BRPI0815773A2 - composto, e, medicamento. - Google Patents
composto, e, medicamento.Info
- Publication number
- BRPI0815773A2 BRPI0815773A2 BRPI0815773A BRPI0815773A BRPI0815773A2 BR PI0815773 A2 BRPI0815773 A2 BR PI0815773A2 BR PI0815773 A BRPI0815773 A BR PI0815773A BR PI0815773 A BRPI0815773 A BR PI0815773A BR PI0815773 A2 BRPI0815773 A2 BR PI0815773A2
- Authority
- BR
- Brazil
- Prior art keywords
- medicine
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007225045 | 2007-08-31 | ||
| JP2008020009 | 2008-01-31 | ||
| JP2008123057 | 2008-05-09 | ||
| PCT/JP2008/065365 WO2009028588A1 (ja) | 2007-08-31 | 2008-08-28 | 多環式化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0815773A2 true BRPI0815773A2 (pt) | 2019-09-24 |
Family
ID=40387302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0815773A BRPI0815773A2 (pt) | 2007-08-31 | 2008-08-28 | composto, e, medicamento. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US9453000B2 (pt) |
| EP (2) | EP2559693B1 (pt) |
| JP (1) | JP5433418B2 (pt) |
| KR (1) | KR20100055456A (pt) |
| CN (1) | CN101815713B (pt) |
| AR (1) | AR068121A1 (pt) |
| AU (1) | AU2008292390B2 (pt) |
| BR (1) | BRPI0815773A2 (pt) |
| CA (1) | CA2694401C (pt) |
| CL (1) | CL2008002542A1 (pt) |
| ES (1) | ES2529648T3 (pt) |
| IL (1) | IL203778A (pt) |
| MX (1) | MX2010002098A (pt) |
| MY (1) | MY150507A (pt) |
| NZ (1) | NZ583515A (pt) |
| PE (1) | PE20090674A1 (pt) |
| TW (1) | TW200916469A (pt) |
| WO (1) | WO2009028588A1 (pt) |
| ZA (1) | ZA201000474B (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| ES2529648T3 (es) | 2007-08-31 | 2015-02-24 | Eisai R&D Management Co., Ltd. | Compuesto policíclico |
| US8129530B2 (en) * | 2007-08-31 | 2012-03-06 | H. Lundbeck A/S | Catecholamine derivatives and prodrugs thereof |
| US7935815B2 (en) * | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
| MX2011002002A (es) * | 2008-08-27 | 2011-03-29 | Eisai R&D Man Co Ltd | Proceso para preparar ciertos compuestos de cinnamida. |
| KR20180011888A (ko) | 2008-11-19 | 2018-02-02 | 포럼 파마슈티칼즈 인크. | (r)-7-클로로-n-(퀴누클리딘-3-일)벤조[b]티오펜-2-카르복사미드 및 그 약학적으로 허용가능한 염을 이용한 인지 장애의 치료 |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| BRPI1007883A2 (pt) * | 2009-02-26 | 2016-02-23 | Eisai R&D Man Co Ltd | sal, e, cristal. |
| JP2012121809A (ja) * | 2009-02-26 | 2012-06-28 | Eisai R & D Management Co Ltd | 多環式化合物の製造法およびその中間体 |
| WO2010098487A1 (en) | 2009-02-26 | 2010-09-02 | Eisai R&D Management Co., Ltd. | Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors |
| JP2012051805A (ja) * | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | テトラヒドロトリアゾロピリジン誘導体の製造方法 |
| US20100298348A1 (en) * | 2009-05-11 | 2010-11-25 | Kim Nicholas Green | Method of Decreasing Ubiquitylated Protein Levels |
| PE20120324A1 (es) * | 2009-05-11 | 2012-04-17 | Envivo Pharmaceuticals Inc | Combinacion que comprende (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y donezepilo como moduladora de trastornos cognitivos |
| CA2769392A1 (en) * | 2009-07-31 | 2011-02-03 | Sandoz Ag | Method for the preparation of w-amino-alkaneamides and w-amino-alkanethioamides as well as intermediates of this method |
| BR112012017310A2 (pt) | 2010-01-15 | 2016-04-19 | Janssen Pharmaceuticals Inc | derivados de triazol substituídos como moduladores de gama secretase |
| AR081402A1 (es) | 2010-05-17 | 2012-08-29 | Envivo Pharmaceuticals Inc | Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il) benzo(b)tiofeno-2-carboxamida monohidrato |
| EP2691393B1 (en) | 2011-03-31 | 2016-09-14 | Pfizer Inc | Novel bicyclic pyridinones |
| CA2872005A1 (en) | 2012-05-08 | 2013-11-14 | Forum Pharmaceuticals, Inc. | Methods of maintaining, treating or improving cognitive function |
| US9181245B2 (en) | 2012-05-16 | 2015-11-10 | Janssen Pharmaceuticals, Inc. | Substituted pyrido[1,2-a]pyrazines and substituted pyrido[1,2-a][1,4]diazepines for the treatment of (inter alia) Alzheimer's disease |
| UA110688C2 (uk) | 2012-09-21 | 2016-01-25 | Пфайзер Інк. | Біциклічні піридинони |
| CA2889249C (en) | 2012-12-20 | 2021-02-16 | Francois Paul Bischoff | Tricyclic 3,4-dihydro-2h-pyrido[1,2-a]pyrazine-1,6-dione derivatives as gamma secretase modulators |
| CA2891755C (en) | 2013-01-17 | 2021-10-26 | Janssen Pharmaceutica Nv | Substituted pyrido-piperazinone derivatives as gamma secretase modulators |
| US10372396B2 (en) * | 2013-02-21 | 2019-08-06 | Lenovo ( Singapore) Pte. Ltd. | Discovery and connection to wireless displays |
| US10562897B2 (en) | 2014-01-16 | 2020-02-18 | Janssen Pharmaceutica Nv | Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators |
| MX368391B (es) | 2015-02-03 | 2019-09-30 | Pfizer | Ciclopropabenzofuranil-piridopirazindionas novedosas. |
| US11020403B2 (en) * | 2017-06-02 | 2021-06-01 | Xeris Pharmaceuticals, Inc. | Precipitation resistant small molecule drug formulations |
| WO2019149965A1 (en) * | 2018-02-05 | 2019-08-08 | Universite De Strasbourg | Compounds and compositions for the treatment of pain |
| CN113573708A (zh) * | 2019-02-07 | 2021-10-29 | 阿尔萨泰克公司 | 艾莫西平多价衍生物 |
| JP2025541281A (ja) * | 2022-12-15 | 2025-12-18 | シトリクス・セラピューティクス・リミテッド | 炎症性疾患若しくは望ましくない免疫応答に関連する疾患の治療又は予防に使用するための置換ピリジン |
| CN118459425B (zh) * | 2024-04-29 | 2025-11-14 | 南通华祥医药科技有限公司 | 一种吡咯烷-1-胺-二盐酸盐的制备方法 |
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| EP2155740B1 (en) | 2007-05-11 | 2011-01-26 | F. Hoffmann-La Roche AG | Hetarylanilines as modulators for amyloid beta |
| EP2166854A4 (en) | 2007-06-13 | 2012-05-16 | Merck Sharp & Dohme | TRIAZONE DERIVATIVES FOR THE TREATMENT OF MORBUS ALZHEIMER AND RELATED SUFFERINGS |
| MX2010001506A (es) | 2007-08-06 | 2010-03-10 | Schering Corp | Moduladores de gamma secretasa. |
| US7935815B2 (en) * | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
| ES2529648T3 (es) | 2007-08-31 | 2015-02-24 | Eisai R&D Management Co., Ltd. | Compuesto policíclico |
| US8450343B2 (en) | 2007-12-06 | 2013-05-28 | Xianhai Huang | Gamma secretase modulators |
| WO2009126311A1 (en) * | 2008-04-11 | 2009-10-15 | The University Of Texas, M.D. Anderson Cancer Center | Radiosensitization of tumors with indazolpyrrolotriazines for radiotherapy |
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| JP2012051806A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
| ES2439773T3 (es) | 2009-02-26 | 2014-01-24 | Glaxo Group Limited | Derivados de pirazol usados como antagonistas del receptor CCR4 |
| BRPI1007883A2 (pt) | 2009-02-26 | 2016-02-23 | Eisai R&D Man Co Ltd | sal, e, cristal. |
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| US8381014B2 (en) * | 2010-05-06 | 2013-02-19 | International Business Machines Corporation | Node controller first failure error management for a distributed system |
-
2008
- 2008-08-28 ES ES12191398.2T patent/ES2529648T3/es active Active
- 2008-08-28 NZ NZ583515A patent/NZ583515A/en not_active IP Right Cessation
- 2008-08-28 MX MX2010002098A patent/MX2010002098A/es active IP Right Grant
- 2008-08-28 US US12/671,873 patent/US9453000B2/en not_active Expired - Fee Related
- 2008-08-28 AR ARP080103739A patent/AR068121A1/es unknown
- 2008-08-28 WO PCT/JP2008/065365 patent/WO2009028588A1/ja not_active Ceased
- 2008-08-28 CL CL2008002542A patent/CL2008002542A1/es unknown
- 2008-08-28 KR KR1020107005314A patent/KR20100055456A/ko not_active Abandoned
- 2008-08-28 CN CN200880104785XA patent/CN101815713B/zh not_active Expired - Fee Related
- 2008-08-28 JP JP2009530168A patent/JP5433418B2/ja not_active Expired - Fee Related
- 2008-08-28 EP EP12191398.2A patent/EP2559693B1/en active Active
- 2008-08-28 AU AU2008292390A patent/AU2008292390B2/en not_active Ceased
- 2008-08-28 PE PE2008001455A patent/PE20090674A1/es not_active Application Discontinuation
- 2008-08-28 CA CA2694401A patent/CA2694401C/en not_active Expired - Fee Related
- 2008-08-28 EP EP08828870.9A patent/EP2181992B8/en active Active
- 2008-08-28 MY MYPI20100422 patent/MY150507A/en unknown
- 2008-08-28 BR BRPI0815773A patent/BRPI0815773A2/pt not_active IP Right Cessation
- 2008-08-28 TW TW097132893A patent/TW200916469A/zh unknown
-
2010
- 2010-01-21 ZA ZA2010/00474A patent/ZA201000474B/en unknown
- 2010-02-08 IL IL203778A patent/IL203778A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2559693A1 (en) | 2013-02-20 |
| JP5433418B2 (ja) | 2014-03-05 |
| WO2009028588A1 (ja) | 2009-03-05 |
| JPWO2009028588A1 (ja) | 2010-12-02 |
| ES2529648T3 (es) | 2015-02-24 |
| NZ583515A (en) | 2011-05-27 |
| AU2008292390B2 (en) | 2013-04-04 |
| CL2008002542A1 (es) | 2009-01-02 |
| EP2559693B1 (en) | 2014-11-26 |
| EP2181992B1 (en) | 2013-05-01 |
| US20110009619A1 (en) | 2011-01-13 |
| IL203778A (en) | 2013-11-28 |
| EP2181992A1 (en) | 2010-05-05 |
| ZA201000474B (en) | 2011-05-25 |
| AR068121A1 (es) | 2009-11-04 |
| CA2694401A1 (en) | 2009-03-05 |
| CN101815713A (zh) | 2010-08-25 |
| PE20090674A1 (es) | 2009-06-19 |
| MY150507A (en) | 2014-01-30 |
| KR20100055456A (ko) | 2010-05-26 |
| US9453000B2 (en) | 2016-09-27 |
| CN101815713B (zh) | 2013-09-11 |
| EP2181992A4 (en) | 2011-09-14 |
| AU2008292390A1 (en) | 2009-03-05 |
| MX2010002098A (es) | 2010-03-30 |
| TW200916469A (en) | 2009-04-16 |
| CA2694401C (en) | 2012-12-04 |
| EP2181992B8 (en) | 2013-06-26 |
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