BRPI1013833A2 - resistência a múltiplos vírus em plantas - Google Patents

resistência a múltiplos vírus em plantas

Info

Publication number
BRPI1013833A2
BRPI1013833A2 BRPI1013833-1A BRPI1013833A BRPI1013833A2 BR PI1013833 A2 BRPI1013833 A2 BR PI1013833A2 BR PI1013833 A BRPI1013833 A BR PI1013833A BR PI1013833 A2 BRPI1013833 A2 BR PI1013833A2
Authority
BR
Brazil
Prior art keywords
plant
resistance
viruses
relates
present
Prior art date
Application number
BRPI1013833-1A
Other languages
English (en)
Inventor
Huang Shihshieh
Flasinski Stanislaw
Frizzi Alessandra
Gabor Brad
Hagen Charles
Kao John
Salati Raquel
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of BRPI1013833A2 publication Critical patent/BRPI1013833A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

resistência a múltiplos vírus em plantas a presente invenção refere-se a genes-alvo, construtos e métodos para o controle genético de doenças de plantas 5 causadas por múltiplos vírus de plantas. a presente invenção refere-se à obtenção de um efeito protetor da planta mediante a identificação de sequências codificadas alvo e uso de tecnologias de dna recombinante para repressão ou inibição pós-transcricional da expressão de sequências codificadoras alvo de vírus parasitas de plantas. também se podem utilizar abordagens baseadas na expressão de proteínas para aumentar a resistência do fenótipo. assim, a transcrição de um único evento transgênico compreendendo um ou mais cassetes de expressão em plantas pode permitir uma resistência de amplo espectro de uma planta a múltiplas cepas e espécies virais dentre os geminivírus, tospovírus e potexvírus.
BRPI1013833-1A 2009-04-20 2010-04-20 resistência a múltiplos vírus em plantas BRPI1013833A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17102109P 2009-04-20 2009-04-20
US61/171,021 2009-04-20
PCT/US2010/031757 WO2010123904A1 (en) 2009-04-20 2010-04-20 Multiple virus resistance in plants

Publications (1)

Publication Number Publication Date
BRPI1013833A2 true BRPI1013833A2 (pt) 2019-04-09

Family

ID=42272567

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1013833-1A BRPI1013833A2 (pt) 2009-04-20 2010-04-20 resistência a múltiplos vírus em plantas

Country Status (14)

Country Link
US (4) US8455716B2 (pt)
EP (2) EP3260545B1 (pt)
JP (1) JP2012523850A (pt)
KR (1) KR20140014374A (pt)
CN (1) CN102428187A (pt)
AU (1) AU2010239381B2 (pt)
BR (1) BRPI1013833A2 (pt)
CA (1) CA2759291C (pt)
ES (1) ES2651909T3 (pt)
IL (1) IL215853A (pt)
MA (1) MA33281B1 (pt)
MX (1) MX2011011076A (pt)
WO (1) WO2010123904A1 (pt)
ZA (1) ZA201107675B (pt)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2759291C (en) 2009-04-20 2020-09-15 Monsanto Technology Llc Multiple virus resistance in transgenic tomato plants
KR102095850B1 (ko) * 2011-11-02 2020-04-02 리즈크 즈완 자드틸트 엔 자드한델 비.브이. 페피노 모자이크 바이러스 저항성 토마토 식물
US9339655B2 (en) 2012-06-30 2016-05-17 Boston Scientific Neuromodulation Corporation System and method for compounding low-frequency sources for high-frequency neuromodulation
US9002459B2 (en) 2012-09-19 2015-04-07 Boston Scientific Neuromodulation Corporation Method for selectively modulating neural elements in the dorsal horn
WO2014062775A2 (en) * 2012-10-16 2014-04-24 Monsanto Technology Llc Methods and compositions for controlling plant viral infection
AU2014218716B2 (en) 2013-02-22 2017-10-19 Boston Scientific Neuromodulation Corporation Neurostimulation system having increased flexibility for creating complex pulse trains
US9174053B2 (en) 2013-03-08 2015-11-03 Boston Scientific Neuromodulation Corporation Neuromodulation using modulated pulse train
EP2968933B1 (en) 2013-03-15 2019-06-12 Boston Scientific Neuromodulation Corporation Systems for delivering sub-threshold therapy to a patient
US9180297B2 (en) 2013-05-16 2015-11-10 Boston Scientific Neuromodulation Corporation System and method for spinal cord modulation to treat motor disorder without paresthesia
US9950173B2 (en) 2013-06-06 2018-04-24 Boston Scientific Neuromodulation Corporation System and method for delivering sub-threshold and super-threshold therapy to a patient
US10029102B2 (en) 2013-06-06 2018-07-24 Boston Scientific Neuromodulation Corporation System and method for delivering modulated sub-threshold therapy to a patient
WO2014210373A1 (en) 2013-06-28 2014-12-31 Boston Scientific Neuromodulation Corporation Electrode selection for sub-threshold modulation therapy
JP6181307B2 (ja) 2013-07-26 2017-08-16 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 知覚なしに変調治療を与えるシステム
WO2015066033A1 (en) 2013-10-30 2015-05-07 Boston Scientific Neuromodulation Corporation Fractional control to avoid dorsal root stimulation
WO2015066295A1 (en) 2013-10-31 2015-05-07 Boston Scientific Neuromodulation Corporation System to incorporate lead information from image
JP6339194B2 (ja) 2013-11-01 2018-06-06 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 正中線で閾値以下治療を送出するためのシステム
CN103667322B (zh) * 2013-11-21 2015-11-11 上海市农业科学院 一种抗番茄黄化曲叶病毒的多基因嵌合体avctc及其制备方法和应用
US10010715B2 (en) 2013-12-04 2018-07-03 Boston Scientific Neuromodulation Corporation Systems and methods for delivering therapy to the dorsal horn of a patient
WO2015089411A2 (en) 2013-12-12 2015-06-18 Boston Scientific Neuromodulation Corporation Systems and methods for programming a neuromodulation system
WO2015119773A1 (en) 2014-02-05 2015-08-13 Jordi Parramon System and method for delivering modulated sub-threshold therapy to a patient
US9381360B2 (en) 2014-02-05 2016-07-05 Boston Scientific Neuromodulation Corporation System and method for delivering modulated sub-threshold therapy to a patient
CN109908481B (zh) 2014-07-03 2023-06-20 波士顿科学神经调制公司 具有灵活模式和波形的神经刺激系统
CA2954855C (en) 2014-07-24 2020-08-18 Boston Scientific Neuromodulation Corporation Enhanced dorsal horn stimulation using multiple electrical fields
CN106687173A (zh) 2014-09-15 2017-05-17 波士顿科学神经调制公司 用于对神经刺激脉冲模式进行编程的图形用户界面
CN106687174B (zh) 2014-09-23 2019-12-03 波士顿科学神经调制公司 专用于针对目标组织的调制场的目标函数的神经调制
JP6564851B2 (ja) 2014-09-23 2019-08-21 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 短パルス幅刺激
JP6498754B2 (ja) 2014-09-23 2019-04-10 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 患者入力に応答する知覚以下変調
WO2016048756A1 (en) 2014-09-23 2016-03-31 Boston Scientific Neuromodulation Corporation System for calibrating dorsal horn stimulation
US9764141B2 (en) 2014-09-23 2017-09-19 Boston Scientific Neuromodulation Corporation Neuromodulation with burst stimulation
AU2015321575B2 (en) 2014-09-23 2018-05-10 Boston Scientific Neuromodulation Corporation Perception calibration of neural tissue using field troll
AU2015321576B2 (en) 2014-09-23 2018-11-08 Boston Scientific Neuromodulation Corporation Systems and methods for receiving user-provided selection of electrode lists
WO2016064347A1 (en) 2014-10-22 2016-04-28 Temasek Life Sciences Laboratory Limited Terpene synthases from ylang ylang (cananga odorata var. fruticosa)
JP6452836B2 (ja) 2014-11-04 2019-01-16 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 複合神経刺激パターンをプログラムする方法及び装置
US9849287B2 (en) 2015-02-09 2017-12-26 Boston Scientific Neuromodulation Corporation System and method for determining the neurological position of epidural leads
EP3302690B1 (en) 2015-05-28 2019-09-25 Boston Scientific Neuromodulation Corporation Neuromodulation system using stochastically-modulated stimulation parameters
EP3328481B1 (en) 2015-07-30 2019-05-15 Boston Scientific Neuromodulation Corporation User interface for custom patterned electrical stimulation
US10456586B2 (en) 2015-10-15 2019-10-29 Boston Scientific Neuromodulation Corporation User interface for neurostimulation waveform composition
CN106609277B (zh) * 2015-10-22 2021-02-12 中国种子集团有限公司 重组核酸片段RecCR020142及其检测方法
BR112018011174A2 (pt) * 2015-11-30 2018-11-21 Du Pont polinucleotídeo recombinante, construto de dna, célula heteróloga, planta transgênica ou célula de planta, semente da planta transgênica, método para expressar um polinucleotídeo em uma planta e método para aprimorar a transcrição de um polinucleotídeo em uma célula hospedeira
US11254943B2 (en) 2016-02-05 2022-02-22 Temasek Life Sciences Laboratory Limited Intron-containing promoters and uses thereof
EP3238533A1 (en) * 2016-04-28 2017-11-01 Semillas Fito, S. A. Begomovirus-resistant melon plants
CN109475098B (zh) * 2016-07-12 2022-05-27 纽海姆有限公司 ToLCNDV抗性甜瓜植物
US11591611B2 (en) 2016-07-12 2023-02-28 Nunhems B.V. TolCNDV resistant melon plants
IL264127B2 (en) 2016-07-12 2024-02-01 Nunhems Bv TOLCNDV resistant melon plants
US10780274B2 (en) 2016-08-22 2020-09-22 Boston Scientific Neuromodulation Corporation Systems and methods for delivering spinal cord stimulation therapy
CA3045784A1 (en) 2016-10-11 2018-05-17 Dow Agrosciences Llc Modulation of transgene expression in plants
CN107918017A (zh) * 2016-12-26 2018-04-17 云南农业大学 一种快速检测辣椒褪绿病毒的血清学方法
US12408674B2 (en) 2018-03-09 2025-09-09 Monsanto Technology Llc Methods and compositions for controlling plant viral infection
CN109234221B (zh) * 2018-11-19 2021-12-21 东北农业大学 一种马铃薯x病毒弱毒疫苗及其制备方法与应用
KR102944320B1 (ko) 2019-03-01 2026-03-25 신젠타 크롭 프로텍션 아게 네이티브 miRNA의 게놈 편집을 통한 표적 유전자 발현의 억제
CN110999694A (zh) * 2020-02-27 2020-04-14 天津市植物保护研究所 绿色防控番茄苗期烟粉虱及tylcv的方法
WO2021234101A1 (en) 2020-05-20 2021-11-25 KWS SAAT SE & Co. KGaA Multiple virus resistance
CN111778274A (zh) * 2020-06-09 2020-10-16 新疆生产建设兵团第六师农业科学研究所 一种通过基因编辑提高番茄耐贮藏性的方法
CN112625141A (zh) * 2020-12-28 2021-04-09 昆明海关技术中心 一种番茄斑萎属病毒的蛋白标准物质及其应用
EP4328311A4 (en) * 2021-04-21 2025-04-30 Zhejiang University NEGATIVE-STRAND RNA VIRUS VECTOR AND PLANT GENOME EDITING WITHOUT TRANSFORMATION
CN112980847B (zh) * 2021-04-21 2023-05-02 中国热带农业科学院橡胶研究所 一种橡胶树泛素基因启动子proHbUBI3及其克隆与应用
ES2931248A1 (es) * 2021-06-18 2022-12-27 Abiopep S L Plantas resistentes a la infección por el virus del mosaico del pepino dulce
WO2023069905A1 (en) * 2021-10-19 2023-04-27 University Of Florida Research Foundation, Inc. Insect toxin delivery mediated by a begomovirus coat protein
WO2023077118A1 (en) 2021-11-01 2023-05-04 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
CN114015718B (zh) * 2021-11-24 2023-07-18 中国农业科学院植物保护研究所 大豆黄曲叶病毒侵染性克隆载体及其构建方法和应用
KR20240135651A (ko) 2022-01-20 2024-09-11 플래그쉽 파이어니어링 이노베이션스 Vii, 엘엘씨 유기체를 변형하기 위한 폴리뉴클레오티드
AU2023241138A1 (en) * 2022-03-21 2024-09-26 Donald Danforth Plant Science Center Geminivirus resistant plants
CN116426567B (zh) * 2023-03-29 2023-11-03 潍坊科技学院 一种n基因及其蛋白在抗番茄黄化曲叶病毒中的应用
AR132589A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de solemoviridae artificiales
EP4705478A1 (en) 2023-05-03 2026-03-11 Flagship Pioneering Innovations VII, LLC Artificial martellivirales satellite rnas
EP4705476A1 (en) 2023-05-03 2026-03-11 Flagship Pioneering Innovations VII, LLC Artificial amalgavirus satellite rnas
AR132591A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de secoviridae artificiales
CN121712898A (zh) 2023-05-03 2026-03-20 旗舰创业创新第七有限责任公司 用于植物的内源核糖核酸病毒卫星rna扩增系统
EP4705474A2 (en) 2023-05-03 2026-03-11 Flagship Pioneering Innovations VII, LLC Artificial tymovirales satellite rnas
EP4705470A1 (en) 2023-05-03 2026-03-11 Flagship Pioneering Innovations VII, LLC Artificial tombusviridae satellite rnas
CN121712897A (zh) 2023-05-03 2026-03-20 旗舰创业创新第七有限责任公司 用于植物的分体病毒卫星rna扩增系统
AR132592A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de ghabrivirales artificiales
CN119570986A (zh) * 2025-02-08 2025-03-07 浙江大学 同时检测茄科植物上两种双生病毒的组合引物及检测方法

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4693977A (en) 1982-08-23 1987-09-15 Queen's University At Kingston Enzyme immobilization for producing cephalosporin antibiotics
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
NZ207765A (en) 1983-04-15 1987-03-06 Lubrizol Genetics Inc Plant expression of transferred dna(t-dna)from plasmids associated with agrobacterium sp
US5190931A (en) 1983-10-20 1993-03-02 The Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US5208149A (en) 1983-10-20 1993-05-04 The Research Foundation Of State University Of New York Nucleic acid constructs containing stable stem and loop structures
US5272065A (en) 1983-10-20 1993-12-21 Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US4886937A (en) 1985-05-20 1989-12-12 North Carolina State University Method for transforming pine
CA1293460C (en) 1985-10-07 1991-12-24 Brian Lee Sauer Site-specific recombination of dna in yeast
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US5453566A (en) 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US5015580A (en) 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
ATE87032T1 (de) 1986-12-05 1993-04-15 Ciba Geigy Ag Verbessertes verfahren zur transformation von pflanzlichen protoplasten.
US5416011A (en) 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
US5110732A (en) 1989-03-14 1992-05-05 The Rockefeller University Selective gene expression in plants
US5231020A (en) 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5302523A (en) 1989-06-21 1994-04-12 Zeneca Limited Transformation of plant cells
US5501967A (en) 1989-07-26 1996-03-26 Mogen International, N.V./Rijksuniversiteit Te Leiden Process for the site-directed integration of DNA into the genome of plants
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
WO1991010725A1 (en) 1990-01-22 1991-07-25 Dekalb Plant Genetics Fertile transgenic corn plants
US5484956A (en) 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
US5837848A (en) 1990-03-16 1998-11-17 Zeneca Limited Root-specific promoter
US6403865B1 (en) 1990-08-24 2002-06-11 Syngenta Investment Corp. Method of producing transgenic maize using direct transformation of commercially important genotypes
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
US5384253A (en) 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
US5459252A (en) 1991-01-31 1995-10-17 North Carolina State University Root specific gene promoter
US5262316A (en) 1991-11-22 1993-11-16 Dna Plant Technology Corporation Genetically transformed pepper plants and methods for their production
PL172710B1 (pl) 1992-07-02 1997-11-28 Hybridon Inc Samostabilizujacy sie oligonukleotyd PL PL
ATE398679T1 (de) 1992-07-07 2008-07-15 Japan Tobacco Inc Verfahren zur transformation einer monokotyledon pflanze
JP2952041B2 (ja) 1992-07-27 1999-09-20 パイオニア ハイ−ブレッド インターナショナル，インコーポレイテッド 培養ダイズ細胞のａｇｒｏｂａｃｔｅｒｉｕｍ媒介形質転換の改良法
US5527695A (en) 1993-01-29 1996-06-18 Purdue Research Foundation Controlled modification of eukaryotic genomes
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
US5693512A (en) 1996-03-01 1997-12-02 The Ohio State Research Foundation Method for transforming plant tissue by sonication
US5850019A (en) 1996-08-06 1998-12-15 University Of Kentucky Research Foundation Promoter (FLt) for the full-length transcript of peanut chlorotic streak caulimovirus (PCLSV) and expression of chimeric genes in plants
DE19631919C2 (de) 1996-08-07 1998-07-16 Deutsches Krebsforsch Anti-Sinn-RNA mit Sekundärstruktur
DE19644478A1 (de) 1996-10-25 1998-04-30 Basf Ag Blattspezifische Expression von Genen in transgenen Pflanzen
US5981840A (en) 1997-01-24 1999-11-09 Pioneer Hi-Bred International, Inc. Methods for agrobacterium-mediated transformation
CA2281002A1 (en) 1997-02-19 1998-08-27 Cornell Research Foundation, Inc. Dna construct to confer multiple traits on plants
US20020059660A1 (en) 1997-10-06 2002-05-16 Tricoli David M. Transgenic plants expressing DNA constructs containing a plurality of genes to impart virus resistance
US6852907B1 (en) 1998-03-03 2005-02-08 The Scripps Research Institute Resistance in plants to infection by ssDNA virus using inoviridae virus ssDNA-binding protein, compositions and methods of use
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
CN1202246C (zh) 1998-04-08 2005-05-18 联邦科学和工业研究组织 获得修饰表型的方法和措施
US6818612B2 (en) 1998-11-24 2004-11-16 Kristina Broliden Use of parvovirus capsid particles in the inhibition of cell proliferation and migration
WO2000042207A2 (en) 1999-01-14 2000-07-20 Monsanto Technology Llc Soybean transformation method
US7109393B2 (en) 2000-08-15 2006-09-19 Mendel Biotechnology, Inc. Methods of gene silencing using inverted repeat sequences
US20020048814A1 (en) 2000-08-15 2002-04-25 Dna Plant Technology Corporation Methods of gene silencing using poly-dT sequences
AUPR155800A0 (en) 2000-11-17 2000-12-14 Agriculture Victoria Services Pty Ltd Method of enhancing virus-resistance in plants and producing virus-immune plants
AR039717A1 (es) 2002-06-21 2005-03-09 Monsanto Technology Llc Construcciones de arn de intrones cadena doble y usos de las mismas
US20050144669A1 (en) 2003-07-01 2005-06-30 Whitehead Institute For Biomedical Research MicroRNAs in plants
IL157538A0 (en) 2003-08-21 2004-03-28 Bar Ilan Res & Dev Company Ltd Plant resistant to cytoplasm-feeding parasites
US20050120415A1 (en) 2003-10-09 2005-06-02 E.I. Du Pont De Nemours And Company Gene silencing
US8314290B2 (en) 2004-12-21 2012-11-20 Monsanto Technology Llc Temporal regulation of gene expression by MicroRNAs
US20060200878A1 (en) 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
US8030473B2 (en) 2005-01-07 2011-10-04 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method to trigger RNA interference
CN105385679B (zh) 2006-02-13 2020-05-26 孟山都技术有限公司 选择和稳定dsRNA构建体
WO2008027592A2 (en) 2006-08-31 2008-03-06 Monsanto Technology, Llc Phased small rnas
CA2759291C (en) 2009-04-20 2020-09-15 Monsanto Technology Llc Multiple virus resistance in transgenic tomato plants

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