CA1042988A - Chromatographe a ion double par colonnes paralleles - Google Patents

Chromatographe a ion double par colonnes paralleles

Info

Publication number: CA1042988A
Authority: CA; Canada
Prior art keywords: exchange resin; tubular column; stream; species; conductivity cell
Prior art date: 1974-11-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA230,456A

Other languages

English (en)

Inventor

Donald C. Benefiel

Albert R. Parrott

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Dow Chemical Co

Original Assignee

Dow Chemical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-11-12

Filing date

1975-06-30

Publication date

1978-11-21

1975-06-30 Application filed by Dow Chemical Co filed Critical Dow Chemical Co

1978-11-21 Application granted granted Critical

1978-11-21 Publication of CA1042988A publication Critical patent/CA1042988A/fr

Status Expired legal-status Critical Current

Links

230000009977 dual effect Effects 0.000 title description 3
239000000523 sample Substances 0.000 claims abstract description 40
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 30
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims abstract description 28
150000001450 anions Chemical class 0.000 claims abstract description 22
239000003456 ion exchange resin Substances 0.000 claims abstract description 22
229920003303 ion-exchange polymer Polymers 0.000 claims abstract description 22
150000001768 cations Chemical class 0.000 claims abstract description 17
239000003957 anion exchange resin Substances 0.000 claims abstract description 14
239000003729 cation exchange resin Substances 0.000 claims abstract description 13
239000012488 sample solution Substances 0.000 claims abstract description 13
150000002500 ions Chemical class 0.000 claims description 23
125000000129 anionic group Chemical group 0.000 claims description 11
125000002091 cationic group Chemical group 0.000 claims description 11
238000000034 method Methods 0.000 claims description 11
239000007864 aqueous solution Substances 0.000 claims description 9
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
239000007788 liquid Substances 0.000 claims description 4
239000000203 mixture Substances 0.000 claims description 4
238000002156 mixing Methods 0.000 claims description 2
238000002347 injection Methods 0.000 abstract description 8
239000007924 injection Substances 0.000 abstract description 8
238000005342 ion exchange Methods 0.000 abstract description 3
238000004445 quantitative analysis Methods 0.000 abstract description 3
239000011347 resin Substances 0.000 description 23
229920005989 resin Polymers 0.000 description 23
239000000243 solution Substances 0.000 description 11
241000894007 species Species 0.000 description 11
238000004458 analytical method Methods 0.000 description 8
230000000844 anti-bacterial effect Effects 0.000 description 6
238000000926 separation method Methods 0.000 description 6
239000012086 standard solution Substances 0.000 description 6
239000003899 bactericide agent Substances 0.000 description 5
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 3
MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
239000004793 Polystyrene Substances 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
239000002253 acid Substances 0.000 description 2
238000004587 chromatography analysis Methods 0.000 description 2
239000008367 deionised water Substances 0.000 description 2
229910021641 deionized water Inorganic materials 0.000 description 2
238000010828 elution Methods 0.000 description 2
-1 hydroxide ions Chemical class 0.000 description 2
229920001467 poly(styrenesulfonates) Polymers 0.000 description 2
229920002223 polystyrene Polymers 0.000 description 2
238000005070 sampling Methods 0.000 description 2
229910052708 sodium Inorganic materials 0.000 description 2
239000011734 sodium Substances 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
239000002699 waste material Substances 0.000 description 2
241000894006 Bacteria Species 0.000 description 1
LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
241000195493 Cryptophyta Species 0.000 description 1
FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
230000002353 algacidal effect Effects 0.000 description 1
229910021529 ammonia Inorganic materials 0.000 description 1
239000000908 ammonium hydroxide Substances 0.000 description 1
229940023913 cation exchange resins Drugs 0.000 description 1
230000036755 cellular response Effects 0.000 description 1
125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 description 1
238000013375 chromatographic separation Methods 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
238000001816 cooling Methods 0.000 description 1
238000012937 correction Methods 0.000 description 1
238000002242 deionisation method Methods 0.000 description 1
230000002939 deleterious effect Effects 0.000 description 1
238000001514 detection method Methods 0.000 description 1
239000012470 diluted sample Substances 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000012895 dilution Substances 0.000 description 1
229940116441 divinylbenzene Drugs 0.000 description 1
238000001914 filtration Methods 0.000 description 1
238000011010 flushing procedure Methods 0.000 description 1
239000011521 glass Substances 0.000 description 1
230000005484 gravity Effects 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
239000000463 material Substances 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
230000000748 slimicidal effect Effects 0.000 description 1
229910001415 sodium ion Inorganic materials 0.000 description 1
VQBIMXHWYSRDLF-UHFFFAOYSA-M sodium;azane;hydrogen carbonate Chemical compound [NH4+].[Na+].[O-]C([O-])=O VQBIMXHWYSRDLF-UHFFFAOYSA-M 0.000 description 1
239000000126 substance Substances 0.000 description 1
125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 description 1
230000001629 suppression Effects 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/466—Flow patterns using more than one column with separation columns in parallel
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/202—Injection using a sampling valve rotary valves
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/207—Injection using a sampling valve with metering cavity, e.g. sample loop
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/40—Flow patterns using back flushing
- G01N2030/402—Flow patterns using back flushing purging a device
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N2030/628—Multiplexing, i.e. several columns sharing a single detector
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
- G01N2030/965—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange suppressor columns

Landscapes

Physics & Mathematics (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)

CA230,456A 1974-11-12 1975-06-30 Chromatographe a ion double par colonnes paralleles Expired CA1042988A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US523091A US3923460A (en)	1974-11-12	1974-11-12	Dual ion chromatograph using parallel columns for ionic analysis

Publications (1)

Publication Number	Publication Date
CA1042988A true CA1042988A (fr)	1978-11-21

Family

ID=24083622

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA230,456A Expired CA1042988A (fr)	1974-11-12	1975-06-30	Chromatographe a ion double par colonnes paralleles

Country Status (2)

Country	Link
US (1)	US3923460A (fr)
CA (1)	CA1042988A (fr)

Families Citing this family (40)

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US4073725A (en) *	1975-05-09	1978-02-14	Hitachi, Ltd.	Method and apparatus for liquid chromatography under elevated pressure
JPS5460996A (en) *	1977-10-22	1979-05-16	Mitsubishi Chem Ind	Method of measuring amount of sugar
US4278507A (en) *	1977-12-13	1981-07-14	Antoine Derreumaux	Method for amperometric measurement of the free-chlorine content in a solution
US4199323A (en) *	1978-06-08	1980-04-22	The Dow Chemical Company	Analytical technique for quantitating acid/salt and base/salt samples for species concentration
US4314823A (en) *	1979-03-05	1982-02-09	Dionex Corporation	Combination apparatus and method for chromatographic separation and quantitative analysis of multiple ionic species
DE3027306A1 (de) *	1980-07-18	1982-02-18	Siemens AG, 1000 Berlin und 8000 München	Verfahren zur bestimmung des ph-wertes von ionenarmem wasser
US4359323A (en) *	1980-10-31	1982-11-16	W. R. Grace & Co.	Single pump liquid chromatograph analytical system for amines
US4631687A (en) *	1983-11-03	1986-12-23	Rohrback Technology Corporation	Method and apparatus for analysis employing multiple separation processes
US4629705A (en) *	1984-05-31	1986-12-16	The Dow Chemical Company	Indirect-photometric chromatography done in and with a variable capacity weakly basic or acidic ion exchange column
DE3442227A1 (de) *	1984-11-19	1986-05-28	Kernforschungsanlage Jülich GmbH, 5170 Jülich	Verfahren und vorrichtung zur ionenchromatographischen bestimmung des spurengehalts von waessrigen proben
US4849110A (en) *	1986-11-12	1989-07-18	Hitachi, Ltd.	Method and apparatus for liquid chromatography
US4872992A (en) *	1987-12-09	1989-10-10	Atlantic Richfield Company	Method and apparatus for analyzing diluted and undiluted fluid samples
US4950397A (en) *	1987-12-09	1990-08-21	Atlantic Richfield Company	Apparatus for analyzing diluted and undiluted fluid samples
US5443734A (en) *	1990-03-05	1995-08-22	Applied Separations, Inc.	Programmable solid phase extraction and elution device
US5071547A (en) *	1990-03-23	1991-12-10	Separations Technology, Inc.	Column chromatographic column apparatus with switching capability
US5073502A (en) *	1990-06-27	1991-12-17	United Technologies Corporation	Method and apparatus for analyzing total organic halogens
US5139734A (en) *	1990-11-26	1992-08-18	Westinghouse Electric Corp.	Resin processing system
US5468643A (en) *	1991-08-28	1995-11-21	The United States Of America As Represented By The Department Of Health And Human Services	Switching valve system for direct biological sample injection for LC analysis
US5377234A (en) *	1992-10-23	1994-12-27	General Electric Company	Colloidal resin slurry recycle concentrating system of nuclear reactor coolant water
EP0671002B2 (fr) *	1993-08-27	2002-01-16	Dionex Corporation	Chromatographie par echanges d'ions utilisant une regeneration frequente du suppresseur du type elution fractionnee
JP3302127B2 (ja) *	1993-09-17	2002-07-15	株式会社島津製作所	内燃機関用排出ガス自動分析装置
US5491096A (en) *	1993-12-27	1996-02-13	Eli Lilly And Company	Antigen detection with affinity chromatography and parallel processing a control
US5567307A (en) *	1994-09-30	1996-10-22	Lachat Instruments	System and a method for using a small suppressor column in performing liquid chromatography
ATE196949T1 (de) *	1995-03-03	2000-10-15	Alltech Associates Inc	Verfahren und vorrichtung zur elektrochemischen veränderung von chromatographiematerial
US5730866A (en) *	1996-07-19	1998-03-24	Delco Electronics Corporation	Automatic ionic cleanliness tester
US6019897A (en) *	1998-08-20	2000-02-01	Dyax Corporation	System for simultaneously pumping solvent for a plurality of chromatography columns
AU4450900A (en)	1999-04-23	2000-11-10	Advanced Bioanalytical Services, Inc.	High-throughput parallel liquid chromatography system
US6635173B2 (en) *	2000-12-28	2003-10-21	Cohesive Technologies, Inc.	Multi column chromatography system
US6755074B2 (en) *	2001-02-27	2004-06-29	Isco, Inc.	Liquid chromatographic method and system
US6904784B2 (en) *	2001-02-27	2005-06-14	Teledyne Isco, Inc.	Liquid chromatographic method and system
US6984734B2 (en) *	2002-02-26	2006-01-10	Board Of Regents, The University Of Texas System	Cyclo[n]pyrroles and methods thereto
WO2009111228A2 (fr) *	2008-02-29	2009-09-11	Waters Technologies Corporation	Surveillance chromatographique et commande de plusieurs flux de traitement
WO2010124159A1 (fr) *	2009-04-23	2010-10-28	Xcellerex, Inc.	Système et procédé pour charger un système de chromatographie à commande par rétroaction à vitesse variable
EP2667188B1 (fr)	2012-05-25	2021-06-23	Manol Roussev	Four pour colonnes de séparation
CN103076422B (zh) *	2013-01-11	2014-12-24	刘冠琳	一种多通道检测的离子色谱仪及其使用方法
JP6918555B2 (ja) *	2016-04-13	2021-08-11	株式会社堀場エステック	クロマトグラフ用サンプラ及びクロマトグラフ用サンプラの操作方法
CN106018637B (zh) *	2016-06-03	2018-06-05	四川大学	兼具低压离子色谱和低压流动注射分析的仪器及使用方法
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CN111077264B (zh) *	2020-01-03	2022-06-24	湖南金泰环保科技有限公司	实现单台离子色谱仪切换使用双系统的方法
CN113484459A (zh) *	2021-07-03	2021-10-08	上海纪本电子仪器有限公司	一种降雨在线监测系统

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US3416961A (en) *	1964-01-07	1968-12-17	Colonial Sugar Refining Co	Process for the separation of fructose and glucose

1974
- 1974-11-12 US US523091A patent/US3923460A/en not_active Expired - Lifetime
1975
- 1975-06-30 CA CA230,456A patent/CA1042988A/fr not_active Expired

Also Published As

Publication number	Publication date
US3923460A (en)	1975-12-02

Publication	Publication Date	Title
CA1042988A (fr)	1978-11-21	Chromatographe a ion double par colonnes paralleles
US3897213A (en)	1975-07-29	Automated quantitative analysis of ionic species
US3926559A (en)	1975-12-16	Method and apparatus for quantitative chromatographic analysis of cationic species
US3925019A (en)	1975-12-09	Chromatographic analysis of ionic species
US3920397A (en)	1975-11-18	Apparatus and method for quantitative analysis of ionic species by liquid column chromatography
US4849110A (en)	1989-07-18	Method and apparatus for liquid chromatography
JPS62223668A (ja)	1987-10-01	イオンクロマトグラフイ方法および装置
He et al.	2020	A high precision method for calcium determination in seawater using ion chromatography
GB2025060A (en)	1980-01-16	Analytical method for determining acid/salt and base/salt species concentration in solution
US5567307A (en)	1996-10-22	System and a method for using a small suppressor column in performing liquid chromatography
US4017262A (en)	1977-04-12	Chromatographic apparatus for analysis of ionic species
AU666667B2 (en)	1996-02-22	Liquide sample analyser
US3918906A (en)	1975-11-11	Determining total ionic content
US4567753A (en)	1986-02-04	Independent analysis of anions and cations using indirect photometric chromatography
US4290775A (en)	1981-09-22	Analytical method for determining acid/salt and base/salt species concentration in solution
d'Angelo et al.	1996	Fluoride, chloride, nitrate, and sulfate in aqueous solution by chemically suppressed ion chromatography
Tanaka et al.	1996	Acid rain monitoring by ion-exclusion-cation-exchange chromatography
US4679428A (en)	1987-07-14	Independent analysis of anions and cations using indirect photometric chromatography
WERNER	1962	Application of gas chromatography to sludge digestion gas analysis
CA1044824A (fr)	1978-12-19	Determination de la teneur globale en ions
JPS60111959A (ja)	1985-06-18	陰・陽イオンの同時分析方法
JPS6353509B2 (fr)	1988-10-24
Kieber et al.	1994	An Undergraduate Laboratory for the Determination of Sodium, Potassium, and Chloride: Using an Ion-Exchange Resin, Ion Chromatography, and Atomic Absorption Spectrophotometry
Niemann	1977	DONNAN EQUILIBRIUM APPLIED TO ENRICHMENT AND SPECIATION BY ION EXCHANGE FOR THE DETERMINATION OF SUBMICROMOLAR CATIONIC ACTIVITY.
Jay et al.	1985	The determination of common anion concentrations in surface and groundwater samples by eluent-suppressed ion chromatography