CA1127536A - Procede d'identification des infections a virus au moyen d'anticorps et de bacteries - Google Patents

Procede d'identification des infections a virus au moyen d'anticorps et de bacteries

Info

Publication number: CA1127536A
Authority: CA; Canada
Prior art keywords: antibody; bacteria; cells; sample; bound
Prior art date: 1978-10-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA337,922A

Other languages

English (en)

Inventor

Alice S. Huang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Harvard University

Original Assignee

Harvard University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-10-19

Filing date

1979-10-18

Publication date

1982-07-13

1979-10-18 Application filed by Harvard University filed Critical Harvard University

1982-07-13 Application granted granted Critical

1982-07-13 Publication of CA1127536A publication Critical patent/CA1127536A/fr

Status Expired legal-status Critical Current

Links

241000894006 Bacteria Species 0.000 title claims abstract description 43
230000003612 virological effect Effects 0.000 title description 6
208000015181 infectious disease Diseases 0.000 title description 5
210000004027 cell Anatomy 0.000 claims abstract description 64
241000700605 Viruses Species 0.000 claims abstract description 29
238000001727 in vivo Methods 0.000 claims abstract description 15
208000036142 Viral infection Diseases 0.000 claims abstract description 14
230000009385 viral infection Effects 0.000 claims abstract description 14
239000000523 sample Substances 0.000 claims description 26
239000013068 control sample Substances 0.000 claims description 21
238000000034 method Methods 0.000 claims description 18
108060003951 Immunoglobulin Proteins 0.000 claims description 9
102000018358 immunoglobulin Human genes 0.000 claims description 9
241000191967 Staphylococcus aureus Species 0.000 claims description 8
XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 claims description 3
208000002606 Paramyxoviridae Infections Diseases 0.000 claims description 3
239000012678 infectious agent Substances 0.000 claims description 3
230000000241 respiratory effect Effects 0.000 claims description 3
210000002345 respiratory system Anatomy 0.000 claims description 3
208000003265 stomatitis Diseases 0.000 claims description 3
208000005925 vesicular stomatitis Diseases 0.000 claims description 3
230000000007 visual effect Effects 0.000 claims description 3
239000011541 reaction mixture Substances 0.000 claims 1
238000011534 incubation Methods 0.000 abstract description 9
230000036046 immunoreaction Effects 0.000 abstract description 2
238000000926 separation method Methods 0.000 abstract description 2
210000002966 serum Anatomy 0.000 description 7
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
241001465754 Metazoa Species 0.000 description 4
241000283973 Oryctolagus cuniculus Species 0.000 description 4
239000000872 buffer Substances 0.000 description 4
238000003745 diagnosis Methods 0.000 description 4
238000010790 dilution Methods 0.000 description 4
239000012895 dilution Substances 0.000 description 4
239000000203 mixture Substances 0.000 description 4
241000699800 Cricetinae Species 0.000 description 3
SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 3
239000006285 cell suspension Substances 0.000 description 3
238000001035 drying Methods 0.000 description 3
239000000725 suspension Substances 0.000 description 3
102000018697 Membrane Proteins Human genes 0.000 description 2
108010052285 Membrane Proteins Proteins 0.000 description 2
230000000569 anti-influenzal effect Effects 0.000 description 2
239000000834 fixative Substances 0.000 description 2
238000010438 heat treatment Methods 0.000 description 2
210000005260 human cell Anatomy 0.000 description 2
238000005406 washing Methods 0.000 description 2
102000019260 B-Cell Antigen Receptors Human genes 0.000 description 1
108010012919 B-Cell Antigen Receptors Proteins 0.000 description 1
241000282693 Cercopithecidae Species 0.000 description 1
241001517310 Eria Species 0.000 description 1
102000006395 Globulins Human genes 0.000 description 1
108010044091 Globulins Proteins 0.000 description 1
208000009889 Herpes Simplex Diseases 0.000 description 1
241001494479 Pecora Species 0.000 description 1
241000725643 Respiratory syncytial virus Species 0.000 description 1
241000700584 Simplexvirus Species 0.000 description 1
239000007983 Tris buffer Substances 0.000 description 1
241000711975 Vesicular stomatitis virus Species 0.000 description 1
239000000427 antigen Substances 0.000 description 1
102000036639 antigens Human genes 0.000 description 1
108091007433 antigens Proteins 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
238000003556 assay Methods 0.000 description 1
239000012620 biological material Substances 0.000 description 1
230000000740 bleeding effect Effects 0.000 description 1
239000013592 cell lysate Substances 0.000 description 1
239000003599 detergent Substances 0.000 description 1
239000011521 glass Substances 0.000 description 1
238000003306 harvesting Methods 0.000 description 1
238000007654 immersion Methods 0.000 description 1
229940072221 immunoglobulins Drugs 0.000 description 1
238000001114 immunoprecipitation Methods 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
230000002458 infectious effect Effects 0.000 description 1
210000003292 kidney cell Anatomy 0.000 description 1
239000003550 marker Substances 0.000 description 1
WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
238000006386 neutralization reaction Methods 0.000 description 1
238000002135 phase contrast microscopy Methods 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
238000007790 scraping Methods 0.000 description 1
230000028327 secretion Effects 0.000 description 1
239000000243 solution Substances 0.000 description 1
241000894007 species Species 0.000 description 1
238000004114 suspension culture Methods 0.000 description 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
241000712461 unidentified influenza virus Species 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/586—Liposomes, microcapsules or cells

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Wood Science & Technology (AREA)
Food Science & Technology (AREA)
Pathology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Biophysics (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

CA337,922A 1978-10-19 1979-10-18 Procede d'identification des infections a virus au moyen d'anticorps et de bacteries Expired CA1127536A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US95271978A	1978-10-19	1978-10-19
US952,719		1978-10-19
US7943879A	1979-09-27	1979-09-27
US79,438		1979-09-27

Publications (1)

Publication Number	Publication Date
CA1127536A true CA1127536A (fr)	1982-07-13

Family

ID=26762008

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA337,922A Expired CA1127536A (fr)	1978-10-19	1979-10-18	Procede d'identification des infections a virus au moyen d'anticorps et de bacteries

Country Status (5)

Country	Link
CA (1)	CA1127536A (fr)
DE (1)	DE2941575A1 (fr)
FR (1)	FR2439233A1 (fr)
GB (1)	GB2034464B (fr)
SE (1)	SE7908656L (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL66733A (en) *	1982-09-07	1986-03-31	Yeda Res & Dev	Assay for ifn and kit therefor
EP0143107B1 (fr) *	1983-10-26	1988-08-17	Jürgen Dr. Lembke	Méthode pour la détection de virus dans des cultures pures d'organismes microscopiques ainsi que dans des comestibles et dans des produits technologiques
SE466623B (sv) *	1989-06-01	1992-03-09	Karobio Ab	Saett och testsats foer diagnosticering av en aktiv infektion
GB8919230D0 (en) *	1989-08-24	1989-10-04	Vaccine Research Foundation Li	Method for in vivo testing of immunity in non-human subjects
CN114384244B (zh) *	2021-11-11	2024-12-10	北京英诺特生物技术股份有限公司	直接免疫荧光检测试剂盒的制备方法、试剂盒及联检方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1562804A (en) *	1972-06-26	1980-03-19	Gen Electric	Detection of antibodies and antigens
DE2322562C2 (de) *	1972-11-06	1984-03-29	Pharmacia AB, Uppsala	Verfahren zur Bestimmung von Antigenen in einer Probe

1979
- 1979-10-13 DE DE19792941575 patent/DE2941575A1/de not_active Withdrawn
- 1979-10-15 GB GB7935776A patent/GB2034464B/en not_active Expired
- 1979-10-18 SE SE7908656A patent/SE7908656L/ not_active Application Discontinuation
- 1979-10-18 CA CA337,922A patent/CA1127536A/fr not_active Expired
- 1979-10-19 FR FR7926072A patent/FR2439233A1/fr active Granted

Also Published As

Publication number	Publication date
SE7908656L (sv)	1980-04-20
GB2034464A (en)	1980-06-04
FR2439233B1 (fr)	1985-03-08
GB2034464B (en)	1983-05-25
DE2941575A1 (de)	1980-04-30
FR2439233A1 (fr)	1980-05-16

Legal Events

Date	Code	Title	Description
1999-07-13	MKEX	Expiry

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EP0355099B2 (fr)	1996-12-04	Procede d'analyse d'immunoglobulines
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US5155022A (en)	1992-10-13	Assay for lyme disease
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US5773232A (en)	1998-06-30	Methods for measurement of lymphocyte function
IE63426B1 (en)	1995-04-19	Immunometric assay kit and method applicable to whole cells
CA1127536A (fr)	1982-07-13	Procede d'identification des infections a virus au moyen d'anticorps et de bacteries
CA2076592A1 (fr)	1993-04-09	Methode, test et trousse pour dosage d'un ligand specifique a l'aide d'une membrane filtrante a debit controle
JP4268358B2 (ja)	2009-05-27	抗体および免疫学的測定方法
US4474877A (en)	1984-10-02	Process for detection and measurement of viral specific immunoglobulins and article of manufacture therefor
JPH0326965A (ja)	1991-02-05	表面水酸基を有する膜を用いるクラミジア抗原の測定のための診断用試験キット及び方法
US4814269A (en)	1989-03-21	Diagnostic testing for antibodies against microorganisms
US20070160978A1 (en)	2007-07-12	Method for seriological diagnosis and determination of immunisation status, comprising various controls
EP1340085B1 (fr)	2008-07-30	Analyse permettant de detecter directement une cellule biologique dans un echantillon de fluide corporel
US4382076A (en)	1983-05-03	Hepatitis A antibody assay
US7169571B2 (en)	2007-01-30	Methods for measurement of lymphocyte function
JPH09127114A (ja)	1997-05-16	免疫学的測定用安定化ＩｇＭ試薬
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LU500582B1 (en)	2022-02-28	Muscovy Duck Parvovirus POCT Test Strip, Preparation Method Therefor and Application Thereof
Ueno et al.	1991	Serological assessment of chlamydial infection in the koala by a slide EIA technique
ES2321289T3 (es)	2009-06-04	Metodo de diagnostico serologico.
US5756302A (en)	1998-05-26	Human herpesvirus 6 detection assay