CA1122503A - Epreuve immunochimique a l'aide de reactifs marques - Google Patents

Epreuve immunochimique a l'aide de reactifs marques

Info

Publication number: CA1122503A
Authority: CA; Canada
Prior art keywords: reagent; reactance; immune; receptor; test
Prior art date: 1977-11-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA315,018A

Other languages

English (en)

Inventor

Richard C. Ebersole

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

EIDP Inc

Original Assignee

EI Du Pont de Nemours and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-03

Filing date

1978-10-31

Publication date

1982-04-27

1978-09-18 Priority claimed from US05/942,261 external-priority patent/US4219335A/en

1978-10-31 Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co

1982-04-27 Application granted granted Critical

1982-04-27 Publication of CA1122503A publication Critical patent/CA1122503A/fr

Status Expired legal-status Critical Current

Links

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238000012360 testing method Methods 0.000 title claims description 66
230000000984 immunochemical effect Effects 0.000 title description 2
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XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 9
PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 8
238000001514 detection method Methods 0.000 claims description 6
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102000014914 Carrier Proteins Human genes 0.000 description 1
108010078791 Carrier Proteins Proteins 0.000 description 1
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
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102000006395 Globulins Human genes 0.000 description 1
108010044091 Globulins Proteins 0.000 description 1
230000005355 Hall effect Effects 0.000 description 1
241000709721 Hepatovirus A Species 0.000 description 1
108060003951 Immunoglobulin Proteins 0.000 description 1
102000004856 Lectins Human genes 0.000 description 1
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241000701076 Macacine alphaherpesvirus 1 Species 0.000 description 1
239000005041 Mylar™ Substances 0.000 description 1
XNPOFXIBHOVFFH-UHFFFAOYSA-N N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide Chemical compound C1CCCCC1N=C=NCCN1CCOCC1 XNPOFXIBHOVFFH-UHFFFAOYSA-N 0.000 description 1
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QXZUUHYBWMWJHK-UHFFFAOYSA-N [Co].[Ni] Chemical compound [Co].[Ni] QXZUUHYBWMWJHK-UHFFFAOYSA-N 0.000 description 1
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XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
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230000007423 decrease Effects 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000000151 deposition Methods 0.000 description 1
LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
238000005538 encapsulation Methods 0.000 description 1
YYXLGGIKSIZHSF-UHFFFAOYSA-N ethene;furan-2,5-dione Chemical compound C=C.O=C1OC(=O)C=C1 YYXLGGIKSIZHSF-UHFFFAOYSA-N 0.000 description 1
230000005294 ferromagnetic effect Effects 0.000 description 1
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239000012634 fragment Substances 0.000 description 1
208000005252 hepatitis A Diseases 0.000 description 1
125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
230000008105 immune reaction Effects 0.000 description 1
102000018358 immunoglobulin Human genes 0.000 description 1
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230000002452 interceptive effect Effects 0.000 description 1
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UQSXHKLRYXJYBZ-UHFFFAOYSA-N iron oxide Inorganic materials [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 1
235000013980 iron oxide Nutrition 0.000 description 1
VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical class [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 description 1
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NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
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PCCVSPMFGIFTHU-UHFFFAOYSA-N tetracyanoquinodimethane Chemical compound N#CC(C#N)=C1C=CC(=C(C#N)C#N)C=C1 PCCVSPMFGIFTHU-UHFFFAOYSA-N 0.000 description 1
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Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

CA315,018A 1977-11-03 1978-10-31 Epreuve immunochimique a l'aide de reactifs marques Expired CA1122503A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US84821777A	1977-11-03	1977-11-03
US05/942,261 US4219335A (en)	1978-09-18	1978-09-18	Immunochemical testing using tagged reagents
US942,261		1978-09-18
US848,217		1992-03-10

Publications (1)

Publication Number	Publication Date
CA1122503A true CA1122503A (fr)	1982-04-27

Family

ID=27126757

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA315,018A Expired CA1122503A (fr)	1977-11-03	1978-10-31	Epreuve immunochimique a l'aide de reactifs marques

Country Status (16)

Country	Link
JP (1)	JPS5912139B2 (fr)
AU (1)	AU522995B2 (fr)
CA (1)	CA1122503A (fr)
CH (1)	CH638052A5 (fr)
DE (1)	DE2847282A1 (fr)
DK (1)	DK489678A (fr)
FI (1)	FI783346A7 (fr)
FR (1)	FR2408142A1 (fr)
GB (1)	GB2008767B (fr)
IE (1)	IE47482B1 (fr)
IL (1)	IL55856A (fr)
IT (1)	IT1101280B (fr)
LU (1)	LU80471A1 (fr)
NL (1)	NL7810910A (fr)
NO (1)	NO151099C (fr)
SE (1)	SE431257B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2136130B (en) *	1983-02-28	1987-02-11	Theodore Henry Krueger	Chemical assay systems and methods
CA1220818A (fr) *	1983-05-05	1987-04-21	Hugh A.O. Hill	Methodes d'essais biologiques utilisant des agents de liaison specifiques
GB8314523D0 (en) *	1983-05-25	1983-06-29	Lowe C R	Diagnostic device
EP0139373A1 (fr) *	1983-08-26	1985-05-02	The Regents Of The University Of California	Système pour immunoessais multiples
JPS6055265A (ja) *	1983-09-06	1985-03-30	Fujirebio Inc	磁性粒子を用いた抗原、抗体の測定方法
GB8331514D0 (en) *	1983-11-25	1984-01-04	Janssen Pharmaceutica Nv	Visualization method
AU596946B2 (en) *	1984-07-10	1990-05-24	F. Hoffmann-La Roche Ltd	Methods of assay
FI844027A7 (fi) *	1984-10-12	1986-04-13	Labsystems Oy	Immunologiskt bestaemningsfoerfarande.
JPH0823558B2 (ja) *	1984-11-27	1996-03-06	オ−ジエニクスリミテツド	検定装置
LU86239A1 (fr) *	1986-01-02	1987-09-03	Sanders Probel Lab	Methode de detection d'agents reactifs et moyens de mise en oeuvre de cette methode
US4794089A (en) *	1986-03-25	1988-12-27	Midwest Research Microscopy, Inc.	Method for electronic detection of a binding reaction
US5374524A (en) *	1988-05-10	1994-12-20	E. I. Du Pont De Nemours And Company	Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5137804A (en) *	1988-05-10	1992-08-11	E. I. Du Pont De Nemours And Company	Assay device and immunoassay
GB2270976A (en) *	1992-09-18	1994-03-30	Marconi Gec Ltd	Immunoassay/separation process using an auxiliary species on a support
RU2225985C2 (ru) *	1998-09-08	2004-03-20	Тиботек Н.В.	Способ быстрого скрининга анализируемых проб
US6544480B1 (en)	1999-10-26	2003-04-08	Tibotec Bvba	Device and related method for dispensing small volumes of liquid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1479661A (en) *	1972-06-26	1977-07-13	Gen Electric	Method and apparatus for detection and purification of proteins and antibodies
GB1500127A (en) *	1973-10-10	1978-02-08	Abbott Lab	Reactive matrices
US4020151A (en) *	1976-02-17	1977-04-26	International Diagnostic Technology, Inc.	Method for quantitation of antigens or antibodies on a solid surface
IL49685A (en) *	1976-05-31	1978-10-31	Technion Res & Dev Foundation	Specific binding assay method for determining the concentration of materials and reagent means therefor
US4087248A (en) *	1976-07-26	1978-05-02	Miles Laughton E	Multiple assay machine and method

1978
- 1978-10-03 SE SE7810351A patent/SE431257B/sv not_active IP Right Cessation
- 1978-10-31 DE DE19782847282 patent/DE2847282A1/de not_active Withdrawn
- 1978-10-31 CA CA315,018A patent/CA1122503A/fr not_active Expired
- 1978-11-01 GB GB7842707A patent/GB2008767B/en not_active Expired
- 1978-11-01 CH CH1125478A patent/CH638052A5/de not_active IP Right Cessation
- 1978-11-02 IL IL55856A patent/IL55856A/xx unknown
- 1978-11-02 FR FR7831041A patent/FR2408142A1/fr active Granted
- 1978-11-02 AU AU41283/78A patent/AU522995B2/en not_active Expired
- 1978-11-02 IE IE2168/78A patent/IE47482B1/en unknown
- 1978-11-02 IT IT7829378A patent/IT1101280B/it active
- 1978-11-02 FI FI783346A patent/FI783346A7/fi unknown
- 1978-11-02 JP JP53134678A patent/JPS5912139B2/ja not_active Expired
- 1978-11-02 DK DK489678A patent/DK489678A/da not_active Application Discontinuation
- 1978-11-02 NL NL7810910A patent/NL7810910A/xx not_active Application Discontinuation
- 1978-11-02 NO NO783691A patent/NO151099C/no unknown
- 1978-11-03 LU LU80471A patent/LU80471A1/fr unknown

Also Published As

Publication number	Publication date
JPS5491296A (en)	1979-07-19
NL7810910A (nl)	1979-05-07
JPS5912139B2 (ja)	1984-03-21
FR2408142A1 (fr)	1979-06-01
IE47482B1 (en)	1984-04-04
FR2408142B1 (fr)	1984-02-17
NO151099B (no)	1984-10-29
GB2008767B (en)	1982-06-30
NO783691L (no)	1979-05-04
SE7810351L (sv)	1979-05-04
DE2847282A1 (de)	1979-05-10
SE431257B (sv)	1984-01-23
IL55856A0 (en)	1979-01-31
IT1101280B (it)	1985-09-28
DK489678A (da)	1979-05-04
LU80471A1 (fr)	1979-06-15
AU522995B2 (en)	1982-07-08
IT7829378A0 (it)	1978-11-02
IE782168L (en)	1980-03-18
FI783346A7 (fi)	1979-05-04
NO151099C (no)	1985-02-06
GB2008767A (en)	1979-06-06
CH638052A5 (de)	1983-08-31
AU4128378A (en)	1979-05-17
IL55856A (en)	1981-11-30

Legal Events

Date	Code	Title	Description
1999-04-27	MKEX	Expiry

Publication	Publication Date	Title
US4219335A (en)	1980-08-26	Immunochemical testing using tagged reagents
CA1122503A (fr)	1982-04-27	Epreuve immunochimique a l'aide de reactifs marques
JP4324212B2 (ja)	2009-09-02	磁気応答性試薬を使用する磁気補助結合アッセイ
RU2176393C2 (ru)	2001-11-27	Способ и соединения для магниторелаксометрического обнаружения аналитов и их применение
US6294342B1 (en)	2001-09-25	Magnetically assisted binding assays utilizing a magnetically responsive reagent
Richardson et al.	2001	The use of coated paramagnetic particles as a physical label in a magneto-immunoassay
EP0154734B1 (fr)	1990-08-29	Essai pour la détection immédiate d'un ligand, trousse d'essai et sa préparation
US4067959A (en)	1978-01-10	Indirect solid surface test for antigens or antibodies
JP4171139B2 (ja)	2008-10-22	磁性体標識による免疫検査方法とその装置
JP2002509242A (ja)	2002-03-26	力識別検定
EP0082862B1 (fr)	1986-01-29	Procede de detection ou de determination de l'histamine dans des materiaux contenant de l'histamine, notamment des fluides du corps et moyens analytiques utilises dans ce procede
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