CA1067487A - Analogues de gonadotrophines (lh-rh) et produits intermediaires - Google Patents

Analogues de gonadotrophines (lh-rh) et produits intermediaires

Info

Publication number
CA1067487A
CA1067487A CA 322018 CA322018A CA1067487A CA 1067487 A CA1067487 A CA 1067487A CA 322018 CA322018 CA 322018 CA 322018 A CA322018 A CA 322018A CA 1067487 A CA1067487 A CA 1067487A
Authority
CA
Canada
Prior art keywords
leu
ser
group
trp
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA 322018
Other languages
English (en)
Inventor
Andrew V. Schally
David H. Coy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Tulane University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/586,436 external-priority patent/US4018726A/en
Priority claimed from US05/586,437 external-priority patent/US4010125A/en
Priority claimed from US05/652,945 external-priority patent/US4024121A/en
Application filed by Tulane University filed Critical Tulane University
Application granted granted Critical
Publication of CA1067487A publication Critical patent/CA1067487A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/28—Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA 322018 1975-06-12 1979-02-21 Analogues de gonadotrophines (lh-rh) et produits intermediaires Expired CA1067487A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/586,436 US4018726A (en) 1975-06-12 1975-06-12 [D-Phe6 ]-LH-RH and intermediates therefor
US05/586,437 US4010125A (en) 1975-06-12 1975-06-12 [D-Trp6 ]-LH-RH and intermediates therefor
US05/652,945 US4024121A (en) 1976-01-27 1976-01-27 (Pyro)-Glu-His-Trp-D-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHR and intermediates

Publications (1)

Publication Number Publication Date
CA1067487A true CA1067487A (fr) 1979-12-04

Family

ID=27416479

Family Applications (2)

Application Number Title Priority Date Filing Date
CA254,039A Expired CA1065859A (fr) 1975-06-12 1976-06-04 Analogues lh-rh et produits intermediaires
CA 322018 Expired CA1067487A (fr) 1975-06-12 1979-02-21 Analogues de gonadotrophines (lh-rh) et produits intermediaires

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA254,039A Expired CA1065859A (fr) 1975-06-12 1976-06-04 Analogues lh-rh et produits intermediaires

Country Status (11)

Country Link
JP (1) JPS6022720B2 (fr)
AU (1) AU500087B2 (fr)
BE (1) BE842857A (fr)
CA (2) CA1065859A (fr)
CH (1) CH615662A5 (fr)
DE (1) DE2625843C2 (fr)
FR (1) FR2313940A1 (fr)
GB (1) GB1535602A (fr)
HK (1) HK61079A (fr)
NZ (1) NZ181036A (fr)
SE (1) SE427031B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2450109B1 (fr) * 1977-11-08 1986-03-28 Roussel Uclaf Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes
DE2905502C2 (de) * 1979-02-14 1982-07-15 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS58125819U (ja) * 1982-02-19 1983-08-26 名伸電機株式会社 積算電力量計用パツキン
FI832053L (fi) * 1982-06-10 1983-12-11 Syntex Inc Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
CH661206A5 (fr) * 1983-09-23 1987-07-15 Debiopharm Sa Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
HU193093B (en) * 1985-04-16 1987-08-28 Innofinance Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation
CA2029018A1 (fr) * 1989-11-01 1991-05-02 Robert P. Millar Analogues de l'hormone liberant de la gonadotrophine
DE4342092B4 (de) * 1993-12-09 2007-01-11 Zentaris Gmbh Langwirkende Injektionssuspension und Verfahren zur Herstellung
FR2713933B1 (fr) * 1993-12-16 1996-02-02 Rhone Merieux Méthode de superovulation des femelles bovines, méthode de mise en anoestrus et kit approprié.
CA2192773C (fr) 1995-12-15 2008-09-23 Hiroaki Okada Obtention d'une preparation a liberation prolongee pour injection
CA2192782C (fr) 1995-12-15 2008-10-14 Nobuyuki Takechi Production de microsphere
US7812044B2 (en) 2001-11-13 2010-10-12 Takeda Pharmaceutical Company Limited Anticancer agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5726506A (en) * 1980-07-25 1982-02-12 Iseki Agricult Mach Nursery plant transplanter

Also Published As

Publication number Publication date
DE2625843A1 (de) 1976-12-23
AU500087B2 (en) 1979-05-10
NZ181036A (en) 1978-12-18
FR2313940B1 (fr) 1979-04-20
GB1535602A (en) 1978-12-13
JPS5231073A (en) 1977-03-09
FR2313940A1 (fr) 1977-01-07
SE7606692L (sv) 1976-12-13
CA1065859A (fr) 1979-11-06
SE427031B (sv) 1983-02-28
AU1452476A (en) 1977-12-08
DE2625843C2 (de) 1985-03-28
BE842857A (fr) 1976-12-13
CH615662A5 (en) 1980-02-15
JPS6022720B2 (ja) 1985-06-03
HK61079A (en) 1979-09-07

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