BRPI1010239A2 - endoglucanases aprimoradas, derivados e seus usos - Google Patents

endoglucanases aprimoradas, derivados e seus usos

Info

Publication number
BRPI1010239A2
BRPI1010239A2 BRPI1010239A BRPI1010239A BRPI1010239A2 BR PI1010239 A2 BRPI1010239 A2 BR PI1010239A2 BR PI1010239 A BRPI1010239 A BR PI1010239A BR PI1010239 A BRPI1010239 A BR PI1010239A BR PI1010239 A2 BRPI1010239 A2 BR PI1010239A2
Authority
BR
Brazil
Prior art keywords
derivatives
endoglucanases
improved
improved endoglucanases
Prior art date
Application number
BRPI1010239A
Other languages
English (en)
Inventor
Andrew Shaw
Ish Kumar Dhawan
Jie Yang
Kripa Rao
Onorato Campopiano
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of BRPI1010239A2 publication Critical patent/BRPI1010239A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI1010239A 2009-03-31 2010-03-31 endoglucanases aprimoradas, derivados e seus usos BRPI1010239A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16531209P 2009-03-31 2009-03-31
PCT/US2010/029509 WO2010120557A1 (en) 2009-03-31 2010-03-31 Improved endoglucanases

Publications (1)

Publication Number Publication Date
BRPI1010239A2 true BRPI1010239A2 (pt) 2016-10-11

Family

ID=42981280

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1010239A BRPI1010239A2 (pt) 2009-03-31 2010-03-31 endoglucanases aprimoradas, derivados e seus usos

Country Status (6)

Country Link
US (3) US8088608B2 (pt)
EP (1) EP2414506B1 (pt)
CN (1) CN102428170B (pt)
BR (1) BRPI1010239A2 (pt)
CA (1) CA2757040C (pt)
WO (1) WO2010120557A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2780974C (en) * 2009-11-20 2016-02-02 Codexis, Inc. Mutli-cellulase enzyme compositions for hydrolysis of cellulosic biomass
US8759064B2 (en) 2010-05-14 2014-06-24 Codexis, Inc. Cellobiohydrolase variants
CA2807702C (en) 2010-08-20 2018-07-24 Codexis, Inc. Use of glycoside hydrolase 61 family proteins in processing of cellulose
WO2012061517A1 (en) 2010-11-02 2012-05-10 Novozymes, Inc. Methods of pretreating cellulosic material with a gh61 polypeptide
AR085379A1 (es) * 2011-02-23 2013-09-25 Syngenta Participations Ag Potenciacion de sacarificacion enzimatica
EP2748317B1 (en) 2011-08-22 2017-04-19 Codexis, Inc. Gh61 glycoside hydrolase protein variants and cofactors that enhance gh61 activity
US8945903B2 (en) 2011-08-23 2015-02-03 Codexis, Inc. Cellobiohydrolase variants
BR112014015030A2 (pt) 2011-12-20 2017-06-13 Codexis Inc variantes da endoflucanase 1b (eg1b)
US8980578B2 (en) 2012-06-11 2015-03-17 Codexis, Inc. Fungal beta-xylosidase variants
CN102888418B (zh) * 2012-11-01 2013-10-09 广西大学 链霉菌的内切葡聚糖酶基因Cel5B及其应用
US8778639B1 (en) 2013-02-12 2014-07-15 Novozymes Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US8771993B1 (en) * 2013-02-12 2014-07-08 Novozymes A/S Polypeptides having endoglucanse activity and polynucleotides encoding same
CN111699252B (zh) * 2019-01-16 2024-04-30 福尼亚生物处理股份有限公司 内切葡聚糖酶组合物和方法
CN110373344B (zh) * 2019-04-29 2022-07-29 广西科学院 鲤链霉菌及其应用
CN113234635B (zh) * 2021-05-31 2022-09-16 元和生物科技(德州)有限公司 一种用于防治辣椒立枯病的复合微生物菌剂

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5839517B2 (ja) 1974-09-20 1983-08-30 カブシキガイシヤ バイオリサ−チセンタ− セルロ−スカラ アルコ−ルオセイゾウスル ホウホウ
US3990945A (en) 1975-04-28 1976-11-09 Bio Research Center Company Limited Enzymatic hydrolysis of cellulose
DE3009104C2 (de) 1980-03-10 1990-10-04 Odenwald-Chemie GmbH, 6901 Schönau Verwendung eines Epoxydharzes zur Herstellung von feuerhemmenden Schichten oder Überzügen und Verfahren zur Herstellung derselben
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US6335160B1 (en) * 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6117679A (en) * 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5834252A (en) 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
FI964808A0 (fi) 1994-06-03 1996-12-02 Novo Nordisk Biotech Inc Puhdistetut Myceliophthora lakkaasit ja niitä koodaavat nukleiinihapot
CN101659926A (zh) 1994-06-30 2010-03-03 诺沃奇梅兹有限公司 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子
CN102080070B (zh) * 1995-03-17 2016-01-20 诺沃奇梅兹有限公司 新的内切葡聚糖酶
FI104465B (fi) 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
US7883872B2 (en) 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
US5811381A (en) 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
US6537746B2 (en) 1997-12-08 2003-03-25 Maxygen, Inc. Method for creating polynucleotide and polypeptide sequences
NZ505295A (en) * 1997-12-16 2002-12-20 Genencor Int A method of identifying cellulase gene sequences using conserved amino acid sequence fragments from known cellulase enzymes to provide primer nucleotide sequences
KR100618495B1 (ko) 1998-10-06 2006-08-31 마크 아론 에말파브 섬유상의 진균성 숙주 영역에서의 형질전환 시스템:크리소스포륨속에서
JP4221100B2 (ja) 1999-01-13 2009-02-12 エルピーダメモリ株式会社 半導体装置
US6376246B1 (en) * 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7977051B2 (en) * 1999-04-10 2011-07-12 Danisco Us Inc. EGIII-like enzymes, DNA encoding such enzymes and methods for producing such enzymes
EP1272967A2 (en) 2000-03-30 2003-01-08 Maxygen, Inc. In silico cross-over site selection
US20050084907A1 (en) * 2002-03-01 2005-04-21 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
BRPI0515786A2 (pt) 2004-12-17 2011-10-11 Iogen Energy Corp reator de decantação de fluxo ascendente para hidrólise enzimática de celulose
WO2007115201A2 (en) * 2006-03-30 2007-10-11 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
CN101501205A (zh) 2006-06-22 2009-08-05 埃欧金能源公司 用于改良纤维素的酶法水解的酶组合物及其使用方法
US8017373B2 (en) 2006-08-31 2011-09-13 Iogen Energy Corporation Process for enzymatic hydrolysis of pretreated lignocellulosic feedstocks
WO2008042876A2 (en) 2006-10-02 2008-04-10 Codexis, Inc. Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor
EP2505651A3 (en) 2006-12-10 2013-01-09 Dyadic International, Inc. Isolated fungus with reduced protease activity
CA2675592A1 (en) * 2007-01-18 2008-07-24 Danisco Us, Inc., Genencor Division Modified endoglucanase ii and methods of use
WO2008148131A1 (en) * 2007-05-31 2008-12-04 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US8980599B2 (en) * 2007-08-02 2015-03-17 Iogen Energy Corporation Method for the production of alcohol from a pretreated lignocellulosic feedstock
US8551751B2 (en) 2007-09-07 2013-10-08 Dyadic International, Inc. BX11 enzymes having xylosidase activity
US7807419B2 (en) * 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
DK2188381T3 (da) 2007-08-30 2012-04-02 Iogen Energy Corp Enzymatisk hydrolyse af lignocellulosisk råmateriale med anvendelse af accessoriske enzymer
US10676751B2 (en) * 2008-02-29 2020-06-09 The Trustees Of The University Of Pennsylvania Production and use of plant degrading materials
US20090312196A1 (en) * 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
EP2200016A1 (de) 2008-12-17 2010-06-23 Goodbuy Corporation S.A. Elektroakustisches Tonabnehmersystem für ein Saiteninstrument

Also Published As

Publication number Publication date
CA2757040C (en) 2016-02-09
WO2010120557A1 (en) 2010-10-21
CN102428170B (zh) 2015-03-18
US8206960B1 (en) 2012-06-26
EP2414506A1 (en) 2012-02-08
EP2414506B1 (en) 2017-05-03
EP2414506A4 (en) 2013-08-28
US8663960B2 (en) 2014-03-04
US20100267089A1 (en) 2010-10-21
CN102428170A (zh) 2012-04-25
CA2757040A1 (en) 2010-10-21
US20120178132A1 (en) 2012-07-12
US8088608B2 (en) 2012-01-03
US20120315676A1 (en) 2012-12-13

Similar Documents

Publication Publication Date Title
BRPI1010239A2 (pt) endoglucanases aprimoradas, derivados e seus usos
BRPI1016150A2 (pt) compostos heterocíclicos e seus usos.
BR112013012132A2 (pt) composição compreendendo proteínas e oligossacarídeos hidrolisados, e seus usos
BRPI0909185A2 (pt) Derivado de vitamina e e seus usos
BRPI0910746A2 (pt) reticuladores e seus usos
BR112012000660A2 (pt) compostos heterociclos e seus usos
BR112013006272A2 (pt) compostos de piridina e seus usos
BR112012001061A2 (pt) glicosídeos 2,3-fluorados como inibidores de neuraminidase e seu uso como antivirais
BR112012002114A2 (pt) cevadas e seu usos.
PT2473527T (pt) Formulações estáveis de polipéptidos e seus usos
BRPI0921862A2 (pt) inibidores de raf e seus usos
PT3339323T (pt) Anticorpos anti-péptido beta-amilóide n3pglu e seus usos
BRPI1011801A2 (pt) membranas biométricas e seus usos.
BRPI1009372A2 (pt) compostos, composição farmacêutica e respectivos usos
PL2678035T3 (pl) Pochodne fenalen-1-onu, sposób ich wytwarzania i zastosowanie
BRPI1009420A2 (pt) axmi-001, axmi-002, axmi-030, e axmi-045; genes de toxina e métodos para seu uso
BRPI1010881A2 (pt) derivados de triazina e suas aplicações terapêuticas.
BRPI1016117A2 (pt) derivados de isoxazol-isoxazol e isoxasol-isotiazol.
HRP20160737T1 (hr) Anti-her3-protutijela i njihove uporabe
BRPI1010882A2 (pt) derivados de triazina e suas aplicações terapêuticas.
BR112012000763A2 (pt) derivados de piridin-4-ila
BRPI0908853A2 (pt) composto oligopeptídicos e seus usos
FI20086253A0 (fi) Sieniendoglukanaasit, niiden valmistus ja käyttö
BR112012000370A2 (pt) derivados de 1,2,4-tiazolidin-3-ona e seus usos no tratamento de câncer
BRPI0909097A2 (pt) derivados de isossorbida e seus usos como modificadores de flavor, realçadores de sabor e intensificadores de sabor

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL

B350 Update of information on the portal [chapter 15.35 patent gazette]