BRPI1010068A2 - "sistema agitador, dispositivo, método para cultivo de células animais, método para produzir um polipeptídeo, uso de um sistema agitador e dispositivos para cultivar células animais" - Google Patents

"sistema agitador, dispositivo, método para cultivo de células animais, método para produzir um polipeptídeo, uso de um sistema agitador e dispositivos para cultivar células animais"

Info

Publication number
BRPI1010068A2
BRPI1010068A2 BRPI1010068A BRPI1010068A BRPI1010068A2 BR PI1010068 A2 BRPI1010068 A2 BR PI1010068A2 BR PI1010068 A BRPI1010068 A BR PI1010068A BR PI1010068 A BRPI1010068 A BR PI1010068A BR PI1010068 A2 BRPI1010068 A2 BR PI1010068A2
Authority
BR
Brazil
Prior art keywords
animal cells
culturing animal
shaker system
polypeptide
producing
Prior art date
Application number
BRPI1010068A
Other languages
English (en)
Inventor
Alexander Alisch
Claus Wallerius
Joerg Thiele
Marco Jenzsch
Michael Pohlscheidt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41478681&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1010068(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI1010068A2 publication Critical patent/BRPI1010068A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/111—Centrifugal stirrers, i.e. stirrers with radial outlets; Stirrers of the turbine type, e.g. with means to guide the flow
    • B01F27/1111—Centrifugal stirrers, i.e. stirrers with radial outlets; Stirrers of the turbine type, e.g. with means to guide the flow with a flat disc or with a disc-like element equipped with blades, e.g. Rushton turbine
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/19—Stirrers with two or more mixing elements mounted in sequence on the same axis
    • B01F27/192—Stirrers with two or more mixing elements mounted in sequence on the same axis with dissimilar elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/81—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis the stirrers having central axial inflow and substantially radial outflow
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/02—Apparatus for enzymology or microbiology with agitation means; with heat exchange means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/04—Apparatus for enzymology or microbiology with gas introduction means
    • C12M1/06—Apparatus for enzymology or microbiology with gas introduction means with agitator, e.g. impeller
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C12M27/08—Stirrer or mobile mixing elements with different stirrer shapes in one shaft or axis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/111—Centrifugal stirrers, i.e. stirrers with radial outlets; Stirrers of the turbine type, e.g. with means to guide the flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/113—Propeller-shaped stirrers for producing an axial flow, e.g. shaped like a ship or aircraft propeller
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/115—Stirrers characterised by the configuration of the stirrers comprising discs or disc-like elements essentially perpendicular to the stirrer shaft axis
    • B01F27/1152—Stirrers characterised by the configuration of the stirrers comprising discs or disc-like elements essentially perpendicular to the stirrer shaft axis with separate elements other than discs fixed on the discs, e.g. vanes fixed on the discs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI1010068A 2009-07-24 2010-07-23 "sistema agitador, dispositivo, método para cultivo de células animais, método para produzir um polipeptídeo, uso de um sistema agitador e dispositivos para cultivar células animais" BRPI1010068A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09009639 2009-07-24
PCT/EP2010/004520 WO2011009625A1 (en) 2009-07-24 2010-07-23 Stirrer system

Publications (1)

Publication Number Publication Date
BRPI1010068A2 true BRPI1010068A2 (pt) 2016-03-15

Family

ID=41478681

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1010068A BRPI1010068A2 (pt) 2009-07-24 2010-07-23 "sistema agitador, dispositivo, método para cultivo de células animais, método para produzir um polipeptídeo, uso de um sistema agitador e dispositivos para cultivar células animais"

Country Status (14)

Country Link
US (4) US20120135464A1 (pt)
EP (1) EP2456547B2 (pt)
JP (5) JP5921433B2 (pt)
KR (1) KR20120031083A (pt)
CN (1) CN102639221B (pt)
AU (1) AU2010275687A1 (pt)
BR (1) BRPI1010068A2 (pt)
CA (1) CA2766836A1 (pt)
DE (1) DE202010018640U1 (pt)
ES (1) ES2478294T5 (pt)
IL (1) IL216666A0 (pt)
MX (1) MX2012000730A (pt)
SG (1) SG177727A1 (pt)
WO (1) WO2011009625A1 (pt)

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US10076731B2 (en) 2009-06-05 2018-09-18 Hoffman-La Roche Inc. Combination stirrer
EP2456547B2 (en) * 2009-07-24 2024-03-06 F. Hoffmann-La Roche AG Stirrer system
US8619148B1 (en) 2012-01-04 2013-12-31 Audience, Inc. Image correction after combining images from multiple cameras
US10174351B2 (en) 2013-01-11 2019-01-08 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material
KR101477258B1 (ko) * 2013-05-29 2014-12-30 현대제철 주식회사 용선 교반용 임펠라의 침적 깊이 제어장치 및 제어방법
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US11944946B2 (en) 2013-06-28 2024-04-02 Saint-Gobain Performance Plastics Corporation Mixing assemblies including magnetic impellers
JP6696421B2 (ja) * 2014-06-04 2020-05-20 三菱ケミカル株式会社 トナー製造用連続式反応装置、連続式反応システム、微粒子製造方法、及び静電荷像現像用トナーの製造方法
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CN106801009A (zh) * 2015-11-25 2017-06-06 衡阳屹顺化工有限公司 一种好气发酵装置
JP6840219B2 (ja) * 2016-03-14 2021-03-10 パテル ラビンドラカマー ディラブハイＰＡＴＥＬ，Ｒａｖｉｎｄｒａｋｕｍａｒ Ｄｈｉｒｕｂｈａｉ バイオリアクタシステム及びその方法
AU2017375883B2 (en) * 2016-12-13 2023-11-23 Société des Produits Nestlé S.A. Ergonomic whisk for food processing
JP7148279B2 (ja) * 2018-05-31 2022-10-05 花王株式会社 撹拌方法及び撹拌装置
US20200330936A1 (en) * 2018-10-05 2020-10-22 University Of Baltimore Systems, Methods, and Apparatus for Utilizing a Resuspension Tank
RU2737205C1 (ru) * 2020-02-18 2020-11-26 Федеральное государственное бюджетное образовательное учреждение высшего образования "Арктический государственный агротехнологический университет" (ФГБОУ ВО Арктический ГАТУ) Аппарат для культивирования микроорганизмов
CN111570489B (zh) * 2020-06-22 2021-04-27 山东润德生物科技有限公司 一种好氧发酵过程的物料补料装置
CN111760542A (zh) * 2020-06-23 2020-10-13 武汉工程大学 一种化妆品膏状反应釜
CN115591426A (zh) * 2022-11-10 2023-01-13 江苏碧诺环保科技有限公司（Cn） 一种全自动加药装置的剪切叶片搅拌器
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CN120464491A (zh) * 2025-05-27 2025-08-12 安及义实业（上海）有限公司 水翼形式生物反应器

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Also Published As

Publication number Publication date
JP6505592B2 (ja) 2019-04-24
CA2766836A1 (en) 2011-01-27
SG177727A1 (en) 2012-02-28
EP2456547B1 (en) 2014-06-04
US20180187138A1 (en) 2018-07-05
IL216666A0 (en) 2012-02-29
CN102639221B (zh) 2014-12-10
JP5921433B2 (ja) 2016-05-24
JP2017209676A (ja) 2017-11-30
JP2021007946A (ja) 2021-01-28
JP6827389B2 (ja) 2021-02-10
JP2016073976A (ja) 2016-05-12
WO2011009625A1 (en) 2011-01-27
US20150175952A1 (en) 2015-06-25
US20120135464A1 (en) 2012-05-31
ES2478294T5 (es) 2024-08-02
DE202010018640U1 (de) 2019-11-14
US20240384214A1 (en) 2024-11-21
ES2478294T3 (es) 2014-07-21
MX2012000730A (es) 2012-01-27
AU2010275687A1 (en) 2012-01-12
JP2012533419A (ja) 2012-12-27
KR20120031083A (ko) 2012-03-29
JP2014140378A (ja) 2014-08-07
EP2456547A1 (en) 2012-05-30
CN102639221A (zh) 2012-08-15
EP2456547B2 (en) 2024-03-06

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