CA1049401A - Methode et appareil pour detecter les reactions immunologiques par diffusion dans un gel - Google Patents

Methode et appareil pour detecter les reactions immunologiques par diffusion dans un gel

Info

Publication number: CA1049401A
Authority: CA; Canada
Prior art keywords: gel; particles; metallized; biological particles; layer
Prior art date: 1974-04-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA221,157A

Other languages

English (en)

Other versions

CA221157S (en

Inventor

Ivar Giaever

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

General Electric Co

Original Assignee

General Electric Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-04-01

Filing date

1975-03-03

Publication date

1979-02-27

1974-04-01 Priority claimed from US05/457,093 external-priority patent/US3960490A/en

1975-03-03 Application filed by General Electric Co filed Critical General Electric Co

1979-02-27 Application granted granted Critical

1979-02-27 Publication of CA1049401A publication Critical patent/CA1049401A/fr

Status Expired legal-status Critical Current

Links

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239000002245 particle Substances 0.000 claims abstract description 127
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239000000499 gel Substances 0.000 claims description 90
239000000758 substrate Substances 0.000 claims description 34
229910052751 metal Inorganic materials 0.000 claims description 18
239000002184 metal Substances 0.000 claims description 18
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HKJKONMZMPUGHJ-UHFFFAOYSA-N 4-amino-5-hydroxy-3-[(4-nitrophenyl)diazenyl]-6-phenyldiazenylnaphthalene-2,7-disulfonic acid Chemical compound OS(=O)(=O)C1=CC2=CC(S(O)(=O)=O)=C(N=NC=3C=CC=CC=3)C(O)=C2C(N)=C1N=NC1=CC=C([N+]([O-])=O)C=C1 HKJKONMZMPUGHJ-UHFFFAOYSA-N 0.000 description 1
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UOACKFBJUYNSLK-XRKIENNPSA-N Estradiol Cypionate Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H](C4=CC=C(O)C=C4CC3)CC[C@@]21C)C(=O)CCC1CCCC1 UOACKFBJUYNSLK-XRKIENNPSA-N 0.000 description 1
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WZOZCAZYAWIWQO-UHFFFAOYSA-N [Ni].[Ni]=O Chemical compound [Ni].[Ni]=O WZOZCAZYAWIWQO-UHFFFAOYSA-N 0.000 description 1
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229920000642 polymer Polymers 0.000 description 1
230000035935 pregnancy Effects 0.000 description 1
229940070376 protein Drugs 0.000 description 1
238000012113 quantitative test Methods 0.000 description 1
239000012429 reaction media Substances 0.000 description 1
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238000007789 sealing Methods 0.000 description 1
239000011343 solid material Substances 0.000 description 1
238000006467 substitution reaction Methods 0.000 description 1
208000006379 syphilis Diseases 0.000 description 1
229910052715 tantalum Inorganic materials 0.000 description 1
GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
239000010409 thin film Substances 0.000 description 1
210000002700 urine Anatomy 0.000 description 1
238000005406 washing Methods 0.000 description 1

Landscapes

Investigating Or Analysing Biological Materials (AREA)

CA221,157A 1974-04-01 1975-03-03 Methode et appareil pour detecter les reactions immunologiques par diffusion dans un gel Expired CA1049401A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/457,093 US3960490A (en)	1974-04-01	1974-04-01	Method and apparatus for detecting immunologic reactions by diffusion in gel

Publications (1)

Publication Number	Publication Date
CA1049401A true CA1049401A (fr)	1979-02-27

Family

ID=23815407

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA221,157A Expired CA1049401A (fr)	1974-04-01	1975-03-03	Methode et appareil pour detecter les reactions immunologiques par diffusion dans un gel

Country Status (1)

Country	Link
CA (1)	CA1049401A (fr)

1975
- 1975-03-03 CA CA221,157A patent/CA1049401A/fr not_active Expired

Publication	Publication Date	Title
US3960490A (en)	1976-06-01	Method and apparatus for detecting immunologic reactions by diffusion in gel
US3926564A (en)	1975-12-16	Substrate for immunological tests and method of fabrication thereof
US3960488A (en)	1976-06-01	Method and apparatus for quantitative surface inhibition test
CA1303981C (fr)	1992-06-23	Structures optiques recouvertes d'un polymere
US4092116A (en)	1978-05-30	Method for binding antibodies to a surface such that they remain active
US4054646A (en)	1977-10-18	Method and apparatus for detection of antibodies and antigens
US5089387A (en)	1992-02-18	Dna probe diffraction assay and reagents
US3979184A (en)	1976-09-07	Diagnostic device for visually detecting presence of biological particles
US4794089A (en)	1988-12-27	Method for electronic detection of a binding reaction
US5212060A (en)	1993-05-18	Dry test strip comprising a dextran barrier for excluding erythrocytes
US3979509A (en)	1976-09-07	Opaque layer method for detecting biological particles
JP2818292B2 (ja)	1998-10-30	分析物検定方法及び素子
US4011308A (en)	1977-03-08	Method for surface immunological detection of biological particles by the use of tagged antibodies
US4689310A (en)	1987-08-25	Methods for attaching ligands or anti-ligands to a solid phase
FR2638848A1 (fr)	1990-05-11	Procede de detection et/ou de dosage dans un milieu liquide ou semi-liquide d'au moins une substance organique, biologique ou medicamenteuse soluble, par une methode d'agglutination
US4791069A (en)	1988-12-13	Methods for attaching ligands or anti-ligands to a solid phase
US5422283A (en)	1995-06-06	Solid-phase interferometric immunoassay system
SE439550B (sv)	1985-06-17	Forfarande vid immunodiffusion eller immunoelektrofores
CA1302244C (fr)	1992-06-02	Bandelettes reactives seches presentant une couche excluant les erythrocites et empechant que ceux-ci masquent la presence de l'analyte
JPS5916669B2 (ja)	1984-04-17	抗原又は抗体の検出方法
CA1049401A (fr)	1979-02-27	Methode et appareil pour detecter les reactions immunologiques par diffusion dans un gel
JPS5944583B2 (ja)	1984-10-30	蛋白質の検出法
US4668637A (en)	1987-05-26	Method for detecting and dosing by erythroadsorption a biological substance
CA1049398A (fr)	1979-02-27	Methode et appareil pour detecter les particules biologiques ayant des proprietes immunologiques
CA1048409A (fr)	1979-02-13	Methode pour ameliorer le contraste dans les epreuves immunologiques avec des proteines a grosses molecules