BRPI1009854A2 - Processo para preparar composto antiviral - Google Patents

Processo para preparar composto antiviral

Info

Publication number
BRPI1009854A2
BRPI1009854A2 BRPI1009854-2A BRPI1009854A BRPI1009854A2 BR PI1009854 A2 BRPI1009854 A2 BR PI1009854A2 BR PI1009854 A BRPI1009854 A BR PI1009854A BR PI1009854 A2 BRPI1009854 A2 BR PI1009854A2
Authority
BR
Brazil
Prior art keywords
antiviral compound
preparing antiviral
preparing
compound
antiviral
Prior art date
Application number
BRPI1009854-2A
Other languages
English (en)
Inventor
James J Napier
Jean-Christophe Califano
Su Yu
Calvin L Becker
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI1009854A2 publication Critical patent/BRPI1009854A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI1009854-2A 2009-03-24 2010-03-24 Processo para preparar composto antiviral BRPI1009854A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16270509P 2009-03-24 2009-03-24
US31671310P 2010-03-23 2010-03-23
PCT/US2010/028433 WO2010111348A1 (en) 2009-03-24 2010-03-24 Process for preparing antiviral compound

Publications (1)

Publication Number Publication Date
BRPI1009854A2 true BRPI1009854A2 (pt) 2015-08-25

Family

ID=42136100

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009854-2A BRPI1009854A2 (pt) 2009-03-24 2010-03-24 Processo para preparar composto antiviral

Country Status (23)

Country Link
EP (1) EP2411372B1 (pt)
JP (1) JP5744003B2 (pt)
KR (1) KR101665955B1 (pt)
CN (1) CN102361858B (pt)
AU (1) AU2010229975B2 (pt)
BR (1) BRPI1009854A2 (pt)
CA (1) CA2753825C (pt)
CL (1) CL2011002278A1 (pt)
CO (1) CO6450678A2 (pt)
CR (1) CR20110524A (pt)
DO (1) DOP2011000297A (pt)
EC (1) ECSP11011415A (pt)
ES (1) ES2488821T3 (pt)
GT (1) GT201100241A (pt)
IL (1) IL214858A (pt)
MX (1) MX2011010049A (pt)
MY (1) MY169288A (pt)
NZ (1) NZ594923A (pt)
PE (1) PE20120519A1 (pt)
RU (1) RU2524573C2 (pt)
SG (1) SG174211A1 (pt)
WO (1) WO2010111348A1 (pt)
ZA (1) ZA201106511B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8975443B2 (en) 2010-07-16 2015-03-10 Abbvie Inc. Phosphine ligands for catalytic reactions
US8841487B2 (en) 2010-07-16 2014-09-23 Abbvie Inc. Phosphine ligands for catalytic reactions
US9255074B2 (en) 2010-07-16 2016-02-09 Abbvie Inc. Process for preparing antiviral compounds
NZ705225A (en) 2010-07-16 2016-11-25 Abbvie Bahamas Ltd Process for preparing antiviral compounds
TWI558400B (zh) * 2011-03-18 2016-11-21 艾伯維有限公司 苯基尿嘧啶化合物之調配物
US20160375017A1 (en) 2015-06-26 2016-12-29 Abbvie Inc. Solid Pharmaceutical Compositions for Treating HCV

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60020584T2 (de) * 1999-09-20 2006-04-27 Fuji Photo Film Co., Ltd., Minami-Ashigara Verbindungen zur fluoreszenz-kennzeichnung
WO2001021642A1 (de) * 1999-09-22 2001-03-29 Aventis Pharma Deutschland Gmbh 4-benzylaminochinoline konjugaten mit gallensaeure und ihre heteroanalogen, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und deren anwendung
DE10051981A1 (de) * 2000-10-20 2002-05-02 Bayer Ag Substituierte Phenyluracile
BRPI0712806A2 (pt) * 2006-05-30 2012-10-23 Arrow Therapeutics Ltd uso de um composto, derivado de bifenila ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, produto, e, método para melhorar uma infecção por hepatite c em um paciente
AR070027A1 (es) * 2007-09-17 2010-03-10 Abbott Lab Agentes anti-infecciosos contra el virus hcv
HRP20110632T1 (hr) * 2007-09-17 2011-10-31 Abbott Laboratories N-fenil-diokso-hidropirimidini korisni kao inhibitori virusa hepatitisa c (hcv)
MX2011000656A (es) * 2008-07-23 2011-02-23 Hoffmann La Roche Compuestos heterociclicos antiviricos.

Also Published As

Publication number Publication date
HK1166798A1 (en) 2012-11-09
PE20120519A1 (es) 2012-06-03
DOP2011000297A (es) 2011-10-15
IL214858A (en) 2015-05-31
JP5744003B2 (ja) 2015-07-01
AU2010229975A1 (en) 2011-09-29
RU2524573C2 (ru) 2014-07-27
KR20110137372A (ko) 2011-12-22
CN102361858B (zh) 2014-07-23
ZA201106511B (en) 2012-05-30
ECSP11011415A (es) 2011-11-30
AU2010229975B2 (en) 2015-05-21
CO6450678A2 (es) 2012-05-31
WO2010111348A1 (en) 2010-09-30
MY169288A (en) 2019-03-21
IL214858A0 (en) 2011-11-30
CA2753825C (en) 2017-10-17
CL2011002278A1 (es) 2012-03-09
NZ594923A (en) 2013-11-29
RU2011142757A (ru) 2013-04-27
CA2753825A1 (en) 2010-09-30
ES2488821T3 (es) 2014-08-29
EP2411372B1 (en) 2014-07-23
CN102361858A (zh) 2012-02-22
EP2411372A1 (en) 2012-02-01
CR20110524A (es) 2012-01-19
KR101665955B1 (ko) 2016-10-13
SG174211A1 (en) 2011-10-28
JP2012521990A (ja) 2012-09-20
MX2011010049A (es) 2011-10-11
GT201100241A (es) 2015-08-19

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: ABBVIE INC. (US)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C07D 239/54 , C07D 311/08

Ipc: C07D 239/54 (2006.01), C07D 311/08 (2006.01), A61P

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements