CA1120925A - Antitumor anthracycline antibiotics - Google Patents

Antitumor anthracycline antibiotics

Info

Publication number
CA1120925A
CA1120925A CA000308532A CA308532A CA1120925A CA 1120925 A CA1120925 A CA 1120925A CA 000308532 A CA000308532 A CA 000308532A CA 308532 A CA308532 A CA 308532A CA 1120925 A CA1120925 A CA 1120925A
Authority
CA
Canada
Prior art keywords
addition salt
acid addition
group
product
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000308532A
Other languages
English (en)
French (fr)
Inventor
Hamao Umezawa
Tomio Takeuchi
Hiroshi Naganawa
Kuniaki Tatsuta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Application granted granted Critical
Publication of CA1120925A publication Critical patent/CA1120925A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA000308532A 1977-08-05 1978-08-01 Antitumor anthracycline antibiotics Expired CA1120925A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP52-94348 1977-08-05
JP9434877A JPS5430146A (en) 1977-08-05 1977-08-05 Novel anthracycline derivatives and their preparation

Publications (1)

Publication Number Publication Date
CA1120925A true CA1120925A (en) 1982-03-30

Family

ID=14107771

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000308532A Expired CA1120925A (en) 1977-08-05 1978-08-01 Antitumor anthracycline antibiotics

Country Status (19)

Country Link
JP (1) JPS5430146A (da)
AT (1) AT361622B (da)
AU (1) AU510946B2 (da)
BE (1) BE869395A (da)
CA (1) CA1120925A (da)
DE (1) DE2831579C3 (da)
DK (1) DK152677C (da)
ES (1) ES472306A1 (da)
FI (1) FI63420C (da)
FR (1) FR2399439A1 (da)
GB (1) GB2002754B (da)
GR (1) GR63951B (da)
HK (1) HK18683A (da)
IE (1) IE47252B1 (da)
IT (1) IT1160574B (da)
NL (1) NL174147C (da)
SE (1) SE443565B (da)
SG (1) SG5383G (da)
ZA (1) ZA784033B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK160616C (da) * 1979-02-03 1991-09-02 Zaidan Hojin Biseibutsu Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf
JPS56156300A (en) * 1980-04-26 1981-12-02 Microbial Chem Res Found Novel preparative method of anthracyclin derivative
JPS6016998A (ja) * 1983-07-07 1985-01-28 Microbial Chem Res Found アントラサイクリン誘導体の製造方法
JPS6083171U (ja) * 1983-11-15 1985-06-08 タキゲン製造株式会社 蝶番
JPS63227599A (ja) * 1987-03-14 1988-09-21 Kirin Brewery Co Ltd アンスラサイクリン化合物およびその用途
DE19544532C2 (de) * 1995-11-29 1997-12-11 Pharma Dynamics Gmbh Verfahren zum Herstellen eines Doxorubicin-Lyophilisats
KR19990084528A (ko) * 1998-05-07 1999-12-06 박상철 신규 안트라사이클린 유도체 및 제조방법
GB2530001B (en) 2014-06-17 2019-01-16 Gw Pharma Ltd Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy
GB2531282A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
GB2539472A (en) 2015-06-17 2016-12-21 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2568929A (en) 2017-12-01 2019-06-05 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB201806953D0 (en) 2018-04-27 2018-06-13 Gw Res Ltd Cannabidiol Preparations

Also Published As

Publication number Publication date
IT1160574B (it) 1987-03-11
ZA784033B (en) 1979-07-25
FI782388A7 (fi) 1979-02-06
GR63951B (en) 1980-01-16
FI63420B (fi) 1983-02-28
DK152677B (da) 1988-04-11
JPS5430146A (en) 1979-03-06
AT361622B (de) 1981-03-25
DE2831579A1 (de) 1979-02-15
GB2002754A (en) 1979-02-28
AU510946B2 (en) 1980-07-24
AU3844678A (en) 1980-01-31
DE2831579B2 (de) 1980-01-24
BE869395A (fr) 1978-11-16
IT7868847A0 (it) 1978-08-03
NL7807906A (nl) 1979-02-07
DK343878A (da) 1979-02-06
HK18683A (en) 1983-06-10
FI63420C (fi) 1983-06-10
DE2831579C3 (de) 1980-09-18
NL174147B (nl) 1983-12-01
SE7808304L (sv) 1979-02-06
JPS5647194B2 (da) 1981-11-07
ES472306A1 (es) 1979-10-01
IE781566L (en) 1979-02-05
GB2002754B (en) 1982-02-10
IE47252B1 (en) 1984-02-08
ATA561278A (de) 1980-08-15
DK152677C (da) 1988-10-24
SE443565B (sv) 1986-03-03
NL174147C (nl) 1984-05-01
FR2399439A1 (fr) 1979-03-02
SG5383G (en) 1983-09-09
FR2399439B1 (da) 1981-07-17

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Legal Events

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