CA1293679C - Dispositif pour empecher le transfert de diluant - Google Patents
Dispositif pour empecher le transfert de diluantInfo
- Publication number
- CA1293679C CA1293679C CA000533941A CA533941A CA1293679C CA 1293679 C CA1293679 C CA 1293679C CA 000533941 A CA000533941 A CA 000533941A CA 533941 A CA533941 A CA 533941A CA 1293679 C CA1293679 C CA 1293679C
- Authority
- CA
- Canada
- Prior art keywords
- cuvette
- sample
- diluent
- probe
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003085 diluting agent Substances 0.000 title claims abstract description 60
- 239000000523 sample Substances 0.000 claims abstract description 204
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 87
- 239000007788 liquid Substances 0.000 claims description 67
- 239000000463 material Substances 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 19
- 239000012472 biological sample Substances 0.000 claims description 11
- 238000011109 contamination Methods 0.000 claims description 9
- 238000011010 flushing procedure Methods 0.000 claims description 7
- 239000013610 patient sample Substances 0.000 abstract description 19
- 239000012530 fluid Substances 0.000 abstract description 10
- 238000010790 dilution Methods 0.000 abstract description 3
- 239000012895 dilution Substances 0.000 abstract description 3
- 239000000243 solution Substances 0.000 abstract description 2
- 238000002156 mixing Methods 0.000 description 61
- 238000004458 analytical method Methods 0.000 description 43
- 238000006243 chemical reaction Methods 0.000 description 27
- 238000012360 testing method Methods 0.000 description 26
- 238000012546 transfer Methods 0.000 description 13
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 12
- 238000011068 loading method Methods 0.000 description 11
- 238000007792 addition Methods 0.000 description 9
- 239000000470 constituent Substances 0.000 description 8
- 230000003287 optical effect Effects 0.000 description 7
- BCHLTFOMLWCYIS-UHFFFAOYSA-N 4-amino-5-chloro-n-[2-(diethylamino)ethyl]-2-methoxybenzamide;n-(4-hydroxyphenyl)acetamide;hydrochloride Chemical compound Cl.CC(=O)NC1=CC=C(O)C=C1.CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC BCHLTFOMLWCYIS-UHFFFAOYSA-N 0.000 description 6
- 230000001154 acute effect Effects 0.000 description 6
- 238000004090 dissolution Methods 0.000 description 6
- 229910052742 iron Inorganic materials 0.000 description 6
- 230000005499 meniscus Effects 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 230000001276 controlling effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000007787 solid Substances 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 239000011541 reaction mixture Substances 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000004913 activation Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000012864 cross contamination Methods 0.000 description 2
- 230000000994 depressogenic effect Effects 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000002985 plastic film Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 230000001960 triggered effect Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 229920001634 Copolyester Polymers 0.000 description 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 1
- 229920003182 Surlyn® Polymers 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000013101 initial test Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229920006230 thermoplastic polyester resin Polymers 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
- G01N2035/102—Preventing or detecting loss of fluid by dripping
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N2035/1025—Fluid level sensing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
- G01N2035/1086—Cylindrical, e.g. variable angle
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85821786A | 1986-04-30 | 1986-04-30 | |
| US858,217 | 1986-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1293679C true CA1293679C (fr) | 1991-12-31 |
Family
ID=25327772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000533941A Expired - Lifetime CA1293679C (fr) | 1986-04-30 | 1987-04-06 | Dispositif pour empecher le transfert de diluant |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS63503245A (fr) |
| CA (1) | CA1293679C (fr) |
| WO (1) | WO1987006695A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9208386D0 (en) * | 1992-04-16 | 1992-06-03 | Amersham Int Plc | Storage and dispensing device for liquids |
| JP3567187B2 (ja) * | 1995-02-23 | 2004-09-22 | アークレイ株式会社 | 試料液等の撹拌装置 |
| US7648678B2 (en) | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2623307A1 (de) * | 1976-05-25 | 1977-12-08 | Bodenseewerk Perkin Elmer Co | Geraet zur automatischen zufuehrung von proben zu einem analysengeraet |
| JPS5848836A (ja) * | 1981-09-18 | 1983-03-22 | Toa Medical Electronics Co Ltd | 光学式自動分析測定装置 |
| US4528158A (en) * | 1982-06-14 | 1985-07-09 | Baird Corporation | Automatic sampling system |
| US4590165A (en) * | 1982-06-14 | 1986-05-20 | Baird Corporation | Automatic sampling system |
| JPS58113761A (ja) * | 1982-08-24 | 1983-07-06 | Olympus Optical Co Ltd | 自動分析装置のサンプル分注方法 |
-
1987
- 1987-04-01 JP JP62502347A patent/JPS63503245A/ja active Pending
- 1987-04-01 WO PCT/US1987/000770 patent/WO1987006695A1/fr not_active Ceased
- 1987-04-06 CA CA000533941A patent/CA1293679C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1987006695A1 (fr) | 1987-11-05 |
| JPS63503245A (ja) | 1988-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKLA | Lapsed |