BRPI1015927A2 - Kit e método para diagnosticar uma doença de tireoide e método para diagnosticar o hipotireoidismo, bem como célula e seu uso - Google Patents

Kit e método para diagnosticar uma doença de tireoide e método para diagnosticar o hipotireoidismo, bem como célula e seu uso

Info

Publication number
BRPI1015927A2
BRPI1015927A2 BRPI1015927-4A BRPI1015927A BRPI1015927A2 BR PI1015927 A2 BRPI1015927 A2 BR PI1015927A2 BR PI1015927 A BRPI1015927 A BR PI1015927A BR PI1015927 A2 BRPI1015927 A2 BR PI1015927A2
Authority
BR
Brazil
Prior art keywords
diagnosing
kit
cell
well
hypothyroidism
Prior art date
Application number
BRPI1015927-4A
Other languages
English (en)
Inventor
Naohiro Araki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BRPI1015927A2 publication Critical patent/BRPI1015927A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/046—Thyroid disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Physiology (AREA)
  • Reproductive Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
BRPI1015927-4A 2009-06-30 2010-06-24 Kit e método para diagnosticar uma doença de tireoide e método para diagnosticar o hipotireoidismo, bem como célula e seu uso BRPI1015927A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009155183 2009-06-30
PCT/JP2010/060731 WO2011001885A1 (ja) 2009-06-30 2010-06-24 甲状腺刺激ホルモンレセプターに対する抗体のバイオアッセイ法及び測定キットとこれらに用いる新規の遺伝子組み換え細胞

Publications (1)

Publication Number Publication Date
BRPI1015927A2 true BRPI1015927A2 (pt) 2015-09-01

Family

ID=43410960

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1015927-4A BRPI1015927A2 (pt) 2009-06-30 2010-06-24 Kit e método para diagnosticar uma doença de tireoide e método para diagnosticar o hipotireoidismo, bem como célula e seu uso

Country Status (10)

Country Link
US (3) US20120149036A1 (pt)
EP (2) EP2857497B1 (pt)
JP (3) JP5819192B2 (pt)
KR (1) KR101963904B1 (pt)
CN (1) CN102471760B (pt)
BR (1) BRPI1015927A2 (pt)
CA (1) CA2765558C (pt)
ES (2) ES2642262T3 (pt)
SG (3) SG10201912617UA (pt)
WO (1) WO2011001885A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012086756A1 (ja) * 2010-12-24 2012-06-28 大塚製薬株式会社 生理活性物質を検出するバイオアッセイ法
JP5903363B2 (ja) * 2012-10-10 2016-04-13 ヤマサ醤油株式会社 甲状腺刺激抗体測定における試料の前処理方法
WO2014108688A1 (en) * 2013-01-09 2014-07-17 Vantix Holdings Limited Ft4 electrochemical assay detection system
WO2016035677A1 (ja) * 2014-09-04 2016-03-10 大塚製薬株式会社 ｉｎ ｖｉｔｒｏサイクリックヌクレオチド測定の為のサンプルの前処理方法
JP5963984B2 (ja) * 2016-01-12 2016-08-03 ヤマサ醤油株式会社 甲状腺刺激抗体測定における試料の前処理方法
EP3828543B1 (en) * 2018-09-05 2024-04-03 Yamasa Corporation Method and kit for rapid measurement of autoantibody activity with respect to tsh receptor
US12546788B2 (en) * 2020-04-01 2026-02-10 Aska Pharmaceutical Co., Ltd. Methods for differentiating destructive thyroiditis from other pathological conditions
JP7212955B2 (ja) * 2020-12-28 2023-01-26 ヤマサ醤油株式会社 甲状腺刺激ホルモン受容体阻害性自己抗体の活性測定法およびキット
CN116731171B (zh) * 2023-05-26 2025-08-08 郑州伊美诺生物技术有限公司 rT3重组单克隆抗体制备方法及应用
WO2025100444A1 (ja) * 2023-11-07 2025-05-15 株式会社コスミックコーポレーション Ｔｓｈ活性測定用のレポーター細胞

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720693D0 (en) * 1997-09-30 1997-11-26 Univ Wales Medicine Assay
WO2009045292A1 (en) * 2007-10-01 2009-04-09 Diagnostic Hybrids, Inc. Sensitive and rapid methods of using chimeric receptors to identify autoimmune disease
US8563257B2 (en) * 2000-03-30 2013-10-22 Diagnostic Hybrids, Inc. Sensitive and rapid methods of using chimeric receptors to identify autoimmune disease and assess disease severity
JP3650815B2 (ja) 2000-11-22 2005-05-25 大学共同利用機関法人自然科学研究機構 緑色蛍光蛋白質の蛍光特性を制御することが可能なバイオセンサー蛋白質の作成方法、および前記方法により作成されるバイオセンサー蛋白質
DE10138876B4 (de) * 2001-08-08 2008-11-06 Forschungszentrum Jülich GmbH Genetisch modifizierte zyklisch-Nukleotid-gesteuerte lonenkanäle und deren Verwendung
DE10311769A1 (de) * 2003-03-18 2004-09-30 Bayer Healthcare Ag Testmethoden zur Bestimmung der intrazellulären Konzentration zyklischer Nukleotide
WO2005078445A1 (en) * 2004-02-12 2005-08-25 Institut Pasteur Non-invasive real-time in vivo bioluminescence imaging of local ca2+ dynamics in living organisms
JP2006204225A (ja) * 2005-01-31 2006-08-10 Tadashi Yoshida 細胞株の樹立方法
WO2007100618A2 (en) * 2006-02-23 2007-09-07 Atto Bioscience Novel cell-based phosphodiesterase assays
US20100159449A1 (en) * 2006-05-26 2010-06-24 Noacell Science Co., Ltd. Continuous Assay Method for Measuring Receptor- and Ion Channel-Mediated Calcium Response and Subsequent Gene Expression
JPWO2007142208A1 (ja) * 2006-06-05 2009-10-22 国立大学法人京都大学 温度感応タンパク質、ポリヌクレオチド、温度感応タンパク質発現プラスミド及び発現細胞、温度感応タンパク質の利用方法
WO2008118445A1 (en) * 2007-03-26 2008-10-02 Promega Corporation Methods to quench light from optical reactions
JP2009155183A (ja) 2007-12-27 2009-07-16 Taiheiyo Materials Corp カートリッジ型注入方式固着剤

Also Published As

Publication number Publication date
SG10201403310PA (en) 2014-10-30
ES2534330T3 (es) 2015-04-21
EP2857497B1 (en) 2017-09-06
JP2017192396A (ja) 2017-10-26
US20140072985A1 (en) 2014-03-13
HK1170526A1 (en) 2013-03-01
JPWO2011001885A1 (ja) 2012-12-13
WO2011001885A1 (ja) 2011-01-06
JP2016032472A (ja) 2016-03-10
CA2765558A1 (en) 2011-01-06
US20180259512A1 (en) 2018-09-13
HK1204650A1 (en) 2015-11-27
EP2450430B1 (en) 2015-03-18
US20120149036A1 (en) 2012-06-14
CN102471760B (zh) 2018-04-17
CA2765558C (en) 2018-09-25
SG10201912617UA (en) 2020-02-27
EP2450430A1 (en) 2012-05-09
EP2857497A1 (en) 2015-04-08
JP6472488B2 (ja) 2019-02-20
CN102471760A (zh) 2012-05-23
EP2450430A4 (en) 2013-02-27
ES2642262T3 (es) 2017-11-16
KR20120051657A (ko) 2012-05-22
JP5819192B2 (ja) 2015-11-18
KR101963904B1 (ko) 2019-03-29
SG176967A1 (en) 2012-01-30

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Legal Events

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 7.4 NA RPI NO 2475 DE 12/06/2018 POR TER SIDO INDEVIDA.

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements