CA1224461A - Antibiotic compound, a method for its preparation and compositions containing it - Google Patents

Antibiotic compound, a method for its preparation and compositions containing it

Info

Publication number
CA1224461A
CA1224461A CA000471563A CA471563A CA1224461A CA 1224461 A CA1224461 A CA 1224461A CA 000471563 A CA000471563 A CA 000471563A CA 471563 A CA471563 A CA 471563A CA 1224461 A CA1224461 A CA 1224461A
Authority
CA
Canada
Prior art keywords
erythromycin
stearate
acetyl
ester
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000471563A
Other languages
English (en)
French (fr)
Inventor
Martti Marvola
Esko Marttila
Pekka Kairisalo
Jaakko Uotila
Aino Pippuri
Erkki Honkanen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtyma Oy filed Critical Orion Yhtyma Oy
Application granted granted Critical
Publication of CA1224461A publication Critical patent/CA1224461A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring (AREA)
CA000471563A 1984-01-06 1985-01-04 Antibiotic compound, a method for its preparation and compositions containing it Expired CA1224461A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK5884A DK149776C (da) 1984-01-06 1984-01-06 Antibiotisk virksom erytromycinforbindelse og praeparat indeholdende forbindelsen
DK58/84 1984-01-06

Publications (1)

Publication Number Publication Date
CA1224461A true CA1224461A (en) 1987-07-21

Family

ID=8089251

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000471563A Expired CA1224461A (en) 1984-01-06 1985-01-04 Antibiotic compound, a method for its preparation and compositions containing it

Country Status (38)

Country Link
US (1) US4599326A (2)
JP (1) JPS60158197A (2)
KR (1) KR900006237B1 (2)
AT (1) AT386414B (2)
AU (1) AU565688B2 (2)
BE (1) BE901411A (2)
BG (1) BG43189A3 (2)
CA (1) CA1224461A (2)
CH (1) CH666275A5 (2)
CS (1) CS247191B2 (2)
CY (1) CY1462A (2)
DE (1) DE3500179A1 (2)
DK (1) DK149776C (2)
ES (1) ES8605818A1 (2)
FI (1) FI77249C (2)
FR (1) FR2557878B1 (2)
GB (1) GB2152502B (2)
HK (1) HK11590A (2)
HU (1) HU196221B (2)
IE (1) IE57967B1 (2)
IL (1) IL73885A (2)
IS (1) IS2968A7 (2)
IT (1) IT1184304B (2)
KE (1) KE3841A (2)
LU (1) LU85721A1 (2)
MA (1) MA20316A1 (2)
MX (1) MX156277A (2)
NL (1) NL8403979A (2)
NO (1) NO160263C (2)
NZ (1) NZ210606A (2)
PH (1) PH22471A (2)
PL (1) PL144349B1 (2)
PT (1) PT79777B (2)
RO (1) RO91262B (2)
SE (1) SE461854B (2)
SU (1) SU1410866A3 (2)
YU (1) YU44485B (2)
ZA (1) ZA8410143B (2)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874614A (en) * 1985-03-25 1989-10-17 Abbott Laboratories Pharmaceutical tableting method
US4863741A (en) * 1985-03-25 1989-09-05 Abbott Laboratories Tablet composition for drug combinations
JP3382159B2 (ja) * 1998-08-05 2003-03-04 株式会社東芝 情報記録媒体とその再生方法及び記録方法
US8840928B2 (en) 2002-07-05 2014-09-23 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
CA2491572C (en) * 2002-07-05 2010-03-23 Collegium Pharmaceutical, Inc. Abuse-deterrent pharmaceutical compositions of opiods and other drugs
US10004729B2 (en) 2002-07-05 2018-06-26 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
EP1677758A1 (en) * 2003-10-31 2006-07-12 ALZA Corporation Compositions and dosage forms for enhanced absorption of 3-amino-n-butyl-phosphinic acid
HUE037643T2 (hu) 2004-06-12 2018-09-28 Collegium Pharmaceutical Inc Visszaélésre nem alkalmas gyógyszerkészítmények
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
WO2006025882A2 (en) 2004-08-25 2006-03-09 The Uab Research Foundation Absorption enhancers for drug administration
EP2505189B1 (en) 2006-06-23 2018-08-08 Aegis Therapeutics, LLC Stabilizing alkylglycoside compositions and method thereof
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
WO2012158962A2 (en) 2011-05-18 2012-11-22 Eumederis Pharmaceuticals, Inc. Improved peptide pharmaceuticals
AU2013347975B2 (en) 2012-11-20 2018-07-26 Mederis Diabetes, Llc Improved peptide pharmaceuticals for insulin resistance
CA2891929C (en) 2012-11-20 2022-07-19 Eumederis Pharmaceuticals, Inc. Improved peptide pharmaceuticals
WO2014140699A1 (en) * 2013-03-13 2014-09-18 Calyx Chemicals And Pharmaceuticals Ltd A novel process of liberation of erythromycin and preparation of its salts
HUE066179T2 (hu) 2014-05-28 2024-07-28 Mederis Diabetes Llc Javított peptidek inzulinrezisztencia ellen
WO2017222575A1 (en) 2016-06-23 2017-12-28 Collegium Pharmaceutical, Inc. Process of making more stable abuse-deterrent oral formulations
CN111315400A (zh) 2017-05-19 2020-06-19 卢内拉生物技术有限公司 Antimitoscin：用于根除癌症干细胞的线粒体生物发生的靶向抑制剂
EP3717015A4 (en) 2017-12-01 2021-07-28 Lunella Biotech, Inc. REPURPOSCINS: TARGET MITOCHONDRIAL BIOGENESIS INHIBITORS TO ERADICATE CARCINOUS STEM CELLS
WO2019157099A1 (en) 2018-02-06 2019-08-15 Aegis Therapeutics, Llc Intranasal epinephrine formulations and methods for the treatment of disease
IL276485B2 (en) 2018-02-06 2024-12-01 Aegis Therapeutics Llc Intranasal epinephrine formulations and methods for the treatment of disease
CA3123838A1 (en) * 2018-12-17 2020-06-25 Lunella Biotech, Inc. Triple combination therapies for targeting mitochondria and killing cancer stem cells
CN113453690A (zh) * 2018-12-17 2021-09-28 卢内拉生物技术有限公司 用于抗衰老的三联疗法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1011117B (de) * 1953-11-16 1957-06-27 Abbott Lab Verfahren zur Herstellung von reinen stabilen Erythromycin-Saeure-Additionssalzen
FR1179208A (fr) * 1953-11-16 1959-05-21 Abbott Lab Procédé de préparation de sels d'érythromycine
GB834397A (en) * 1958-07-29 1960-05-04 Lilly Co Eli Therapeutic compositions comprising erythromycin esters
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives
FR2473525A1 (fr) * 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
FI850023L (fi) 1985-07-07
SU1410866A3 (ru) 1988-07-15
AT386414B (de) 1988-08-25
GB2152502B (en) 1987-10-07
IE850022L (en) 1985-07-06
ES8605818A1 (es) 1986-04-01
AU3705984A (en) 1985-07-11
DE3500179A1 (de) 1985-07-18
LU85721A1 (fr) 1985-07-24
PL144349B1 (en) 1988-05-31
GB8432368D0 (en) 1985-02-06
HUT37628A (en) 1986-01-23
HK11590A (en) 1990-02-23
HU196221B (en) 1988-10-28
RO91262A (ro) 1987-06-30
YU2085A (en) 1987-12-31
JPS60158197A (ja) 1985-08-19
RO91262B (ro) 1987-07-01
CS247191B2 (en) 1986-12-18
ZA8410143B (en) 1985-08-28
IE57967B1 (en) 1993-06-02
IL73885A (en) 1988-10-31
NZ210606A (en) 1987-08-31
GB2152502A (en) 1985-08-07
PL251457A1 (en) 1985-11-05
PT79777A (en) 1985-01-01
NO160263C (no) 1989-03-29
BG43189A3 (en) 1988-04-15
KR850005452A (ko) 1985-08-26
DE3500179C2 (2) 1989-08-24
US4599326A (en) 1986-07-08
CY1462A (en) 1989-07-21
IL73885A0 (en) 1985-03-31
PH22471A (en) 1988-09-12
IT1184304B (it) 1987-10-28
NO850007L (no) 1985-07-08
KR900006237B1 (ko) 1990-08-27
BE901411A (fr) 1985-04-16
IS2968A7 (is) 1985-04-03
FI77249C (fi) 1989-02-10
FR2557878A1 (fr) 1985-07-12
SE8406671L (sv) 1985-07-07
ES539349A0 (es) 1986-04-01
ATA985A (de) 1988-01-15
JPH029040B2 (2) 1990-02-28
FI850023A0 (fi) 1985-01-03
DK5884A (da) 1985-07-07
YU44485B (en) 1990-08-31
MA20316A1 (fr) 1985-10-01
SE461854B (sv) 1990-04-02
NL8403979A (nl) 1985-08-01
FR2557878B1 (fr) 1988-01-15
DK149776C (da) 1987-04-21
CH666275A5 (de) 1988-07-15
NO160263B (no) 1988-12-19
IT8519012A0 (it) 1985-01-04
DK5884D0 (da) 1984-01-06
AU565688B2 (en) 1987-09-24
FI77249B (fi) 1988-10-31
PT79777B (en) 1986-10-21
DK149776B (da) 1986-09-29
MX156277A (es) 1988-08-04
KE3841A (en) 1989-04-07
SE8406671D0 (sv) 1984-12-28

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