CA2006358A1 - Methode de preparation de polyazamacrocycles mono-n-alkyles - Google Patents

Methode de preparation de polyazamacrocycles mono-n-alkyles

Info

Publication number
CA2006358A1
CA2006358A1 CA2006358A CA2006358A CA2006358A1 CA 2006358 A1 CA2006358 A1 CA 2006358A1 CA 2006358 A CA2006358 A CA 2006358A CA 2006358 A CA2006358 A CA 2006358A CA 2006358 A1 CA2006358 A1 CA 2006358A1
Authority
CA
Canada
Prior art keywords
preparing mono
polyazamacrocycles
alkylated
alkylated polyazamacrocycles
mono
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2006358A
Other languages
English (en)
Other versions
CA2006358C (fr
Inventor
William J. Kruper, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2006358A1 publication Critical patent/CA2006358A1/fr
Application granted granted Critical
Publication of CA2006358C publication Critical patent/CA2006358C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • H—ELECTRICITY
    • H03—ELECTRONIC CIRCUITRY
    • H03K—PULSE TECHNIQUE
    • H03K19/00—Logic circuits, i.e. having at least two inputs acting on one output; Inverting circuits
    • H03K19/02—Logic circuits, i.e. having at least two inputs acting on one output; Inverting circuits using specified components
    • H03K19/08—Logic circuits, i.e. having at least two inputs acting on one output; Inverting circuits using specified components using semiconductor devices
    • H03K19/094—Logic circuits, i.e. having at least two inputs acting on one output; Inverting circuits using specified components using semiconductor devices using field-effect transistors
    • H03K19/09432—Logic circuits, i.e. having at least two inputs acting on one output; Inverting circuits using specified components using semiconductor devices using field-effect transistors with coupled sources or source coupled logic
    • H03K19/09436—Source coupled field-effect logic [SCFL]
    • H—ELECTRICITY
    • H03—ELECTRONIC CIRCUITRY
    • H03K—PULSE TECHNIQUE
    • H03K3/00—Circuits for generating electric pulses; Monostable, bistable or multistable circuits
    • H03K3/02—Generators characterised by the type of circuit or by the means used for producing pulses
    • H03K3/353—Generators characterised by the type of circuit or by the means used for producing pulses by the use, as active elements, of field-effect transistors with internal or external positive feedback
    • H03K3/356—Bistable circuits
    • H03K3/3565—Bistables with hysteresis, e.g. Schmitt trigger

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Computer Hardware Design (AREA)
  • General Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Physics & Mathematics (AREA)
  • Power Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
CA002006358A 1988-12-22 1989-12-21 Methode de preparation de polyazamacrocycles mono-n-alkyles Expired - Fee Related CA2006358C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28916388A 1988-12-22 1988-12-22
US289,163 1988-12-22

Publications (2)

Publication Number Publication Date
CA2006358A1 true CA2006358A1 (fr) 1990-06-22
CA2006358C CA2006358C (fr) 1998-07-07

Family

ID=23110317

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002006358A Expired - Fee Related CA2006358C (fr) 1988-12-22 1989-12-21 Methode de preparation de polyazamacrocycles mono-n-alkyles

Country Status (19)

Country Link
EP (1) EP0374929B1 (fr)
JP (1) JP2930709B2 (fr)
KR (1) KR0160113B1 (fr)
CN (1) CN1028172C (fr)
BR (1) BR8907277A (fr)
CA (1) CA2006358C (fr)
DE (1) DE68928619T2 (fr)
DK (1) DK175509B1 (fr)
ES (1) ES2113846T3 (fr)
FI (1) FI104171B (fr)
GR (1) GR3026745T3 (fr)
HK (1) HK1008425A1 (fr)
HU (1) HU208317B (fr)
IL (1) IL92844A (fr)
NO (1) NO177496C (fr)
PH (1) PH30234A (fr)
PT (1) PT92638B (fr)
SG (1) SG47867A1 (fr)
WO (1) WO1990007261A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5316757A (en) * 1984-10-18 1994-05-31 Board Of Regents, The University Of Texas System Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups
US5362476A (en) * 1984-10-18 1994-11-08 Board Of Regents, The University Of Texas System Alkyl phosphonate polyazamacrocyclic cheates for MRI
FR2654102B1 (fr) * 1989-11-09 1992-01-10 Air Liquide Procede de synthese de derives polyazotes cycliques.
FR2672051B1 (fr) * 1991-01-24 1993-05-21 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes polymetalliques, composition de diagnostic et therapeutique.
CA2072934C (fr) * 1991-07-19 2007-08-28 Karl William Aston Complexes de manganese et de ligands macrocycliques contenant de l'azote, efficaces comme catalyseurs de la dismutation de superoxydes
US5410043A (en) * 1991-12-06 1995-04-25 Schering Aktiengesellschaft Process for the production of mono-N-substituted tetraaza macrocycles
DE4218744C2 (de) * 1992-06-04 1997-11-06 Schering Ag Verfahren zur Herstellung von N-ß-Hxdroxyalkyl-tri-N-carboxylalkyl-1,4,7,10-tetraazacyclododecan- und N-ß-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivaten und deren Metallkomplexe
EP0588229A3 (en) * 1992-09-12 1994-06-15 Hoechst Ag Macrocyclic chelating agents for the preparation of technetium or rhenium complexes
US6204259B1 (en) 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
GB9504910D0 (en) * 1995-03-10 1995-04-26 Nycomed Imaging As Compounds
US5612478A (en) * 1995-03-30 1997-03-18 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
US5606053A (en) * 1995-05-02 1997-02-25 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
US6525041B1 (en) 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
US5608061A (en) * 1995-08-02 1997-03-04 Johnson Matthey Plc Process for preparing 1,4,8,11-tetraazacyclotetradecane
EP0846003A1 (fr) 1995-08-17 1998-06-10 Monsanto Company Methodes d'analyse d'images diagnostiques utilisant des conjugues biologiques de complexes metalliques de ligands macrocycliques renfermant de l'azote
BR112013000236B1 (pt) * 2010-07-06 2018-11-13 Catexel Limited método de produzir um composto, e, sal protonado
CN114560829B (zh) * 2022-03-17 2023-08-04 中山大学 一种大环单体的制备方法及其开环聚合反应

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60559C (fi) * 1975-07-17 1982-02-10 Sumitomo Chemical Co Foerfarande foer framstaellning av ny-(tertiaer amino)-orto-aminobutyrofenonfoereningar
EP0232751B1 (fr) * 1986-01-23 1991-09-11 E.R. Squibb & Sons, Inc. 4,7,10-Triscarboxyméthyl-1,4,7,10-tétraazacyclododécane substitué en position 1 et analogues
JPS6314780A (ja) * 1986-07-08 1988-01-21 Tosoh Corp クラウンエ−テル連結大環状ポリアミン類およびその製造法
FR2613718B1 (fr) * 1987-04-10 1990-12-14 Centre Nat Rech Scient Tetramines cycliques monofonctionnalisees, leur procede de preparation, leurs polymeres et utilisation de ces polymeres
US4994560A (en) * 1987-06-24 1991-02-19 The Dow Chemical Company Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies

Also Published As

Publication number Publication date
NO895176L (no) 1990-06-25
HU896728D0 (en) 1990-03-28
KR0160113B1 (ko) 1998-12-01
CA2006358C (fr) 1998-07-07
IL92844A0 (en) 1990-09-17
JP2930709B2 (ja) 1999-08-03
EP0374929A1 (fr) 1990-06-27
DE68928619D1 (de) 1998-04-30
DK665489A (da) 1990-06-23
DK665489D0 (da) 1989-12-22
PH30234A (en) 1997-02-05
CN1028172C (zh) 1995-04-12
GR3026745T3 (en) 1998-07-31
NO177496B (no) 1995-06-19
CN1044096A (zh) 1990-07-25
WO1990007261A3 (fr) 1990-11-29
DK175509B1 (da) 2004-11-15
FI104171B1 (fi) 1999-11-30
ES2113846T3 (es) 1998-05-16
BR8907277A (pt) 1991-03-26
JPH02503141A (ja) 1990-09-27
HK1008425A1 (en) 1999-05-07
PT92638A (pt) 1990-06-29
FI104171B (fi) 1999-11-30
WO1990007261A2 (fr) 1990-07-12
KR900009790A (ko) 1990-07-05
NO177496C (no) 1995-09-27
FI896171A0 (fi) 1989-12-21
DE68928619T2 (de) 1998-07-16
NO895176D0 (no) 1989-12-21
HU208317B (en) 1993-09-28
SG47867A1 (en) 1998-04-17
EP0374929B1 (fr) 1998-03-25
HUT52487A (en) 1990-07-28
IL92844A (en) 1994-11-28
PT92638B (pt) 1995-09-12

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