BRPI1010903A2 - partícula modificada na superfície, composição farmacêutica, método para intensificar a absorção celular de um agente ativo, uso de uma pluralidade de partículas modificadas na superfície, e, pluralidade de partículas modificadas na superfície - Google Patents

partícula modificada na superfície, composição farmacêutica, método para intensificar a absorção celular de um agente ativo, uso de uma pluralidade de partículas modificadas na superfície, e, pluralidade de partículas modificadas na superfície

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Publication number
BRPI1010903A2
BRPI1010903A2 BRPI1010903A BRPI1010903A BRPI1010903A2 BR PI1010903 A2 BRPI1010903 A2 BR PI1010903A2 BR PI1010903 A BRPI1010903 A BR PI1010903A BR PI1010903 A BRPI1010903 A BR PI1010903A BR PI1010903 A2 BRPI1010903 A2 BR PI1010903A2
Authority
BR
Brazil
Prior art keywords
surface modified
modified particles
pharmaceutical composition
active agent
particles
Prior art date
Application number
BRPI1010903A
Other languages
English (en)
Inventor
Barrett Rabinow
Jane Werling
Mahesh V Chaubal
Sarah Lee
Shawn F Bairstow
Original Assignee
Baxter Healthcare Sa
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare Sa, Baxter Int filed Critical Baxter Healthcare Sa
Publication of BRPI1010903A2 publication Critical patent/BRPI1010903A2/pt

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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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WO2010132664A1 (en) 2010-11-18
EP2429493B1 (en) 2014-07-23
JP2012526843A (ja) 2012-11-01
MX2011012196A (es) 2013-05-30
CN102458369B (zh) 2014-12-03
EP2429493A1 (en) 2012-03-21
US20100290983A1 (en) 2010-11-18
IL216374A (en) 2017-11-30
AU2010249008A1 (en) 2011-12-01
SG176055A1 (en) 2011-12-29
US20210251900A1 (en) 2021-08-19
US10952965B2 (en) 2021-03-23
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AU2010249008B2 (en) 2014-06-05

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