CA2001444A1 - Electrode d'iontophorese - Google Patents

Electrode d'iontophorese

Info

Publication number
CA2001444A1
CA2001444A1 CA2001444A CA2001444A CA2001444A1 CA 2001444 A1 CA2001444 A1 CA 2001444A1 CA 2001444 A CA2001444 A CA 2001444A CA 2001444 A CA2001444 A CA 2001444A CA 2001444 A1 CA2001444 A1 CA 2001444A1
Authority
CA
Canada
Prior art keywords
iontophoresis electrode
drug
skin
ionic
drug reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2001444A
Other languages
English (en)
Other versions
CA2001444C (fr
Inventor
Darrel F. Untereker
Joseph B. Phipps
Patrick T. Cahalan
Kenneth R. Brennen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Publication of CA2001444A1 publication Critical patent/CA2001444A1/fr
Application granted granted Critical
Publication of CA2001444C publication Critical patent/CA2001444C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444—Membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Medicinal Preparation (AREA)
CA002001444A 1988-10-28 1989-10-25 Electrode d'iontophorese Expired - Lifetime CA2001444C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26423888A 1988-10-28 1988-10-28
US07/264,238 1988-10-28

Publications (2)

Publication Number Publication Date
CA2001444A1 true CA2001444A1 (fr) 1990-04-28
CA2001444C CA2001444C (fr) 2000-07-25

Family

ID=23005166

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002001444A Expired - Lifetime CA2001444C (fr) 1988-10-28 1989-10-25 Electrode d'iontophorese

Country Status (11)

Country Link
US (1) US5395310A (fr)
EP (1) EP0400118B1 (fr)
JP (1) JP2939550B2 (fr)
AU (1) AU621417B2 (fr)
CA (1) CA2001444C (fr)
DE (1) DE68927476T2 (fr)
ES (1) ES2017187A6 (fr)
MX (1) MX174131B (fr)
NO (1) NO305468B1 (fr)
NZ (1) NZ231164A (fr)
WO (1) WO1990004433A1 (fr)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
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US6956032B1 (en) 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
AU2286995A (en) * 1994-04-08 1995-10-30 Alza Corporation Electrotransport system with ion exchange competitive ion capture
JP3523334B2 (ja) * 1994-07-02 2004-04-26 久光製薬株式会社 イオントフォレ−シス用プラスター構造体
US5990179A (en) * 1995-04-28 1999-11-23 Alza Corporation Composition and method of enhancing electrotransport agent delivery
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JP3459724B2 (ja) * 1996-03-17 2003-10-27 久光製薬株式会社 イオントフォレーシス用電極デバイス
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WO1997048443A1 (fr) * 1996-06-19 1997-12-24 Becton Dickinson And Company Administration iontophoretique d'inhibiteurs de l'adhesion cellulaire
US6119036A (en) 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
CA2308489A1 (fr) 1997-10-09 1999-04-22 Emory University Procede et dispositif d'administration transdermique du lithium
US6775569B2 (en) * 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
JP4154016B2 (ja) 1997-12-30 2008-09-24 久光製薬株式会社 イオントフォレーシス装置およびその組み立て方法
ES2232111T3 (es) * 1998-01-28 2005-05-16 Alza Corporation Conjunto de electrodo de electrotransporte que presenta una menor resistencia inicial.
JPH11239621A (ja) 1998-02-25 1999-09-07 Hisamitsu Pharmaceut Co Inc イオントフォレーシス装置
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US7127285B2 (en) * 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6553253B1 (en) 1999-03-12 2003-04-22 Biophoretic Therapeutic Systems, Llc Method and system for electrokinetic delivery of a substance
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
WO2000061220A1 (fr) 1999-04-13 2000-10-19 Hisamitsu Pharmaceutical Co., Inc. Dispositif d'iontophorese
CA2400325A1 (fr) 2000-02-18 2001-08-23 University Of Utah Research Foundation Procede d'apport d'agents au moyen de courant alternatif
JP2003522613A (ja) 2000-02-18 2003-07-29 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション 交流を用いて物質を抽出する方法
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
SK2312004A3 (en) 2001-10-31 2004-10-05 R & R Ventures Inc Iontophoresis device
HUP0402663A2 (hu) * 2001-12-20 2005-06-28 Alza Corporation Egybeöntött tárolóelemházzal ellátott eszköz elektrotranszporthoz
US7734339B2 (en) 2002-11-27 2010-06-08 Tokuyama Corporation Iontophoresis apparatus
JP2004202057A (ja) 2002-12-26 2004-07-22 Tokuyama Corp イオン性薬剤封入袋状物
US7479132B2 (en) 2003-03-10 2009-01-20 Tokuyama Corporation Patch material for ionic medicine administration
JP2005334263A (ja) * 2004-05-26 2005-12-08 Tokuyama Corp イオントフォレーシス装置及びイオン交換膜
JP4615929B2 (ja) * 2004-08-11 2011-01-19 久光製薬株式会社 イオントフォレーシス装置
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
JP4728631B2 (ja) * 2004-11-30 2011-07-20 Tti・エルビュー株式会社 イオントフォレーシス装置
US7590444B2 (en) 2004-12-09 2009-09-15 Tti Ellebeau, Inc. Iontophoresis device
JP4731931B2 (ja) * 2005-02-03 2011-07-27 Tti・エルビュー株式会社 イオントフォレーシス装置
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
JP4793806B2 (ja) 2005-03-22 2011-10-12 Tti・エルビュー株式会社 イオントフォレーシス装置
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
JP2006334164A (ja) * 2005-06-02 2006-12-14 Transcutaneous Technologies Inc イオントフォレーシス装置及びその制御方法
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
US20070027426A1 (en) * 2005-06-24 2007-02-01 Transcutaneous Technologies Inc. Iontophoresis device to deliver active agents to biological interfaces
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
JPWO2007023907A1 (ja) * 2005-08-24 2009-02-26 Tti・エルビュー株式会社 冷凍型イオントフォレーシス用電極構造体
CN101252968A (zh) * 2005-09-15 2008-08-27 Tti优而美株式会社 棒式离子电渗疗装置
AU2006289888B2 (en) * 2005-09-16 2010-12-02 Tti Ellebeau, Inc. Catheter type iontophoresis apparatus
JPWO2007037324A1 (ja) * 2005-09-28 2009-04-09 Tti・エルビュー株式会社 乾燥型イオントフォレーシス用電極構造体
WO2007041526A2 (fr) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Appareil de ionophorese et procede d'apport d'antibiotiques vers des interfaces biologiques
WO2007041115A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau Inc. Procede et systeme de detection de dysfonctionnements dans un dispositif de ionophorese qui apporte des agents actifs a des interfaces biologiques
EP1928539A1 (fr) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Systemes, dispositifs et procedes d'apport de medicament transdermique a micro-aiguilles fonctionnalisees
RU2008117153A (ru) * 2005-09-30 2009-11-10 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Аппарат для ионтофореза, доставляющий множество активных агентов к биологическим барьерам
EP1931417A2 (fr) * 2005-09-30 2008-06-18 Transcutaneous Technologies Inc. Systemes d'administration transdermique de medicament, dispositifs, et methodes faisant intervenir de nouveaux excipients pharmaceutiques
JP2009509676A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 ナノ粒子と接合された活性物質のイオントフォレーシス送達
US20070081944A1 (en) * 2005-09-30 2007-04-12 Reed Steven G Iontophoresis apparatus and method for the diagnosis of tuberculosis
CA2664589A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Dispositif d'iontophorese et methode d'administration d'agents actifs a une interface biologique
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
WO2007041434A2 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Appareil de ionophorese et procede d'apport de facteurs angiogeniques de façon a renforcer la guerison de tissus endommages
WO2007041323A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Apport ionophoretique d'agents actifs encapsules dans des vesicules
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
EP1944057A4 (fr) * 2005-09-30 2009-02-18 Tti Ellebeau Inc Appareil d'iontophorese capable de regler la dose et l'heure d'administration d'un inducteur de sommeil et d'un agent analeptique
WO2007037475A1 (fr) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. Structure d’électrode pour iontophorèse comprenant un séparateur à mémoire de forme, et appareil de iontophorèse comprenant ladite structure
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
WO2008027440A2 (fr) * 2006-08-29 2008-03-06 Tti Ellebeau, Inc. Dispositif d'iontophorèse et procédé de fonctionnement avec une source de puissance usb (bus sériel universel)
WO2008030497A2 (fr) 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Système d'administration transdermique de médicaments par des alimentations en courant inductif
KR20090060272A (ko) * 2006-09-05 2009-06-11 티티아이 엘뷰 가부시키가이샤 화합물의 이온 영동 특성을 평가하기 위한 임피던스 시스템, 장치 및 방법
WO2008030496A2 (fr) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Systèmes, dispositifs et procédés non destructeurs pour évaluer des dispositifs de libération de médicament pour ionophorèse
US8332028B2 (en) * 2006-11-28 2012-12-11 Polyplus Battery Company Protected lithium electrodes for electro-transport drug delivery
WO2008082558A2 (fr) 2006-12-20 2008-07-10 Alza Corporation Anode pour l'électrotransport d'un médicament cationique
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
CA2724949A1 (fr) 2007-06-27 2008-12-31 The General Hospital Corporation Procede et appareil d'inhibition optique de traitement photodynamique
US20090005824A1 (en) * 2007-06-29 2009-01-01 Polyplus Battery Company Electrotransport devices, methods and drug electrode assemblies
US20090105634A1 (en) * 2007-10-17 2009-04-23 Alza Corporation Anodic Reservoir for Electrotransport of Cationic Drug
US20090105632A1 (en) * 2007-10-18 2009-04-23 Padmanabhan Rama V Electrotransport Of Lisuride
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
KR101674904B1 (ko) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 중재형 약물전달 시스템과 그 방법
EP2627292B1 (fr) 2010-10-15 2018-10-10 Clearside Biomedical, Inc. Dispositif pour accès oculaire
AU2014259694B2 (en) 2013-05-03 2018-11-08 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
EP3397340A1 (fr) * 2015-12-30 2018-11-07 L'Oréal Système de massage par ionisation
WO2017192565A1 (fr) * 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systèmes et méthodes pour l'administration de médicaments par voie ophtalmique
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery

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Also Published As

Publication number Publication date
ES2017187A6 (es) 1991-01-01
NO305468B1 (no) 1999-06-07
JP2939550B2 (ja) 1999-08-25
CA2001444C (fr) 2000-07-25
EP0400118B1 (fr) 1996-11-20
MX174131B (es) 1994-04-22
DE68927476T2 (de) 1997-03-27
JPH03504343A (ja) 1991-09-26
EP0400118A1 (fr) 1990-12-05
NZ231164A (en) 1992-02-25
US5395310A (en) 1995-03-07
WO1990004433A1 (fr) 1990-05-03
DE68927476D1 (de) 1997-01-02
AU621417B2 (en) 1992-03-12
NO902853D0 (no) 1990-06-27
EP0400118A4 (en) 1992-06-10
AU4509989A (en) 1990-05-14
NO902853L (no) 1990-08-27

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