ES8303331A1 - Un procedimiento para preparar un pirrol-2-acetato de alquilo inferior sustituido en las posiciones 1 y 4. - Google Patents
Un procedimiento para preparar un pirrol-2-acetato de alquilo inferior sustituido en las posiciones 1 y 4.Info
- Publication number
- ES8303331A1 ES8303331A1 ES506775A ES506775A ES8303331A1 ES 8303331 A1 ES8303331 A1 ES 8303331A1 ES 506775 A ES506775 A ES 506775A ES 506775 A ES506775 A ES 506775A ES 8303331 A1 ES8303331 A1 ES 8303331A1
- Authority
- ES
- Spain
- Prior art keywords
- substituted pyrroles
- producing substituted
- pyrrole
- recovered
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003233 pyrroles Chemical class 0.000 title 1
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- -1 alkyl pyrrole-2-acetic acid Chemical compound 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UN PIRROL-2-ACETATO DE ALQUILO INFERIOR SUSTITUIDO EN LAS POSICIONES 1 Y 4, QUE TIENE LA FORMULA GENERAL (I), EN DONDE R4 Y R5 SE SELECCIONAN CADA UNO DE ELLOS INDEPENDIENTEMENTE DE GRUPOS DE ALQUILO INFERIOR. CONSISTE EN PONER EN CONTACTO UN COMPUESTO REACTIVO DE PIRROL, DE FORMULA GENERAL (II), EN DONDE R4 Y R5 TIENEN LOS SIGNIFICADOS YA INDICADOS; Y R7 Y R8 SE SELECCIONAN CADA UNO DE ELLOS INDEPENDIENTEMENTE ENTRE RADICALES -COOH, -COO, -ALQUILO INFERIOR, Y -COOM, DONDE M SIGNIFICA SODIO O POTASIO, CON UNA MEZCLA DE ACIDO MINERAL FUERTE, UN ALCANOL INFERIOR Y AGUA. DE APLICACION EN FARMACIA POR SU ACTIVIDAD ANTINFLAMATORIA. *FORMULA*
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20305280A | 1980-11-03 | 1980-11-03 | |
| US20995080A | 1980-11-24 | 1980-11-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8303331A1 true ES8303331A1 (es) | 1983-02-01 |
| ES506775A0 ES506775A0 (es) | 1983-02-01 |
Family
ID=26898265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506775A Granted ES506775A0 (es) | 1980-11-03 | 1981-11-02 | Un procedimiento para preparar un pirrol-2-acetato de alquilo inferior sustituido en las posiciones 1 y 4. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0051442A1 (es) |
| JP (1) | JPS57501849A (es) |
| CA (1) | CA1161851A (es) |
| DK (1) | DK297582A (es) |
| ES (1) | ES506775A0 (es) |
| NO (1) | NO822322L (es) |
| WO (1) | WO1982001552A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4374997A (en) * | 1981-06-04 | 1983-02-22 | Merck & Co., Inc. | Process for the preparation of zomepirac and related compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6512721A (es) * | 1964-03-25 | 1966-04-13 | ||
| US3952012A (en) * | 1970-01-26 | 1976-04-20 | Mcneil Laboratories, Incorporated | Aroyl-substituted pyrroles |
| US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
-
1981
- 1981-10-22 CA CA000388497A patent/CA1161851A/en not_active Expired
- 1981-10-27 JP JP56503658A patent/JPS57501849A/ja active Pending
- 1981-10-27 WO PCT/US1981/001443 patent/WO1982001552A1/en not_active Ceased
- 1981-10-28 EP EP81305101A patent/EP0051442A1/en not_active Withdrawn
- 1981-11-02 ES ES506775A patent/ES506775A0/es active Granted
-
1982
- 1982-07-02 DK DK297582A patent/DK297582A/da not_active Application Discontinuation
- 1982-07-02 NO NO822322A patent/NO822322L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1161851A (en) | 1984-02-07 |
| DK297582A (da) | 1982-07-02 |
| ES506775A0 (es) | 1983-02-01 |
| WO1982001552A1 (en) | 1982-05-13 |
| NO822322L (no) | 1982-07-02 |
| JPS57501849A (es) | 1982-10-14 |
| EP0051442A1 (en) | 1982-05-12 |
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