BRPI1014247A2 - reversão da discinesia induzida pela l-dopa por ligantes de receptores nocotínicos neuronais. - Google Patents
reversão da discinesia induzida pela l-dopa por ligantes de receptores nocotínicos neuronais.Info
- Publication number
- BRPI1014247A2 BRPI1014247A2 BRPI1014247A BRPI1014247A BRPI1014247A2 BR PI1014247 A2 BRPI1014247 A2 BR PI1014247A2 BR PI1014247 A BRPI1014247 A BR PI1014247A BR PI1014247 A BRPI1014247 A BR PI1014247A BR PI1014247 A2 BRPI1014247 A2 BR PI1014247A2
- Authority
- BR
- Brazil
- Prior art keywords
- nocotinic
- dopa
- neuronal
- reversal
- receptor ligands
- Prior art date
Links
- 208000012661 Dyskinesia Diseases 0.000 title 1
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 230000001537 neural effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18789609P | 2009-06-17 | 2009-06-17 | |
| PCT/US2010/038605 WO2010147938A2 (en) | 2009-06-17 | 2010-06-15 | Reversal of l-dopa-induced dyskinesia by neuronal nicotinic receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1014247A2 true BRPI1014247A2 (pt) | 2016-04-12 |
Family
ID=43357005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1014247A BRPI1014247A2 (pt) | 2009-06-17 | 2010-06-15 | reversão da discinesia induzida pela l-dopa por ligantes de receptores nocotínicos neuronais. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20120157477A1 (pt) |
| EP (1) | EP2442810A4 (pt) |
| JP (1) | JP2012530707A (pt) |
| KR (1) | KR20120061047A (pt) |
| CN (1) | CN102802630A (pt) |
| AU (1) | AU2010260265A1 (pt) |
| BR (1) | BRPI1014247A2 (pt) |
| CA (1) | CA2763551A1 (pt) |
| IL (1) | IL216458A0 (pt) |
| MX (1) | MX2011013860A (pt) |
| NZ (1) | NZ596734A (pt) |
| RU (1) | RU2012101424A (pt) |
| WO (1) | WO2010147938A2 (pt) |
| ZA (1) | ZA201108706B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3250B1 (ar) | 2009-09-22 | 2018-09-16 | Novartis Ag | إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7 |
| RS59687B1 (sr) * | 2013-01-22 | 2020-01-31 | Vistagen Therapeutics Inc | Oblici doziranja i terapeutske primene l-4-hlorkinurenina |
| CN114533737B (zh) * | 2016-04-07 | 2024-05-31 | 奥伊斯特普安生物制药公司 | 治疗眼部病状的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7098331B2 (en) * | 2003-03-05 | 2006-08-29 | Targacept, Inc. | Arylvinylazacycloalkane compounds and methods of preparation and use thereof |
-
2010
- 2010-06-15 BR BRPI1014247A patent/BRPI1014247A2/pt not_active IP Right Cessation
- 2010-06-15 JP JP2012516189A patent/JP2012530707A/ja active Pending
- 2010-06-15 KR KR1020127000936A patent/KR20120061047A/ko not_active Withdrawn
- 2010-06-15 WO PCT/US2010/038605 patent/WO2010147938A2/en not_active Ceased
- 2010-06-15 EP EP10790028A patent/EP2442810A4/en not_active Withdrawn
- 2010-06-15 CA CA2763551A patent/CA2763551A1/en not_active Abandoned
- 2010-06-15 US US13/378,089 patent/US20120157477A1/en not_active Abandoned
- 2010-06-15 RU RU2012101424/15A patent/RU2012101424A/ru unknown
- 2010-06-15 MX MX2011013860A patent/MX2011013860A/es not_active Application Discontinuation
- 2010-06-15 NZ NZ596734A patent/NZ596734A/en not_active IP Right Cessation
- 2010-06-15 CN CN2010800267205A patent/CN102802630A/zh active Pending
- 2010-06-15 AU AU2010260265A patent/AU2010260265A1/en not_active Abandoned
-
2011
- 2011-11-17 IL IL216458A patent/IL216458A0/en unknown
- 2011-11-25 ZA ZA2011/08706A patent/ZA201108706B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120061047A (ko) | 2012-06-12 |
| IL216458A0 (en) | 2012-01-31 |
| ZA201108706B (en) | 2012-07-25 |
| EP2442810A4 (en) | 2012-11-28 |
| WO2010147938A2 (en) | 2010-12-23 |
| CN102802630A (zh) | 2012-11-28 |
| US20120157477A1 (en) | 2012-06-21 |
| MX2011013860A (es) | 2012-01-30 |
| WO2010147938A3 (en) | 2011-05-19 |
| AU2010260265A1 (en) | 2011-12-22 |
| CA2763551A1 (en) | 2010-12-23 |
| EP2442810A2 (en) | 2012-04-25 |
| JP2012530707A (ja) | 2012-12-06 |
| NZ596734A (en) | 2014-02-28 |
| RU2012101424A (ru) | 2013-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2372 DE 21-06-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |