CA1090785A - Derives peptidiques et procede de preparation - Google Patents

Derives peptidiques et procede de preparation

Info

Publication number: CA1090785A
Authority: CA; Canada
Prior art keywords: formula; methyl; group; compound; carbon atom
Prior art date: 1976-05-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA278,276A

Other languages

English (en)

Inventor

Frank R. Atherton

Michael J. Hall

Cedric H. Hassall

Peter S. Ringrose

Robert W. Lambert

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-05-14

Filing date

1977-05-12

Publication date

1980-12-02

1977-05-12 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

1980-12-02 Application granted granted Critical

1980-12-02 Publication of CA1090785A publication Critical patent/CA1090785A/fr

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CA278,276A 1976-05-14 1977-05-12 Derives peptidiques et procede de preparation Expired CA1090785A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB20014/76		1976-05-14
GB20014/76A GB1577232A (en)	1976-05-14	1976-05-14	Peptide derivatives of phosphonic and phosphinic acids

Publications (1)

Publication Number	Publication Date
CA1090785A true CA1090785A (fr)	1980-12-02

Family

ID=10138919

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA278,276A Expired CA1090785A (fr)	1976-05-14	1977-05-12	Derives peptidiques et procede de preparation

Country Status (23)

Country	Link
JP (1)	JPS52139023A (fr)
AT (1)	AT355740B (fr)
AU (1)	AU511452B2 (fr)
BE (1)	BE854591A (fr)
CA (1)	CA1090785A (fr)
DE (1)	DE2721760A1 (fr)
DK (1)	DK209877A (fr)
ES (1)	ES458748A1 (fr)
FI (1)	FI771518A7 (fr)
FR (1)	FR2351124A1 (fr)
GB (1)	GB1577232A (fr)
GR (1)	GR73010B (fr)
IL (1)	IL52040A (fr)
IT (1)	IT1075484B (fr)
LU (1)	LU77319A1 (fr)
MC (1)	MC1146A1 (fr)
NL (1)	NL7704370A (fr)
NO (1)	NO771717L (fr)
NZ (1)	NZ184047A (fr)
PH (1)	PH14715A (fr)
PT (1)	PT66544B (fr)
SE (1)	SE7705628L (fr)
ZA (1)	ZA772732B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0002039A1 (fr) *	1977-11-19	1979-05-30	Ciba-Geigy Ag	Dérivés d'acides phosphoneux, procédés pour leur préparation et leur utilisation dans la lutte contre les micro-organismes
EP0010067B1 (fr) *	1978-10-05	1983-08-31	Ciba-Geigy Ag	Procédé pour influencer la croissance des plantes
DE3368418D1 (en) *	1982-09-17	1987-01-29	Kyowa Hakko Kogyo Kk	Phosphorus-containing peptide derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS51639B1 (fr) *	1971-07-28	1976-01-09
IL48835A (en) *	1975-01-27	1979-05-31	Sparamedica Ag	Amino acyl and peptidyl derivatives of phophonic acids, their preparation and pharmaceutical compositions containingthem

1976
- 1976-05-14 GB GB20014/76A patent/GB1577232A/en not_active Expired
1977
- 1977-04-21 NL NL7704370A patent/NL7704370A/xx not_active Application Discontinuation
- 1977-04-29 IT IT23054/77A patent/IT1075484B/it active
- 1977-05-06 IL IL52040A patent/IL52040A/xx unknown
- 1977-05-06 ZA ZA00772732A patent/ZA772732B/xx unknown
- 1977-05-09 AU AU25008/77A patent/AU511452B2/en not_active Expired
- 1977-05-09 NZ NZ184047A patent/NZ184047A/xx unknown
- 1977-05-10 PH PH19754A patent/PH14715A/en unknown
- 1977-05-12 CA CA278,276A patent/CA1090785A/fr not_active Expired
- 1977-05-12 LU LU77319A patent/LU77319A1/xx unknown
- 1977-05-12 FI FI771518A patent/FI771518A7/fi not_active Application Discontinuation
- 1977-05-12 FR FR7714549A patent/FR2351124A1/fr active Granted
- 1977-05-13 AT AT345877A patent/AT355740B/de not_active IP Right Cessation
- 1977-05-13 SE SE7705628A patent/SE7705628L/xx unknown
- 1977-05-13 BE BE177536A patent/BE854591A/fr unknown
- 1977-05-13 GR GR53459A patent/GR73010B/el unknown
- 1977-05-13 JP JP5447577A patent/JPS52139023A/ja active Pending
- 1977-05-13 DK DK209877A patent/DK209877A/da unknown
- 1977-05-13 NO NO771717A patent/NO771717L/no unknown
- 1977-05-13 PT PT66544A patent/PT66544B/pt unknown
- 1977-05-13 MC MC771242A patent/MC1146A1/fr unknown
- 1977-05-13 ES ES458748A patent/ES458748A1/es not_active Expired
- 1977-05-13 DE DE19772721760 patent/DE2721760A1/de not_active Withdrawn

Also Published As

Publication number	Publication date
PT66544A (en)	1977-06-01
IT1075484B (it)	1985-04-22
SE7705628L (sv)	1977-11-15
BE854591A (fr)	1977-11-14
FR2351124B1 (fr)	1981-02-13
FI771518A7 (fr)	1977-11-15
AT355740B (de)	1980-03-25
GR73010B (fr)	1984-01-24
NO771717L (no)	1977-11-15
IL52040A (en)	1979-11-30
AU2500877A (en)	1978-11-16
PT66544B (en)	1979-04-12
NZ184047A (en)	1980-04-28
GB1577232A (en)	1980-10-22
PH14715A (en)	1981-11-13
JPS52139023A (en)	1977-11-19
FR2351124A1 (fr)	1977-12-09
ATA345877A (de)	1979-08-15
NL7704370A (nl)	1977-11-16
LU77319A1 (fr)	1978-06-26
ES458748A1 (es)	1978-03-01
DE2721760A1 (de)	1977-12-01
MC1146A1 (fr)	1978-01-30
ZA772732B (en)	1978-04-26
AU511452B2 (en)	1980-08-21
IL52040A0 (en)	1977-07-31
DK209877A (da)	1977-11-15

Legal Events

Date	Code	Title	Description
1997-12-02	MKEX	Expiry

Publication	Publication Date	Title
US4016148A (en)	1977-04-05	Peptide derivatives of phosphonic and phosphinic acids and intermediates therefor
SE452326B (sv)	1987-11-23	Salter av agmatinderivat och farmaceutiska preparat innehallande desamma
GB2210043A (en)	1989-06-01	Phosphinylcycloalkylcarbonyl and phosphinylcycloalkenylcarbonyl dipeptides
US4298523A (en)	1981-11-03	Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4128542A (en)	1978-12-05	Peptide derivatives
GB2086912A (en)	1982-05-19	Enkephalin derivatives production thereof and pharmaceutical compositions
EP0030847B1 (fr)	1984-05-30	Peptides à activité pharmacologique, leur préparation et compositions pharmaceutiques les contenant
EP0030848B1 (fr)	1985-02-13	Peptides à activité pharmacologique, leur préparation et compositions pharmaceutiques les contenant
CA1090785A (fr)	1980-12-02	Derives peptidiques et procede de preparation
US4143134A (en)	1979-03-06	Halo-phosphonopeptides
EP0030846B1 (fr)	1984-05-09	Peptides à activité pharmacologique, leur préparation et compositions pharmaceutiques les contenant
US4320051A (en)	1982-03-16	Analgesic tripeptide amides
CS199708B2 (en)	1980-07-31	Method of producing polypeptides and derivatives thereof having effect similar morphine
EP0109142B1 (fr)	1988-09-28	Dérivés de peptides et de pseudopeptides
US4421744A (en)	1983-12-20	Aminoacyl derivatives
US4369137A (en)	1983-01-18	N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide
IE881803L (en)	1988-12-16	New tripeptide derivatives having a polycyclic nitrogenous¹structure, process of the preparation thereof and¹pharmaceutical compositions containing them
EP0122018B1 (fr)	1987-09-02	Dérivés tripeptides à activité pharmaceutique
US3272790A (en)	1966-09-13	Polypeptides
US4351763A (en)	1982-09-28	Pharmacologically active peptides
US5276137A (en)	1994-01-04	Analgesic peptides with a trifluoronorvaline modification
NO784285L (no)	1979-06-21	Peptid-derivater og fremstilling av disse
US3793304A (en)	1974-02-19	Cyclic decapeptides comprising an l-tyrosine radical
CA1060798A (fr)	1979-08-21	Composes
GB2027433A (en)	1980-02-20	Aminoalkanoylaminoalkyl Phosphonic Acids