CA2010272A1 - Benzenesulfonamides et procede de preparation - Google Patents

Benzenesulfonamides et procede de preparation

Info

Publication number
CA2010272A1
CA2010272A1 CA2010272A CA2010272A CA2010272A1 CA 2010272 A1 CA2010272 A1 CA 2010272A1 CA 2010272 A CA2010272 A CA 2010272A CA 2010272 A CA2010272 A CA 2010272A CA 2010272 A1 CA2010272 A1 CA 2010272A1
Authority
CA
Canada
Prior art keywords
carbon atoms
alkyl
hydrogen
preparation
tert
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2010272A
Other languages
English (en)
Other versions
CA2010272C (fr
Inventor
Hans-Jochen Lang
Ernold Granzer
Bela Kerekjarto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2010272A1 publication Critical patent/CA2010272A1/fr
Application granted granted Critical
Publication of CA2010272C publication Critical patent/CA2010272C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K31/00—Housing birds
    • A01K31/18—Chicken coops or houses for baby chicks; Brooders including auxiliary features, e.g. feeding, watering, demanuring, heating, ventilation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Paper (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002010272A 1989-02-18 1990-02-16 Benzenesulfonamides et procede de preparation Expired - Lifetime CA2010272C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3905075.0 1989-02-18
DE3905075A DE3905075A1 (de) 1989-02-18 1989-02-18 Benzolsulfonamide und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
CA2010272A1 true CA2010272A1 (fr) 1990-08-18
CA2010272C CA2010272C (fr) 1999-11-16

Family

ID=6374463

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002010272A Expired - Lifetime CA2010272C (fr) 1989-02-18 1990-02-16 Benzenesulfonamides et procede de preparation

Country Status (17)

Country Link
US (1) US5143937A (fr)
EP (1) EP0384279B1 (fr)
JP (1) JP2851108B2 (fr)
KR (1) KR0175298B1 (fr)
AT (1) ATE104273T1 (fr)
AU (1) AU622765B2 (fr)
CA (1) CA2010272C (fr)
DE (2) DE3905075A1 (fr)
DK (1) DK0384279T3 (fr)
ES (1) ES2052988T3 (fr)
FI (1) FI900760A7 (fr)
IE (1) IE63880B1 (fr)
IL (1) IL93427A (fr)
NO (1) NO172117C (fr)
NZ (1) NZ232550A (fr)
PT (1) PT93160B (fr)
ZA (1) ZA901189B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA92970B (en) * 1991-02-12 1992-10-28 Hoechst Ag Arylsulfonylureas,processes for their preparation,and their use as herbicides and growth regulators
DE4109735A1 (de) * 1991-03-25 1992-10-01 Boehringer Mannheim Gmbh Neue sulfonamide, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US6653331B2 (en) * 1996-07-03 2003-11-25 Pharmacia & Upjohn Company Targeted drug delivery using sulfonamide derivatives
US6284923B1 (en) * 1997-08-22 2001-09-04 Tularik Inc Substituted benzene compounds as antiproliferative and cholesterol lowering action
AU759255B2 (en) 1998-01-29 2003-04-10 Amgen, Inc. PPAR-gamma modulators
US6583157B2 (en) 1998-01-29 2003-06-24 Tularik Inc. Quinolinyl and benzothiazolyl modulators
WO1999067258A1 (fr) 1998-06-25 1999-12-29 Tularik Inc. Phosphates d'arylsulfonanilide
US6153585A (en) * 1998-07-20 2000-11-28 Tularik Inc. Arylsulfonanilide derivatives
DK1115701T3 (da) * 1998-09-23 2003-06-23 Tularik Inc Arylsulfonanilidurinstoffer
US7041691B1 (en) 1999-06-30 2006-05-09 Amgen Inc. Compounds for the modulation of PPARγ activity
DE19941559A1 (de) 1999-09-01 2001-03-15 Aventis Pharma Gmbh Verwendung von Bissulfonamiden zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Hyperlipidömie
US6653332B2 (en) * 2000-05-03 2003-11-25 Tularik Inc. Combination therapeutic compositions and method of use
US20030171399A1 (en) * 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
AU2002234165A1 (en) 2000-11-03 2002-05-27 Tularik, Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
CA2555914A1 (fr) * 2004-03-08 2005-09-22 Amgen Inc. Modulation therapeutique de l'activite de recepteur de ppar-gamma
CN114129577B (zh) * 2021-12-15 2022-07-12 徐州医科大学 苯磺酰胺化合物在制备预防和/或治疗衰老疾病的药物中的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA618769A (en) * 1961-04-18 Tagmann Eugen Process for the manufacture of sulfamyl-anilines
US2236168A (en) * 1940-02-27 1941-03-25 Du Pont Lubricant
US3165550A (en) * 1960-06-29 1965-01-12 Pfizer & Co C N-substituted p-benzenedisulfonamides
DE1278443C2 (de) * 1963-11-30 1975-07-24 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4-disulfonamid-1-chlorbenzolen
US3678039A (en) * 1967-04-27 1972-07-18 Lincoln Harvey Werner 4-trifluoromethyl-anthranilic acids
US3737316A (en) * 1971-08-31 1973-06-05 Eastman Kodak Co Two-equivalent sulfonamido couplers
CA1072359A (fr) * 1974-10-08 1980-02-26 Hiroyuki Konishi Methode de controle de la croissance des plantes
US4013621A (en) * 1975-04-29 1977-03-22 Ciba-Geigy Corporation Substituted sulfonamide derivatives of hindered phenols and stabilized compositions
DE3713757A1 (de) * 1987-04-24 1988-11-10 Hoechst Ag Benzolsulfonamidderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
KR900012898A (ko) 1990-09-03
NO172117C (no) 1993-06-09
PT93160A (pt) 1990-08-31
KR0175298B1 (ko) 1999-04-01
FI900760A7 (fi) 1990-08-19
IE900588L (en) 1990-08-18
DK0384279T3 (da) 1994-08-08
PT93160B (pt) 1995-12-29
JPH02255652A (ja) 1990-10-16
CA2010272C (fr) 1999-11-16
IE63880B1 (en) 1995-06-14
DE59005304D1 (de) 1994-05-19
IL93427A (en) 1994-10-21
ZA901189B (en) 1990-10-31
JP2851108B2 (ja) 1999-01-27
NO172117B (no) 1993-03-01
FI900760A0 (fi) 1990-02-15
EP0384279B1 (fr) 1994-04-13
AU4985190A (en) 1990-08-23
AU622765B2 (en) 1992-04-16
IL93427A0 (en) 1990-11-29
NO900750D0 (no) 1990-02-16
NO900750L (no) 1990-08-20
DE3905075A1 (de) 1990-08-30
EP0384279A1 (fr) 1990-08-29
ATE104273T1 (de) 1994-04-15
NZ232550A (en) 1992-05-26
US5143937A (en) 1992-09-01
ES2052988T3 (es) 1994-07-16

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