CA1178956A - Cephalosporin analogs - Google Patents

Cephalosporin analogs

Info

Publication number
CA1178956A
CA1178956A CA000324074A CA324074A CA1178956A CA 1178956 A CA1178956 A CA 1178956A CA 000324074 A CA000324074 A CA 000324074A CA 324074 A CA324074 A CA 324074A CA 1178956 A CA1178956 A CA 1178956A
Authority
CA
Canada
Prior art keywords
group
cis
oct
azabicyclo
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000324074A
Other languages
English (en)
French (fr)
Inventor
Tadashi Hirata
Takehiro Ogasa
Hiromitsu Saito
Nobuhiro Nakamizo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3469678A external-priority patent/JPS54128591A/ja
Priority claimed from JP12240278A external-priority patent/JPS5549375A/ja
Priority claimed from JP12702778A external-priority patent/JPS5553290A/ja
Priority claimed from JP13307178A external-priority patent/JPS5559185A/ja
Priority claimed from JP53162007A external-priority patent/JPS5936915B2/ja
Priority claimed from JP16200678A external-priority patent/JPS5587789A/ja
Priority claimed from JP54008409A external-priority patent/JPS5936917B2/ja
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of CA1178956A publication Critical patent/CA1178956A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000324074A 1978-03-25 1979-03-23 Cephalosporin analogs Expired CA1178956A (en)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
JP34696/78 1978-03-25
JP3469678A JPS54128591A (en) 1978-03-25 1978-03-25 Cephalosporin analog
JP12240278A JPS5549375A (en) 1978-10-04 1978-10-04 Cephalosporin analog
JP122402/78 1978-10-04
JP127027/78 1978-10-16
JP12702778A JPS5553290A (en) 1978-10-16 1978-10-16 Cephalosporin analogue
JP13307178A JPS5559185A (en) 1978-10-28 1978-10-28 Cephalosporin analog
JP133071/78 1978-10-28
JP162007/78 1978-12-26
JP162006/78 1978-12-26
JP53162007A JPS5936915B2 (ja) 1978-12-26 1978-12-26 セフアロスポリン類縁体
JP16200678A JPS5587789A (en) 1978-12-26 1978-12-26 Sephalosporin analog
JP8409/79 1979-01-27
JP54008409A JPS5936917B2 (ja) 1979-01-27 1979-01-27 セフアロスポリン類縁体

Publications (1)

Publication Number Publication Date
CA1178956A true CA1178956A (en) 1984-12-04

Family

ID=27563451

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000324074A Expired CA1178956A (en) 1978-03-25 1979-03-23 Cephalosporin analogs

Country Status (10)

Country Link
AU (1) AU527128B2 (da)
CA (1) CA1178956A (da)
CH (1) CH640855A5 (da)
DE (1) DE2911787C2 (da)
DK (1) DK120179A (da)
FR (1) FR2420538A1 (da)
GB (1) GB2017103B (da)
IT (1) IT1165187B (da)
NL (1) NL7902321A (da)
NO (1) NO790956L (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671092A (en) * 1979-11-14 1981-06-13 Kyowa Hakko Kogyo Co Ltd Optical active cephalosporin analogous derivative
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
US4708956A (en) * 1985-12-12 1987-11-24 Kyowa Hakko Kogyo Co., Ltd. 3-position halogenated cephalosporin analogs and pharmaceutical compositions
JPH0791291B2 (ja) * 1985-12-30 1995-10-04 イ−ライ・リリ−・アンド・カンパニ− １−カルバセフアロスポリン抗生物質

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4140688A (en) * 1978-04-03 1979-02-20 Smithkline Corporation Tricyclic (azeto-isoquinoline) β-lactams

Also Published As

Publication number Publication date
DE2911787A1 (de) 1979-09-27
IT7967623A0 (it) 1979-03-26
FR2420538B1 (da) 1982-10-15
GB2017103B (en) 1982-09-08
DE2911787C2 (de) 1985-06-05
GB2017103A (en) 1979-10-03
NO790956L (no) 1979-09-26
FR2420538A1 (fr) 1979-10-19
AU527128B2 (en) 1983-02-17
IT1165187B (it) 1987-04-22
DK120179A (da) 1979-09-26
AU4536879A (en) 1979-10-04
CH640855A5 (de) 1984-01-31
NL7902321A (nl) 1979-09-27

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Legal Events

Date Code Title Description
MKEX Expiry