CA1134764A - Production de codeine a partir de cultures de cellules de pavot - Google Patents

Production de codeine a partir de cultures de cellules de pavot

Info

Publication number
CA1134764A
CA1134764A CA000324565A CA324565A CA1134764A CA 1134764 A CA1134764 A CA 1134764A CA 000324565 A CA000324565 A CA 000324565A CA 324565 A CA324565 A CA 324565A CA 1134764 A CA1134764 A CA 1134764A
Authority
CA
Canada
Prior art keywords
cells
codeine
growth
culture
cytodifferentiated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000324565A
Other languages
English (en)
Inventor
Wolfgang W.G. Kurz
Friedrich Constabel
W.H. John Tam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Council of Canada
Original Assignee
National Research Council of Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Council of Canada filed Critical National Research Council of Canada
Priority to CA000324565A priority Critical patent/CA1134764A/fr
Priority to GB8006252A priority patent/GB2045243B/en
Priority to DE19803007400 priority patent/DE3007400A1/de
Priority to JP3574180A priority patent/JPS55127994A/ja
Priority to CH220080A priority patent/CH644634A5/fr
Priority to IT67426/80A priority patent/IT1147722B/it
Application granted granted Critical
Publication of CA1134764A publication Critical patent/CA1134764A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/91—Cell lines ; Processes using cell lines

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA000324565A 1979-03-21 1979-03-21 Production de codeine a partir de cultures de cellules de pavot Expired CA1134764A (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA000324565A CA1134764A (fr) 1979-03-21 1979-03-21 Production de codeine a partir de cultures de cellules de pavot
GB8006252A GB2045243B (en) 1979-03-21 1980-02-25 Producing codeine from cell cultures
DE19803007400 DE3007400A1 (de) 1979-03-21 1980-02-27 Verfahren zur herstellung von codein aus pflanzenzellenkulturen
JP3574180A JPS55127994A (en) 1979-03-21 1980-03-19 Codeine production from plant cell culture
CH220080A CH644634A5 (fr) 1979-03-21 1980-03-20 Procede pour la production de codeine.
IT67426/80A IT1147722B (it) 1979-03-21 1980-03-21 Procedimento per la produzione di codeina da culture di cellule

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000324565A CA1134764A (fr) 1979-03-21 1979-03-21 Production de codeine a partir de cultures de cellules de pavot

Publications (1)

Publication Number Publication Date
CA1134764A true CA1134764A (fr) 1982-11-02

Family

ID=4113882

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000324565A Expired CA1134764A (fr) 1979-03-21 1979-03-21 Production de codeine a partir de cultures de cellules de pavot

Country Status (6)

Country Link
JP (1) JPS55127994A (fr)
CA (1) CA1134764A (fr)
CH (1) CH644634A5 (fr)
DE (1) DE3007400A1 (fr)
GB (1) GB2045243B (fr)
IT (1) IT1147722B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492404A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Procede de production ou de biotransformation de metabolites par des cellules vegetales in vitro

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4114314A (en) * 1977-02-22 1978-09-19 The Ministry Of Science & Higher Education Process for the production of thebaine

Also Published As

Publication number Publication date
JPS5718875B2 (fr) 1982-04-19
DE3007400A1 (de) 1980-11-20
GB2045243A (en) 1980-10-29
GB2045243B (en) 1983-09-14
CH644634A5 (fr) 1984-08-15
JPS55127994A (en) 1980-10-03
IT8067426A0 (it) 1980-03-21
IT1147722B (it) 1986-11-26

Similar Documents

Publication Publication Date Title
Hashimoto et al. Tropane alkaloid production in Hyoscyamus root cultures
US5019504A (en) Production of taxol or taxol-like compounds in cell culture
Yamada et al. Tropane alkaloid production in cultured cells of Duboisia leichhardtii
Staba et al. Alkaloid production from Papaver tissue cultures
US4152214A (en) Production of homodeoxyharringtonine and other cephalotaxine esters by tissue culture
CA1134764A (fr) Production de codeine a partir de cultures de cellules de pavot
EP0331404A2 (fr) Méthode pour produire des alcaloides du tropane
Kamo et al. Morphinan alkaloids: biosynthesis in plant (Papaver spp.) tissue cultures
JP4563493B2 (ja) ナフトキノン系抗がん活性成分の効率的製造
JP2703783B2 (ja) トリテルペノイドの生産方法
JPH01124383A (ja) 植物の組織培養方法
JPH01240194A (ja) トロパン系アルカロイドの生産方法
JPH0220291A (ja) トロパン系アルカロイドの生産方法
JPH0414960B2 (fr)
JPH08196269A (ja) 薬用ニンジンカルスの培養方法
CN106995828B (zh) 利用喜树悬浮细胞生产n1-乙酰犬尿胺的方法
JPH01300890A (ja) トロパン系アルカロイド高生産細胞およびその取得方法
CN116694549A (zh) 高密度培养山莨菪悬浮细胞产生东莨菪碱的方法
JPS60227673A (ja) アキカラマツ培養細胞の選抜方法
JPS61205482A (ja) アキカラマツの組織培養方法
JPS6232880A (ja) キンポウゲ科植物の組織培養方法
JP2001269191A (ja) 生物学的に活性なフェノール系化合物（＋）カテキンの生産方法
KAMO¹ et al. II. 5 Morphinan Alkaloids: Biosynthesis in Plant
Petri et al. Regeneration Ability and Alkaloid Production in Tissue Cultures of Datura innoxia
JPH02117393A (ja) トロパン系アルカロイドの生産方法

Legal Events

Date Code Title Description
MKEX Expiry