CA2004606A1 - Procede de preparation de derives optiquement actifs de la 2-oxoimidazolidine - Google Patents

Procede de preparation de derives optiquement actifs de la 2-oxoimidazolidine

Info

Publication number
CA2004606A1
CA2004606A1 CA2004606A CA2004606A CA2004606A1 CA 2004606 A1 CA2004606 A1 CA 2004606A1 CA 2004606 A CA2004606 A CA 2004606A CA 2004606 A CA2004606 A CA 2004606A CA 2004606 A1 CA2004606 A1 CA 2004606A1
Authority
CA
Canada
Prior art keywords
optically active
oxoimidazolidine
preparing optically
group
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2004606A
Other languages
English (en)
Other versions
CA2004606C (fr
Inventor
Kimiaki Hayashi
Hitoshi Kubota
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of CA2004606A1 publication Critical patent/CA2004606A1/fr
Application granted granted Critical
Publication of CA2004606C publication Critical patent/CA2004606C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • C07D233/38One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA002004606A 1988-12-16 1989-12-05 Procede de preparation de derives optiquement actifs de la 2-oxoimidazolidine Expired - Lifetime CA2004606C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63318745A JPH0645603B2 (ja) 1988-12-16 1988-12-16 光学活性2‐オキソイミダゾリジン誘導体の製法
JP318745/1988 1988-12-16

Publications (2)

Publication Number Publication Date
CA2004606A1 true CA2004606A1 (fr) 1990-06-16
CA2004606C CA2004606C (fr) 1997-01-07

Family

ID=18102470

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002004606A Expired - Lifetime CA2004606C (fr) 1988-12-16 1989-12-05 Procede de preparation de derives optiquement actifs de la 2-oxoimidazolidine

Country Status (17)

Country Link
US (1) US5013845A (fr)
EP (1) EP0373881B1 (fr)
JP (1) JPH0645603B2 (fr)
KR (1) KR950009364B1 (fr)
CN (1) CN1032308C (fr)
AT (1) ATE100817T1 (fr)
AU (1) AU622959B2 (fr)
CA (1) CA2004606C (fr)
DE (1) DE68912745T2 (fr)
DK (1) DK174701B1 (fr)
ES (1) ES2062044T3 (fr)
FI (1) FI97133C (fr)
HK (1) HK34195A (fr)
HU (1) HU203730B (fr)
IE (1) IE64315B1 (fr)
IL (1) IL92456A0 (fr)
SG (1) SG4795G (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104513292A (zh) * 2013-09-29 2015-04-15 山东新时代药业有限公司 一种雷米普利的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5788165A (en) * 1980-11-21 1982-06-01 Tanabe Seiyaku Co Ltd 2-oxoimidazolidine-4-carboxylic acid derivative and its preparation
JPS6058233B2 (ja) * 1982-05-24 1985-12-19 田辺製薬株式会社 2−オキソイミダゾリジン誘導体及びその製法
JPS6058233A (ja) * 1983-08-11 1985-04-04 ザ・アプジヨン・カンパニー 滅菌懸濁液及び溶液の保持及び混合装置

Also Published As

Publication number Publication date
HK34195A (en) 1995-03-17
US5013845A (en) 1991-05-07
HU896640D0 (en) 1990-02-28
EP0373881A3 (en) 1990-08-16
DK638289D0 (da) 1989-12-15
DK174701B1 (da) 2003-09-29
EP0373881B1 (fr) 1994-01-26
AU4619589A (en) 1990-06-21
IE64315B1 (en) 1995-07-26
CN1043705A (zh) 1990-07-11
KR950009364B1 (ko) 1995-08-21
ATE100817T1 (de) 1994-02-15
FI97133B (fi) 1996-07-15
IE894004L (en) 1990-06-16
SG4795G (en) 1995-06-16
CA2004606C (fr) 1997-01-07
HUT52064A (en) 1990-06-28
HU203730B (en) 1991-09-30
CN1032308C (zh) 1996-07-17
FI895795A0 (fi) 1989-12-04
DK638289A (da) 1990-06-17
AU622959B2 (en) 1992-04-30
JPH0645603B2 (ja) 1994-06-15
EP0373881A2 (fr) 1990-06-20
DE68912745D1 (de) 1994-03-10
JPH02164869A (ja) 1990-06-25
ES2062044T3 (es) 1994-12-16
IL92456A0 (en) 1990-08-31
DE68912745T2 (de) 1994-05-11
FI97133C (fi) 1996-10-25
KR900009603A (ko) 1990-07-05

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Legal Events

Date Code Title Description
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