BRPI1013872A2 - formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosa - Google Patents
formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosaInfo
- Publication number
- BRPI1013872A2 BRPI1013872A2 BRPI1013872A BRPI1013872A BRPI1013872A2 BR PI1013872 A2 BRPI1013872 A2 BR PI1013872A2 BR PI1013872 A BRPI1013872 A BR PI1013872A BR PI1013872 A BRPI1013872 A BR PI1013872A BR PI1013872 A2 BRPI1013872 A2 BR PI1013872A2
- Authority
- BR
- Brazil
- Prior art keywords
- calcium
- altering
- biophysical properties
- mucosal lining
- lactate formulations
- Prior art date
Links
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 title 1
- 239000001354 calcium citrate Substances 0.000 title 1
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 title 1
- 239000001527 calcium lactate Substances 0.000 title 1
- 229960002401 calcium lactate Drugs 0.000 title 1
- 235000011086 calcium lactate Nutrition 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 235000013337 tricalcium citrate Nutrition 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16377209P | 2009-03-26 | 2009-03-26 | |
| US26774709P | 2009-12-08 | 2009-12-08 | |
| PCT/US2010/028914 WO2010111650A2 (en) | 2009-03-26 | 2010-03-26 | Calcium citrate and calcium lactate formulations for alteration of biophysical properties of mucosal lining |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1013872A2 true BRPI1013872A2 (pt) | 2018-06-19 |
Family
ID=42635141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1013872A BRPI1013872A2 (pt) | 2009-03-26 | 2010-03-26 | formulações de citrato de cálcio e lactato de cálcio para alteração de propriedades biofísicas do revestimento da mucosa |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20120083531A1 (pt) |
| EP (1) | EP2410986A2 (pt) |
| JP (1) | JP2012522012A (pt) |
| KR (1) | KR20120015295A (pt) |
| CN (1) | CN102448439A (pt) |
| AU (1) | AU2010229730A1 (pt) |
| BR (1) | BRPI1013872A2 (pt) |
| CA (1) | CA2754684A1 (pt) |
| IL (1) | IL214921A0 (pt) |
| MX (1) | MX2011009956A (pt) |
| WO (1) | WO2010111650A2 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2011009959A (es) * | 2009-03-26 | 2012-01-27 | Pulmatrix Inc | Formulaciones farmaceuticas y metodos para el tratamiento de enfermedades del tracto respiratorio. |
| MX354829B (es) | 2009-03-26 | 2018-03-22 | Pulmatrix Operating Co Inc | Formulaciones de polvo seco y metodos para el tratamiento de enfermedades pulmonares. |
| GB0918450D0 (en) * | 2009-10-21 | 2009-12-09 | Innovata Ltd | Composition |
| CA2809666C (en) * | 2010-08-30 | 2020-09-22 | Michael M. Lipp | Dry powder formulations and methods for treating pulmonary diseases |
| EP2464346A1 (en) | 2010-08-30 | 2012-06-20 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
| RU2640921C2 (ru) | 2010-09-29 | 2018-01-12 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
| AU2011314007B2 (en) | 2010-09-29 | 2017-01-19 | Pulmatrix, Inc. | Cationic dry powders |
| WO2013052844A1 (en) | 2011-10-07 | 2013-04-11 | Pulmatrix, Inc. | Methods for treating and diagnosing respiratory tract infections |
| PT106094A (pt) * | 2012-01-13 | 2013-07-15 | Hovione Farmaciencia S A | Administração por inalação de formulações com dose elevada |
| JP2015509788A (ja) | 2012-02-29 | 2015-04-02 | パルマトリックス，インコーポレイテッド | 吸入に適した乾燥粉末 |
| CA2907566C (en) | 2013-04-01 | 2023-08-22 | Pulmatrix, Inc. | Tiotropium dry powders |
| US20160235667A1 (en) * | 2013-10-02 | 2016-08-18 | Vectura Limited | Method and apparatus for making compositions for pulmonary administration |
| RU2628800C2 (ru) * | 2014-03-12 | 2017-08-22 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами |
| AU2015338717B2 (en) | 2014-10-31 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Powder formulation |
| KR101683635B1 (ko) * | 2014-12-29 | 2016-12-09 | 가천대학교 산학협력단 | 락테이트 금속염을 포함하는 암 치료용 약학 조성물 |
| WO2016109541A1 (en) * | 2014-12-29 | 2016-07-07 | Academia Sinica | Method for treating influenza a virus infection |
| JP6940416B2 (ja) * | 2015-05-01 | 2021-09-29 | ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | 多剤脆性マトリックス組成物 |
| US10046007B2 (en) | 2015-06-24 | 2018-08-14 | Prescient Pharma, Llc | Compositions and methods for treatment of short telomere disorders |
| KR20180062063A (ko) | 2016-11-30 | 2018-06-08 | (주) 메티메디제약 | 서방형 항암용 약학 조성물 |
| CN107648207A (zh) * | 2017-10-11 | 2018-02-02 | 北京北朋科技有限公司 | 雾化吸入用柠檬酸盐糖醇溶液 |
| CN111587110A (zh) | 2018-01-12 | 2020-08-25 | 麦提麦迪制药有限公司 | 治疗慢性炎症性疾病的方法 |
| CN110527628B (zh) * | 2019-07-30 | 2022-05-10 | 南京农业大学 | 一种啶虫脒降解菌的保护剂及其制备方法和应用 |
| IT202000005026A1 (it) * | 2020-03-09 | 2021-09-09 | Sofar Spa | Lattoferrina per uso inalatorio ad azione antivirale |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3414539B2 (ja) * | 1994-05-11 | 2003-06-09 | 有限会社ドット | 経鼻吸収用組成物 |
| US6586006B2 (en) * | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
| US5612053A (en) * | 1995-04-07 | 1997-03-18 | Edward Mendell Co., Inc. | Controlled release insufflation carrier for medicaments |
| IL161446A0 (en) * | 2001-11-26 | 2004-09-27 | Daiichi Suntory Pharma Co Ltd | Medicinal compositions for nasal absorption |
| GB0207906D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and mometasone aerosol formulations |
| NZ543201A (en) * | 2003-05-01 | 2007-05-31 | Innogene Kalbiotech Pte Ltd | Lactate containing pharmaceutical composition and uses thereof |
| US20050207983A1 (en) * | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
| EP1796653A2 (en) * | 2004-07-26 | 2007-06-20 | Actelion Pharmaceuticals Ltd. | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
| EP1906922A2 (en) * | 2005-05-18 | 2008-04-09 | Pulmatrix, Inc. | Formulations for alteration of biophysical properties of mucosal lining |
| MX2011009959A (es) * | 2009-03-26 | 2012-01-27 | Pulmatrix Inc | Formulaciones farmaceuticas y metodos para el tratamiento de enfermedades del tracto respiratorio. |
| CN102448438A (zh) * | 2009-03-26 | 2012-05-09 | 普马特里克斯公司 | 抗流行性感冒调配物及方法 |
-
2010
- 2010-03-26 AU AU2010229730A patent/AU2010229730A1/en not_active Abandoned
- 2010-03-26 MX MX2011009956A patent/MX2011009956A/es not_active Application Discontinuation
- 2010-03-26 WO PCT/US2010/028914 patent/WO2010111650A2/en not_active Ceased
- 2010-03-26 CA CA2754684A patent/CA2754684A1/en not_active Abandoned
- 2010-03-26 CN CN2010800232600A patent/CN102448439A/zh active Pending
- 2010-03-26 EP EP10722835A patent/EP2410986A2/en not_active Withdrawn
- 2010-03-26 US US13/259,666 patent/US20120083531A1/en not_active Abandoned
- 2010-03-26 JP JP2012502306A patent/JP2012522012A/ja active Pending
- 2010-03-26 BR BRPI1013872A patent/BRPI1013872A2/pt not_active IP Right Cessation
- 2010-03-26 KR KR1020117022476A patent/KR20120015295A/ko not_active Withdrawn
-
2011
- 2011-09-01 IL IL214921A patent/IL214921A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20120083531A1 (en) | 2012-04-05 |
| EP2410986A2 (en) | 2012-02-01 |
| WO2010111650A2 (en) | 2010-09-30 |
| JP2012522012A (ja) | 2012-09-20 |
| IL214921A0 (en) | 2011-11-30 |
| MX2011009956A (es) | 2012-01-27 |
| CN102448439A (zh) | 2012-05-09 |
| KR20120015295A (ko) | 2012-02-21 |
| CA2754684A1 (en) | 2010-09-30 |
| WO2010111650A3 (en) | 2010-11-18 |
| AU2010229730A1 (en) | 2011-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2477 DE 26-06-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |