BRPI1012077B8 - composição nutricional compreendendo uma combinação de uma fonte de leucina e uma fonte de ácido graxo poli-insaturado o-3, carboidratos digeríveis e fibra dietética solúvel - Google Patents
composição nutricional compreendendo uma combinação de uma fonte de leucina e uma fonte de ácido graxo poli-insaturado o-3, carboidratos digeríveis e fibra dietética solúvelInfo
- Publication number
- BRPI1012077B8 BRPI1012077B8 BRPI1012077A BRPI1012077A BRPI1012077B8 BR PI1012077 B8 BRPI1012077 B8 BR PI1012077B8 BR PI1012077 A BRPI1012077 A BR PI1012077A BR PI1012077 A BRPI1012077 A BR PI1012077A BR PI1012077 B8 BRPI1012077 B8 BR PI1012077B8
- Authority
- BR
- Brazil
- Prior art keywords
- source
- combination
- fatty acid
- leucine
- nutritional composition
- Prior art date
Links
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 title abstract 4
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 235000016709 nutrition Nutrition 0.000 title abstract 2
- 235000014633 carbohydrates Nutrition 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 title 1
- 235000013325 dietary fiber Nutrition 0.000 title 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 2
- 230000033228 biological regulation Effects 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 230000004094 calcium homeostasis Effects 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000002417 nutraceutical Substances 0.000 abstract 1
- 235000021436 nutraceutical agent Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NLPCT/NL2009/050297 | 2009-05-27 | ||
| PCT/NL2009/050297 WO2010137944A1 (en) | 2009-05-27 | 2009-05-27 | Treatment of hypercalcaemia |
| PCT/NL2010/050319 WO2010137979A2 (en) | 2009-05-27 | 2010-05-27 | Hypercalcaemia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI1012077A2 BRPI1012077A2 (pt) | 2018-03-20 |
| BRPI1012077B1 BRPI1012077B1 (pt) | 2021-05-18 |
| BRPI1012077B8 true BRPI1012077B8 (pt) | 2022-09-20 |
Family
ID=41397536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1012077A BRPI1012077B8 (pt) | 2009-05-27 | 2010-05-27 | composição nutricional compreendendo uma combinação de uma fonte de leucina e uma fonte de ácido graxo poli-insaturado o-3, carboidratos digeríveis e fibra dietética solúvel |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20120122785A1 (pt) |
| EP (2) | EP2435039B2 (pt) |
| CN (2) | CN102458390B (pt) |
| BR (1) | BRPI1012077B8 (pt) |
| DK (1) | DK2435039T4 (pt) |
| ES (1) | ES2555860T5 (pt) |
| HU (1) | HUE028295T2 (pt) |
| MX (1) | MX2011012573A (pt) |
| PL (1) | PL2435039T5 (pt) |
| PT (1) | PT2435039E (pt) |
| RU (1) | RU2555359C2 (pt) |
| WO (2) | WO2010137944A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TN2010000251A1 (fr) * | 2010-06-03 | 2011-11-11 | Rekik Raouf | N-acetyl-dl-leucine medicament neuro et retino protecteur |
| WO2012141575A1 (en) | 2011-04-14 | 2012-10-18 | N.V.Nutricia | Combination of epa, dpa and/or dha with a chemotherapeutic agent |
| JP2014511890A (ja) * | 2011-04-18 | 2014-05-19 | ネステク ソシエテ アノニム | α−HICA及びα−ケトグルタル酸を含有する栄養組成物 |
| WO2015002527A1 (en) | 2013-07-05 | 2015-01-08 | N.V. Nutricia | Amino acid composition for use in the treatment of a pdd |
| US9616292B2 (en) * | 2015-01-09 | 2017-04-11 | Nolan Orfield | Exercise tracker |
| US11197917B2 (en) | 2017-12-01 | 2021-12-14 | ByHeart, Inc. | Formulations for nutritional support in subjects in need thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05178758A (ja) * | 1991-03-22 | 1993-07-20 | Suntory Ltd | トリペプチドを有効成分とする骨疾患の予防および治療剤 |
| EP0504938A3 (en) * | 1991-03-22 | 1993-04-14 | Suntory Limited | Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient |
| JPH05140063A (ja) * | 1991-11-19 | 1993-06-08 | Suntory Ltd | ジペプチド誘導体及びそれを有効成分とする骨疾患の予防及び治療剤 |
| US6077828A (en) * | 1996-04-25 | 2000-06-20 | Abbott Laboratories | Method for the prevention and treatment of cachexia and anorexia |
| US20070037777A1 (en) * | 2005-08-12 | 2007-02-15 | Immunopath Profile, Inc. | Lipid-containing compositions and methods of using them |
| GB0003310D0 (en) | 2000-02-15 | 2000-04-05 | Univ Sheffield | Bone formation |
| NL1019368C2 (nl) | 2001-11-14 | 2003-05-20 | Nutricia Nv | Preparaat voor het verbeteren van receptorwerking. |
| US20040087490A1 (en) * | 2002-09-20 | 2004-05-06 | Troup John P. | Nutritional compositions |
| US20040171692A1 (en) * | 2003-02-28 | 2004-09-02 | Scutt Andrew | Modulation of bone formation |
| MXPA05009933A (es) | 2003-03-18 | 2005-11-04 | Novartis Ag | Composiciones que comprenden acidos grasos y aminoacidos. |
| ATE433674T1 (de) * | 2003-06-23 | 2009-07-15 | Nestec Sa | Säuglingsnährpräparat oder folgemilch |
| JP4702678B2 (ja) * | 2004-06-07 | 2011-06-15 | 環境創研株式会社 | 競走馬用飼料添加材 |
| CA2573338C (en) | 2004-07-28 | 2013-07-02 | Abbott Laboratories | A nutritional composition comprising dried fruit solids and an oligosaccharide and its use for treating osteoporosis |
| EP1800675B1 (en) | 2005-12-23 | 2011-05-18 | N.V. Nutricia | Composition comprising polyunsaturated fatty acids, proteins, manganese and/or molybden and nucleosides/nucleotides for treating dementia |
| GB0624879D0 (en) * | 2006-12-14 | 2007-01-24 | Shs Int Ltd | Treatment of pervasive development disorders |
| US20080171791A1 (en) * | 2007-01-11 | 2008-07-17 | Mdr Fitness Corp. | Compositions and Method for Losing Weight |
| US20080200425A1 (en) * | 2007-02-16 | 2008-08-21 | Kurtz Seymour J | Methods and compositions for regulating bone mineral density |
| WO2008147228A1 (en) * | 2007-05-31 | 2008-12-04 | Fonterra Corporate Research And Development Limited | Treatment or prevention of bone conditions |
| US7893067B2 (en) * | 2007-06-27 | 2011-02-22 | Medivir Ab | Cysteine protease inhibitors |
| EP2025248A1 (en) * | 2007-07-31 | 2009-02-18 | Fresenius Kabi Deutschland GmbH | Cachexia prevention supplement |
| WO2010002242A1 (en) * | 2008-07-02 | 2010-01-07 | N.V. Nutricia | Nutritional composition for improving muscle function and daily activity |
| CN101314031A (zh) * | 2008-07-14 | 2008-12-03 | 王冰 | 一种改善骨营养的制剂 |
-
2009
- 2009-05-27 WO PCT/NL2009/050297 patent/WO2010137944A1/en not_active Ceased
-
2010
- 2010-05-27 CN CN201080033424.8A patent/CN102458390B/zh active Active
- 2010-05-27 WO PCT/NL2010/050319 patent/WO2010137979A2/en not_active Ceased
- 2010-05-27 EP EP10726616.5A patent/EP2435039B2/en active Active
- 2010-05-27 US US13/322,730 patent/US20120122785A1/en not_active Abandoned
- 2010-05-27 DK DK10726616.5T patent/DK2435039T4/da active
- 2010-05-27 EP EP15184059.2A patent/EP2987485B1/en active Active
- 2010-05-27 PL PL10726616T patent/PL2435039T5/pl unknown
- 2010-05-27 CN CN201410488463.7A patent/CN104257646A/zh active Pending
- 2010-05-27 PT PT107266165T patent/PT2435039E/pt unknown
- 2010-05-27 RU RU2011152873/15A patent/RU2555359C2/ru active
- 2010-05-27 BR BRPI1012077A patent/BRPI1012077B8/pt active IP Right Grant
- 2010-05-27 MX MX2011012573A patent/MX2011012573A/es not_active Application Discontinuation
- 2010-05-27 HU HUE10726616A patent/HUE028295T2/en unknown
- 2010-05-27 ES ES10726616T patent/ES2555860T5/es active Active
-
2014
- 2014-07-25 US US14/341,106 patent/US9867796B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2555359C2 (ru) | 2015-07-10 |
| HUE028295T2 (en) | 2016-12-28 |
| WO2010137979A8 (en) | 2011-11-17 |
| BRPI1012077A2 (pt) | 2018-03-20 |
| EP2435039B2 (en) | 2019-02-27 |
| MX2011012573A (es) | 2011-12-14 |
| CN102458390B (zh) | 2014-10-29 |
| CN104257646A (zh) | 2015-01-07 |
| DK2435039T3 (en) | 2015-12-21 |
| EP2987485A1 (en) | 2016-02-24 |
| US20120122785A1 (en) | 2012-05-17 |
| BRPI1012077B1 (pt) | 2021-05-18 |
| WO2010137979A3 (en) | 2011-04-14 |
| WO2010137944A1 (en) | 2010-12-02 |
| CN102458390A (zh) | 2012-05-16 |
| WO2010137979A2 (en) | 2010-12-02 |
| ES2555860T5 (es) | 2019-07-12 |
| US9867796B2 (en) | 2018-01-16 |
| US20150018277A1 (en) | 2015-01-15 |
| EP2435039B1 (en) | 2015-09-09 |
| PT2435039E (pt) | 2016-01-08 |
| PL2435039T3 (pl) | 2016-02-29 |
| PL2435039T5 (pl) | 2019-09-30 |
| EP2987485B1 (en) | 2020-02-26 |
| ES2555860T3 (es) | 2016-01-11 |
| EP2435039A2 (en) | 2012-04-04 |
| DK2435039T4 (da) | 2019-05-06 |
| RU2011152873A (ru) | 2013-07-10 |
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Legal Events
| Date | Code | Title | Description |
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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