1 (pt)
JP (1) JP5337033B2 (pt)
KR (1) KR101577839B1 (pt)
CN (1) CN101809161B (pt)
AU (1) AU2008284753B2 (pt)
BR (1) BRPI0815036B1 (pt)
CA (1) CA2695849C (pt)
DK (1) DK2186905T3 (pt)
ES (1) ES2591284T3 (pt)
MX (1) MX2010001319A (pt)
RU (1) RU2487168C2 (pt)
TW (1) TWI463013B (pt)
WO (1) WO2009020144A1 (pt)

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CN101421411B (zh) 2006-04-13 2015-06-03 中外制药株式会社 牛磺酸转运蛋白基因
WO2008114673A1 (ja) 2007-03-15 2008-09-25 Chugai Seiyaku Kabushiki Kaisha ポリペプチドの製造方法
ES2591284T3 (es) 2007-08-07 2016-11-25 Chugai Seiyaku Kabushiki Kaisha Método para la producción de proteínas heterogéneas
WO2009051109A1 (ja) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
AU2008314973C1 (en) * 2007-10-24 2014-05-08 Chugai Seiyaku Kabushiki Kaisha A cell for use in production of heteroproteins and production method using the same
US8741601B2 (en) 2009-04-22 2014-06-03 Chugai Seiyaku Kabushiki Kaisha Method for producing a cell capable of high-yield production of heteroproteins
WO2011150241A2 (en) 2010-05-28 2011-12-01 Genentech, Inc. Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase
CA2830013C (en) * 2011-04-01 2020-01-07 Chugai Seiyaku Kabushiki Kaisha Recombinant polypeptide production method
EP2921554B1 (en) * 2012-10-10 2019-12-04 Chugai Seiyaku Kabushiki Kaisha Method for establishing modified host cell
WO2014145098A1 (en) 2013-03-15 2014-09-18 Genentech, Inc. Cell culture compositions with antioxidants and methods for polypeptide production
CA2934411C (en) 2013-12-20 2022-05-03 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
SG11201604218RA (en) 2013-12-20 2016-07-28 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
CN103923872B (zh) * 2014-04-17 2015-11-18 湖北工业大学 一种米曲霉活力强化剂及其培养方法
CN111273690A (zh) * 2015-03-31 2020-06-12 深圳市大疆创新科技有限公司 移动平台操作系统及方法
TWI870789B (zh) 2015-08-04 2025-01-21 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
JP7123168B2 (ja) 2018-12-11 2022-08-22 富士フイルム株式会社 動物細胞、動物細胞の製造方法および目的タンパク質の製造方法
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
KR102479900B1 (ko) * 2020-12-11 2022-12-26 대한민국 내염성 증진 신품종 식물
CN118755734A (zh) * 2024-06-28 2024-10-11 中国水稻研究所 一种改良水稻产量和品质的方法

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CA2131444A1 (en) * 1992-03-04 1993-09-16 Kelli E. Smith Dna encoding taurine and gaba transporters and uses thereof
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
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AU695117B2 (en) 1994-10-06 1998-08-06 Hoechst Aktiengesellschaft Regulated genes by stimulation of chondrocytes with IL-1beta
JPH09203734A (ja) 1996-01-26 1997-08-05 Sumitomo Electric Ind Ltd 抗血清、抗体、リガンド及びそれらの検出方法
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JPH10191984A (ja) * 1997-01-09 1998-07-28 Oriental Yeast Co Ltd 活性型ヒトaltの製造法
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US7288253B2 (en) * 2003-08-08 2007-10-30 Amgen Fremont, Inc. Antibodies directed to parathyroid hormone (PTH) and uses thereof
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KR100789645B1 (ko) * 2004-04-14 2007-12-27 주식회사유한양행 B형 간염바이러스의 s-표면항원을 인식하는 인간화 항체및 이의 제조방법
CA2544692C (en) 2004-07-09 2014-04-01 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
CN1838969A (zh) 2004-10-07 2006-09-27 三仪股份有限公司 经皮和经粘膜制剂
PA8672101A1 (es) 2005-04-29 2006-12-07 Centocor Inc Anticuerpos anti-il-6, composiciones, métodos y usos
WO2007056507A1 (en) * 2005-11-09 2007-05-18 Abbott Laboratories Human bnp immunospecific antibodies
AR059119A1 (es) * 2005-12-23 2008-03-12 Arcadia Biosciences Inc Utilizacion eficaz de nitrogeno en plantas monocotiledoneas
CH697825B1 (de) 2006-02-01 2009-02-27 Isofer Ag Auffangzaun für Lawinen Stein- oder Holzschlag.
CN101421411B (zh) 2006-04-13 2015-06-03 中外制药株式会社 牛磺酸转运蛋白基因
WO2008114673A1 (ja) 2007-03-15 2008-09-25 Chugai Seiyaku Kabushiki Kaisha ポリペプチドの製造方法
ES2591284T3 (es) * 2007-08-07 2016-11-25 Chugai Seiyaku Kabushiki Kaisha Método para la producción de proteínas heterogéneas
WO2009051109A1 (ja) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
AU2008314973C1 (en) 2007-10-24 2014-05-08 Chugai Seiyaku Kabushiki Kaisha A cell for use in production of heteroproteins and production method using the same
US8741601B2 (en) * 2009-04-22 2014-06-03 Chugai Seiyaku Kabushiki Kaisha Method for producing a cell capable of high-yield production of heteroproteins

Also Published As

Publication number Publication date
ES2591284T3 (es) 2016-11-25
US9499618B2 (en) 2016-11-22
TW200920845A (en) 2009-05-16
EP2186905A1 (en) 2010-05-19
CN101809161B (zh) 2014-03-12
EP2186905A4 (en) 2010-09-01
MX2010001319A (es) 2010-06-01
DK2186905T3 (en) 2016-09-19
RU2487168C2 (ru) 2013-07-10
US9284374B2 (en) 2016-03-15
AU2008284753A1 (en) 2009-02-12
CN101809161A (zh) 2010-08-18
CA2695849C (en) 2018-10-16
US8697397B2 (en) 2014-04-15
KR20100057598A (ko) 2010-05-31
CA2695849A1 (en) 2009-02-12
RU2010108308A (ru) 2011-09-20
US20150315624A1 (en) 2015-11-05
AU2008284753B2 (en) 2014-01-16
JPWO2009020144A1 (ja) 2010-11-04
EP2186905B1 (en) 2016-07-13
WO2009020144A1 (ja) 2009-02-12
TWI463013B (zh) 2014-12-01
US20100167346A1 (en) 2010-07-01
US20140309405A1 (en) 2014-10-16
KR101577839B1 (ko) 2015-12-15
HK1143608A1 (zh) 2011-01-07
BRPI0815036B1 (pt) 2022-09-20
JP5337033B2 (ja) 2013-11-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/08/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.