CA1317244C - Production de formes biologiquement actives de csf a l'aide d'un systeme d'expression baculovirus (acnpv) - cellule d'insecte - Google Patents

Production de formes biologiquement actives de csf a l'aide d'un systeme d'expression baculovirus (acnpv) - cellule d'insecte

Info

Publication number: CA1317244C
Authority: CA; Canada
Prior art keywords: csf; sequence; cells; recombinant baculovirus; baculovirus
Prior art date: 1987-07-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CA000572544A

Other languages

English (en)

Inventor

Ernest Seigo Kawasaki

George Martin

Robin Clark

James Joseph Devlin

Edwin C. O'rourke

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis Vaccines and Diagnostics Inc

Original Assignee

Cetus Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-24

Filing date

1988-07-20

Publication date

1993-05-04

1988-07-20 Application filed by Cetus Corp filed Critical Cetus Corp

1993-05-04 Application granted granted Critical

1993-05-04 Publication of CA1317244C publication Critical patent/CA1317244C/fr

2010-05-04 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

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RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
210000004881 tumor cell Anatomy 0.000 description 1
235000021122 unsaturated fatty acids Nutrition 0.000 description 1
150000004670 unsaturated fatty acids Chemical group 0.000 description 1
210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
238000012795 verification Methods 0.000 description 1
230000009385 viral infection Effects 0.000 description 1
230000017613 viral reproduction Effects 0.000 description 1
230000000007 visual effect Effects 0.000 description 1
238000003260 vortexing Methods 0.000 description 1
239000011534 wash buffer Substances 0.000 description 1
229920003169 water-soluble polymer Polymers 0.000 description 1
210000005253 yeast cell Anatomy 0.000 description 1
239000002076 α-tocopherol Substances 0.000 description 1
235000004835 α-tocopherol Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Virology (AREA)
Immunology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

CA000572544A 1987-07-24 1988-07-20 Production de formes biologiquement actives de csf a l'aide d'un systeme d'expression baculovirus (acnpv) - cellule d'insecte Expired - Lifetime CA1317244C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7718887A	1987-07-24	1987-07-24
US077,188		1993-06-15

Publications (1)

Publication Number	Publication Date
CA1317244C true CA1317244C (fr)	1993-05-04

Family

ID=22136589

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000572544A Expired - Lifetime CA1317244C (fr)	1987-07-24	1988-07-20	Production de formes biologiquement actives de csf a l'aide d'un systeme d'expression baculovirus (acnpv) - cellule d'insecte

Country Status (3)

Country	Link
AU (1)	AU2251488A (fr)
CA (1)	CA1317244C (fr)
WO (1)	WO1989001038A1 (fr)

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JPH04228066A (ja) *	1990-10-23	1992-08-18	Rikagaku Kenkyusho	外来遺伝子発現用培養細胞
US6342216B1 (en) *	1999-03-17	2002-01-29	The Board Of Regents, The University Of Texas System	Therapy of cancer by insect cells containing recombinant baculovirus encoding genes
US6872385B2 (en)	2000-05-31	2005-03-29	Board Of Regents, The University Of Texas System	Adjuvant preparation for the induction of specific immunity
EP2327724A3 (fr)	2004-02-02	2011-07-27	Ambrx, Inc.	Polypeptides d'hormone de croissance humaine et leur utilisations
KR101699142B1 (ko)	2004-06-18	2017-01-23	암브룩스, 인코포레이티드	신규 항원-결합 폴리펩티드 및 이의 용도
JP2008507280A (ja)	2004-07-21	2008-03-13	アンブレツクス・インコーポレイテツド	非天然コードアミノ酸を用いた生合成ポリペプチド
GB2438760A (en)	2004-12-22	2007-12-05	Ambrx Inc	Methods for expression and purification of recombinant human growth hormone
CN102732588B (zh)	2004-12-22	2015-01-07	Ambrx公司	氨酰基-tRNA合成酶的组合物及其用途
US7816320B2 (en)	2004-12-22	2010-10-19	Ambrx, Inc.	Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35
JP2008525473A (ja)	2004-12-22	2008-07-17	アンブレツクス・インコーポレイテツド	修飾されたヒト成長ホルモン
EP1828224B1 (fr)	2004-12-22	2016-04-06	Ambrx, Inc.	Compositions contenant des acides amines non naturels et des polypeptides, procedes impliquant ces acides amines non naturels et polypeptides, et utilisations desdits acides amines non naturels et polypeptides
WO2006133089A2 (fr)	2005-06-03	2006-12-14	Ambrx, Inc.	Molecules d'interferons humains ameliorees et utilisations de celles-ci
MX2008002149A (es)	2005-08-18	2008-04-22	Ambrx Inc	Composiciones de arnt y sus usos.
EP1951890A4 (fr)	2005-11-16	2009-06-24	Ambrx Inc	Procedes et compositions comprenant des acides amines non naturels
MX2009002460A (es)	2006-09-08	2009-03-20	Ambrx Inc	Arnt supresor hibrido para celulas de vertebrados.
CN106008699A (zh)	2006-09-08	2016-10-12	Ambrx公司	经修饰的人类血浆多肽或Fc骨架和其用途
EP2064333B1 (fr)	2006-09-08	2014-02-26	Ambrx, Inc.	Transcription d'arnt suppresseur dans des cellules de vertébrés
CA2682147C (fr)	2007-03-30	2017-08-08	Ambrx, Inc.	Polypeptides fgf-21 modifies, et leurs utilisations
MX2009011870A (es)	2007-05-02	2009-11-12	Ambrx Inc	Polipeptidos de interferon beta modificados y usos de los mismos.
MX2010005317A (es)	2007-11-20	2010-06-02	Ambrx Inc	Polipeptidos de insulina modificados y sus usos.
NZ586947A (en)	2008-02-08	2012-11-30	Ambrx Inc	Modified leptin polypeptides and their uses
PT2318029T (pt)	2008-07-23	2018-01-10	Ambrx Inc	Polipéptidos de g-csf bovino modificados e suas utilizações
PE20110480A1 (es)	2008-09-26	2011-07-01	Ambrx Inc	Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales
MX2011003272A (es)	2008-09-26	2011-04-28	Ambrx Inc	Polipeptidos de eritropoyetina animal modificados y sus usos.
JP2013515081A (ja)	2009-12-21	2013-05-02	アンブルックス，インコーポレイテッド	修飾されているブタのソマトトロピンポリペプチドおよびそれらの使用
NZ600361A (en)	2009-12-21	2014-06-27	Ambrx Inc	Modified bovine somatotropin polypeptides and their uses
MA34521B1 (fr)	2010-08-17	2013-09-02	Ambrx Inc	Polypeptides de relaxine modifiés et leurs utilisations
US9567386B2 (en)	2010-08-17	2017-02-14	Ambrx, Inc.	Therapeutic uses of modified relaxin polypeptides
TWI480288B (zh)	2010-09-23	2015-04-11	Lilly Co Eli	牛顆粒細胞群落刺激因子及其變體之調配物
SMT202100388T1 (it)	2014-10-24	2021-09-14	Bristol Myers Squibb Co	Polipeptidi fgf-21 modificati e loro usi
CN110637027B (zh)	2017-02-08	2024-08-30	百时美施贵宝公司	包含药代动力学增强子的修饰的松弛素多肽及其用途

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IE58011B1 (en) *	1983-05-27	1993-06-16	Texas A & M Univ Sys	Method for producing a recombinant baculovirus expression vector
NZ228031A (en) *	1984-07-06	1991-12-23	Sandoz Ltd	Primate gm-csf and method of extraction
WO1988003173A2 (fr) *	1986-10-24	1988-05-05	Cetus Corporation	Nouvelles formes du facteur-1 de stimulation de colonies

1988
- 1988-07-20 AU AU22514/88A patent/AU2251488A/en not_active Abandoned
- 1988-07-20 CA CA000572544A patent/CA1317244C/fr not_active Expired - Lifetime
- 1988-07-20 WO PCT/US1988/002445 patent/WO1989001038A1/fr not_active Ceased

Also Published As

Publication number	Publication date
AU2251488A (en)	1989-03-01
WO1989001038A1 (fr)	1989-02-09

Legal Events

Date	Code	Title	Description
2010-05-04	MKLA	Lapsed
2012-12-05	MKEC	Expiry (correction)	Effective date: 20121205

Publication	Publication Date	Title
CA1317244C (fr)	1993-05-04	Production de formes biologiquement actives de csf a l'aide d'un systeme d'expression baculovirus (acnpv) - cellule d'insecte
EP0255231B1 (fr)	1992-05-20	Gène humain d'érythropoiétine: expression à haut niveau dans des cellules de mammifères transférées de façon stable
JP2957974B2 (ja)	1999-10-06	エリスロポエチン活性を有するタンパク質の製造方法
Wojchowski et al.	1987	Active human erythropoietin expressed in insect cells using a baculovirus vector: a role for N-linked oligosaccharide
US4965195A (en)	1990-10-23	Interleukin-7
JP2898291B2 (ja)	1999-05-31	昆虫細胞の増殖およびそれによる生産物の発現のための無血清培地
DE69531387T2 (de)	2004-04-22	Von Adenovirus abgeleitete rekombinante Vektoren, für Gentherapie
DE69535680T2 (de)	2008-12-11	Sekretierte, als impfstoffe und diagnostika verwendbare virale cmv-proteine
US6156301A (en)	2000-12-05	Use of interleukin-7 to stimulate proliferation of hematopoietic cell precursors
HU216079B (hu)	1999-04-28	Eljárás eritropoietin előállítására
FI103987B (fi)	1999-10-29	Interleukiini-7
JP2515399B2 (ja)	1996-07-10	ヒト神経成長因子
US5972886A (en)	1999-10-26	Megakaryocyte differentiation factor
DE3853139T2 (de)	1995-06-14	Rekombinanter, fremde gene enthaltender menschlicher cytomegalovirus und seine verwendung.
EP0118977A1 (fr)	1984-09-19	Séquences d'ADN, molécules recombinantes d'ADN et procédés pour la production des polypeptides semblables à interleukin-2 humain
AU1496688A (en)	1988-08-10	Human interleukin-3 proteins
KR100218818B1 (ko)	1999-10-01	항-트롬빈 폴리펩타이드
AU599348B2 (en)	1990-07-19	Method for producing selected polypeptides in virally infected insect cells and polypeptides isolated therefrom
JPH0365191A (ja)	1991-03-20	スフェロイジン単離ｄｎａおよび組み換え昆虫ポックスウィルス発現ベクター
AU713681B2 (en)	1999-12-09	Use of the intracytoplasmic domain of the prolactin receptor or the growth hormone receptor for achieving protein secretion
US5888817A (en)	1999-03-30	Pituitary differentiaton factor and methods of use thereof
AU602097B2 (en)	1990-09-27	Bovine granulocyte-macrophage colony stimulating factor
DE3910084A1 (de)	1989-11-16	Polypeptide mit wachstumsfaktor-aktivitaet und nukleinsaeuresequenzen
GB2276622A (en)	1994-10-05	Mollusc polypeptides as insecticides, and DNA thereof
AU630075B2 (en)	1992-10-22	Cloning and expression of transforming growth factor 2b