BRPI1011245A2 - niacina e/ou trigonelina como um estimulante muscular - Google Patents

niacina e/ou trigonelina como um estimulante muscular

Info

Publication number
BRPI1011245A2
BRPI1011245A2 BRPI1011245A BRPI1011245A BRPI1011245A2 BR PI1011245 A2 BRPI1011245 A2 BR PI1011245A2 BR PI1011245 A BRPI1011245 A BR PI1011245A BR PI1011245 A BRPI1011245 A BR PI1011245A BR PI1011245 A2 BRPI1011245 A2 BR PI1011245A2
Authority
BR
Brazil
Prior art keywords
trigonelin
niacin
muscle stimulant
stimulant
muscle
Prior art date
Application number
BRPI1011245A
Other languages
English (en)
Inventor
Angelika Friedel
Christof Wehrli
Karin Kuratli
Karin Wertz
Swen Wolfram
Ying Wang-Schmidt
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP09162470A external-priority patent/EP2269607A1/en
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of BRPI1011245A2 publication Critical patent/BRPI1011245A2/pt
Publication of BRPI1011245B1 publication Critical patent/BRPI1011245B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/742—Coffea, e.g. coffee
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/316—Foods, ingredients or supplements having a functional effect on health having an effect on regeneration or building of ligaments or muscles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pediatric Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1011245-6A 2009-06-11 2010-06-10 Uso de trigonelina como um estimulante muscular. BRPI1011245B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09162470A EP2269607A1 (en) 2009-06-11 2009-06-11 Trigonelline as a muscle stimulant
EP09162470.0 2009-06-11
EP09166271 2009-07-23
EP09166271.8 2009-07-23
PCT/EP2010/058124 WO2010142750A1 (en) 2009-06-11 2010-06-10 Niacin and/or trigonelline as a muscle stimulant

Publications (2)

Publication Number Publication Date
BRPI1011245A2 true BRPI1011245A2 (pt) 2016-03-22
BRPI1011245B1 BRPI1011245B1 (pt) 2020-03-24

Family

ID=42372994

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1011245-6A BRPI1011245B1 (pt) 2009-06-11 2010-06-10 Uso de trigonelina como um estimulante muscular.

Country Status (10)

Country Link
US (4) US8772230B2 (pt)
EP (1) EP2440206B1 (pt)
JP (1) JP5910495B2 (pt)
KR (1) KR101810698B1 (pt)
CN (1) CN102802626B (pt)
BR (1) BRPI1011245B1 (pt)
DK (1) DK2440206T3 (pt)
ES (1) ES2688424T3 (pt)
PL (1) PL2440206T3 (pt)
WO (1) WO2010142750A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5593550B2 (ja) * 2008-02-13 2014-09-24 ディーエスエム アイピー アセッツ ビー．ブイ． ヒトの筋生理に影響を与えるための２５−ヒドロキシビタミンｄ３の使用
ES2688424T3 (es) 2009-06-11 2018-11-02 Dsm Ip Assets B.V. Trigonelina como estimulante muscular
US9889222B2 (en) 2011-11-09 2018-02-13 Kimberly-Clark Worldwide, Inc. Aqueous medium-sensitive coating compositions for triggered release of active ingredients and visual indication for wetness
US9585826B2 (en) 2012-11-07 2017-03-07 Kimberly-Clark Worldwide, Inc. Triggerable compositions for two-stage, controlled release of active chemistry
US9119780B2 (en) 2013-10-30 2015-09-01 Kimberly-Clark Worldwide, Inc. Triggerable compositions for two-stage, controlled release of proactive chemistry
US11666561B2 (en) 2017-06-01 2023-06-06 Aarhus Universitet Compounds for use in regulating follicle maturation
CN108014109B (zh) * 2017-12-27 2019-09-20 浙江科技学院 葫芦巴碱在制备治疗或预防缺氧性损伤的药物或食品中的应用
CN111727038B (zh) * 2018-01-17 2025-05-13 南安普顿大学 肌肉减少症和nad缺乏的风险预测及分级方法
US12551472B2 (en) 2019-07-05 2026-02-17 Societe Des Produits Nestle S.A. Compositions and methods using trigonelline to produce intracellular nicotinamide adenine dinucleotide (NAD+) for treating or preventing physiological disorders or states
US20220249462A1 (en) * 2019-07-05 2022-08-11 Societe Des Produits Nestle S.A. Compositions and methods using trigonelline to produce intracellular nad+
EP3993791A1 (en) * 2019-07-05 2022-05-11 Société des Produits Nestlé S.A. Compositions and methods using trigonelline and vitamins for preventing or treating conditions or disorders in skeletal muscle
US20220265625A1 (en) * 2019-07-05 2022-08-25 Societe Des Produits Nestle S.A. Compositions and methods using trigonelline and minerals for preventing or treating conditions or disorders in skeletal muscle
EP3993789A1 (en) * 2019-07-05 2022-05-11 Société des Produits Nestlé S.A. Compositions and methods using trigonelline and high protein for preventing or treating conditions or disorders in skeletal muscle
US20230398104A1 (en) * 2020-10-30 2023-12-14 Societe Des Produits Nestle S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for rehabilitation
JP7713217B2 (ja) * 2021-03-10 2025-07-25 国立大学法人東京海洋大学 アンジオテンシン変換酵素阻害剤、医薬組成物、及び食品
WO2024246601A1 (en) 2023-05-26 2024-12-05 Amazentis Sa Compositions comprising trigonelline and urolithin
EP4734992A1 (en) * 2023-06-29 2026-05-06 Société des Produits Nestlé S.A. Methods and compositions comprising trigonelline for treating muscle decline and a kidney dysfunction
KR102806161B1 (ko) * 2024-03-25 2025-06-13 전성문 연어알 발효물을 포함하는 근육 증강 또는 보호용 조성물
DK202430556A1 (en) 2024-09-20 2026-04-08 Dsm Ip Assets Bv Use of 3’-sialyllacto-n-tetraose, 6’-sialyllacto-n-neotetraose and/or 3’-sialyl-3-fucosyllactose

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
IT1317008B1 (it) * 2000-04-04 2003-05-26 Sigma Tau Healthscience Spa Integratore alimentare energizzante sulla muscolatura scheletrica eprotettivo sull'apparato cardiovascolare.
US20050176827A1 (en) * 2002-05-10 2005-08-11 Lee Steve S. Compositions and methods for glycogen synthesis
CN100361599C (zh) * 2002-10-23 2008-01-16 克尔塞根控股有限公司 抗氧化组合物
JP2006507283A (ja) * 2002-10-23 2006-03-02 クエルセジーン ホールディングス エルエルシー 抗酸化組成物
JP2004168704A (ja) 2002-11-20 2004-06-17 Otsuka Pharmaceut Co Ltd 筋肉増加用製剤
EP1604671A4 (en) * 2003-02-26 2006-03-29 Kyowa Hakko Kogyo Kk MUSCLE TREATMENT AND MEANS FOR PREVENTING OR TREATING MUSCLE WEAKNESS
JP4641942B2 (ja) * 2003-10-03 2011-03-02 フェーイレン・ナムローゼ・フェンノートシャップ ヒトおよび動物におけるｉｇｆ−１血清レベルの低下と関連した種々の疾患状態の治療用の治療用組成物の製造のための血清中ｉｇｆ−１レベルを増加できる化合物の使用
US20070160698A1 (en) 2004-02-10 2007-07-12 Toshiaki Waga Muscular strength enhancing agent
US20050226948A1 (en) 2004-03-02 2005-10-13 Lee Steve S Methods for enhancing the transport of glucose into muscle
US20050233014A1 (en) * 2004-03-02 2005-10-20 Lee Steve S Methods for affecting homeostasis and metabolism in a mammalian body
WO2006096996A1 (en) * 2005-03-18 2006-09-21 Ripped Formulations Ltd. Compositions and methods for increasing metabolism, thermogenesis and/or muscular definition
CN101257897A (zh) * 2005-07-07 2008-09-03 西特里斯药业公司 用于治疗或预防肥胖、胰岛素抵抗障碍和线粒体相关障碍的方法和相关组合物
RU2420210C2 (ru) * 2006-03-23 2011-06-10 Нестек С.А. Высококалорийная питательная добавка
DE202006019504U1 (de) 2006-12-21 2007-03-29 Weber & Weber Gmbh & Co. Kg Eiweißpräparat
US20080199517A1 (en) 2007-02-19 2008-08-21 Indus Biotech Private Ltd Composition and a process thereof
CA2679206C (en) * 2007-03-05 2015-02-24 Indus Biotech Private Limited Pharmaceutical compositions comprising trigonelline and 4-hydroxyisoleucine and a process thereof
PL2173356T5 (pl) * 2007-08-07 2018-11-30 Dsm Ip Assets B.V. Stosowanie 25-hydroksywitaminy d3 do zwiększania masy mięśniowej u ssaków
US20090156634A1 (en) * 2007-12-12 2009-06-18 Iovate T. & P. Inc. Tropane alkaloids and trigonelline combinations and methods for administering the same
WO2009073942A1 (en) * 2007-12-12 2009-06-18 Iovate T. & P. Inc. Tropane alkaloids and trigonelline combinations and methods for administering the same
ES2688424T3 (es) 2009-06-11 2018-11-02 Dsm Ip Assets B.V. Trigonelina como estimulante muscular

Also Published As

Publication number Publication date
US8772230B2 (en) 2014-07-08
US9241938B2 (en) 2016-01-26
JP5910495B2 (ja) 2016-04-27
US20110142974A1 (en) 2011-06-16
KR101810698B1 (ko) 2018-01-25
KR20120036963A (ko) 2012-04-18
PL2440206T3 (pl) 2018-12-31
EP2440206A1 (en) 2012-04-18
EP2440206B1 (en) 2018-07-18
CN102802626A (zh) 2012-11-28
DK2440206T3 (en) 2018-11-05
US20120190617A1 (en) 2012-07-26
JP2012529469A (ja) 2012-11-22
CN102802626B (zh) 2015-11-25
US20130018076A1 (en) 2013-01-17
BRPI1011245B1 (pt) 2020-03-24
ES2688424T3 (es) 2018-11-02
US8323707B2 (en) 2012-12-04
WO2010142750A1 (en) 2010-12-16
US20150079206A1 (en) 2015-03-19

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/455 (2006.01), A23L 33/105 (2016.0

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/06/2010, OBSERVADAS AS CONDICOES LEGAIS.