BRPI0815773A2 - composto, e, medicamento. - Google Patents
composto, e, medicamento.Info
- Publication number
- BRPI0815773A2 BRPI0815773A2 BRPI0815773A BRPI0815773A BRPI0815773A2 BR PI0815773 A2 BRPI0815773 A2 BR PI0815773A2 BR PI0815773 A BRPI0815773 A BR PI0815773A BR PI0815773 A BRPI0815773 A BR PI0815773A BR PI0815773 A2 BRPI0815773 A2 BR PI0815773A2
- Authority
- BR
- Brazil
- Prior art keywords
- medicine
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007225045 | 2007-08-31 | ||
| JP2008020009 | 2008-01-31 | ||
| JP2008123057 | 2008-05-09 | ||
| PCT/JP2008/065365 WO2009028588A1 (ja) | 2007-08-31 | 2008-08-28 | 多環式化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0815773A2 true BRPI0815773A2 (pt) | 2019-09-24 |
Family
ID=40387302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0815773A BRPI0815773A2 (pt) | 2007-08-31 | 2008-08-28 | composto, e, medicamento. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US9453000B2 (pt) |
| EP (2) | EP2559693B1 (pt) |
| JP (1) | JP5433418B2 (pt) |
| KR (1) | KR20100055456A (pt) |
| CN (1) | CN101815713B (pt) |
| AR (1) | AR068121A1 (pt) |
| AU (1) | AU2008292390B2 (pt) |
| BR (1) | BRPI0815773A2 (pt) |
| CA (1) | CA2694401C (pt) |
| CL (1) | CL2008002542A1 (pt) |
| ES (1) | ES2529648T3 (pt) |
| IL (1) | IL203778A (pt) |
| MX (1) | MX2010002098A (pt) |
| MY (1) | MY150507A (pt) |
| NZ (1) | NZ583515A (pt) |
| PE (1) | PE20090674A1 (pt) |
| TW (1) | TW200916469A (pt) |
| WO (1) | WO2009028588A1 (pt) |
| ZA (1) | ZA201000474B (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| US7935815B2 (en) * | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
| US20090124651A1 (en) * | 2007-08-31 | 2009-05-14 | H. Lundbeck A/S | Catecholamine derivatives and prodrugs thereof |
| BRPI0815773A2 (pt) | 2007-08-31 | 2019-09-24 | Eisai R&D Man Co Ltd | composto, e, medicamento. |
| BRPI0917144A2 (pt) * | 2008-08-27 | 2015-08-04 | Eisai R&D Man Co Ltd | Processo para preparar compostos, processo para preparar uma mistura, sais de d-dbta, de d-dpta e de ácido (+) -n- (1-feniletila) ftalâmico ((+) -pepa), e, composto. |
| LT2889033T (lt) | 2008-11-19 | 2018-07-10 | Forum Pharmaceuticals Inc. | Šizofrenijos negatyvių simptomų gydymas (r)-7-chlor-n-(chinuklidin-3-il)benzo[b]tiofen-2-karboksamidu ir jo farmaciniu požiūriu priimtinomis druskomis |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| EP2401277A1 (en) * | 2009-02-26 | 2012-01-04 | Eisai R&D Management Co., Ltd. | Salt of tetrahydrotriazolopyridine derivative and crystal thereof |
| CA2753696A1 (en) | 2009-02-26 | 2010-09-02 | Noritaka Kitazawa | Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors |
| JP2012121809A (ja) * | 2009-02-26 | 2012-06-28 | Eisai R & D Management Co Ltd | 多環式化合物の製造法およびその中間体 |
| JP2012051805A (ja) * | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | テトラヒドロトリアゾロピリジン誘導体の製造方法 |
| CN102573839A (zh) * | 2009-05-11 | 2012-07-11 | 加利福尼亚大学董事会 | 降低泛素化蛋白水平的方法 |
| JP5808319B2 (ja) * | 2009-05-11 | 2015-11-10 | フォルム ファーマシューティカルズ、インコーポレイテッド | アセチルコリンエステラーゼ阻害剤と組み合わせた特定のα7ニコチン酸受容体を用いた認知障害の治療 |
| CA2769392A1 (en) * | 2009-07-31 | 2011-02-03 | Sandoz Ag | Method for the preparation of w-amino-alkaneamides and w-amino-alkanethioamides as well as intermediates of this method |
| EP2523949B1 (en) | 2010-01-15 | 2014-08-20 | Janssen Pharmaceuticals Inc. | Novel substituted triazole derivatives as gamma secretase modulators |
| PE20170923A1 (es) | 2010-05-17 | 2017-07-12 | Forum Pharmaceuticals Inc | Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidratado |
| CA2830027C (en) | 2011-03-31 | 2016-04-26 | Pfizer Inc. | Novel bicyclic pyridinones |
| EP3461481A1 (en) | 2012-05-08 | 2019-04-03 | Forum Pharmaceuticals Inc. | Methods of maintaining, treating or improving cognitive function |
| NZ702611A (en) | 2012-05-16 | 2016-10-28 | Cellzome Ltd | Substituted 3, 4 - dihydro - 2h - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) alzheimer’s disease |
| UA110688C2 (uk) | 2012-09-21 | 2016-01-25 | Пфайзер Інк. | Біциклічні піридинони |
| AU2013366668B2 (en) | 2012-12-20 | 2017-07-20 | Janssen Pharmaceutica Nv | Novel tricyclic 3,4-dihydro-2H-pyrido[1,2-alpha]pyrazine -1,6-dione derivatives as gamma secretase modulators |
| ES2612215T3 (es) | 2013-01-17 | 2017-05-12 | Janssen Pharmaceutica, N.V. | Novedosos derivados de pirido-piperazinona sustituidos como moduladores de gamma secretasa |
| US10372396B2 (en) * | 2013-02-21 | 2019-08-06 | Lenovo ( Singapore) Pte. Ltd. | Discovery and connection to wireless displays |
| US10562897B2 (en) | 2014-01-16 | 2020-02-18 | Janssen Pharmaceutica Nv | Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators |
| MX368391B (es) | 2015-02-03 | 2019-09-30 | Pfizer | Ciclopropabenzofuranil-piridopirazindionas novedosas. |
| KR20240036128A (ko) * | 2017-06-02 | 2024-03-19 | 엑스에리스 파머수티클스, 인크. | 침전 방지 저분자 약물 제제 |
| CA3086668A1 (en) * | 2018-02-05 | 2019-08-08 | Universite De Strasbourg | Compounds and compositions for the treatment of pain |
| EP3920921A4 (en) * | 2019-02-07 | 2022-11-02 | Alsatech, Inc. | POLYVALENT EMOXYPIN DERIVATIVES |
| CN120712258A (zh) * | 2022-12-15 | 2025-09-26 | 西特瑞治疗有限公司 | 用于治疗或预防炎性疾病或与不良免疫反应相关的疾病的取代吡啶类化合物 |
| CN118459425B (zh) * | 2024-04-29 | 2025-11-14 | 南通华祥医药科技有限公司 | 一种吡咯烷-1-胺-二盐酸盐的制备方法 |
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| KR101138045B1 (ko) | 2007-05-11 | 2012-04-24 | 에프. 호프만-라 로슈 아게 | 아밀로이드 베타에 대한 조절제로서의 헤트아릴아닐린 |
| EP2166854A4 (en) | 2007-06-13 | 2012-05-16 | Merck Sharp & Dohme | TRIAZONE DERIVATIVES FOR THE TREATMENT OF MORBUS ALZHEIMER AND RELATED SUFFERINGS |
| CA2695543A1 (en) | 2007-08-06 | 2009-02-12 | Schering Corporation | Gamma secretase modulators |
| US7935815B2 (en) | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
| BRPI0815773A2 (pt) | 2007-08-31 | 2019-09-24 | Eisai R&D Man Co Ltd | composto, e, medicamento. |
| US8450343B2 (en) | 2007-12-06 | 2013-05-28 | Xianhai Huang | Gamma secretase modulators |
| US20110086850A1 (en) * | 2008-04-11 | 2011-04-14 | Board Of Regents, The University Of Texas System | Radiosensitization of tumors with indazolpyrrolotriazines for radiotherapy |
| BRPI0917144A2 (pt) | 2008-08-27 | 2015-08-04 | Eisai R&D Man Co Ltd | Processo para preparar compostos, processo para preparar uma mistura, sais de d-dbta, de d-dpta e de ácido (+) -n- (1-feniletila) ftalâmico ((+) -pepa), e, composto. |
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| JP2012051806A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
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| US8381014B2 (en) * | 2010-05-06 | 2013-02-19 | International Business Machines Corporation | Node controller first failure error management for a distributed system |
-
2008
- 2008-08-28 BR BRPI0815773A patent/BRPI0815773A2/pt not_active IP Right Cessation
- 2008-08-28 EP EP12191398.2A patent/EP2559693B1/en active Active
- 2008-08-28 US US12/671,873 patent/US9453000B2/en not_active Expired - Fee Related
- 2008-08-28 TW TW097132893A patent/TW200916469A/zh unknown
- 2008-08-28 WO PCT/JP2008/065365 patent/WO2009028588A1/ja not_active Ceased
- 2008-08-28 CA CA2694401A patent/CA2694401C/en not_active Expired - Fee Related
- 2008-08-28 CN CN200880104785XA patent/CN101815713B/zh not_active Expired - Fee Related
- 2008-08-28 KR KR1020107005314A patent/KR20100055456A/ko not_active Abandoned
- 2008-08-28 MY MYPI20100422 patent/MY150507A/en unknown
- 2008-08-28 AR ARP080103739A patent/AR068121A1/es unknown
- 2008-08-28 JP JP2009530168A patent/JP5433418B2/ja not_active Expired - Fee Related
- 2008-08-28 PE PE2008001455A patent/PE20090674A1/es not_active Application Discontinuation
- 2008-08-28 EP EP08828870.9A patent/EP2181992B8/en active Active
- 2008-08-28 MX MX2010002098A patent/MX2010002098A/es active IP Right Grant
- 2008-08-28 ES ES12191398.2T patent/ES2529648T3/es active Active
- 2008-08-28 CL CL2008002542A patent/CL2008002542A1/es unknown
- 2008-08-28 NZ NZ583515A patent/NZ583515A/en not_active IP Right Cessation
- 2008-08-28 AU AU2008292390A patent/AU2008292390B2/en not_active Ceased
-
2010
- 2010-01-21 ZA ZA2010/00474A patent/ZA201000474B/en unknown
- 2010-02-08 IL IL203778A patent/IL203778A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20090674A1 (es) | 2009-06-19 |
| MY150507A (en) | 2014-01-30 |
| TW200916469A (en) | 2009-04-16 |
| CA2694401A1 (en) | 2009-03-05 |
| EP2559693B1 (en) | 2014-11-26 |
| CA2694401C (en) | 2012-12-04 |
| WO2009028588A1 (ja) | 2009-03-05 |
| EP2181992B1 (en) | 2013-05-01 |
| AU2008292390B2 (en) | 2013-04-04 |
| KR20100055456A (ko) | 2010-05-26 |
| JPWO2009028588A1 (ja) | 2010-12-02 |
| EP2559693A1 (en) | 2013-02-20 |
| EP2181992A4 (en) | 2011-09-14 |
| EP2181992B8 (en) | 2013-06-26 |
| ZA201000474B (en) | 2011-05-25 |
| US9453000B2 (en) | 2016-09-27 |
| MX2010002098A (es) | 2010-03-30 |
| CL2008002542A1 (es) | 2009-01-02 |
| AR068121A1 (es) | 2009-11-04 |
| ES2529648T3 (es) | 2015-02-24 |
| CN101815713B (zh) | 2013-09-11 |
| US20110009619A1 (en) | 2011-01-13 |
| AU2008292390A1 (en) | 2009-03-05 |
| IL203778A (en) | 2013-11-28 |
| CN101815713A (zh) | 2010-08-25 |
| EP2181992A1 (en) | 2010-05-05 |
| JP5433418B2 (ja) | 2014-03-05 |
| NZ583515A (en) | 2011-05-27 |
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