CA1279005C - Porous hydrophobic membrane and method of using same - Google Patents

Porous hydrophobic membrane and method of using same

Info

Publication number: CA1279005C
Authority: CA; Canada
Prior art keywords: membrane; capsule; reaction; liquid; immunoassay
Prior art date: 1985-04-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CA000506891A

Other languages

English (en)

French (fr)

Inventor

Paul C. Harris

Linda J. Stone

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Beckman Coulter Inc

Original Assignee

Beckman Instruments Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-18

Filing date

1986-04-17

Publication date

1991-01-15

1986-04-17 Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc

1991-01-15 Application granted granted Critical

1991-01-15 Publication of CA1279005C publication Critical patent/CA1279005C/en

2008-01-15 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000012528 membrane Substances 0.000 title claims abstract description 44
230000002209 hydrophobic effect Effects 0.000 title claims abstract description 31
238000000034 method Methods 0.000 title claims abstract description 21
239000002775 capsule Substances 0.000 claims abstract description 98
238000006243 chemical reaction Methods 0.000 claims abstract description 49
238000003018 immunoassay Methods 0.000 claims abstract description 31
239000007788 liquid Substances 0.000 claims abstract description 31
239000000758 substrate Substances 0.000 claims abstract description 30
239000012530 fluid Substances 0.000 claims description 20
239000007787 solid Substances 0.000 claims description 16
239000000463 material Substances 0.000 claims description 9
239000013610 patient sample Substances 0.000 claims description 9
239000000126 substance Substances 0.000 claims description 9
239000011148 porous material Substances 0.000 claims description 7
239000011159 matrix material Substances 0.000 claims description 2
BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 claims description 2
238000003260 vortexing Methods 0.000 claims description 2
230000000717 retained effect Effects 0.000 claims 2
238000003825 pressing Methods 0.000 claims 1
239000003153 chemical reaction reagent Substances 0.000 abstract description 25
238000012545 processing Methods 0.000 abstract description 2
210000004379 membrane Anatomy 0.000 abstract 4
239000000523 sample Substances 0.000 description 37
239000000243 solution Substances 0.000 description 24
239000012491 analyte Substances 0.000 description 19
206010001497 Agitation Diseases 0.000 description 8
238000013019 agitation Methods 0.000 description 8
230000002860 competitive effect Effects 0.000 description 8
238000011534 incubation Methods 0.000 description 8
238000012360 testing method Methods 0.000 description 8
102000004190 Enzymes Human genes 0.000 description 5
108090000790 Enzymes Proteins 0.000 description 5
241001203952 Feia Species 0.000 description 5
238000003556 assay Methods 0.000 description 5
230000009850 completed effect Effects 0.000 description 5
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
230000002572 peristaltic effect Effects 0.000 description 4
238000005259 measurement Methods 0.000 description 3
238000003127 radioimmunoassay Methods 0.000 description 3
239000002699 waste material Substances 0.000 description 3
238000013459 approach Methods 0.000 description 2
229920002678 cellulose Polymers 0.000 description 2
239000001913 cellulose Substances 0.000 description 2
238000005558 fluorometry Methods 0.000 description 2
238000011068 loading method Methods 0.000 description 2
239000002245 particle Substances 0.000 description 2
230000036647 reaction Effects 0.000 description 2
230000000452 restraining effect Effects 0.000 description 2
230000035945 sensitivity Effects 0.000 description 2
239000002002 slurry Substances 0.000 description 2
238000009736 wetting Methods 0.000 description 2
102000002260 Alkaline Phosphatase Human genes 0.000 description 1
108020004774 Alkaline Phosphatase Proteins 0.000 description 1
241000283707 Capra Species 0.000 description 1
241000283973 Oryctolagus cuniculus Species 0.000 description 1
229910019142 PO4 Inorganic materials 0.000 description 1
238000002835 absorbance Methods 0.000 description 1
238000010936 aqueous wash Methods 0.000 description 1
230000008901 benefit Effects 0.000 description 1
230000003197 catalytic effect Effects 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
238000002967 competitive immunoassay Methods 0.000 description 1
238000011109 contamination Methods 0.000 description 1
238000010586 diagram Methods 0.000 description 1
239000003814 drug Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
238000006911 enzymatic reaction Methods 0.000 description 1
108010074605 gamma-Globulins Proteins 0.000 description 1
230000000977 initiatory effect Effects 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
238000005375 photometry Methods 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
238000005086 pumping Methods 0.000 description 1
239000007790 solid phase Substances 0.000 description 1
238000002834 transmittance Methods 0.000 description 1
238000005406 washing Methods 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Clinical Laboratory Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Automatic Analysis And Handling Materials Therefor (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

CA000506891A 1985-04-18 1986-04-17 Porous hydrophobic membrane and method of using same Expired - Lifetime CA1279005C (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US72471185A	1985-04-18	1985-04-18
US724,711		1985-04-18

Publications (1)

Publication Number	Publication Date
CA1279005C true CA1279005C (en)	1991-01-15

Family

ID=24911571

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000506891A Expired - Lifetime CA1279005C (en)	1985-04-18	1986-04-17	Porous hydrophobic membrane and method of using same

Country Status (4)

Country	Link
EP (1)	EP0226600A1 (ja)
JP (1)	JPH0731204B2 (ja)
CA (1)	CA1279005C (ja)
WO (1)	WO1986006004A1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4952516A (en) *	1987-06-12	1990-08-28	Pall Corporation	Self-venting diagnostic test device
DE3874010T2 (de) *	1987-06-12	1993-01-07	Pall Corp	Diagnostische testvorrichtung.
US4902481A (en) *	1987-12-11	1990-02-20	Millipore Corporation	Multi-well filtration test apparatus
JP2515391B2 (ja) *	1989-03-02	1996-07-10	日本電子株式会社	自動免疫測定装置
JP2515392B2 (ja) *	1989-03-02	1996-07-10	日本電子株式会社	自動免疫測定装置
JP2739499B2 (ja) *	1989-06-22	1998-04-15	ミリポア・コーポレイション	マルチウエル▲ろ▼過試験装置
NL1004609C2 (nl) *	1996-11-25	1998-06-05	Pannevis Bv	Scheidingsinrichting.
CN108855985B (zh) *	2018-08-01	2023-12-15	成都瑞拓科技有限责任公司	湿珠胶囊偏心度检测装置及其检测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1354286A (en) *	1970-05-13	1974-05-22	Bagshawe K D	Performance of routine chemical reactions
FR2091793A5 (en) *	1970-05-20	1972-01-14	Wilson Pharm & Chem Corp	Aqueous soln separator - using pressure sensitive membrane in contact - with suspensions
SE8102316L (sv) *	1981-04-10	1982-10-11	Pharmacia Diagnostics Ab	Anordning for genomforande av analyser
NZ201901A (en) *	1981-09-25	1986-11-12	Commw Serum Lab Commission	An apparatus suitable for performing automated heterogeneous immunoassays in a plurality of samples
JPS6017358A (ja) *	1983-03-08	1985-01-29	Konishiroku Photo Ind Co Ltd	分析容器
GB2139519B (en) *	1983-04-29	1986-03-05	Kenneth Dawson Bagshawe	Reaction-chamber and filter for chemical analysis

1986
- 1986-04-07 WO PCT/US1986/000746 patent/WO1986006004A1/en not_active Ceased
- 1986-04-07 JP JP61502435A patent/JPH0731204B2/ja not_active Expired - Lifetime
- 1986-04-07 EP EP19860902967 patent/EP0226600A1/en not_active Withdrawn
- 1986-04-17 CA CA000506891A patent/CA1279005C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPS62502706A (ja)	1987-10-15
WO1986006004A1 (en)	1986-10-23
JPH0731204B2 (ja)	1995-04-10
EP0226600A1 (en)	1987-07-01

Legal Events

Date	Code	Title	Description
1994-07-16	MKLA	Lapsed

Publication	Publication Date	Title
US4871683A (en)	1989-10-03	Apparatus and method using a new reaction capsule
US3489525A (en)	1970-01-13	System of automatic analysis
EP1316869B1 (en)	2008-08-06	Improvements in or relating to a fluid metering system
US7855084B2 (en)	2010-12-21	Chemistry system for clinical analyzer
US4816418A (en)	1989-03-28	Method and apparatus for performing automated, multi-sequential immunoassays
JP3535144B2 (ja)	2004-06-07	自動連続ランダムアクセス分析システムおよびその構成要素
US5079959A (en)	1992-01-14	Analyzing system using sheath flow of sample
EP0281201A1 (en)	1988-09-07	Self contained immunoassay element
US6299839B1 (en)	2001-10-09	System and methods for performing rotor assays
JPS63281053A (ja)	1988-11-17	カートリッジ及び固相免疫検定を行うための方法
JPS58501521A (ja)	1983-09-08	自動免疫定量システム
JPH01229969A (ja)	1989-09-13	改良されたメンブレン支持形式の免疫分析法
JPH01229944A (ja)	1989-09-13	ルミノメータに使用される噴射システムおよびルミノメータの試料中に液体を噴射する方法
CA1279005C (en)	1991-01-15	Porous hydrophobic membrane and method of using same
US20090114255A1 (en)	2009-05-07	Cleaning apparatus and automatic analyzer
JPH04115136A (ja)	1992-04-16	粒子計測装置
JP3418329B2 (ja)	2003-06-23	試料分注方法及び自動分析装置
JP2883347B2 (ja)	1999-04-19	自動免疫測定装置のカートリッジ洗浄装置
JPH02243960A (ja)	1990-09-28	分析装置の分注器操作方式
JPH02228562A (ja)	1990-09-11	自動免疫測定装置
JPH06288916A (ja)	1994-10-18	生化学分析方法
JP3189586B2 (ja)	2001-07-16	自動分析装置
Natelson	1968	Automatic analysis of microsamples contained in capillaries with a microsample dispenser
JP2515391B2 (ja)	1996-07-10	自動免疫測定装置
JPH11271313A (ja)	1999-10-08	生化学分析装置