CA1250832A - PREPARATION OF 2-OXINDOLE-1-CARBOXAMIDES; INTERMEDIATE PRODUCTS - Google Patents

PREPARATION OF 2-OXINDOLE-1-CARBOXAMIDES; INTERMEDIATE PRODUCTS

Info

Publication number
CA1250832A
CA1250832A CA000476599A CA476599A CA1250832A CA 1250832 A CA1250832 A CA 1250832A CA 000476599 A CA000476599 A CA 000476599A CA 476599 A CA476599 A CA 476599A CA 1250832 A CA1250832 A CA 1250832A
Authority
CA
Canada
Prior art keywords
oxindole
carboxamides
making
intermediates therefor
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000476599A
Other languages
English (en)
French (fr)
Other versions
CA1253490C (2
Inventor
Thomas C Crawford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Priority to CA000566447A priority Critical patent/CA1253490A/en
Publication of CA1250832A publication Critical patent/CA1250832A/en
Application granted granted Critical
Publication of CA1253490C publication Critical patent/CA1253490C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000476599A 1984-03-19 1985-03-15 PREPARATION OF 2-OXINDOLE-1-CARBOXAMIDES; INTERMEDIATE PRODUCTS Expired CA1250832A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000566447A CA1253490A (en) 1984-03-19 1988-05-10 Process for making 2-oxindole-1-carboxamides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59066784A 1984-03-19 1984-03-19
US68488984A 1984-12-21 1984-12-21

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000566447A Division CA1253490A (en) 1984-03-19 1988-05-10 Process for making 2-oxindole-1-carboxamides

Publications (2)

Publication Number Publication Date
CA1250832A true CA1250832A (en) 1989-03-07
CA1253490C CA1253490C (2) 1989-05-02

Family

ID=27080914

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000476599A Expired CA1250832A (en) 1984-03-19 1985-03-15 PREPARATION OF 2-OXINDOLE-1-CARBOXAMIDES; INTERMEDIATE PRODUCTS

Country Status (29)

Country Link
EP (1) EP0155828B1 (2)
JP (1) JPH03178963A (2)
KR (1) KR860001874B1 (2)
AR (1) AR247885A1 (2)
AU (1) AU552119B2 (2)
BG (1) BG44203A3 (2)
CA (1) CA1250832A (2)
CS (1) CS250680B2 (2)
CY (1) CY1667A (2)
DE (1) DE3579716D1 (2)
DK (2) DK163662C (2)
EG (1) EG17274A (2)
ES (1) ES8603409A1 (2)
FI (1) FI85265C (2)
GR (1) GR850669B (2)
HK (1) HK75992A (2)
HU (1) HU194825B (2)
IE (1) IE57741B1 (2)
IL (1) IL74630A (2)
MA (1) MA20379A1 (2)
NO (1) NO168639C (2)
NZ (1) NZ211487A (2)
OA (1) OA07967A (2)
PH (1) PH20843A (2)
PL (1) PL145873B1 (2)
PT (1) PT80116B (2)
RO (1) RO90953B (2)
YU (1) YU43869B (2)
ZW (1) ZW4885A1 (2)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0276500B1 (en) * 1984-02-07 1991-05-15 Pfizer Inc. 2-oxindole intermediates
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
DE3621761A1 (de) * 1986-06-28 1988-01-07 Bayer Ag Indolylpropionsaeuren
RO105052B1 (en) * 1987-02-02 1994-12-01 Pfizer Producing process for the crystalline sodium salt, anhydre, of 5-chlorine-3-(2-tenoil)-2-oxindol-1-carboxamide
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
US4952703A (en) * 1989-05-25 1990-08-28 Pfizer Inc. Intermediates for making 2-oxindole-1-carboxamides
HUP9600855A3 (en) * 1996-04-03 1998-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing tenidap
WO2002070478A1 (en) 2001-03-06 2002-09-12 Astrazeneca Ab Indolone derivatives having vascular-damaging activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767653A (en) * 1971-06-28 1973-10-23 Squibb & Sons Inc Thiazines

Also Published As

Publication number Publication date
NO168639B (no) 1991-12-09
KR850006174A (ko) 1985-10-02
FI85265C (fi) 1992-03-25
DK121485A (da) 1985-09-20
DK163662C (da) 1992-08-31
PL145873B1 (en) 1988-11-30
PT80116A (en) 1985-04-01
HUT37397A (en) 1985-12-28
JPH0525875B2 (2) 1993-04-14
PL252433A1 (en) 1985-12-03
YU42885A (en) 1987-10-31
FI85265B (fi) 1991-12-13
FI851068L (fi) 1985-09-20
DK64591D0 (da) 1991-04-11
DK121485D0 (da) 1985-03-18
EP0155828A3 (en) 1986-02-05
OA07967A (fr) 1987-01-31
DK64591A (da) 1991-04-11
IL74630A0 (en) 1985-06-30
DE3579716D1 (de) 1990-10-25
KR860001874B1 (ko) 1986-10-24
AR247885A1 (es) 1995-04-28
AU4005885A (en) 1985-09-26
PT80116B (pt) 1987-10-20
CA1253490C (2) 1989-05-02
MA20379A1 (fr) 1985-10-01
NO168639C (no) 1992-03-18
RO90953B (ro) 1987-02-28
CY1667A (en) 1993-05-14
BG44203A3 (en) 1988-10-14
DK165179C (da) 1993-03-01
DK163662B (da) 1992-03-23
IE850683L (en) 1985-09-19
YU43869B (en) 1989-12-31
FI851068A0 (fi) 1985-03-18
EP0155828B1 (en) 1990-09-19
HU194825B (en) 1988-03-28
DK165179B (da) 1992-10-19
EP0155828A2 (en) 1985-09-25
EG17274A (en) 1989-06-30
AU552119B2 (en) 1986-05-22
NZ211487A (en) 1988-11-29
JPH03178963A (ja) 1991-08-02
IL74630A (en) 1988-04-29
NO851059L (no) 1985-09-20
CS250680B2 (en) 1987-05-14
ES541373A0 (es) 1985-12-16
PH20843A (en) 1987-05-08
ES8603409A1 (es) 1985-12-16
RO90953A (ro) 1987-02-27
GR850669B (2) 1985-07-25
IE57741B1 (en) 1993-03-24
ZW4885A1 (en) 1985-06-26
HK75992A (en) 1992-10-09

Similar Documents

Publication Publication Date Title
AU3619884A (en) Non-expansive,rapid setting cement
ES8800272A1 (es) Un procedimiento para la preparacion de polipeptidos.
IL93999A0 (en) Naphthalenecarboxylic acid intermediates for the production of podophyllotoxin and related compounds and their preparation
ES482414A1 (es) Procedimiento para la preparacion del acido 4-aminohex-5- anoico o una sal del mismo.
CA1250832A (en) PREPARATION OF 2-OXINDOLE-1-CARBOXAMIDES; INTERMEDIATE PRODUCTS
DE3562021D1 (en) Process for the obtention of methane by fermentation of algae
ZA851808B (en) Production of alloy steels using chemically preparated v2 o3 as a vanadium additive
GR3019276T3 (en) Process for making 2-oxindole-1-carboxamides
ES478706A1 (es) Un metodo para producir un compuesto desmetilmaitansinoide.
ES2023560A6 (es) Procedimiento para la produccion de hidrato de cefradina y solvato de cefradina y dimetilformamida.
DE3460902D1 (en) Process for the production of methane by anaerobic fermentation
MY101826A (en) Process for making 2-oxindole-1-carboxamides and intermediates therefor.
DE3574018D1 (en) Process for the preparation of n1-methyl-10alpha-methoxylumilysergol and esters thereof, and intermediates for their preparation
JPS5599194A (en) Production of aldonic acid by enzyme method
IE44046L (en) Cyclopropanes
ES469645A1 (es) Procedimiento para la preparacion de 3-bromoftalida.
EP0146929A3 (en) Microorganism of the genus serratia containing a hybrid plasmid and process for preparing the same
ES8704895A1 (es) Un metodo para preparar 1-aminoalquilamino-4-ariloxipiperidinas sustituidas
PT80996A (en) Process for preparing 6-fluoro-chroman-4-carboxylic acid derivatives
GB1515640A (en) Process for the synthesis of 3-benzoylhydratropic acid
ES8303331A1 (es) Un procedimiento para preparar un pirrol-2-acetato de alquilo inferior sustituido en las posiciones 1 y 4.
AU518874B2 (en) Conversion of molten iron to molten steel
GB2084566B (en) Production of l-arginine by fermentation
JPS5256195A (en) Process for polyurethane
ZA795688B (en) Direct method for production of high-grade,high purity ferromanganese

Legal Events

Date Code Title Description
MKEX Expiry