CA1209048A - Composes de spiro-hydantoine pour inhiber l'aldose reductase - Google Patents

Composes de spiro-hydantoine pour inhiber l'aldose reductase

Info

Publication number
CA1209048A
CA1209048A CA000480349A CA480349A CA1209048A CA 1209048 A CA1209048 A CA 1209048A CA 000480349 A CA000480349 A CA 000480349A CA 480349 A CA480349 A CA 480349A CA 1209048 A CA1209048 A CA 1209048A
Authority
CA
Canada
Prior art keywords
spiro
fluoro
dione
racemic
sarges
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000480349A
Other languages
English (en)
Inventor
Billie M. York Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/368,631 external-priority patent/US4438272A/en
Priority claimed from US06/368,630 external-priority patent/US4436745A/en
Priority claimed from CA000425866A external-priority patent/CA1200247A/fr
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Priority to CA000480349A priority Critical patent/CA1209048A/fr
Application granted granted Critical
Publication of CA1209048A publication Critical patent/CA1209048A/fr
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000480349A 1982-04-15 1985-04-29 Composes de spiro-hydantoine pour inhiber l'aldose reductase Expired CA1209048A (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000480349A CA1209048A (fr) 1982-04-15 1985-04-29 Composes de spiro-hydantoine pour inhiber l'aldose reductase

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US36863282A 1982-04-15 1982-04-15
US368,632 1982-04-15
US06/368,631 US4438272A (en) 1982-04-15 1982-04-15 Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
US06/368,630 US4436745A (en) 1982-04-15 1982-04-15 Method of inhibiting aldose reductase activity
US368,630 1982-04-15
US368,631 1982-04-15
CA000425866A CA1200247A (fr) 1982-04-15 1983-04-14 Inhibition de l'activite de l'aldose reductase; compositions utilisees a cette fin et methode de preparation de spiro-fluorofluorenes et de spiro- difluorofluorenes
CA000480349A CA1209048A (fr) 1982-04-15 1985-04-29 Composes de spiro-hydantoine pour inhiber l'aldose reductase

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA000425866A Division CA1200247A (fr) 1982-04-15 1983-04-14 Inhibition de l'activite de l'aldose reductase; compositions utilisees a cette fin et methode de preparation de spiro-fluorofluorenes et de spiro- difluorofluorenes

Publications (1)

Publication Number Publication Date
CA1209048A true CA1209048A (fr) 1986-08-05

Family

ID=27426365

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000480349A Expired CA1209048A (fr) 1982-04-15 1985-04-29 Composes de spiro-hydantoine pour inhiber l'aldose reductase

Country Status (1)

Country Link
CA (1) CA1209048A (fr)

Similar Documents

Publication Publication Date Title
US4436745A (en) Method of inhibiting aldose reductase activity
US4438272A (en) Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
FI62838B (fi) Foerfarande foer framstaellning av den nya farmaceutiskt anvaendbara hoegerroterande isomeren av en asymmetriskt spiro-hydantoinfoerening
DE2759927C2 (de) Spiro-hydantoin-Verbindungen
EP0014951A2 (fr) Dérivés hétérocycliques d'oxypropanolamine, procédé pour leur préparation et médicaments contenant ces composés
CH627753A5 (de) Verfahren zur herstellung von neuen sulfonylbenzimidazolen.
JPH02304080A (ja) 6H―ジベンゾ[b,d]ピラン―6―オン誘導体,その製法及び用途
CH623052A5 (fr)
EP0092385B1 (fr) Derivés d'hydantoine utilisés comme inhibiteurs de l'activité de l'aldose réductase, compositions correspondentes et procédé pour la préparation des composés spiro-fluorène
DD245870A5 (de) Verfahren zur herstellung von triazoyl-chinolin-derivate
CA1209048A (fr) Composes de spiro-hydantoine pour inhiber l'aldose reductase
US4540700A (en) Treatment of diabetic complications with certain spiro-imidazolidine-diones
DD232697A5 (de) Verfahren zur herstellung von benzimidazolen
CH642668A5 (de) 2,6-diaminonebularine, verfahren zu deren herstellung und sie enthaltende pharmazeutische praeparate.
DE1965711C3 (de) l^-Dihydro-133-triazin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2427207A1 (de) Verfahren zur herstellung von kondensierten pyrrolmercapto-verbindungen
CN117903049A (zh) 一种白藜芦醇衍生物及其制备方法和应用
DE3346640A1 (de) Neue imidazolderivate, deren herstellung und diese verbindungen enthaltende arzneimittel
US3682899A (en) 1-oxo - 3-benzal-thiochromanone derivatives and a process for the production of these compounds
US3420842A (en) Process for the preparation of 2-nitroimidazoles
JPH0455190B2 (fr)
CH630368A5 (en) Process for the preparation of 1-sulphonyl-5(6)-subst.-benzimidazoles.
PT87307B (pt) Processo para a preparacao de quinoxalil-imidazolidino-2,4-dionas substituidas e de composicoes farmaceuticas que as contem
US4464385A (en) Treatment of diabetic complications with hydantoins
DK169519B1 (da) Analogifremgangsmåde til fremstilling af spiro-(fluoren-9,4'-imidazolidin)-2',5'-dioner eller farmaceutisk acceptable salte deraf

Legal Events

Date Code Title Description
MKEX Expiry