CA1077392A - Polymer coated refractory particles as immunoadsorbent - Google Patents

Polymer coated refractory particles as immunoadsorbent

Info

Publication number: CA1077392A
Authority: CA; Canada
Prior art keywords: antigen; bound; immunoadsorbent; antibodies; polymer
Prior art date: 1975-04-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA248,664A

Other languages

English (en)

French (fr)

Inventor

Lavell R. Johnson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Becton Dickinson and Co

Original Assignee

Becton Dickinson and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-04-07

Filing date

1976-03-24

Publication date

1980-05-13

1975-04-07 Priority claimed from US05/565,848 external-priority patent/US4059685A/en

1976-03-24 Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co

1979-02-09 Priority to CA321,151A priority Critical patent/CA1083934A/en

1980-05-13 Application granted granted Critical

1980-05-13 Publication of CA1077392A publication Critical patent/CA1077392A/en

Status Expired legal-status Critical Current

Links

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229960001348 estriol Drugs 0.000 description 1
PROQIPRRNZUXQM-ZXXIGWHRSA-N estriol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)C4)O)[C@@H]4[C@@H]3CCC2=C1 PROQIPRRNZUXQM-ZXXIGWHRSA-N 0.000 description 1
IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 1
230000002349 favourable effect Effects 0.000 description 1
238000011049 filling Methods 0.000 description 1
229960000304 folic acid Drugs 0.000 description 1
239000011724 folic acid Substances 0.000 description 1
235000019152 folic acid Nutrition 0.000 description 1
229940095886 glucagen Drugs 0.000 description 1
RKGLLHCSSVJTAN-YYICOITRSA-N glucagen Chemical compound Cl.C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 RKGLLHCSSVJTAN-YYICOITRSA-N 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
239000000122 growth hormone Substances 0.000 description 1
229960000890 hydrocortisone Drugs 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
230000003100 immobilizing effect Effects 0.000 description 1
230000001900 immune effect Effects 0.000 description 1
230000006872 improvement Effects 0.000 description 1
229910010272 inorganic material Inorganic materials 0.000 description 1
239000011147 inorganic material Substances 0.000 description 1
238000009434 installation Methods 0.000 description 1
229940125396 insulin Drugs 0.000 description 1
229940079322 interferon Drugs 0.000 description 1
230000007774 longterm Effects 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
230000000873 masking effect Effects 0.000 description 1
239000011325 microbead Substances 0.000 description 1
238000002156 mixing Methods 0.000 description 1
208000013651 non-24-hour sleep-wake syndrome Diseases 0.000 description 1
230000000269 nucleophilic effect Effects 0.000 description 1
229920001778 nylon Polymers 0.000 description 1
239000000199 parathyroid hormone Substances 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
229920001155 polypropylene Polymers 0.000 description 1
229920001343 polytetrafluoroethylene Polymers 0.000 description 1
239000004810 polytetrafluoroethylene Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000002335 preservative effect Effects 0.000 description 1
239000000186 progesterone Substances 0.000 description 1
229960003387 progesterone Drugs 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 description 1
230000005855 radiation Effects 0.000 description 1
238000009790 rate-determining step (RDS) Methods 0.000 description 1
239000000376 reactant Substances 0.000 description 1
238000011084 recovery Methods 0.000 description 1
230000002829 reductive effect Effects 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
CSMWJXBSXGUPGY-UHFFFAOYSA-L sodium dithionate Chemical compound [Na+].[Na+].[O-]S(=O)(=O)S([O-])(=O)=O CSMWJXBSXGUPGY-UHFFFAOYSA-L 0.000 description 1
229940075931 sodium dithionate Drugs 0.000 description 1
JVBXVOWTABLYPX-UHFFFAOYSA-L sodium dithionite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])=O JVBXVOWTABLYPX-UHFFFAOYSA-L 0.000 description 1
230000009870 specific binding Effects 0.000 description 1
229960003604 testosterone Drugs 0.000 description 1
ZCUFMDLYAMJYST-UHFFFAOYSA-N thorium dioxide Chemical compound O=[Th]=O ZCUFMDLYAMJYST-UHFFFAOYSA-N 0.000 description 1
239000005495 thyroid hormone Substances 0.000 description 1
229940036555 thyroid hormone Drugs 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
238000012546 transfer Methods 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
239000011800 void material Substances 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Sampling And Sample Adjustment (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)

CA248,664A 1975-04-07 1976-03-24 Polymer coated refractory particles as immunoadsorbent Expired CA1077392A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA321,151A CA1083934A (en)	1975-04-07	1979-02-09	Chamber holder for an immobilized immunoadsorbent

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/565,848 US4059685A (en)	1973-03-19	1975-04-07	Immobilized immunoadsorbent

Publications (1)

Publication Number	Publication Date
CA1077392A true CA1077392A (en)	1980-05-13

Family

ID=24260359

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA248,664A Expired CA1077392A (en)	1975-04-07	1976-03-24	Polymer coated refractory particles as immunoadsorbent

Country Status (8)

Country	Link
JP (1)	JPS5916671B2 (it)
CA (1)	CA1077392A (it)
DE (1)	DE2660445C2 (it)
DK (1)	DK147809C (it)
GB (1)	GB1527264A (it)
IT (1)	IT1063860B (it)
SE (2)	SE441309B (it)
ZA (1)	ZA761751B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS56147070A (en) *	1980-04-17	1981-11-14	Olympus Optical Co Ltd	Reaction container for discrete type automatic biochemical analyzer
JPS57131062A (en) *	1981-02-05	1982-08-13	Amano Pharmaceut Co Ltd	Quantitative determination of antigen using enzyme- labelled antigen and second antibody insolubilizing carrier
AU551103B2 (en) *	1981-02-13	1986-04-17	Becton Dickinson & Company	Reusable assay for multisite antigens
JPS58225354A (ja) *	1982-06-24	1983-12-27	Olympus Optical Co Ltd	免疫分析法
JPS5921385A (ja) *	1982-07-27	1984-02-03	Sekisui Chem Co Ltd	固定化酵素カ−トリツジ
US4458020A (en) *	1982-11-15	1984-07-03	Quidel	Integrated single tube plunger immunoassay system having plural reagent chambers
JPS607363A (ja) *	1983-06-27	1985-01-16	Sekisui Chem Co Ltd	抗原もしくは抗体の測定方法
JPS60501570A (ja) *	1983-11-08	1985-09-19	クイデル	迅速プランジヤ−免疫学的検定法及び装置
JPS61127768U (it) *	1985-01-30	1986-08-11
US4948561A (en) *	1989-02-09	1990-08-14	Eastman Kodak Company	Multiple level filter device and kit containing same
DE102004006470B4 (de) *	2004-02-06	2006-06-01	Senova Gesellschaft für Biowissenschaft und Technik mbH	Absorptionsphotometrisches Verfahren zur quantitativen Stoffanalyse
US7968061B2 (en) *	2004-10-18	2011-06-28	Becton, Dickinson And Company	Microplate with dialysis membrane

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA990416A (en) *	1972-04-19	1976-06-01	Sieuwko J. Mantel	Device suitable for use in radioimmunoassay and method of determining the content of a specific hormone in a serum sample
CA1036935A (en) *	1973-03-19	1978-08-22	Lavell R. Johnson	Method and apparatus for radioimmunoassay with regeneration of immunadsorbent

1976
- 1976-03-22 ZA ZA761751A patent/ZA761751B/xx unknown
- 1976-03-23 GB GB11660/76A patent/GB1527264A/en not_active Expired
- 1976-03-24 CA CA248,664A patent/CA1077392A/en not_active Expired
- 1976-03-26 DE DE2660445A patent/DE2660445C2/de not_active Expired
- 1976-04-06 IT IT21971/76A patent/IT1063860B/it active
- 1976-04-07 JP JP51038302A patent/JPS5916671B2/ja not_active Expired
- 1976-04-07 SE SE7604097A patent/SE441309B/xx not_active IP Right Cessation
- 1976-04-07 DK DK164876A patent/DK147809C/da active Protection Beyond IP Right Term
1980
- 1980-01-28 SE SE8000662A patent/SE437193B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
GB1527264A (en)	1978-10-04
DE2660445C2 (de)	1982-04-01
ZA761751B (en)	1977-03-30
SE7604097L (sv)	1976-12-10
SE8000662L (sv)	1980-01-28
JPS5916671B2 (ja)	1984-04-17
IT1063860B (it)	1985-02-18
SE437193B (sv)	1985-02-11
SE441309B (sv)	1985-09-23
DK147809C (da)	1985-08-12
JPS51123819A (en)	1976-10-28
DK147809B (da)	1984-12-10
DK164876A (da)	1976-10-08

Legal Events

Date	Code	Title	Description
1997-05-13	MKEX	Expiry

Publication	Publication Date	Title
US4059685A (en)	1977-11-22	Immobilized immunoadsorbent
US4180383A (en)	1979-12-25	Chamber holder for immobilized immunoadsorbent
US4166102A (en)	1979-08-28	Immobilized immunoadsorbent
CA1077392A (en)	1980-05-13	Polymer coated refractory particles as immunoadsorbent
US4278651A (en)	1981-07-14	Supported receptor and use thereof in an assay
US4433059A (en)	1984-02-21	Double antibody conjugate
US3652761A (en)	1972-03-28	Immunochemical composites and antigen or antibody purification therewith
US4695392A (en)	1987-09-22	Magnetic particles for use in separations
US4478946A (en)	1984-10-23	Carrier bound immunosorbent
US4698302A (en)	1987-10-06	Enzymatic reactions using magnetic particles
CA1226215A (en)	1987-09-01	Immunoassay of antigens
US4672040A (en)	1987-06-09	Magnetic particles for use in separations
US4695393A (en)	1987-09-22	Magnetic particles for use in separations
US4628037A (en)	1986-12-09	Binding assays employing magnetic particles
Sportsman et al.	1980	Chromatographic properties of silica-immobilized antibodies
US4108976A (en)	1978-08-22	Automated direct serum radioimmunoassay
EP0140489A1 (en)	1985-05-08	Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances
IL45707A (en)	1977-01-31	Method of detecting antigens or antibodies
WO1988006632A1 (en)	1988-09-07	Magnetic particles for use in separations
US4108975A (en)	1978-08-22	Radioimmunoassay system
JPH09500446A (ja)	1997-01-14	液状放射性廃棄物からの放射性標識された生物学的分子の除去方法
Davis et al.	1986	Evaluation of immunosorbents for the analysis of small molecules: isolation and purification of cytokinins
FI68468C (fi)	1985-09-10	Direkt agglutineringstest foer paovisning av antigener i kroppsvaetskor
Akkaya et al.	2012	Concanavalin A immobilized magnetic poly (glycidyl methacrylate) beads for antibody purification
US4223002A (en)	1980-09-16	Isolation of alpha1 -fetoprotein