CA1268188A - Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol - Google Patents

Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol

Info

Publication number: CA1268188A
Authority: CA; Canada
Prior art keywords: tocopherol; optically active; synthesis; phytol; synthesized
Prior art date: 1981-02-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA000480668A

Other languages

English (en)

Inventor

Kimio Hamamura

Kozo Akasaka

Youji Yamagishi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eisai Co Ltd

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-02-19

Filing date

1985-05-02

Publication date

1990-04-24

1981-02-19 Priority claimed from JP56022212A external-priority patent/JPS57136582A/ja

1985-05-02 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

1985-05-02 Priority to CA000480668A priority Critical patent/CA1268188A/fr

1990-04-24 Application granted granted Critical

1990-04-24 Publication of CA1268188A publication Critical patent/CA1268188A/fr

2007-04-24 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title abstract 3
230000015572 biosynthetic process Effects 0.000 title 1
GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
229960001295 tocopherol Drugs 0.000 title 1
229930003799 tocopherol Natural products 0.000 title 1
235000010384 tocopherol Nutrition 0.000 title 1
239000011732 tocopherol Substances 0.000 title 1
239000001707 (E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol Substances 0.000 abstract 1
BLUHKGOSFDHHGX-UHFFFAOYSA-N Phytol Natural products CC(C)CCCC(C)CCCC(C)CCCC(C)C=CO BLUHKGOSFDHHGX-UHFFFAOYSA-N 0.000 abstract 1
HNZBNQYXWOLKBA-UHFFFAOYSA-N Tetrahydrofarnesol Natural products CC(C)CCCC(C)CCCC(C)=CCO HNZBNQYXWOLKBA-UHFFFAOYSA-N 0.000 abstract 1
BOTWFXYSPFMFNR-OALUTQOASA-N all-rac-phytol Natural products CC(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)=CCO BOTWFXYSPFMFNR-OALUTQOASA-N 0.000 abstract 1
229940087168 alpha tocopherol Drugs 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
BOTWFXYSPFMFNR-PYDDKJGSSA-N phytol Chemical compound CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC\C(C)=C\CO BOTWFXYSPFMFNR-PYDDKJGSSA-N 0.000 abstract 1
239000007858 starting material Substances 0.000 abstract 1
229960000984 tocofersolan Drugs 0.000 abstract 1
239000002076 α-tocopherol Substances 0.000 abstract 1
235000004835 α-tocopherol Nutrition 0.000 abstract 1

Landscapes

Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrane Compounds (AREA)

CA000480668A 1981-02-19 1985-05-02 Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol Expired - Fee Related CA1268188A (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA000480668A CA1268188A (fr)	1981-02-19	1985-05-02	Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP56022212A JPS57136582A (en)	1981-02-19	1981-02-19	Preparation of optically active alpha-tocopherol
CA 396522 CA1268188C (fr)	1981-02-19	1982-02-18	Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol
CA000480668A CA1268188A (fr)	1981-02-19	1985-05-02	Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
CA 396522 Division CA1268188C (fr)	1981-02-19	1982-02-18	Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol

Publications (1)

Publication Number	Publication Date
CA1268188A true CA1268188A (fr)	1990-04-24

Family

ID=25669579

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA000480668A Expired - Fee Related CA1268188A (fr)	1981-02-19	1985-05-02	Produits intermediaires pour la synthese d'isomeres optiquement actifs du d-o-tocopherol
CA000480669A Expired CA1239647A (fr)	1981-02-19	1985-05-02	INTERMEDIAIRE POUR LA SYNTHESE DE D-.alpha.-TOCOPHEROL

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CA000480669A Expired CA1239647A (fr)	1981-02-19	1985-05-02	INTERMEDIAIRE POUR LA SYNTHESE DE D-.alpha.-TOCOPHEROL

Country Status (1)

Country	Link
CA (2)	CA1268188A (fr)

1985
- 1985-05-02 CA CA000480668A patent/CA1268188A/fr not_active Expired - Fee Related
- 1985-05-02 CA CA000480669A patent/CA1239647A/fr not_active Expired

Also Published As

Publication number	Publication date
CA1239647A (fr)	1988-07-26

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Legal Events

Date	Code	Title	Description
1992-10-26	MKLA	Lapsed