BRPI1013153A2 - solução de bloqueio do cateter tendo propriedades antimicrobiana e anticoagulante. - Google Patents

solução de bloqueio do cateter tendo propriedades antimicrobiana e anticoagulante.

Info

Publication number
BRPI1013153A2
BRPI1013153A2 BRPI1013153A BRPI1013153A BRPI1013153A2 BR PI1013153 A2 BRPI1013153 A2 BR PI1013153A2 BR PI1013153 A BRPI1013153 A BR PI1013153A BR PI1013153 A BRPI1013153 A BR PI1013153A BR PI1013153 A2 BRPI1013153 A2 BR PI1013153A2
Authority
BR
Brazil
Prior art keywords
antimicrobial
blocking solution
anticoagulant properties
catheter blocking
catheter
Prior art date
Application number
BRPI1013153A
Other languages
English (en)
Inventor
John J Kelley Iii
Thelma I Valdes
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Publication of BRPI1013153A2 publication Critical patent/BRPI1013153A2/pt
Publication of BRPI1013153B1 publication Critical patent/BRPI1013153B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • A61L33/0011Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0041Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04Macromolecular materials
    • A61L29/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/04Use of organic materials, e.g. acetylsalicylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06Use of macromolecular materials
    • A61L33/068Use of macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M2025/0019Cleaning catheters or the like, e.g. for reuse of the device, for avoiding replacement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0056Catheters; Hollow probes characterised by structural features provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1013153-1A 2009-06-11 2010-06-10 Solução de bloqueio de cateter, seringa pré- carregada, cateter e método para inibir atividade microbiana e coagulação em um cateter BRPI1013153B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18617309P 2009-06-11 2009-06-11
US61/186.173 2009-06-11
US12/797.336 2010-06-09
US12/797,336 US9248093B2 (en) 2009-06-11 2010-06-09 Catheter locking solution having antimicrobial and anticoagulation properties
PCT/US2010/038127 WO2010144674A2 (en) 2009-06-11 2010-06-10 A catheter locking solution having antimicrobial and anticoagulation properties

Publications (2)

Publication Number Publication Date
BRPI1013153A2 true BRPI1013153A2 (pt) 2016-04-05
BRPI1013153B1 BRPI1013153B1 (pt) 2018-07-03

Family

ID=43307045

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1013153-1A BRPI1013153B1 (pt) 2009-06-11 2010-06-10 Solução de bloqueio de cateter, seringa pré- carregada, cateter e método para inibir atividade microbiana e coagulação em um cateter

Country Status (10)

Country Link
US (3) US9248093B2 (pt)
EP (1) EP2440261B1 (pt)
JP (1) JP5718913B2 (pt)
CN (2) CN105031742B (pt)
AU (1) AU2010258708B2 (pt)
BR (1) BRPI1013153B1 (pt)
ES (1) ES2598002T3 (pt)
MX (1) MX339787B (pt)
SG (1) SG176721A1 (pt)
WO (1) WO2010144674A2 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
US9248093B2 (en) * 2009-06-11 2016-02-02 Becton, Dickinson And Company Catheter locking solution having antimicrobial and anticoagulation properties
HUE041512T2 (hu) * 2010-03-30 2019-05-28 Helperby Therapeutics Ltd Új kombináció és alkalmazás
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
ES2797649T3 (es) 2011-07-12 2020-12-03 Icu Medical Inc Dispositivo para entrega de agente antimicrobiano en un catéter transdérmico
US9220814B2 (en) * 2011-09-29 2015-12-29 Ethicon, Inc. Broad-spectrum antimicrobial compositions based on combinations of taurolidine and protamine and medical devices containing such compositions
CA2920835A1 (en) 2013-08-20 2015-02-26 Anutra Medical, Inc. Syringe fill system and method
US10335518B2 (en) 2013-09-26 2019-07-02 Krzysztof Appelt Catheter locking formulation and method to prepare same
AU2015252808B2 (en) 2014-05-02 2019-02-21 Excelsior Medical Corporation Strip package for antiseptic cap
USD774182S1 (en) 2014-06-06 2016-12-13 Anutra Medical, Inc. Anesthetic delivery device
USD763433S1 (en) 2014-06-06 2016-08-09 Anutra Medical, Inc. Delivery system cassette
USD750768S1 (en) 2014-06-06 2016-03-01 Anutra Medical, Inc. Fluid administration syringe
WO2016182822A1 (en) 2015-05-08 2016-11-17 Icu Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
WO2016201202A1 (en) 2015-06-11 2016-12-15 Attwill Medical Solutions Inc. Medical devices, systems, and methods utilizing antithrombin-heparin compositions
DK3370794T3 (da) * 2015-11-05 2019-12-02 Univ Texas Antimikrobielle opløsninger med forbedret stabilitet
AU2017217011B2 (en) * 2016-02-12 2021-06-03 Medical Components, Inc. Catheter locking solution and catheter locking therapy
SG11201807592WA (en) * 2016-03-07 2018-10-30 Dinesh Aggarwal Broad spectrum antimicrobial & anticoagulant composition
EP4194043A1 (en) 2016-10-14 2023-06-14 ICU Medical, Inc. Sanitizing caps for medical connectors
WO2018125845A1 (en) 2016-12-27 2018-07-05 Vasonics, Llc Catheter housing
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
WO2019060697A1 (en) * 2017-09-22 2019-03-28 Becton, Dickinson And Company 4% TRISODIC CITRATE SOLUTION FOR USE AS A CATHETER LOCK SOLUTION
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
AU2019384564B2 (en) 2018-11-21 2023-11-23 Icu Medical, Inc. Antimicrobial device comprising a cap with ring and insert
JP2024500319A (ja) 2020-12-07 2024-01-09 アイシーユー・メディカル・インコーポレーテッド 腹膜透析キャップ、システム、及び方法
EP4373536A4 (en) * 2021-07-19 2025-07-23 Becton Dickinson Co 16% SODIUM CITRATE SOLUTION FOR USE AS AN ANTIMICROBIAL CATHETER LOCK SOLUTION

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3942081A1 (de) * 1989-12-20 1991-06-27 Behringwerke Ag Mittel zur verbesserung der wiederfindung von annexinen
US5334706A (en) * 1992-01-30 1994-08-02 Baxter International Administration of low dose hemoglobin to increase perfusion
US6458762B1 (en) * 1994-03-28 2002-10-01 Baxter International, Inc. Therapeutic use of hemoglobin for preserving tissue viability and reducing restenosis
US5733869A (en) * 1995-10-06 1998-03-31 Baxter International, Inc. Therapeutic administration of hemoglobin in cardiac arrest
GB9626795D0 (en) * 1996-12-23 1997-02-12 Geistlich Soehne Ag Combating infection in delivery systems
US5763412A (en) 1997-04-08 1998-06-09 Becton Dickinson And Company Film-forming composition containing chlorhexidine gluconate
US6165484A (en) * 1997-08-26 2000-12-26 Wake Forest University EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections
US6958049B1 (en) * 1998-08-25 2005-10-25 Ash Access Technology, Inc. Method of enhancing catheter patency using a citrate salt catheter lock solution
JP2002523336A (ja) * 1998-08-25 2002-07-30 アッシュ・メディカル・システムズ・インコーポレーテッド クエン酸塩カテーテルロック溶液を使用するカテーテル開存性を高める方法
US6174537B1 (en) * 1998-09-25 2001-01-16 Becton, Dickinson And Company Catheter flush solution and method for its use
AU2001231189A1 (en) * 2000-01-27 2001-08-07 Childrens Hospital Research Foundation Transdermal anesthetic and vasodilator composition and methods for topical administration
WO2001085249A1 (en) 2000-05-10 2001-11-15 Ash Medical Systems, Inc. A catheter lock solution including a photo-oxidant
DE50212229D1 (de) * 2001-02-05 2008-06-19 Roger Marcel Humbel Sicherheitsbindung
US20040092890A1 (en) * 2001-05-10 2004-05-13 Ash Stephen R. Catheter lock solution including a photo-oxidant
US20050215978A1 (en) * 2001-05-25 2005-09-29 Ash Stephen R Method of enhancing catheter patency using a citrate salt catheter lock solution
US20040034329A1 (en) * 2001-07-13 2004-02-19 Mankus Rita A Devices and methods for infusing a liquid into a catheter
US8541472B2 (en) 2001-12-05 2013-09-24 Aseptica, Inc. Antiseptic compositions, methods and systems
DE60311958T2 (de) * 2003-02-03 2007-11-08 Polaschegg, Hans-Dietrich, Dr. Zusammensetzung zur Prävention von Infektionen durch subkutane Prothesen
US20050074485A1 (en) * 2003-05-14 2005-04-07 Lipton James M. Anti-inflammatory/anti-microbial peptides for use in dialysis
US20050124970A1 (en) * 2003-12-05 2005-06-09 Medical Components, Inc. Luer cap with antibacterial property
US7696182B2 (en) * 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
US7749529B2 (en) 2005-02-08 2010-07-06 Ash Access Technology, Inc. Catheter lock solution comprising citrate and a paraben
US20090068247A1 (en) * 2007-09-12 2009-03-12 Mucosal Therapeutics Biocompatible devices coated with a tribonectin and methods for their production
GB0722349D0 (en) 2007-11-15 2007-12-27 Reckitt Benckiser Healthcare Use of anti-bacterial compounds having an anaesthetic effect
US9248093B2 (en) * 2009-06-11 2016-02-02 Becton, Dickinson And Company Catheter locking solution having antimicrobial and anticoagulation properties

Also Published As

Publication number Publication date
US9744273B2 (en) 2017-08-29
ES2598002T3 (es) 2017-01-24
EP2440261B1 (en) 2016-08-24
US20170319757A1 (en) 2017-11-09
SG176721A1 (en) 2012-01-30
MX339787B (es) 2016-06-03
CN102802688A (zh) 2012-11-28
AU2010258708A1 (en) 2012-01-12
JP2012529356A (ja) 2012-11-22
US10350334B2 (en) 2019-07-16
JP5718913B2 (ja) 2015-05-13
CN105031742B (zh) 2018-06-01
WO2010144674A3 (en) 2011-03-31
US9248093B2 (en) 2016-02-02
MX2011013316A (es) 2012-01-30
EP2440261A2 (en) 2012-04-18
CN102802688B (zh) 2015-09-02
AU2010258708B2 (en) 2013-05-02
WO2010144674A2 (en) 2010-12-16
US20160101223A1 (en) 2016-04-14
US20100318040A1 (en) 2010-12-16
CN105031742A (zh) 2015-11-11
BRPI1013153B1 (pt) 2018-07-03

Similar Documents

Publication Publication Date Title
BRPI0921919A2 (pt) dispositivos médicos, aparelhos, sistemas e métodos
FR2921499B1 (fr) Structure orientable de type catheter ou endoscope
BRPI0912284A2 (pt) Polímeros antimicrobianos e seus usos
BR112012004695A2 (pt) curativos médicos antimicrobianos e proteção de feridas e locais de cateter
EP2429609A4 (en) CATHETER INTRODUCTION STERILIZATION
BRPI0911004A2 (pt) Artigo antimicrobiano, líquido de tratamento e métodos de preparação dos mesmos
BRPI1012598A2 (pt) Prendedor cego com característica de anti- rotação integrada, sistemas e métodos
BRPI0817288A2 (pt) Dispositivos vasculares trançados não tendo grampos de extremidade.
BR112012008367A2 (pt) sistemas e métodos de tratamento de águas residuais.
BRPI1010881A2 (pt) derivados de triazina e suas aplicações terapêuticas.
HRP20180497T1 (hr) Antimikrobni pripravci i odgovarajući postupci njihove upotrebe
BRPI1010882A2 (pt) derivados de triazina e suas aplicações terapêuticas.
BRPI1013860A2 (pt) introdutor de cateter intravenoso
BRPI0822633A2 (pt) Desinfetante, e, método de esterilização.
BRPI0820379A2 (pt) Sistemas e métodos de dispensação de produto médico
EP2138200A4 (en) SUCTION CATHETER OF A THROMBUS
BRPI0808044A2 (pt) sistemas e métodos de hemodiálise
BRPI0815773A2 (pt) composto, e, medicamento.
BRPI1007996A2 (pt) fluido de tratamento, e, método
FR2960766B1 (fr) Prothese modulaire, et kit chirurgical comprenant au moins une telle prothese modulaire
DE112008002791A5 (de) Verbesserte arzneimittelbeschichtete Medizinprodukte, deren Herstellung und Verwendung
BRPI1010311A2 (pt) conector médico, seu método para ativação e conector médico de luer macho fechado.
EP2621412A4 (en) SURGICAL IMPLANT WITH GUIDE RAIL
SG176721A1 (en) A catheter locking solution having antimicrobial and anticoagulation properties
BRPI1007015A2 (pt) implante auto-cortante e auto-limpante.

Legal Events

Date Code Title Description
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]