BRPI1011489A2 - método para seleção de genes candidatos estatisticamente validados. - Google Patents

método para seleção de genes candidatos estatisticamente validados.

Info

Publication number
BRPI1011489A2
BRPI1011489A2 BRPI1011489A BRPI1011489A BRPI1011489A2 BR PI1011489 A2 BRPI1011489 A2 BR PI1011489A2 BR PI1011489 A BRPI1011489 A BR PI1011489A BR PI1011489 A BRPI1011489 A BR PI1011489A BR PI1011489 A2 BRPI1011489 A2 BR PI1011489A2
Authority
BR
Brazil
Prior art keywords
selection
candidate genes
statistically validated
validated candidate
statistically
Prior art date
Application number
BRPI1011489A
Other languages
English (en)
Inventor
Daolong Wang
Joseph Byrum
Joseph Dallas V Clarke
Libardo Andres Gutierrez Rojas
Min Li
Venkata Krishna Kishore
Zhigang Guo
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of BRPI1011489A2 publication Critical patent/BRPI1011489A2/pt
Publication of BRPI1011489B1 publication Critical patent/BRPI1011489B1/pt

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/02—Methods or apparatus for hybridisation; Artificial pollination ; Fertility
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/04—Processes of selection involving genotypic or phenotypic markers; Methods of using phenotypic markers for selection
    • A01H1/045—Processes of selection involving genotypic or phenotypic markers; Methods of using phenotypic markers for selection using molecular markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Artificial Intelligence (AREA)
  • Databases & Information Systems (AREA)
  • Environmental Sciences (AREA)
  • Botany (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Ecology (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI1011489-0A 2009-02-06 2010-02-05 método para seleção de genes candidatos estatisticamente validados BRPI1011489B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/367,045 2009-02-06
US12/367,045 US8170805B2 (en) 2009-02-06 2009-02-06 Method for selecting statistically validated candidate genes
PCT/US2010/023312 WO2010091248A1 (en) 2009-02-06 2010-02-05 Method for selecting statistically validated candidate genes

Publications (2)

Publication Number Publication Date
BRPI1011489A2 true BRPI1011489A2 (pt) 2016-03-22
BRPI1011489B1 BRPI1011489B1 (pt) 2021-02-17

Family

ID=42084599

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1011489-0A BRPI1011489B1 (pt) 2009-02-06 2010-02-05 método para seleção de genes candidatos estatisticamente validados

Country Status (8)

Country Link
US (1) US8170805B2 (pt)
EP (1) EP2399214B1 (pt)
CN (1) CN102369531B (pt)
AU (1) AU2010210552B2 (pt)
BR (1) BRPI1011489B1 (pt)
CA (1) CA2750225C (pt)
ES (1) ES2757827T3 (pt)
WO (1) WO2010091248A1 (pt)

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US8504579B1 (en) * 2010-04-23 2013-08-06 Crimson Corporation Filtering a data set using trees on a computing device
US20110296753A1 (en) * 2010-06-03 2011-12-08 Syngenta Participations Ag Methods and compositions for predicting unobserved phenotypes (pup)
WO2013009969A2 (en) * 2011-07-12 2013-01-17 Carnegie Mellon University Visual representations of structured association mappings
CN102492776B (zh) * 2011-12-16 2013-09-04 浙江大学 基于四交群体的遗传连锁图谱构建方法
US20160195514A1 (en) * 2013-09-03 2016-07-07 Coyne Ip Holdings, Llc Methods for Genetically Diversified Stimulus-Response Based Gene Association Studies
CN103632067B (zh) * 2013-11-07 2016-08-17 浙江大学 一种基于混合线性模型的种子数量性状位点定位方法
CN105740649B (zh) * 2016-01-22 2018-06-19 浙江大学 一种基于混合线性模型的多性状关联分析方法
CN106096327B (zh) * 2016-06-07 2018-08-17 广州麦仑信息科技有限公司 基于Torch监督式深度学习的基因性状识别方法
WO2018183746A1 (en) * 2017-03-30 2018-10-04 Monsanto Technology Llc Systems and methods for use in identifying multiple genome edits and predicting the aggregate effects of the identified genome edits
CN107142317A (zh) * 2017-06-02 2017-09-08 中国水稻研究所 一种发掘及验证具有累积效应的水稻株高等位基因的方法
CN107315922B (zh) * 2017-08-07 2020-06-23 杭州祥音医学检验实验室有限公司 计算基因型对表型额外贡献的方法及装置
CN108197435B (zh) * 2018-01-29 2022-02-25 绥化学院 一种基于标记位点基因型含有误差的多性状多区间定位方法
EP3811366A4 (en) * 2018-06-19 2022-03-23 Ancestry.com DNA, LLC FILTERING GENETIC NETWORKS TO DISCOVER POPULATIONS OF INTEREST
CN109378037B (zh) * 2018-10-31 2023-04-14 中国石油大学(华东) 基于遗传学规律的等位基因准确推断方法
CN109817281B (zh) * 2019-01-23 2022-12-23 湖南农业大学 基因组品种构成的估计方法、装置及电子设备
CN109680078A (zh) * 2019-02-22 2019-04-26 华中农业大学 利用snp位点选择信号梯度变化指数评估经济性状候选基因的方法
CN109694924A (zh) * 2019-03-07 2019-04-30 山东省花生研究所 一种有效锚定花生数量性状候选基因区域的方法
WO2020197891A1 (en) 2019-03-28 2020-10-01 Monsanto Technology Llc Methods and systems for use in implementing resources in plant breeding
CN110010203B (zh) * 2019-03-29 2022-05-27 广州基迪奥生物科技有限公司 一种基于生物云平台的交互式动态qtl分析系统及方法
CN110459265B (zh) * 2019-08-14 2022-07-05 中国农业科学院作物科学研究所 一种提高全基因组预测准确性的方法
US11636951B2 (en) 2019-10-02 2023-04-25 Kpn Innovations, Llc. Systems and methods for generating a genotypic causal model of a disease state
CN111199773B (zh) * 2020-01-20 2023-03-28 中国农业科学院北京畜牧兽医研究所 一种精细定位性状关联基因组纯合片段的评估方法
CN111613271B (zh) * 2020-04-26 2023-02-14 西南大学 一种预测畜禽数量性状显性遗传效应的方法及应用
CN111883205B (zh) * 2020-07-14 2023-10-20 云南省烟草农业科学研究院 一种基于全基因组选择烟草有害成分预测方法及应用
CN111863127B (zh) * 2020-07-17 2023-06-16 北京林业大学 一种构建植物转录因子对靶基因遗传调控网络的方法
CN113066530B (zh) * 2021-03-31 2024-05-10 江苏省农业科学院 一种批量合并eQTL分析结果中存在连锁不平衡SNP的方法
CN114637712B (zh) * 2022-03-18 2023-03-10 无锡众星微系统技术有限公司 一种EDFB模式下SAS2SATA Bridge的错误处理方法和装置
CN114898809B (zh) * 2022-04-11 2022-12-23 中国科学院数学与系统科学研究院 适用复杂性状的基因-环境交互的分析方法及存储介质
CN114724635B (zh) * 2022-05-10 2024-12-03 华中农业大学 玉米目标qtl区间内目标基因的挖掘方法及系统
CN116052771B (zh) * 2023-01-13 2026-01-13 上海中科荃银分子育种技术有限公司 一种水稻数量性状基因快速发掘的方法
DE102023105888A1 (de) 2023-03-09 2024-09-12 KWS SAAT SE & Co. KGaA Verfahren zur Identifizierung eines Kandidaten, nämlich eines Genlocus und/oder einer Sequenzvariante, der für mindestens ein (phänotypisches) Merkmal indikativ ist
CN116564410A (zh) * 2023-05-23 2023-08-08 浙江大学 一种预测突变位点顺式调控基因的方法、设备和介质
CN116756510B (zh) * 2023-06-30 2025-09-30 北京大学 可控制样本中亲缘相关性的分析方法、系统及储存介质
CN117116355B (zh) * 2023-08-30 2024-02-20 中国农业科学院农业信息研究所 一种优异多效基因的挖掘方法、装置、设备及介质
CN118485010B (zh) * 2024-07-16 2024-09-06 湘潭大学 一种基于嵌套式多种群分类遗传算法的图形排样方法
CN119851766B (zh) * 2024-12-26 2025-07-29 中国林业科学研究院亚热带林业研究所 一种板栗基因组snp多态性与重要性状关联分析系统及其方法
CN119832979B (zh) * 2025-01-14 2025-07-08 中国科学院遗传与发育生物学研究所 基于ems群体的基因水平全基因组关联分析算法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5569588A (en) * 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
WO2001088086A2 (en) * 2000-04-19 2001-11-22 Multiqtl Ltd. System and method for mapping of multiple trait complexes in multiple environments
US20060111849A1 (en) * 2002-08-02 2006-05-25 Schadt Eric E Computer systems and methods that use clinical and expression quantitative trait loci to associate genes with traits
US8843356B2 (en) * 2002-12-27 2014-09-23 Merck Sharp & Dohme Corp. Computer systems and methods for associating genes with traits using cross species data
CN1434131A (zh) * 2003-02-20 2003-08-06 邓红文 IL－6基因中与中国人群腰椎骨密度连锁的BsrBI分子标记

Also Published As

Publication number Publication date
US8170805B2 (en) 2012-05-01
EP2399214A1 (en) 2011-12-28
CN102369531A (zh) 2012-03-07
CN102369531B (zh) 2015-03-18
CA2750225A1 (en) 2010-08-12
CA2750225C (en) 2017-05-16
AU2010210552A1 (en) 2011-08-11
EP2399214B1 (en) 2019-09-11
US20100204921A1 (en) 2010-08-12
BRPI1011489B1 (pt) 2021-02-17
WO2010091248A1 (en) 2010-08-12
ES2757827T3 (es) 2020-04-30
AU2010210552B2 (en) 2016-01-28

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/02/2021, OBSERVADAS AS CONDICOES LEGAIS.

B25G Requested change of headquarter approved

Owner name: SYNGENTA PARTICIPATIONS AG (CH)

B25A Requested transfer of rights approved

Owner name: SYNGENTA CROP PROTECTION AG (CH)