CA1257331A - Sonde a electrodes selectives d'ions - Google Patents
Sonde a electrodes selectives d'ionsInfo
- Publication number
- CA1257331A CA1257331A CA000512665A CA512665A CA1257331A CA 1257331 A CA1257331 A CA 1257331A CA 000512665 A CA000512665 A CA 000512665A CA 512665 A CA512665 A CA 512665A CA 1257331 A CA1257331 A CA 1257331A
- Authority
- CA
- Canada
- Prior art keywords
- ion
- selective
- sensor
- sample
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 150000002148 esters Chemical class 0.000 description 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
- NIPNPMUJWJSXTE-UHFFFAOYSA-N ethyl 3-amino-4-octadecoxybenzoate Chemical compound CCCCCCCCCCCCCCCCCCOC1=CC=C(C(=O)OCC)C=C1N NIPNPMUJWJSXTE-UHFFFAOYSA-N 0.000 description 1
- FBHJNBWUGONVNS-UHFFFAOYSA-N ethyl 4-hydroxy-3-nitrobenzoate Chemical compound CCOC(=O)C1=CC=C(O)C([N+]([O-])=O)=C1 FBHJNBWUGONVNS-UHFFFAOYSA-N 0.000 description 1
- OAYLNYINCPYISS-UHFFFAOYSA-N ethyl acetate;hexane Chemical compound CCCCCC.CCOC(C)=O OAYLNYINCPYISS-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 239000005038 ethylene vinyl acetate Substances 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 229940068517 fruit extracts Drugs 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 239000003517 fume Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000005661 hydrophobic surface Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 description 1
- 229940006461 iodide ion Drugs 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 235000019626 lipase activity Nutrition 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 239000011654 magnesium acetate Substances 0.000 description 1
- 235000011285 magnesium acetate Nutrition 0.000 description 1
- UEGPKNKPLBYCNK-UHFFFAOYSA-L magnesium acetate Chemical compound [Mg+2].CC([O-])=O.CC([O-])=O UEGPKNKPLBYCNK-UHFFFAOYSA-L 0.000 description 1
- 229940069446 magnesium acetate Drugs 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 238000003760 magnetic stirring Methods 0.000 description 1
- CUONGYYJJVDODC-UHFFFAOYSA-N malononitrile Chemical compound N#CCC#N CUONGYYJJVDODC-UHFFFAOYSA-N 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229910001507 metal halide Inorganic materials 0.000 description 1
- 150000005309 metal halides Chemical class 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229960005358 monensin Drugs 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229910000069 nitrogen hydride Inorganic materials 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 229950009506 penicillinase Drugs 0.000 description 1
- XNLICIUVMPYHGG-UHFFFAOYSA-N pentan-2-one Chemical compound CCCC(C)=O XNLICIUVMPYHGG-UHFFFAOYSA-N 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 150000003016 phosphoric acids Chemical class 0.000 description 1
- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
- 102000020233 phosphotransferase Human genes 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 229940075930 picrate Drugs 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 description 1
- 108010020002 platelet endothelial cell activated protease Proteins 0.000 description 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 235000013324 preserved food Nutrition 0.000 description 1
- SCUZVMOVTVSBLE-UHFFFAOYSA-N prop-2-enenitrile;styrene Chemical compound C=CC#N.C=CC1=CC=CC=C1 SCUZVMOVTVSBLE-UHFFFAOYSA-N 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- BDJXVNRFAQSMAA-UHFFFAOYSA-N quinhydrone Chemical compound OC1=CC=C(O)C=C1.O=C1C=CC(=O)C=C1 BDJXVNRFAQSMAA-UHFFFAOYSA-N 0.000 description 1
- 229940052881 quinhydrone Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000021067 refined food Nutrition 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000004627 regenerated cellulose Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical class OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 description 1
- RDZTWEVXRGYCFV-UHFFFAOYSA-M sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate Chemical compound [Na+].OCCN1CCN(CCS([O-])(=O)=O)CC1 RDZTWEVXRGYCFV-UHFFFAOYSA-M 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000010288 sodium nitrite Nutrition 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- XOIQMTLWECTKJL-FBZUZRIGSA-M sodium;(2s,3r,4s)-4-[(2s,5r,7s,8r,9s)-2-[(2r,5s)-5-ethyl-5-[(2r,3s,5r)-5-[(2s,3s,5r,6r)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoate Chemical compound [Na+].C([C@@](O1)(C)[C@H]2CC[C@@](O2)(CC)[C@H]2[C@H](C[C@@H](O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C[C@@]21C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C([O-])=O)O2 XOIQMTLWECTKJL-FBZUZRIGSA-M 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 229920000638 styrene acrylonitrile Polymers 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 230000002277 temperature effect Effects 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- WTLBZVNBAKMVDP-UHFFFAOYSA-N tris(2-butoxyethyl) phosphate Chemical compound CCCCOCCOP(=O)(OCCOCCCC)OCCOCCCC WTLBZVNBAKMVDP-UHFFFAOYSA-N 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/492—Determining multiple analytes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75052585A | 1985-06-27 | 1985-06-27 | |
| US750,525 | 1985-06-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1257331A true CA1257331A (fr) | 1989-07-11 |
Family
ID=25018222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000512665A Expired CA1257331A (fr) | 1985-06-27 | 1986-06-27 | Sonde a electrodes selectives d'ions |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0230449A1 (fr) |
| JP (1) | JPS63500539A (fr) |
| AU (1) | AU602868B2 (fr) |
| CA (1) | CA1257331A (fr) |
| DK (1) | DK98987A (fr) |
| IL (1) | IL79230A0 (fr) |
| WO (1) | WO1987000286A1 (fr) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988000708A1 (fr) * | 1986-07-21 | 1988-01-28 | Ilex Corporation | Analyseur utilise en chimie clinique |
| US4889613A (en) * | 1987-09-11 | 1989-12-26 | Beckman Instruments, Inc. | Analytical apparatus, electrode and sample container for use therewith |
| CA1307825C (fr) * | 1987-12-09 | 1992-09-22 | Michael H. Burnam | Methode et appareil pour l'analyse du sang par dosage unique |
| DK409188D0 (da) * | 1988-07-21 | 1988-07-21 | Radiometer As | Fremgangsmaade til maaling af en karakteristik i et fluidum |
| US5235526A (en) * | 1990-11-27 | 1993-08-10 | Solomat Limited | Multi-probed sonde including microprocessor |
| WO1995025953A1 (fr) * | 1994-03-22 | 1995-09-28 | Hans Opl | Capteur de controle de l'activite ionique dans les liquides biologiques |
| JP3595907B2 (ja) * | 1996-06-21 | 2004-12-02 | デイド、ベーリング、インコーポレイテッド | イオン選択性電極製造のための組成物および方法 |
| WO1998019159A1 (fr) | 1996-10-30 | 1998-05-07 | Mercury Diagnostics, Inc. | Systeme d'essai synchronise de l'analysat |
| DE19747875A1 (de) * | 1997-10-20 | 1999-05-06 | Meinhard Prof Dr Knoll | Verfahren zum Messen veränderlicher Größen und Vorrichtung zum Durchführen des Verfahrens |
| DE69839771D1 (de) * | 1998-10-09 | 2008-09-04 | Asulab Sa | Einfach handzuhabender streifenförmiger elektrochemischer Sensor |
| US7810380B2 (en) | 2003-03-25 | 2010-10-12 | Tearlab Research, Inc. | Systems and methods for collecting tear film and measuring tear film osmolarity |
| US7905134B2 (en) | 2002-08-06 | 2011-03-15 | The Regents Of The University Of California | Biomarker normalization |
| JP4988581B2 (ja) | 2004-10-12 | 2012-08-01 | バイエル・ヘルスケア・エルエルシー | 拡散隔膜レイヤーにおける濃度測定 |
| PT2142905E (pt) * | 2007-04-16 | 2013-04-23 | Univ California | Normalização de marcador biológico |
| US9952174B2 (en) | 2014-04-18 | 2018-04-24 | Siemens Healthcare Diagnostics Inc. | Magnesium sensing membrane for potentiometric ion selective electrode for measuring ionized magnesium and methods of production and use thereof |
| JP6749848B2 (ja) | 2014-06-12 | 2020-09-02 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | 電位差滴定マグネシウムイオン選択性電極センサのための試薬並びにその製造方法及び使用方法 |
| BR112017005121A2 (pt) | 2014-09-23 | 2018-07-31 | Tearlab Res Inc | sistemas e métodos para integração de coleta de lágrima microfluídica e análise de fluxo lateral de analitos de interesse. |
| US9883827B2 (en) | 2015-03-09 | 2018-02-06 | CoreSyte, Inc. | System and method for measuring biological fluid biomarkers |
| US9645133B2 (en) | 2015-03-09 | 2017-05-09 | CoreSyte, Inc. | Method for manufacturing a biological fluid sensor |
| US9636061B2 (en) | 2015-03-09 | 2017-05-02 | CoreSyte, Inc. | System and method for measuring biological fluid biomarkers |
| US11389087B2 (en) | 2015-03-09 | 2022-07-19 | CoreSyte, Inc. | Device for measuring biological fluids |
| US10327676B2 (en) | 2015-03-09 | 2019-06-25 | CoreSyte, Inc. | Device for measuring biological fluids |
| US10561405B2 (en) | 2015-03-09 | 2020-02-18 | CoreSyte, Inc. | Method for manufacturing a biological fluid sensor |
| US9579024B2 (en) | 2015-03-09 | 2017-02-28 | CoreSyte, Inc. | System and method for measuring biological fluid biomarkers |
| US11883011B2 (en) | 2015-03-09 | 2024-01-30 | CoreSyte, Inc. | Method for manufacturing a biological fluid sensor |
| US11998319B2 (en) | 2015-03-09 | 2024-06-04 | CoreSyte, Inc. | Device for measuring biological fluids |
| US9622725B2 (en) | 2015-03-09 | 2017-04-18 | CoreSyte, Inc. | Method for manufacturing a biological fluid sensor |
| WO2016144529A1 (fr) * | 2015-03-09 | 2016-09-15 | CoreSyte, Inc. | Procédés de fabrication de dispositifs de type capteurs de fluides biologiques et dispositifs, systèmes, et procédés de mesure de fluides biologiques |
| US10925499B2 (en) | 2017-03-02 | 2021-02-23 | SP Global, Inc. | System and method for using integrated sensor arrays to measure and analyze multiple biosignatures in real time |
| EP3388825A1 (fr) * | 2017-04-12 | 2018-10-17 | Medizinische Universität Innsbruck | Capteur potentiometrique pour la détermination quantitative de la concentration de sodium et la concentration de créatinine |
| US11016074B2 (en) * | 2018-03-29 | 2021-05-25 | Ecowater Systems, Llc | Apparatus for measuring water hardness using ion selective electrode |
| EP4016068B1 (fr) * | 2020-12-21 | 2025-03-05 | F. Hoffmann-La Roche AG | Ensemble capteurs |
| CN121410077B (zh) * | 2025-12-30 | 2026-04-07 | 四川省科源工程技术测试中心有限责任公司 | 基于电化学控制变量分析法的土壤成分测定装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4053381A (en) * | 1976-05-19 | 1977-10-11 | Eastman Kodak Company | Device for determining ionic activity of components of liquid drops |
| US4214968A (en) * | 1978-04-05 | 1980-07-29 | Eastman Kodak Company | Ion-selective electrode |
| US4225410A (en) * | 1978-12-04 | 1980-09-30 | Technicon Instruments Corporation | Integrated array of electrochemical sensors |
| US4273639A (en) * | 1979-06-20 | 1981-06-16 | Eastman Kodak Company | Capillary bridge in apparatus for determining ionic activity |
| US4413407A (en) * | 1980-03-10 | 1983-11-08 | Eastman Kodak Company | Method for forming an electrode-containing device with capillary transport between electrodes |
| JPS58140635A (ja) * | 1982-02-16 | 1983-08-20 | Fuji Photo Film Co Ltd | 液体移送分配装置およびイオン活量測定器具 |
-
1986
- 1986-06-25 JP JP61503624A patent/JPS63500539A/ja active Pending
- 1986-06-25 AU AU61244/86A patent/AU602868B2/en not_active Expired - Fee Related
- 1986-06-25 IL IL79230A patent/IL79230A0/xx unknown
- 1986-06-25 EP EP86904582A patent/EP0230449A1/fr not_active Withdrawn
- 1986-06-25 WO PCT/US1986/001370 patent/WO1987000286A1/fr not_active Ceased
- 1986-06-27 CA CA000512665A patent/CA1257331A/fr not_active Expired
-
1987
- 1987-02-26 DK DK098987A patent/DK98987A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU602868B2 (en) | 1990-11-01 |
| DK98987D0 (da) | 1987-02-26 |
| JPS63500539A (ja) | 1988-02-25 |
| IL79230A0 (en) | 1986-09-30 |
| EP0230449A1 (fr) | 1987-08-05 |
| DK98987A (da) | 1987-04-27 |
| AU6124486A (en) | 1987-01-30 |
| WO1987000286A1 (fr) | 1987-01-15 |
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Legal Events
| Date | Code | Title | Description |
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| MKEX | Expiry |